K. Schmiegelow
Clinical Professor
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Association between Maternal Hormonal Contraception Use and Central Nervous System Tumors in Children
Hargreave, M., Mørch, L. S., Winther, J. F., Schmiegelow, Kjeld & Kjær, Susanne Krüger, 2022, In: JAMA - Journal of the American Medical Association. 327, 1, p. 59-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association between Fertility Treatment and Cancer Risk in Children
Hargreave, M., Jensen, A., Hansen, M. K., Dehlendorff, C., Winther, J. F., Schmiegelow, Kjeld & Kjær, Susanne Krüger, 2019, In: J A M A: The Journal of the American Medical Association. 322, 22, p. 2203-2210 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA polymerase gamma variants and hepatotoxicity during maintenance therapy of childhood acute lymphoblastic leukemia: is there a causal relationship?
Harju, T., Hurme-Niiranen, A., Suo-Palosaari, M., Nygaard Nielsen, S., Hinttala, R., Schmiegelow, Kjeld, Uusimaa, J., Harila, A. & Niinimäki, R., 2023, In: Pharmacogenomics Journal. 23, 5, p. 105-111 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Need for Hospitalization due to SARS-CoV-2 in Children: A Population-based Estimate
Hartling, U. B., Holm, M., Glenthoej, J. P., Cortes, D., Kruse, A., Schmidt, L. S., Lindhard, M. S., Heilskov Rytter, M. J., Zaharov, T., Petersen, J. J. H., Andersen, R. M., Lemvik, G., Nissen, S. K., Marcinski, P. A., Thaarup, J., Jensen, L. H., Lawaetz, M. C., Borch, L., Vissing, N. H., Schmiegelow, K. & 1 others, , 2021, In: Pediatric Infectious Disease Journal. 40, 6, p. E250-E251 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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The preleukemic TCF3-PBX1 gene fusion can be generated in utero and is present in ≈0.6% of healthy newborns
Hein, D., Dreisig, K., Metzler, M., Izraeli, S., Schmiegelow, Kjeld, Borkhardt, A. & Fischer, U., 2019, In: Blood. 134, 16, p. 1355-1358 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Characteristics of white blood cell count in acute lymphoblastic leukemia: A COST LEGEND phenotype-genotype study
Helenius, M., Vaitkeviciene, G., Abrahamsson, J., Jonsson, Ó. G., Lund, B., Harila-Saari, A., Vettenranta, K., Mikkel, S., Stanulla, M., Lopez-Lopez, E., Waanders, E., Madsen, H. O., Marquart, Hanne Vibeke Hansen, Modvig, S., Gupta, R., Schmiegelow, Kjeld & Nielsen, R. L., 2022, In: Pediatric Blood and Cancer. 69, 6, p. e29582Research output: Contribution to journal › Journal article › Research › peer-review
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Facilitation of school re-entry and peer acceptance of children with cancer: a review and meta-analysis of intervention studies
Helms, A. S., Schmiegelow, Kjeld, Brok, J., Johansen, Christoffer, Thorsteinsson, Troels, Simovska, V. & Larsen, H. B., Jan 2016, In: European Journal of Cancer Care. 25, 1, p. 170-179 10 p.Research output: Contribution to journal › Review › Research › peer-review
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PEG-asparaginase allergy in children with acute lymphoblastic leukemia in the NOPHO ALL2008 protocol
Henriksen, L. T., Harila-Saari, A., Ruud, E., Abrahamsson, J., Pruunsild, K., Vaitkeviciene, G., Jónsson, Ó. G., Schmiegelow, Kjeld, Heyman, M., Schrøder, H., Albertsen, B. K. & Nordic Society of Paediatric Haematology and Oncology (NOPHO) group, N. S. O. P. H. A. O. (. G., Mar 2015, In: Pediatric Blood & Cancer. 62, 3, p. 427-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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T-cell ALL in ataxia telangiectasia cured with only 7 weeks of anti-leukemic therapy
Hersby, D. S., Sehested, A., Kristensen, K. & Schmiegelow, Kjeld, Mar 2015, In: Journal of Pediatric Hematology/Oncology. 37, 2, p. 154-5 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Presence of clone-specific markers at birth in children with acute lymphoblastic leukaemia
Hjalgrim, L. L., Madsen, H. O., Melbye, M., Christiansen, M., Andersen, M. T., Pallisgaard, N., Hokland, P., Clausen, N., Schmiegelow, Kjeld & Hjalgrim, Henrik, 2002, In: British Journal of Cancer. 87, 9, p. 994-999 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Birth weight and risk for childhood leukemia in Denmark, Sweden, Norway, and Iceland
Hjalgrim, L., Rostgaard, K., Hjalgrim, Henrik, Westergaard, T., Thomassen, H., Forestier, E., Gustafsson, G., Kristinsson, J., Melbye, M. & Schmiegelow, Kjeld, 20 Oct 2004, In: National Cancer Institute. Journal (Online). 96, 20, p. 1549-1556Research output: Contribution to journal › Journal article › Research › peer-review
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Age- and sex-specific incidence of childhood leukemia by immunophenotype in the Nordic countries
Hjalgrim, L. L., Rostgaard, K., Schmiegelow, Kjeld, Söderhäll, S., Kolmannskog, S., Vettenranta, K., Kristinsson, J., Clausen, N., Melbye, M., Hjalgrim, Henrik & Gustafsson, G., 15 Oct 2003, In: Journal of the National Cancer Institute. 95, 20, p. 1539-1544 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Birth weight as a risk factor for childhood leukemia: A meta-analysis of 18 epidemiologic studies
Hjalgrim, L. L., Westergaard, T., Rostgaard, K., Schmiegelow, Kjeld, Melbye, M., Hjalgrim, Henrik & Engels, E. A., 15 Oct 2003, In: American Journal of Epidemiology. 158, 8, p. 724-735 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical impact of leukemic blast heterogeneity at diagnosis in cytogenetic intermediate-risk acute myeloid leukemia
Hoffmann, M. H., Klausen, T. W., Boegsted, M., Larsen, S. F., Schmitz, A., Leinø, E. B., Schmiegelow, Kjeld, Hasle, H., Bergmann, O. J., Sorensen, S., Nyegaard, M., Dybkaer, K. & Johnsen, H. E., 2012, In: Cytometry. Part B: Clinical Cytometry. 82, 3, p. 123-31 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multisystem inflammatory syndrome in children occurred in one of four thousand children with severe acute respiratory syndrome coronavirus 2
Holm, M., Hartling, U. B., Schmidt, Lisbeth Samsø, Glenthøj, J. P., Kruse, A., Rytter, Maren Johanne Heilskov, Lindhard, M. S., Lawaetz, M. C., Zaharov, T., Petersen, Jens, Andersen, R. M., Lemvik, G., Marcinski, P., Thaarup, J., Jensen, Lise Heilmann, Borch, L., Nielsen, A. B., Vissing, N. H., Schmiegelow, Kjeld & Nygaard, Ulrikka, Sep 2021, In: Acta Paediatrica, International Journal of Paediatrics. 110, 9, p. 2581-2583 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interactions Between Thiopurine Metabolites, Adalimumab, and Antibodies Against Adalimumab in Previously Infliximab-Treated Patients with Inflammatory Bowel Disease
Holmstrøm, R. B., Mogensen, D. V., Brynskov, J., Ainsworth, M. A., Nersting, J., Schmiegelow, Kjeld & Steenholdt, C., 2018, In: Digestive Diseases and Sciences. 63, 6, p. 1583-1591 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment
Hrusak, O., Kalina, T., Wolf, J., Balduzzi, A., Provenzi, M., Rizzari, C., Rives, S., del Pozo Carlavilla, M., Alonso, M. E. V., Domínguez-Pinilla, N., Bourquin, J. P., Schmiegelow, K., Attarbaschi, A., Grillner, P., Mellgren, K., van der Werff ten Bosch, J., Pieters, R., Brozou, T., Borkhardt, A., Escherich, G. & 21 others, , 2020, In: European Journal of Cancer. 132, p. 11-16 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia
Hrusak, O., de Haas, V., Stancikova, J., Vakrmanova, B., Janotova, I., Mejstrikova, E., Capek, V., Trka, J., Zaliova, M., Luks, A., Bleckmann, K., Möricke, A., Irving, J., Konatkowska, B., Alexander, T. B., Inaba, H., Schmiegelow, K., Stokley, S., Zemanova, Z., Moorman, A. V. & 27 others, , 2018, In: Blood. 132, 3, p. 264-276 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic predisposition to PEG-asparaginase hypersensitivity in children treated according to NOPHO ALL2008
the Nordic Society of Paediatric Haematology Oncology (NOPHO) group, T. N. S. O. P. H. O. (. G., 2019, In: British Journal of Haematology. 184, 3, p. 405-417 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low burden of minimal residual disease prior to transplantation in children with very high risk acute lymphoblastic leukaemia: The NOPHO ALL2008 experience
Ifversen, M., Turkiewicz, D., Marquart, H. V., Winiarski, J., Buechner, J., Mellgren, K., Arvidson, J., Rascon, J., Körgvee, L. T., Madsen, H. O., Abrahamsson, J., Lund, B., Jonsson, O. G., Heilmann, C., Heyman, M., Schmiegelow, Kjeld & Vettenranta, K., 2019, In: British Journal of Haematology. 184, 6, p. 982-993Research output: Contribution to journal › Journal article › Research › peer-review
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A qualitative study of adolescent cancer survivors perspectives on social support from healthy peers – A RESPECT study
Ingersgaard, M. V., Fridh, M. K., Thorsteinsson, Troels, Adamsen, L., Schmiegelow, Kjeld & Larsen, Hanne Bækgaard, 2021, In: Journal of Advanced Nursing. 77, 4, p. 1911-1920 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A qualitative study of decision-making on Phase III randomized clinical trial participation in paediatric oncology: Adolescents’ and parents’ perspectives and preferences
Ingersgaard, M. V., Tulstrup, M., Schmiegelow, Kjeld & Larsen, H. B., 1 Jan 2018, In: Journal of Advanced Nursing. 74, 1, p. 110-118 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liquid chromatography-tandem mass spectrometry quantification of 6-thioguanine in DNA using endogenous guanine as internal standard
Jacobsen, J. H., Schmiegelow, Kjeld & Nersting, J., 2012, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 881-882, p. 115-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Polygenic risk score-analysis of thromboembolism in patients with acute lymphoblastic leukemia
Jarvis, K. B., Nielsen, R. L., Gupta, R., Hede, F. D., Huttunen, P., Jónsson, Ó. G., Rank, C. U., Ranta, S., Saks, K., Trakymiene, S. S., Tuckuviene, R., Tulstrup, Morten Rytter, Ruud, E., Schmiegelow, Kjeld, LeBlanc, M. & the INVENT consortium, T. I. C., 2020, In: Thrombosis Research. 196, p. 15-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Candidate single nucleotide polymorphisms and thromboembolism in acute lymphoblastic leukemia – A NOPHO ALL2008 study
Jarvis, K. B., LeBlanc, M., Tulstrup, M., Nielsen, R. L., Albertsen, B. K., Gupta, R., Huttunen, P., Jónsson, Ó. G., Rank, C. U., Ranta, S., Ruud, E., Saks, K., Trakymiene, S. S., Tuckuviene, R. & Schmiegelow, Kjeld, 2019, In: Thrombosis Research. 184, p. 92-98 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Doing less, accomplishing more for childhood ALL: response
Jensen, K., Oskarsson, T., Lahteenmaki, P., Flaegstad, T., Schmiegelow, Kjeld, Vedsted, P., Albertsen, B. & Schrøder, H., 2022, In: British Journal of Haematology. 197, 1, p. 120-120Research output: Contribution to journal › Comment/debate › Research › peer-review
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Detection mode of childhood acute lymphoblastic leukaemia relapse and its effect on survival: a Nordic population-based cohort study
the Nordic Society of Paediatric Haematology and Oncology (NOPHO), T. N. S. O. P. H. A. O. (., 2021, In: British Journal of Haematology. 194, 4, p. 734-744 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Health care utilisation preceding relapse or second malignant neoplasm after childhood acute lymphoblastic leukaemia: A population-based matched cohort study
Jensen, K. S., Klug Albertsen, B., Schrøder, H., Zalounina Falborg, A., Schmiegelow, Kjeld, Rosthøj, S., Callesen, M. T. & Vedsted, P., 2021, In: BMJ Open. 11, 8, e050285.Research output: Contribution to journal › Journal article › Research › peer-review
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Health care utilisation following childhood acute lymphoblastic leukaemia: a population-based matched cohort study
Jensen, K. S., Klug Albertsen, B., Schrøder, H., Zalounina Falborg, A., Schmiegelow, Kjeld, Rosthøj, S., Callesen, M. T. & Vedsted, P., 2021, In: BMJ Open. 11, 11, e049847.Research output: Contribution to journal › Journal article › Research › peer-review
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Temporal changes in incidence of relapse and outcome after relapse of childhood acute lymphoblastic leukemia over three decades; a Nordic population-based cohort study
Jensen, K. S., Oskarsson, T., Lahteenmaki, P. M., Flaegstad, T., Jonsson, O. G., Svenberg, P., Schmiegelow, Kjeld, Heyman, M., Noren-Nystrom, U., Schroder, H. & Albertsen, B. K., 2022, In: Leukemia. 36, 5, p. 1274-1282 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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9p21.3 Microdeletion involving CDKN2A/2B in a young patient with multiple primary cancers and review of the literature
Jensen, M. R., Stoltze, U., Hansen, Thomas van Overeem, Bak, M., Sehested, A., Rechnitzer, C., Mathiasen, René, Scheie, David, Larsen, K. B., Olsen, T. E., Muhic, A., Skjøth, Jane, Rossing, Caroline Maria, Schmiegelow, Kjeld & Wadt, Karin Anna Wallentin, 2022, In: Cold Spring Harbor molecular case studies. 8, 4, a006164.Research output: Contribution to journal › Review › Research › peer-review
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Endocrine Late Effects in Survivors of Cancer in Adolescence and Young Adulthood: A Danish Population-Based Cohort Study
Jensen, M. V., Rugbjerg, K., de Fine Licht, S., Johansen, Christoffer, Schmiegelow, Kjeld, Andersen, K. K. & Winther, J. F., 2018, In: JAMA network open. 1, 2, p. 1-12 e180349.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of NT5C2 Germline Variants on 6-Mecaptopurine Metabolism in Children With Acute Lymphoblastic Leukemia
Jiang, C., Yang, W., Moriyama, T., Liu, C., Smith, C., Yang, W., Qian, M., Li, Z., Tulstrup, Morten Rytter, Schmiegelow, Kjeld, Crews, K. R., Zhang, H., Pui, C. H., Evans, W., Relling, M., Bhatia, S. & Yang, J. J., 2021, In: Clinical Pharmacology and Therapeutics. 109, 3, p. 1538-1545Research output: Contribution to journal › Journal article › Research › peer-review
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Childcare in the first 2 years of life reduces the risk of childhood acute lymphoblastic leukemia
Kamper-Jørgensen, Mads, Woodward, A., Wohlfahrt, J., Benn, C. S., Simonsen, J., Hjalgrim, H. & Schmiegelow, Kjeld, 2008, In: Leukemia. 22, 1, p. 189-193 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A European paediatric cancer mission: aspiration or reality?
Kearns, P. R., Vassal, G., Ladenstein, R., Schrappe, M., Biondi, A., Blanc, P., Eggert, A., Kienesberger, A., Kozhaeva, O., Pieters, R. & Schmiegelow, Kjeld, 2019, In: The Lancet Oncology. 20, 9, p. 1200-1202 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young
Kimura, S., Pölönen, P., Montefiori, L., Caldwell, K., Iacobucci, I., Chen, C., Brown, A., Han, K., Liu, Y., Chang, Y., Cheng, Z., Yinmei, Z., Park, C. S., Mitchell, S., Reyes, N., Yeoh, A., Attarbaschi, A., Moore, A., Manabe, A., Buldini, B. & 54 others, , 2023, In: Blood. 142, Supplement 1, p. 845 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Marriage and divorce among childhood cancer survivors
Koch, S. V., Kejs, A. M. T., Engholm, G., Møller, H., Johansen, C. & Schmiegelow, Kjeld, 2011, In: Pediatric Hematology & Oncology. 33, 7, p. 500-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia
Krali, O., Marincevic-Zuniga, Y., Arvidsson, G., Enblad, A. P., Lundmark, A., Sayyab, S., Zachariadis, V., Heinäniemi, M., Suhonen, J., Oksa, L., Vepsäläinen, K., Öfverholm, I., Barbany, G., Nordgren, A., Lilljebjörn, H., Fioretos, T., Madsen, H. O., Marquart, H. V., Flaegstad, T., Forestier, E. & 10 others, , 2023, In: npj Precision Oncology. 7, 1, 13 p., 131.Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence of non-adherence and non-compliance during maintenance therapy in adults with acute lymphoblastic leukemia and their associations with survival
Kristjánsdóttir, E. R., Toksvang, L. N., Schmiegelow, Kjeld & Rank, C. U., 2022, In: European Journal of Haematology. 108, 2, p. 109-117Research output: Contribution to journal › Journal article › Research › peer-review
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Automatic detection and delineation of pediatric gliomas on combined [18F]FET PET and MRI
Ladefoged, C. N., Henriksen, O. M., Mathiasen, René, Schmiegelow, Kjeld, Andersen, Flemming Littrup, Højgaard, Liselotte, Borgwardt, L., Law, Ian & Marner, Lisbeth, 2022, In: Frontiers in Nuclear Medicine. 2, p. 1-10 :960820.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacokinetics of tablet and liquid formulations of oral 6-mercaptopurine in children with acute lymphoblastic leukemia
Larsen, R. H., Hjalgrim, L. L., Grell, Kathrine, Kristensen, K., Pedersen, L. G., Brünner, E. D., Als-Nielsen, B., Schmiegelow, Kjeld & Nersting, J., 2020, In: Cancer Chemotherapy and Pharmacology. 86, p. 25-32 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increments in DNA-thioguanine level during thiopurine enhanced maintenance therapy of acute lymphoblastic leukemia
Larsen, R. H., Utke Rank, C., Grell, Kathrine, Nørgaard Møller, L., Malthe Overgaard, U., Kampmann, P., Nersting, J., Degn, M., Nygaard Nielsen, S., Holst, H., Klug Albertsen, B., Skov Wehner, P., Thude Callesen, M., Kanerva, J., Leth Frandsen, T., Als-Nielsen, B., Lyngsie Hjalgrim, L. & Schmiegelow, Kjeld, 2021, In: Haematologica. 106, 11, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamics of leucocyte DNA thioguanine nucleotide levels during maintenance therapy of childhood acute lymphoblastic leukemia
Larsen, R. H., Hjalgrim, L. L., Degn, M., Nersting, J., Als-Nielsen, B., Grell, Kathrine & Schmiegelow, Kjeld, 2021, In: Cancer Chemotherapy and Pharmacology. 88, p. 53–60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Whole blood long-chain n-3 fatty acids as a measure of fish oil compliance in children with acute lymphoblastic leukemia: a pilot study
Laumann, R. D., Iversen, T., Frandsen, T. L., Mølgaard, Christian, Stark, K. D., Schmiegelow, Kjeld & Lauritzen, Lotte, 2022, In: Prostaglandins, Leukotrienes & Essential Fatty Acids. 177, 5 p., 102401.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperlipidemia in children and adolescents with acute lymphoblastic leukemia: A systematic review and meta-analysis
Laumann, R. D., Pedersen, L. L., Andrés-Jensen, L., Mølgaard, Christian, Schmiegelow, Kjeld, Frandsen, T. L. & Als-Nielsen, B., 2023, In: Pediatric Blood and Cancer. 70, 12, 15 p., e30683.Research output: Contribution to journal › Review › Research › peer-review
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Characterizing chromosomal break points of t(12;21)[ETV6-RUNX1]-positive leukaemia using multiple tiling PCR on whole-genome-amplified DNA
Lausten-Thomsen, U., Madsen, H. O. & Schmiegelow, Kjeld, 1 Jan 2010, In: Leukemia. 24, 1, p. 203-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ETV6-RUNX1 transcript is not frequent in early human haematopoiesis
Lausten-Thomsen, U., Hjalgrim, H., Marquart, Hanne Vibeke Hansen, Lutterodt, M., Petersen, B. L. & Schmiegelow, Kjeld, 2008, In: European Journal of Haematology. 81, 2, p. 161-162 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adipokines in umbilical cord blood from children born large for gestational age
Lausten-Thomsen, U., Christiansen, M., Hedley, P. L., Holm, Jens-Christian & Schmiegelow, Kjeld, Jan 2016, In: Journal of Pediatric Endocrinology and Metabolism. 29, 1, p. 33-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence of t(12;21)[ETV6-RUNX1]-positive cells in healthy neonates
Lausten-Thomsen, U., Madsen, H. O., Vestergaard, T. R., Hjalgrim, H., Nersting, J. & Schmiegelow, Kjeld, 2011, In: Blood. 117, 1, p. 186-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased risk of ALL among premature infants is not explained by increased prevalence of pre-leukemic cell clones
Lausten-Thomsen, U., Madsen, H. O., Vestergaard, T. R., Hjalgrim, H., Lando, A. & Schmiegelow, Kjeld, 15 Mar 2010, In: Blood Cells, Molecules and Diseases. 44, 3, p. 188-90 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leukemic blasts are present at low levels in spinal fluid in one-third of childhood acute lymphoblastic leukemia cases
Levinsen, M., Marquart, H. V., Groth-Pedersen, L., Abrahamsson, J., Albertsen, B. K., Andersen, M. K., Frandsen, T. L., Harila-Saari, A., Pronk, C. J. H., Ulvmoen, A., Vaitkevičienė, G., Lähteenmäki, P. M., Niinimäki, R., Taskinen, M., Jeppesen, M., Schmiegelow, Kjeld & Nordic Society of Pediatric Hematology and Oncology (NOPHO), N. S. O. P. H. A. O. (., Nov 2016, In: Pediatric Blood & Cancer. 63, 11, p. 1935-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacy and Toxicity of Intrathecal Liposomal Cytarabine in First-line Therapy of Childhood Acute Lymphoblastic Leukemia
Levinsen, M., Harila-Saari, A., Grell, Kathrine, Jonsson, O. G., Taskinen, M., Abrahamsson, J., Vettenranta, K., Åsberg, A., Risteli, J., Heldrup, J. & Schmiegelow, Kjeld, Nov 2016, In: Journal of Pediatric Hematology/Oncology. 38, 8, p. 602-609 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity
Levinsen, M., Rosthøj, Susanne, Nygaard, U., Heldrup, J., Harila-Saari, A., Jonsson, O. G., Bechensteen, A. G., Abrahamsson, J., Lausen, B., L. Frandsen, T., Weinshilboum, R. M. & Schmiegelow, Kjeld, 1 Jan 2015, In: Cancer Chemotherapy and Pharmacology. 75, 1, p. 59-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In sickness and in health: classmates are highly motivated to provide in-hospital support during childhood cancer therapy
Lindgren, L. H., Schmiegelow, Kjeld, Helms, A. S., Thorsteinsson, Troels & Larsen, H. B., Jan 2017, In: Psycho-Oncology. 26, 1, p. 37-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pancreatitis-associated protein as an early marker of asparaginase-associated pancreatitis
Lukes, J., Wolthers, B. O., Altaf Raja, R., Uhrinova, K., Skvarova Kramarzova, K., Hermanova, I., Simcikova, M., Kicko, P., Zaliova, M., Sramkova, L., Stary, J., Trka, J., Schmiegelow, Kjeld & Starkova, J., 2021, In: Leukemia and Lymphoma. 62, 14, p. 3506-3510Research output: Contribution to journal › Letter › Research › peer-review
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Risk factors for treatment related mortality in childhood acute lymphoblastic leukaemia
Lund, B., Åsberg, A., Heyman, M., Kanerva, J., Harila-Saari, A., Hasle, H., Söderhäll, S., Jónsson, Ó. G., Lydersen, S., Schmiegelow, Kjeld & Nordic Society of Paediatric Haematology and Oncology, N. S. O. P. H. A. O., 1 Apr 2011, In: Pediatric Blood & Cancer. 56, 4, p. 551-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Archival bone marrow samples: suitable for multiple biomarker analysis?
Lund, B., Najmi, L. A., Wesolowska-Andersen, A., Landsem, V. M., Rasmussen, K. K., Borst, L., Gupta, R., Schmiegelow, Kjeld & Klungland, H., Jan 2015, In: Applied Immunohistochemistry & Molecular Morphology. 23, 1, p. 71-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A systematic review of studies on psychosocial late effects of childhood cancer: structures of society and methodological pitfalls may challenge the conclusions
Lund, L. W., Schmiegelow, Kjeld, Rechnitzer, C. & Johansen, C., 1 Apr 2011, In: Pediatric Blood & Cancer. 56, 4, p. 532-43 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antidepressant use in siblings of children with cancer: A danish population-based cohort study
Lund, L. W., Winther, J. F., Kristiansen, Luise Cederkvist, Rechnitzer, C., Dalton, Susanne Oksbjerg, Appel, C. W., Schmiegelow, Kjeld & Johansen, Christoffer, 2020, In: JNCI Cancer Spectrum. 4, 5, pkaa046.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased risk of antidepressant use in childhood cancer survivors: a Danish population-based cohort study
Lund, L. W., Winther, J. F., Kristiansen, Luise Cederkvist, Andersen, K. K., Dalton, S. O., Appel, C. W., Rechnitzer, C., Schmiegelow, Kjeld & Johansen, C., Mar 2015, In: European journal of cancer (Oxford, England : 1990). 51, 5, p. 675-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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All-cause mortality rates and home deaths decreased in children with life-limiting diagnoses in Denmark between 1994 and 2014
Lykke, C., Ekholm, O., Schmiegelow, Kjeld, Olsen, M. & Sjøgren, P., 2018, In: Acta Paediatrica. 107, 10, p. 1781-1785 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anxiety and Depression in Bereaved Parents After Losing a Child due to Life-Limiting Diagnoses: A Danish Nationwide Questionnaire Survey
Lykke, C., Ekholm, O., Schmiegelow, Kjeld, Olsen, M. & Sjøgren, P., Oct 2019, In: Journal of Pain and Symptom Management. 58, 4, p. 596-604Research output: Contribution to journal › Journal article › Research › peer-review
- Published
End-of-life communication: a nationwide study of bereaved parents' perceptions
Lykke, C., Ekholm, O., Schmiegelow, Kjeld, Olsen, M. & Sjøgren, P., 2022, In: BMJ Supportive and Palliative Care. 12, e4, p. E616-E622Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Asparaginase encapsulated in erythrocytes as second-line treatment in hypersensitive patients with acute lymphoblastic leukaemia
Lynggaard, L. S., Vaitkeviciene, G., Langenskiöld, C., Lehmann, A. K., Lähteenmäki, P. M., Lepik, K., El Hariry, I., Schmiegelow, Kjeld & Albertsen, B. K., 2022, In: British Journal of Haematology. 197, 6, p. 745-754 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PEG-asparaginase treatment regimens for acute lymphoblastic leukaemia in children: a network meta-analysis
Lynggaard, L. S., Rank, C. U., Als-Nielsen, B., Hoejfeldt, S. G., Heyman, M., Schmiegelow, Kjeld & Albertsen, B. K., 2023, In: Cochrane Database of Systematic Reviews. 2023, 5, 68 p., CD014570.Research output: Contribution to journal › Review › Research › peer-review
- Published
Asparaginase enzyme activity levels and toxicity in childhood acute lymphoblastic leukemia: a NOPHO ALL2008 study
Lynggaard, L. S., Rank, C. U., Hansen, S. N., Højfeldt, S. G., Henriksen, L. T., Jarvis, K. B., Ranta, S., Niinimaki, R., Harila-Saari, A., Wolthers, B. O., Frandsen, T. L., Heyman, M., Schmiegelow, Kjeld & Albertsen, B. K., 2022, In: Blood advances. 6, 1, p. 138-147 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dic(9;20)(p13;q11) in childhood acute lymphoblastic leukaemia is related to low cellular resistance to asparaginase, cytarabine and corticosteroids
Lönnerholm, G., Nordgren, A., Frost, B., Jonsson, O. G., Kanerva, J., Nygaard, R., Schmiegelow, Kjeld, Larsson, R. & Forestier, E., 2008, In: Leukemia. 23, 1, p. 209-12 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro cellular drug resistance adds prognostic information to other known risk-factors in childhood acute lymphoblastic leukemia
Lönnerholm, G., Thörn, I., Sundström, C., Frost, B., Flaegstad, T., Heyman, M., Jonsson, O. G., Harila-Saari, A., Madsen, H. O., Porwit, A., Schmiegelow, Kjeld, Söderhäll, S., Wesenberg, F., Vettenranta, K., Larsson, R. & Forestier, E., 2011, In: Leukemia Research. 35, 4, p. 472-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Birth weight in offspring and leukaemia risk in parents-A nation-wide register-based cohort study from Denmark
Marklund, M., Rostgaard, K., Hjalgrim, L., Schmiegelow, Kjeld & Hjalgrim, H., 2013, In: Leukemia Research. 37, 2, p. 129-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association meta-analysis of single-nucleotide polymorphisms and symptomatic venous thromboembolism during therapy for acute lymphoblastic leukemia and lymphoma in caucasian children
Mateos, M. K., Tulstrup, M., Quinn, M. C. J., Tuckuviene, R., Marshall, G. M., Gupta, R., Mayoh, C., Wolthers, B. O., Barbaro, P. M., Ruud, E., Sutton, R., Huttunen, P., Revesz, T., Trakymiene, S. S., Barbaric, D., Tedgård, U., Giles, J. E., Alvaro, F., Jonsson, O. G., Mechinaud, F. & 8 others, , 2020, In: Cancers. 12, 5, 1285.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Management of CNS Disease in Pediatric Acute Lymphoblastic Leukemia
McNeer, J. L. & Schmiegelow, Kjeld, 2022, In: Current Hematologic Malignancy Reports. 17, 1, p. 1-14 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Plasma cytokine profiles at diagnosis in pediatric patients with non-hodgkin lymphoma
Mellgren, K., Hedegaard, C. J., Schmiegelow, Kjeld & Müller, K., 2012, In: Pediatric Hematology & Oncology. 34, 4, p. 271-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Minimal residual disease, long-term outcome, and IKZF1 deletions in children and adolescents with Down syndrome and acute lymphocytic leukaemia: a matched cohort study
Michels, N., Boer, J. M., Enshaei, A., Sutton, R., Heyman, M., Ebert, S., Fiocco, M., de Groot-Kruseman, H. A., van der Velden, V. H. J., Barbany, G., Escherich, G., Vora, A., Trahair, T., Dalla-Pozza, L., Pieters, R., zur Stadt, U., Schmiegelow, Kjeld, Moorman, A. V., Zwaan, C. M. & den Boer, M. L., 2021, In: The Lancet Haematology. 8, 10, p. e700-e710Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia
Milani, L., Lundmark, A., Kiialainen, A., Nordlund, J., Flaegstad, T., Forestier, E., Heyman, M., Jonmundsson, G., Kanerva, J., Schmiegelow, Kjeld, Söderhäll, S., Gustafsson, M., Lönnerholm, G. & Syvänen, A., 11 Feb 2010, In: Blood. 115, 6, p. 1214-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Allele-specific gene expression patterns in primary leukemic cells reveal regulation of gene expression by CpG site methylation
Milani, L., Lundmark, A., Nordlund, J., Kiialainen, A., Flaegstad, T., Jonmundsson, G., Kanerva, J., Schmiegelow, Kjeld, Gunderson, K. L., Lönnerholm, G. & Syvänen, A., 2008, In: Genome Research. 19, 1, p. 1-11 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mass spectrometry-based proteomics of cerebrospinal fluid in pediatric central nervous system malignancies: a systematic review with meta-analysis of individual patient data
Larsen, Christian Mirian, Thastrup, M., Mathiasen, R., Schmiegelow, Kjeld, Olsen, Jesper Velgaard & Østergaard, Ole, 2024, In: Fluids and Barriers of the CNS. 21, 17 p., 14.Research output: Contribution to journal › Review › Research › peer-review
- Published
Value of flow cytometry for MRD-based relapse prediction in B-cell precursor ALL in a multicenter setting
Modvig, S., Hallböök, H., Madsen, H. O., Siitonen, S., Rosthøj, S., Tierens, A., Juvonen, V., Osnes, L. T. N., Vålerhaugen, H., Hultdin, M., Matuzeviciene, R., Stoskus, M., Marincevic, M., Lilleorg, A., Ehinger, M., Norén-Nystrøm, U., Toft, N., Taskinen, M., Jónsson, O. G., Pruunsild, K. & 7 others, , 2021, In: Leukemia. 35, p. 1894–1906 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Minimal residual disease quantification by flow cytometry provides reliable risk stratification in T-cell acute lymphoblastic leukemia
Modvig, S., Madsen, H. O., Siitonen, S. M., Rosthøj, S., Tierens, A., Juvonen, V., Osnes, L. T. N., Vålerhaugen, H., Hultdin, M., Thörn, I., Matuzeviciene, R., Stoskus, M., Marincevic, M., Fogelstrand, L., Lilleorg, A., Toft, N., Jónsson, O. G., Pruunsild, K., Vaitkeviciene, G., Vettenranta, K. & 4 others, , 2019, In: Leukemia. 33, p. 1324–1336 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High CD34 surface expression in BCP-ALL predicts poor induction therapy response and is associated with altered expression of genes related to cell migration and adhesion
Modvig, S., Wernersson, R., Øbro, N. F., Olsen, L. R., Christensen, C., Rosthøj, Susanne, Degn, M., Jürgensen, G. W., Madsen, H. O., Albertsen, B. K., Wehner, P. S., Rosthøj, S., Lilljebjörn, H., Fioretos, T., Schmiegelow, Kjeld & Marquart, Hanne Vibeke Hansen, 2022, In: Molecular Oncology. 16, 10, p. 2015-2030 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A role for thiopurine metabolites in the synergism between thiopurines and infliximab in inflammatory bowel disease
Mogensen, D. V., Brynskov, J., Ainsworth, M. A., Nersting, J., Schmiegelow, Kjeld & Steenholdt, C., 2018, In: Journal of Crohn's and Colitis. 12, 3, p. 298-305Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute Lymphoblastic Leukemia Influences Lipid Metabolism at Time of Diagnosis
Mogensen, P. R., Schmiegelow, Kjeld, Grell, Kathrine, Wolthers, B. O., Mogensen, S. S. & Frandsen, T. L., 2018, In: Pediatric Blood & Cancer. 65, p. S143 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Association between body mass index and pancreatitis in children with acute lymphoblastic leukemia
Mogensen, P. R., Wolthers, B. O., Grell, Kathrine, Schmiegelow, Kjeld & Frandsen, T. L., Aug 2018, In: Pediatric Blood & Cancer. 65, 8, 3 p., e27071.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dyslipidemia at diagnosis of childhood acute lymphoblastic leukemia
Mogensen, P. R., Grell, Kathrine, Schmiegelow, Kjeld, Overgaard, U. M., Wolthers, B. O., Mogensen, S. S., Vaag, A. & Frandsen, T. L., 2020, In: PLoS ONE. 15, 4, 17 p., e0231209.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperlipidemia is a risk factor for osteonecrosis in children and young adults with acute lymphoblastic leukemia
Mogensen, S. S., Schmiegelow, Kjeld, Grell, Kathrine, Albertsen, B. K., Wehner, P. S., Kampmann, P. & Frandsen, T. L., May 2017, In: Haematologica. 102, p. e175-e178Research output: Contribution to journal › Letter › Research › peer-review
- Published
Comparing osteonecrosis clinical phenotype, timing, and risk factors in children and young adults treated for acute lymphoblastic leukemia
Mogensen, S. S., Harila-Saari, A., Mäkitie, O., Myrberg, I. H., Niinimäki, R., Vestli, A., Hafsteinsdottir, S., Griškevicius, L., Saks, K., Hallböök, H., Retpen, J., Helt, L. R., Toft, N., Schmiegelow, Kjeld, Frandsen, T. L. & Nordic Society of Paediatric Haematology and Oncology (NOPHO) group, N. S. O. P. H. A. O. (. G., 2018, In: Pediatric Blood & Cancer. 65, 10, 10 p., e27300.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of inherited NUDT15 polymorphisms on thiopurine active metabolites in Japanese children with acute lymphoblastic leukemia
Moriyama, T., Nishii, R., Lin, T. N., Kihira, K., Toyoda, H., Nersting, J., Kato, M., Koh, K., Inaba, H., Manabe, A., Schmiegelow, Kjeld, Yang, J. J. & Hori, H., 2017, In: Pharmacogenetics and Genomics. 27, 6, p. 236-239 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity
Moriyama, T., Nishii, R., Perez-Andreu, V., Yang, W., Klussmann, F. A., Zhao, X., Lin, T-N., Hoshitsuki, K., Nersting, J., Kihira, K., Hofmann, U., Komada, Y., Kato, M., McCorkle, R., Li, L., Koh, K., Najera, C. R., Kham, S. K-Y., Isobe, T., Chen, Z. & 14 others, , Apr 2016, In: Nature Genetics. 48, 4, p. 367-73 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Refining risk prediction in pediatric acute lymphoblastic leukemia through DNA methylation profiling
Mosquera Orgueira, A., Krali, O., Pérez Míguez, C., Peleteiro Raíndo, A., Díaz Arias, J. Á., González Pérez, M. S., Pérez Encinas, M. M., Fernández Sanmartín, M., Sinnet, D., Heyman, M., Lönnerholm, G., Norén-Nyström, U., Schmiegelow, Kjeld & Nordlund, J., 2024, In: Clinical Epigenetics. 16, 1, 13 p., 49.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meropenem to Children with Febrile Neutropenia Induces Monoresistant Pseudomonas aeruginosa
Mønster, M. B., Vissing, N. H., Schrøder, H., Grosen, D., Rosthøj, S., Frimodt-Møller, N., Wang, M., Schønheyder, H. C., Schmiegelow, Kjeld, Justesen, U. S. & Nygaard, Ulrikka, 2020, In: Journal of Pediatric Hematology/Oncology. 42, 8, p. e783-e787Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thiopurine 6TG treatment increases tumor immunogenicity and response to immune checkpoint blockade
Nazerai, L., Willis, S. C., Yankilevich, P., Di Leo, L., Bosisio, F. M., Frias, A., Bertolotto, C., Nersting, J., Thastrup, M., Buus, Søren, Thomsen, Allan Randrup, Nielsen, M., Rohrberg, K. S., Schmiegelow, Kjeld & de Zio, Daniela, 2023, In: OncoImmunology. 12, 1, 16 p., 2158610.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Methotrexate polyglutamate levels and co-distributions in childhood acute lymphoblastic leukemia maintenance therapy
Nersting, J., Nielsen, S. N., Grell, Kathrine, Paerregaard, M., Abrahamsson, J., Lund, B., Jonsson, O. G., Pruunsild, K., Vaitkeviciene, G., Kanerva, J., Schmiegelow, Kjeld & Nordic Society of Paediatric Haematology and Oncology (NOPHO), N. S. O. P. H. A. O. (., 2019, In: Cancer Chemotherapy and Pharmacology. 83, 1, p. 53-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacogenomics of methotrexate: moving towards individualized therapy
Nersting, J. & Schmiegelow, Kjeld, 2009, In: Pharmacogenomics. 10, 12, p. 1887-9 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia
Nersting, J., Borst, L. & Schmiegelow, Kjeld, 2011, In: Clinical Proteomics. 8, 1, p. 8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of methylene tetrahydrofolate reductase polymorphisms and coadministration of antimetabolites on toxicity after high dose methotrexate
Niekerk, P. B. V. K., Schmiegelow, Kjeld & Schroeder, H., 2008, In: European Journal of Haematology. 81, 5, p. 391-398 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peripherally applied opioids for postoperative pain: evidence of an analgesic effect? A systematic review and meta-analysis
Nielsen, B. N., Henneberg, S. W., Schmiegelow, Kjeld, Friis, S. M. & Rømsing, J., Aug 2015, In: Acta Anaesthesiologica Scandinavica. 59, 7, p. 830-45 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of topical morphine for treatment of oral mucositis in cancer patients
Nielsen, B. N., Friis, S. M., Schmiegelow, Kjeld, Henneberg, S. & Romsing, J., 2021, In: British Journal of Pain. 15, 4, p. 409–417Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physician-defined severe toxicities occurring during and after cancer treatment: Modified consensus definitions and clinical applicability in the evaluation of cancer treatment
Nielsen, C. G., Thomsen, Birthe Lykke Riegels, Als-Nielsen, B., Conyers, R., Jeha, S., Mateos, M. K., Mlynarski, W., Pieters, R., Rathe, M., Schmiegelow, Kjeld, Andres-Jensen, L. & Ponte Legno Severe Toxicity, P. L. S. T., 2023, In: Frontiers in Pediatrics. 11, 10 p., 1155449.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-like growth factor II mRNA, peptides, and receptors in a thoracopulmonary malignant small round cell tumor
Nielsen, F. C., Orskov, C., Haselbacher, G., Ramlau, J., Christiansen, Jan, Schmiegelow, Kjeld & Rehfeld, Jens Frederik, 1994, In: Cancer. 73, 4, p. 1312-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cationic amphiphilic drugs induce elevation in lysoglycerophospholipid levels and cell death in leukemia cells
Nielsen, I. Ø., Groth-Pedersen, L., Dicroce-Giacobini, J., Jonassen, A. S. H., Mortensen, M., Bilgin, M., Schmiegelow, Kjeld, Jaattela, Marja & Maeda, K., 2020, In: Metabolomics. 16, 9, 91.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testing physical function in children undergoing intense cancer treatment-a RESPECT feasibility study
Nielsen, M. K. F., Christensen, J. F., Frandsen, T. L., Thorsteinsson, Troels, Andersen, L. B., Christensen, Karl Bang, Nersting, J., Faber, M., Schmiegelow, Kjeld & Larsen, H. B., 2018, In: Pediatric Blood & Cancer. 65, 8, 9 p., e27100.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8780
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Cerebellar mutism syndrome in children with brain tumours of the posterior fossa
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298
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Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients
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Intermittent Versus Continuous PEG-Asparaginase to Reduce Asparaginase-Associated Toxicities: A NOPHO ALL2008 Randomized Study
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