Frederik Diness
Guest researcher, Guest Researcher
- Published
Synthesis of 3-Boc-(1,3)-oxazinane-protected amino aldehydes from amino acids and their conversion into urea precursors. Novel building blocks for combinatorial synthesis
Diness, Frederik, Beyer, J. & Meldal, Morten Peter, Apr 2004, In: Molecular Informatics. 23, 2-3, p. 130-144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
INTRAMOLECULAR CARBAMOYLIMINIUM ACTIVATED SOLID PHASE PICTET-SPENGLER REACTIONS. TOWARDS MCR AGONISTS
Diness, Frederik, Beyer, J. & Meldal, Morten Peter, 2004, In: Journal of Peptide Science. 10, p. 126-126Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amino acid derived 1,4-dialkyl substituted imidazolones
Diness, Frederik & Meldal, Morten Peter, 11 Mar 2010, In: Biopolymers. 94, 2, p. 236-241Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Catalyst-Free N-Arylation Using Unactivated Fluorobenzenes
Diness, Frederik & Fairlie, D. P., 2012, In: Angewandte Chemie International Edition. 51, 32, p. 8012-8016Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid-phase reactions of N-carbamyliminium ions: from amino aldehydes to on-bead GPCR-screening : PH.D. thesis
Diness, Frederik, 2006, Copenhagen: Department of Medical Chemistry, Danish University of Pharmaceutical Sciences. 179 p.Research output: Book/Report › Book › Research
- Published
Synthesis of the thiazole-thiazoline fragment of largazole analogues
Diness, Frederik, Nielsen, D. S. & Fairlie, D. P., 2 Dec 2011, In: Journal of Organic Chemistry. 76, 23, p. 9845-9851Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual approach to intramolecular carbamoyliminium activated solid phase Pictet-Spengler reactions
Diness, Frederik & Meldal, Morten Peter, 2005, Peptides 2004, Proceedings. p. 208-209Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Sequential direct SNAr reactions of pentafluorobenzenes with azole or indole derivatives
Diness, Frederik & Begtrup, M., 2014, In: Organic Letters. 16, 11, p. 3130-3133 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Advances in merging triazoles with peptides and proteins
Diness, Frederik, Schoffelen, S. & Meldal, Morten Peter, 2017, [Awaiting title]. Springer, p. 1-38 38 p. (Topics in Heterocyclic Chemistry).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Fluorobenzene derivatives as multifunctional tools
Diness, Frederik, Begtrup, M. B. & Fairlie, D. P., 25 Mar 2012, In: American Chemical Society. Abstracts of Papers (at the National Meeting). 243Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Imidazolones in diastereoselective cyclization reactions and Cu(II)-catalysed cross-coupling reactions
Diness, Frederik & Meldal, Morten Peter, 20 Jul 2009, In: Chemistry: A European Journal. 15, 29, p. 7044-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Solid-phase synthesis of tetrahydro-beta-carbolines and tetrahydroisoquinolines by stereoselective intramolecular N-carbamyliminium Pictet-Spengler reactions
Diness, Frederik & Meldal, Morten Peter, 25 Oct 2006, In: Chemistry: A European Journal. 12, 31, p. 8056-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fmox: a base-labile aldehyde protecting group
Diness, Frederik & Meldal, Morten Peter, 2015, In: European Journal of Organic Chemistry. 2015, 7, p. 1433-1436 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and stability of strongly acidic benzamide derivatives
Diness, Frederik, Bjerrum, N. J. & Begtrup, M., 2018, In: Beilstein Journal of Organic Chemistry. 14, p. 523-530 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metallo-Organozymes with Specific Proteolytic Activity
Embaby, A. M., Lelieveldt, L. P. W. M., Diness, Frederik & Meldal, Morten Peter, 2018, In: Chemistry - A European Journal. 24, 66, p. 17424-17428 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rational Tuning of Fluorobenzene Probes for Cysteine-Selective Protein Modification
Embaby, A. M., Schoffelen, S., Kofoed, Christian, Meldal, Morten Peter & Diness, Frederik, 2 Jul 2018, In: Angewandte Chemie International Edition. 57, 27, p. 8022-8026 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Self-Promoted Glycosylation of Carbamoylated Peptides on Solid Phase
Fischer, Niklas Henrik, Vævest, B. N., Dam, Andreas Ketilsø, Diness, Frederik & Pedersen, Christian Marcus, 2024, (Accepted/In press) In: ChemPlusChem. e202400066.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C-Terminal lactamization of peptides
Fischer, Niklas Henrik, Nielsen, D. S., Palmer, D., Meldal, Morten Peter & Diness, Frederik, 2021, In: Chemical Communications. 57, 7, p. 895-898 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tuning Peptide Structure and Function through Fluorobenzene Stapling
Fischer, Niklas Henrik, Fumi, E., Oliveira, M. T., Thulstrup, Peter Waaben & Diness, Frederik, 2022, In: Chemistry: A European Journal. 28, 8, 7 p., e202103788.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radiolabeled albumin through SNAr of cysteines as a potential pretargeting theranostic agent
Fischer, Niklas Henrik, van den Broek, S. I. L. I., Herth, Matthias Manfred & Diness, Frederik, 2022, In: RSC Advances. 12, 54, p. 35032-35036Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chemical modification of proteins - challenges and trends at the start of the 2020s
Fischer, Niklas Henrik, Oliveira, M. T. & Diness, Frederik, 2023, In: Biomaterials Science. 11, 3, p. 719–748 30 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Identifying a compound modifying a cellular response, comprises attaching cells having a reporter system onto solid supports, releasing a library member, screening and identifying target cells
Hagel, G., Thastrup, Ole, Meldal, Morten Peter, Norrild, J. C., Hentzer, M., Norrild, J. & Diness, Frederik, 29 Dec 2011, IPC No. G01N 35/ 00 A N, Patent No. US2011319274, Priority date 25 May 2005, Priority No. WO2005DK00348Research output: Patent
- Published
C-Terminally modified peptides via cleavage of the HMBA linker by O-, N- or S-nucleophiles
Hansen, J., Diness, Frederik & Meldal, Morten Peter, 2016, In: Organic & Biomolecular Chemistry. 14, 12, p. 3238-3245 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Constraining cyclic peptides to mimic protein structure motifs
Hill, T. A., Shepherd, N. E., Diness, Frederik & Fairlie, D. P., 2014, In: Angewandte Chemie - International Edition. 53, 48, p. 13020-13041 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twists or turns: stabilising alpha vs. beta turns in tetrapeptides
Hoang, H. N., Hill, T. A., Ruiz-Gómez, G., Diness, Frederik, Mason, J. M., Wu, C., Abbenante, G., Shepherd, N. E. & Fairlie, D. P., 2019, In: Chemical Science. 10, 45, p. 10595-10600Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustainable Flow Synthesis of Encoded Beads for Combinatorial Chemistry and Chemical Biology
Hu, H., Nikitin, S., Berthelsen, A. B., Diness, Frederik, Schoffelen, S. & Meldal, Morten Peter, 13 Aug 2018, In: ACS Combinatorial Science. 20, 8, p. 492-498 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Computational Evolution of Threonine-Rich β-Hairpin Peptides Mimicking Specificity and Affinity of Antibodies
Hu, H., Kofoed, Christian, Li, M., Gonçalves, J. P. L., Hansen, J., Wolfram, M., Hansen, Axel Kornerup, Hansen, Camilla Hartmann Friis, Diness, Frederik, Schoffelen, S. & Meldal, Morten Peter, 27 Feb 2019, In: ACS Central Science. 5, 2, p. 259-269 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Azotides as Modular Peptide-Based Ligands for Asymmetric Lewis Acid Catalysis
Jacobsen, C. B., Nielsen, D. S., Meldal, Morten Peter & Diness, Frederik, 7 Jun 2019, In: Journal of Organic Chemistry. 84, 11, p. 6940-6945 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism and Scope of Base-Controlled Catalyst-Free N-Arylation of Amines with Unactivated Fluorobenzenes
Jacobsen, C. B., Meldal, Morten Peter & Diness, Frederik, 2017, In: Chemistry: A European Journal. 23, 4, p. 846-851 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biophysical characterization of the proton-coupled oligopeptide transporter YjdL
Jensen, J. M., Simonsen, F. C., Mastali, A., Hald, H., Lillebro, I., Diness, Frederik, Olsen, L. & Mirza, Osman Asghar, Nov 2012, In: Peptides. 38, 1, p. 89-93 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
X-ray diffraction data as a source of the vibrational free-energy contribution in polymorphic systems
Kofoed, P. M., Hoser, A. A., Diness, Frederik, Capelli, S. C. & Madsen, Anders Østergaard, 2019, In: IUCrJ. 6, 4, p. 558-571 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design and Combinatorial Development of Shield-1 Peptide Mimetics Binding to Destabilized FKBP12
Madsen, D., Jørgensen, F. P., Palmer, D., Roux, M. E., Olsen, J. V., Bols, Mikael, Schoffelen, S., Diness, Frederik & Meldal, Morten Peter, 2020, In: ACS Combinatorial Science. 22, 3, p. 156-164Research output: Contribution to journal › Journal article › Research › peer-review
Ralph F. Hirschmann award address 2009: merger of organic chemistry with peptide diversity
Meldal, Morten Peter, Tornøe, C. W., Nielsen, T. E., Diness, Frederik, Le Quement, S. T., Christensen, C. A., Jensen, J. F., Worm-Leonhard, K., Groth, T., Bouakaz, L., Wu, B., Hagel, G. & Keinicke, L., 2010, In: Biopolymers. 94, 2, p. 161-182 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent Fascinating Aspects of the CuAAC Click Reaction
Meldal, Morten Peter & Diness, Frederik, 1 Jun 2020, In: Trends in Chemistry. 2, 6, p. 569-584 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
D-amino acid adhesion peptides by combinatorial selection: control of cellular growth on inert surfaces
Meldal, Morten Peter, Wu, B., Diness, Frederik, Michael, R., Hagel, G., Nygaard, J. & Martinez, K., 2012, In: Journal of Peptide Science. 18, S1, p. S21-S22 2 p., IL1.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Total synthesis, structure, and oral absorption of a thiazole cyclic peptide, sanguinamide A
Nielsen, D. S., Hoang, H. N., Lohman, R., Diness, Frederik & Fairlie, D. P., 16 Nov 2012, In: Organic Letters. 14, 22, p. 5720-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Pictet-Spengler reaction in solid-phase combinatorial chemistry
Nielsen, T. E., Diness, Frederik & Meldal, Morten Peter, Nov 2003, In: Current Opinion in Drug Discovery & Development. 6, 6, p. 801-14 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lignin-Inspired Polybenzylethersulfone Synthesis via SNAr Reaction
Nikitin, S., Lie, Yann & Diness, Frederik, 2022, In: Macromolecular Chemistry and Physics. 223, 13, p. 2100484 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Tuning Green Explosives through SNAr Chemistry
Nikitin, S. & Diness, Frederik, 2024, (Accepted/In press) In: Chemistry - An Asian Journal.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative studies of adhesion peptides based on L- or D-amino acids
Nikitin, S., Palmer, D., Meldal, Morten Peter & Diness, Frederik, 2016, In: Journal of Peptide Science. 22, 10, p. 642-646 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Click-Chemistry-Mediated Synthesis of Selective Melanocortin Receptor 4 Agonists
Palmer, D., Gonçalves, J. P. L., Hansen, L. V., Wu, B., Hald, H., Schoffelen, S., Diness, Frederik, Le Quement, S. T., Nielsen, Thomas Eiland & Meldal, Morten Peter, 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 8716-8730 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diversity-Oriented Syntheses by Combining CuAAC and Stereoselective INCIC Reactions with Peptides
Wang, Y., Madsen, Anders Østergaard, Diness, Frederik & Meldal, Morten Peter, 2017, In: Chemistry - A European Journal. 23, 56, p. 13869–13874 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dihydroquinazolinones via A3‐Type Reactions of N‐Carbamoyliminium Ions
Wang, Y., Oliveira, M. T., Madsen, D., Thompson, A., Meldal, Morten Peter & Diness, Frederik, 2020, In: Chemistry: A European Journal. 26, 68, p. 15825-15829 6 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Probing the aglycon binding site of a beta-glucosidase: a collection of C-1-modified 2,5-dideoxy-2,5-imino-D-mannitol derivatives and their structure-activity relationships as competitive inhibitors
Wrodnigg, T. M., Diness, Frederik, Gruber, C., Häusler, H., Lundt, I., Rupitz, K., Steiner, A. J., Stütz, A. E., Tarling, C. A., Withers, S. G. & Wölfler, H., 1 Jul 2004, In: Bioorganic & Medicinal Chemistry. 12, 13, p. 3485-95 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carbon dioxide enhances sulphur-selective conjugate addition reactions
Yang, Y., Fischer, Niklas Henrik, Oliveira, M. T., Hadaf, Gul Barg, Liu, J., Brock-Nannestad, Theis, Diness, Frederik & Lee, Ji-Woong, 2022, In: Organic & Biomolecular Chemistry. 20, 22, p. 4526–4533 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Comparative α-helicity of cyclic pentapeptides in water
de Araujo, A. D., Hoang, H. N., Kok, W. M., Diness, Frederik, Gupta, P., Driver, R. W., Price, D. A., Liras, S. & Fairlie, D. P., 2014, In: Angewandte Chemie International Edition. 53, 27, p. 6965-6969 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 33654400
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272
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C-Terminally modified peptides via cleavage of the HMBA linker by O-, N- or S-nucleophiles
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
251
downloads
X-ray diffraction data as a source of the vibrational free-energy contribution in polymorphic systems
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
157
downloads
Design and Combinatorial Development of Shield-1 Peptide Mimetics Binding to Destabilized FKBP12
Research output: Contribution to journal › Journal article › Research › peer-review
Published