Katrine Ter-Borch Gram Schjoldager
Associate Professor - Promotion Programme
Glycomics Program
Blegdamsvej 3, 2200 København N.
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Glycoproteomics
Bagdonaite, Ieva , Malaker, S. A., Polasky, D. A., Riley, N. M., Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Halim, Adnan, Aoki-Kinoshita, K. F., Nesvizhskii, A. I., Bertozzi, C. R., Wandall, Hans H., Parker, B. L., Thaysen-Andersen, M. & Scott, N. E., 2022, In: Nature Reviews Methods Primers. 2, 1, 29 p., 48.Research output: Contribution to journal › Review › Research › peer-review
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Rescue of Drosophila Melanogaster l(2)35Aa lethality is only mediated by polypeptide GalNAc-transferase pgant35A, but not by the evolutionary conserved human ortholog GalNAc-transferase-T11
Bennett, Eric Paul, Chen, Y., Schwientek, T., Mandel, Ulla, Schjoldager, Katrine Ter-Borch Gram, Cohen, S. M. & Clausen, Henrik, 2010, In: Glycoconjugate Journal. 27, 4, p. 435-44 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Shaping Glycans by DNA Scissors: Turning Glycosciences Into Lego Toying
Clausen, Henrik, Schjoldager, Katrine Ter-Borch Gram, Yang, Zhang, Steentoft, C., Halim, Adnan, Bennett, E. & Vakhrushev, Sergey, Nov 2015, In: Glycobiology. 25, 11, p. 1233-1233 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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A systematic study of modulation of ADAM-mediated ectodomain shedding by site-specific O-glycosylation
Goth, C. K., Halim, Adnan, Khetarpal, S. A., Rader, D. J., Clausen, Henrik & Schjoldager, Katrine Ter-Borch Gram, 24 Nov 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 47, p. 14623-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Site-specific O-Glycosylation by Polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-transferase T2) Co-regulates β1-Adrenergic Receptor N-terminal Cleavage
Goth, C. K., Tuhkanen, H. E., Khan, H., Lackman, J. J., Wang, S., Narimatsu, Yoshiki, Hansen, L. H., Overall, C. M., Clausen, Henrik, Schjoldager, Katrine Ter-Borch Gram & Petäjä-Repo, U. E., 2017, In: The Journal of Biological Chemistry. 292, 11, p. 4714-4726 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fine-tuning limited proteolysis - A novel role for regulated site-specific O-glycosylation in beta 1-Adrenergic Receptor cleavage and function
Goth, C. K., Tuhkanen, H. E., Khan, H., Wang, S., Narimatsu, Yoshiki, Hansen, L. H., Overall, C., Clausen, Henrik, Schjoldager, Katrine Ter-Borch Gram & Petaja-Repo, U., Dec 2017, In: Glycobiology. 27, 12, p. 1204-1204 84.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Fine-Tuning Limited Proteolysis: A Major Role for Regulated Site-Specific O-Glycosylation
Goth, C. K., Vakhrushev, Sergey, Joshi, Hiren Jitendra, Clausen, Henrik & Schjoldager, Katrine Ter-Borch Gram, 2018, In: Trends in Biochemical Sciences. 43, 4, p. 269-284 16 p.Research output: Contribution to journal › Review › Research › peer-review
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A systematic study of site-specific GalNAc-type O-glycosylation modulating proprotein convertase processing
Schjoldager, Katrine Ter-Borch Gram, Vester-Christensen, M. B., Goth, C. K., Petersen, T. N., Brunak, Søren, Bennett, Eric Paul, Levery, S. B. & Clausen, Henrik, 18 Nov 2011, In: Journal of Biological Chemistry. 286, 46, p. 40122-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A glycogene mutation map for discovery of diseases of glycosylation
Hansen, Lars, Lind-Thomsen, A., Joshi, Hiren Jitendra, Pedersen, N. B., Have, C. T., Kong, Y., Wang, S., Sparso, T., Grarup, Niels, Vester-Christensen, M. B., Schjoldager, Katrine Ter-Borch Gram, Freeze, H. H., Hansen, Torben, Pedersen, Oluf Borbye, Henrissat, B., Mandel, Ulla, Clausen, Henrik, Wandall, Hans H. & Bennett, Eric Paul, 2015, In: Glycobiology. 25, 2, p. 211-224 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor
Hansen, L. H., Madsen, Thomas Daugbjerg, Goth, C. K., Clausen, Henrik, Chen, Y., Dzhoyashvili, N., Iyer, S. R., Sangaralingham, S. J., Burnett, J. C., Rehfeld, Jens Frederik, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram & Goetze, Jens P. , 2019, In: Journal of Biological Chemistry. 294, 34, p. 12567-12578 12 p.Research output: Contribution to journal › Review › Research › peer-review
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Chromogranin A in the mammalian heart: Expression without secretion
Hansen, L. H., Darkner, S., Svendsen, Jesper Hastrup, Henningsen, K., Pehrson, S., Chen, X., Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram & Goetze, Jens P. , Jul 2017, In: Biomarkers in Medicine. 11, 7, p. 541-545 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines
Hintze, John, Ye, Z., Narimatsu, Yoshiki, Madsen, Thomas Daugbjerg, Joshi, Hiren Jitendra, Goth, C. K., Linstedt, A., Bachert, C., Mandel, Ulla, Bennett, Eric Paul, Vakhrushev, Sergey & Schjoldager, Katrine Ter-Borch Gram, 2018, In: The Journal of Biological Chemistry. 293, 49, p. 19064-19077 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GlycoDomainViewer: A bioinformatics tool for contextual exploration of glycoproteomes
Joshi, Hiren Jitendra, Jørgensen, A., Schjoldager, Katrine Ter-Borch Gram, Halim, Adnan, Dworkin, L. A., Steentoft, C., Wandall, Hans H., Clausen, Henrik & Vakhrushev, Sergey, 1 Mar 2018, In: Glycobiology. 28, 3, p. 131-136 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SnapShot: O-Glycosylation Pathways across Kingdoms
Joshi, Hiren Jitendra, Narimatsu, Yoshiki, Schjoldager, Katrine Ter-Borch Gram, Tytgat, H. L. P., Aebi, M., Clausen, Henrik & Halim, Adnan, Jan 2018, In: Cell. 172, 3, p. 632–632.e2Research output: Contribution to journal › Review › Research › peer-review
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Protein O-Galnac Glycosylation: Most Complex and Differentially Regulated PTM
Joshi, Hiren Jitendra, Steentoft, C., Schjoldager, Katrine Ter-Borch Gram, Vakhrushev, Sergey, Wandall, Hans H. & Clausen, Henrik, 1 Jan 2015, Glycoscience: Biology and Medicine. Springer, p. 1049-1064 16 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseases
Joshi, Hiren Jitendra, Hansen, Lars, Narimatsu, Yoshiki, Freeze, H. H., Henrissat, B., Bennett, Eric Paul, Wandall, Hans H., Clausen, Henrik & Schjoldager, Katrine Ter-Borch Gram, 2018, In: Glycobiology. 28, 5, p. 284-294Research output: Contribution to journal › Journal article › Research › peer-review
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Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents
Khetarpal, S. A., Schjoldager, K. T., Christoffersen, C., Raghavan, A., Edmondson, A. C., Reutter, H. M., Ahmed, B., Ouazzani, R., Peloso, G. M., Vitali, C., Zhao, W., Somasundara, A. V. H., Millar, J. S., Park, Y., Fernando, G., Livanov, V., Choi, S., Noé, E., Patel, P., Ho, S. P. & 12 others, , 9 Aug 2016, In: Cell Metabolism. 24, 2, p. 234-245 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation
King, S. L., Goth, C. K., Eckhard, U., Joshi, Hiren Jitendra, Haue, Amalie Dahl, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram, Overall, C. M. & Wandall, Hans H., 2018, In: The Journal of Biological Chemistry. 293, 20, p. 7629-7644 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterizing the O-glycosylation landscape of human plasma, platelets, and endothelial cells
King-Smith, S. L., Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Halim, Adnan, Madsen, Thomas Daugbjerg, Dziegiel, Morten Hanefeld, Woetmann, Anders , Vakhrushev, Sergey & Wandall, Hans H., 2017, In: Blood advances. 1, 7, p. 429-442 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis
Kong, Y., Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Madsen, Thomas Daugbjerg, Gerken, T. A., Vester-Christensen, M. B., Wandall, Hans H., Bennett, Eric Paul, Levery, S. B., Vakhrushev, Sergey & Clausen, Henrik, Jan 2015, In: Glycobiology. 25, 1, p. 55-65 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase
Larsen, I. S. B., Povolo, Lorenzo, Zhou, L., Tian, W., Mygind, Kasper Johansen, Hintze, John, Jiang, C., Hartill, V., Prescott, K., Johnson, C. A., Mullegama, S. V., McConkie-Rosell, A., McDonald, M., Hansen, Lars, Vakhrushev, Sergey, Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik, Worzfeld, T., Joshi, Hiren Jitendra & Halim, Adnan, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 21, p. e2302584120Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of distinct glycoforms of IgA1 in plasma from patients with IgA nephropathy and healthy individuals
Lehoux, S., Mi, R., Aryal, R. P., Wang, Y., Schjoldager, Katrine Ter-Borch Gram, Clausen, Henrik, Van Die, I., Han, Y., Chapman, A. B., Cummings, R. D. & Ju, T., Nov 2014, In: Molecular & Cellular Proteomics. 13, 11, p. 3097-113 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
Madsen, Thomas Daugbjerg, Hansen, L. H., Hintze, John, Ye, Z., Jebari, S., Andersen, Daniel Bjørklund, Joshi, Hiren Jitendra, Ju, T., Goetze, Jens P. , Martin, C., Rosenkilde, Mette, Holst, Jens Juul, Kuhre, Rune Ehrenreich, Goth, C. K., Vakhrushev, Sergey & Schjoldager, Katrine Ter-Borch Gram, 2020, In: Nature Communications. 11, 1, 13 p., 4033.Research output: Contribution to journal › Journal article › Research › peer-review
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A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome
Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Zhang, Y., Gomes, C., Chen, Yen-Hsi, Lorenzetti, F., Furukawa, S., Schjoldager, Katrine Ter-Borch Gram, Hansen, Lars, Clausen, Henrik, Bennett, Eric Paul & Wandall, Hans H., 2018, In: Glycobiology. 28, 5, p. 295–305Research output: Contribution to journal › Journal article › Research › peer-review
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An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells
Narimatsu, Y., Joshi, H. J., Nason, R., Van Coillie, J., Karlsson, R., Sun, L., Ye, Z., Chen, Y-H., Schjoldager, K. T., Steentoft, C., Furukawa, S., Bensing, B. A., Sullam, P. M., Thompson, A. J., Paulson, J. C., Büll, C., Adema, G. J., Mandel, U., Hansen, L., Bennett, E. P. & 4 others, , 2019, In: Molecular Cell. 75, 2, p. 394-407, e1-e5Research output: Contribution to journal › Journal article › Research › peer-review
ID: 920646
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109
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Discovery of O-glycans on atrial natriuretic peptide (ANP) that affect both its proteolytic degradation and potency at its cognate receptor
Research output: Contribution to journal › Review › Research › peer-review
Published -
103
downloads
An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
34
downloads
The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase
Research output: Contribution to journal › Journal article › Research › peer-review
Published