Thomas Werge

100 ancient genomes show repeated population turnovers in Neolithic Denmark

Allentoft, M. E., Sikora, M., Fischer, A., Sjögren, K-G., Ingason, A., Macleod, R., Rosengren, A., Schulz Paulsson, B., Jørkov, M. L. S., Novosolov, M., Stenderup, J., Price, T. D., Mortensen, M. F., Nielsen, A. B., Hede, M. U., Sørensen, L., Nielsen, P. O., Rasmussen, P., Jensen, T. Z. T., Refoyo-Martínez, A. & 48 others, Irving-Pease, Evan, Barrie, William, Pearson, A., Sousa da Mota, B., Demeter, Fabrice, Henriksen, Rasmus Henrik Amund, Vimala, Tharsika, McColl, Hugh, Vaughn, Andrew Howland, Vinner, Lasse, Renaud, Gabriel, Stern, A., Johannsen, N. N., Ramsøe, Abigail Daisy, Schork, A. J., Ruter, Anthony Henry, Gotfredsen, Anne Birgitte, Nielsen, B. H., Petersen, Erik Brinch, Kannegaard, E., Hansen, J., Pedersen, K. B., Pedersen, L., Klassen, L., Meldgaard, Morten, Johansen, M., Uldum, O. C., Lotz, P., Lysdahl, P., Bangsgaard, Pernille, Petersen, P. V., Maring, R., Iversen, Rune, Wåhlin, S., Sørensen, S. A., Andersen, S. H., Jørgensen, T., Lynnerup, Niels, Lawson, D. J., Rasmussen, Simon, Korneliussen, Thorfinn Sand, Kjær, Kurt H., Durbin, R., Nielsen, Rasmus, Delaneau, O., Werge, Thomas, Kristiansen, Kristian & Willerslev, Eske, 2024, In: Nature. 625, 7994, p. 329-337 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Polygenic Analyses Show Important Differences Between Major Depressive Disorder Symptoms Measured Using Various Instruments

Huang, L., Tang, S., Rietkerk, J., Appadurai, V., Krebs, M. D., Schork, A. J., Werge, Thomas, Zuber, V., Kendler, K. & Cai, N., 2024, (Accepted/In press) In: Biological Psychiatry. 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder

LaBianca, S., Brikell, I., Helenius, D., Loughnan, R., Mefford, J., Palmer, C. E., Walker, R., Gådin, J. R., Krebs, M., Appadurai, V., Vaez, M., Agerbo, E., Pedersen, M. G., Børglum, A. D., Hougaard, D. M., Mors, O., Nordentoft, M., Mortensen, P. B., Kendler, K. S., Jernigan, T. L. & 7 others, Geschwind, D. H., Ingason, A., Dahl, A. W., Zaitlen, N., Dalsgaard, S., Werge, Thomas & Schork, A. J., 2024, In: Nature Genetics. 56, 2, p. 234-244 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Population genomics of post-glacial western Eurasia

Allentoft, M. E., Sikora, M., Refoyo-Martínez, A., Irving-Pease, E. K., Fischer, A., Barrie, W., Ingason, A., Stenderup, J., Sjögren, K-G., Pearson, A., da Mota, B. S., Paulsson, B. S., Halgren, A., Macleod, R., Jørkov, M. L. S., Demeter, F., Sørensen, L., Nielsen, P. O., Henriksen, R. A., Vimala, T. & 144 others, McColl, Hugh, Margaryan, Ashot, Ilardo, M., Vaughn, Andrew Howland, Mortensen, M. F., Nielsen, A. B., Hede, M. U., Johannsen, N. N., Rasmussen, P., Vinner, Lasse, Renaud, Gabriel, Stern, A., Jensen, Theis Zetner Trolle, Scorrano, Gabriele, Schroeder, Hannes, Lysdahl, P., Ramsøe, Abigail Daisy, Skorobogatov, A., Schork, A. J., Rosengren, A., Ruter, Anthony Henry, Outram, A., Timoshenko, A. A., Buzhilova, A., Coppa, A., Zubova, A., Silva, A. M., Hansen, Anders Johannes, Gromov, A., Logvin, A., Gotfredsen, Anne Birgitte, Nielsen, B. H., González-Rabanal, B., Lalueza-Fox, C., McKenzie, C. J., Gaunitz, Charleen, Blasco, C., Liesau, C., Martinez-Labarga, C., Pozdnyakov, D. V., Cuenca-Solana, D., Lordkipanidze, D. O., En’shin, D., Salazar-García, D. C., Price, T. D., Borić, D., Kostyleva, E., Veselovskaya, E. V., Usmanova, E. R., Cappellini, Enrico, Petersen, Erik Brinch, Kannegaard, E., Radina, F., Yediay, Fulya Eylem, Duday, H., Gutiérrez-Zugasti, I., Merts, I., Potekhina, I., Shevnina, I., Altinkaya, Isin, Guilaine, J., Hansen, J., Tortosa, J. E. A., Zilhão, J., Vega, J., Pedersen, K. B., Tunia, K., Zhao, Lei, Mylnikova, L. N., Larsson, L., Metz, L., Yepiskoposyan, L., Pedersen, L., Sarti, L., Orlando, L., Slimak, L., Klassen, L., Blank, M., González-Morales, M., Silvestrini, M., Vretemark, M., Nesterova, M. S., Rykun, M., Rolfo, M. F., Szmyt, M., Przybyła, M., Calattini, M., Sablin, M., Dobisíková, M., Meldgaard, Morten, Johansen, M., Berezina, N., Card, N., Saveliev, N. A., Poshekhonova, O., Rickards, O., Lozovskaya, O. V., Gábor, O., Uldum, O. C., Aurino, P., Kosintsev, P., Courtaud, P., Ríos, P., Mortensen, P., Lotz, P., Persson, P., Bangsgaard, Pernille, de Barros Damgaard, P., Vang Petersen, P., Martinez, P. P., Włodarczak, P., Smolyaninov, R. V., Maring, R., Menduiña, R., Badalyan, R., Iversen, Rune, Turin, R., Vasilyev, S., Wåhlin, S., Borutskaya, S., Skochina, S., Sørensen, S. A., Andersen, S. H., Jørgensen, T., Serikov, Y. B., Molodin, V. I., Smrcka, V., Merts, V., Appadurai, V., Moiseyev, V., Magnusson, Y., Kjær, Kurt H., Lynnerup, Niels, Lawson, D. J., Sudmant, P. H., Rasmussen, Simon, Korneliussen, Thorfinn Sand, Durbin, R., Nielsen, Rasmus, Delaneau, O., Werge, Thomas, Racimo, Fernando, Kristiansen, Kristian & Willerslev, Eske, 2024, In: Nature. 625, 7994, p. 301-311

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of women at high risk of postpartum psychiatric episodes: A population-based study quantifying relative and absolute risks following exposure to selected risk factors and genetic liability

Johannsen, B. M. W., Larsen, J. T., Liu, X., Madsen, K. B., Mægbæk, M. L., Albiñana, C., Bergink, V., Laursen, T. M., Bech, B. H., Mortensen, P. B., Nordentoft, Merete, Børglum, A. D., Werge, Thomas, Hougaard, D. M., Agerbo, E., Petersen, L. V. & Munk-Olsen, T., 23 Oct 2023, (E-pub ahead of print) In: Acta Psychiatrica Scandinavica. 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A study of the genetic architecture of social responsiveness in families with parental schizophrenia or bipolar disorder and population-based controls

Veddum, L., Greve, A. N., Gregersen, M., Andreassen, A. K., Knudsen, C. B., Brandt, J. M., Krantz, M. F., Søndergaard, A., Burton, B. K., Jepsen, J. R. M., Hemager, N., Werge, Thomas, Thorup, Anne, Nordentoft, Merete, Mors, O. & Nudel, R., 2023, In: Psychiatry Research. 326, 115280.

Research output: Contribution to journal › Journal article › Research › peer-review

ADuLT: An efficient and robust time-to-event GWAS

Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Steinbach, J., Krebs, M. D., Hougaard, D. M., Werge, Thomas, Nordentoft, Merete, Børglum, A. D., Musliner, K. L., Ganna, A., Schork, A. J., Mortensen, P. B., McGrath, J. J., Privé, F. & Vilhjálmsson, B. J., 2023, In: Nature Communications. 14, 12 p., 5553.

Research output: Contribution to journal › Journal article › Research › peer-review

Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks

Appadurai, V., Bybjerg-Grauholm, J., Krebs, M. D., Rosengren, A., Buil, A., Ingason, A., Mors, O., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Mortensen, P. B., Delaneau, O., Werge, Thomas & Schork, A. J., 2023, In: Communications Biology . 6, 101.

Research output: Contribution to journal › Journal article › Research › peer-review

An immunogenetic investigation of 30 autoimmune and autoinflammatory diseases and their links to psychiatric disorders in a nationwide sample

Nudel, R., Allesøe, R. L., Werge, Thomas, Thompson, W. K., Rasmussen, Simon & Benros, Michael Eriksen, 2023, In: Immunology. 168, 4, p. 622-639

Research output: Contribution to journal › Journal article › Research › peer-review

Associations of psychiatric disorders with sex chromosome aneuploidies in the Danish iPSYCH2015 dataset: a case-cohort study

Sánchez, X. C., Montalbano, S., Vaez, M., Krebs, M. D., Byberg-Grauholm, J., Mortensen, P. B., Børglum, A. D., Hougaard, D. M., Nordentoft, Merete, Geschwind, D. H., Buil Demur, Alfonso Alberto, Schork, A. J., Thompson, W. K., Raznahan, A., Helenius, D., Werge, Thomas & Ingason, A., 2023, In: The Lancet Psychiatry. 10, 2, p. 129-138 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

COVID-19 illness severity and 2-year prevalence of physical symptoms: an observational study in Iceland, Sweden, Norway and Denmark

Shen, Q., Joyce, E. E., Ebrahimi, O. V., Didriksen, M., Lovik, A., Sævarsdóttir, K. S., Magnúsdóttir, I., Mikkelsen, D. H., Unnarsdóttir, A. B., Hauksdóttir, A., Hoffart, A., Kähler, A. K., Thórdardóttir, E. B., Eythórsson, E., Frans, E. M., Tómasson, G., Ask, H., Hardardóttir, H., Jakobsdóttir, J., Lehto, K. & 12 others, Lu, L., Andreassen, O. A., Sullivan, P. F., Pálsson, R., Erikstrup, C., Ostrowski, Sisse Rye, Werge, Thomas, Aspelund, T., Pedersen, Ole Birger Vesterager, Johnson, S. U., Fang, F. & Valdimarsdóttir, U. A., 2023, In: The Lancet Regional Health - Europe. 35, 12 p., 100756.

Research output: Contribution to journal › Journal article › Research › peer-review

Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study

Pan, M., Roe, J. M., Nudel, R., Schork, A. J., Iakunchykova, O., Fjell, A. M., Walhovd, K. B., Werge, Thomas, Chen, C., Benros, Michael Eriksen & Wang, Y., 2023, In: Translational Psychiatry. 13, 174.

Research output: Contribution to journal › Journal article › Research › peer-review

Cohort Profile: The Danish Blood Donor Study

Erikstrup, C., Sørensen, E., Nielsen, K. R., Bruun, M. T., Petersen, M. S., Rostgaard, K., Thørner, L. W., Larsen, M., Mikkelsen, S., Dinh, K. M., Schwinn, M., Rigas, A. S., Didriksen, M., Dowsett, J., von Stemann, J. H., Brodersen, T., Paulsen, I. W., Hindhede, L., Sækmose, S. G., Kaspersen, K. A. & 10 others, Boldsen, J. K., Kjerulff, B., Werge, Thomas, Brunak, Søren, Banasik, Karina, Hansen, Thomas Folkmann, Ullum, H., Hjalgrim, Henrik, Ostrowski, Sisse Rye & Pedersen, Ole Birger Vesterager, 2023, In: International Journal of Epidemiology. 52, 3, p. e162-e171 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

DNA-methylation and immunological response in medication overuse headache

Carlsen, L. N., Hansen, C. S., Kogelman, L. J. A., Werge, Thomas, Ullum, H., Bybjerg-Grauholm, J., Hansen, Thomas Folkmann & Jensen, Rigmor Højland, 2023, In: Cephalalgia. 43, 3, p. 1-11

Research output: Contribution to journal › Journal article › Research › peer-review

DanMAC5: a browser of aggregated sequence variants from 8,671 whole genome sequenced Danish individuals

Banasik, K., Møller, P. L., Techlo, T. R., Holm, P. C., Walters, G. B., Ingason, A., Rosengren, A., Rohde, P. D., Kogelman, L. J. A., Westergaard, D., Siggaard, T., Chmura, P. J., Chalmer, M. A., Magnússon, Ó., Þórisson, G., Stefánsson, H., Guðbjartsson, D. F., Stefánsson, K., Olesen, J., Winther, S. & 5 others, Bøttcher, M., Brunak, Søren, Werge, Thomas, Nyegaard, M. & Hansen, Thomas Folkmann, 2023, In: BMC Genomic Data. 24, 1, 4 p., 30.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Deep Learning for Cross-Diagnostic Prediction of Mental Disorder Diagnosis and Prognosis Using Danish Nationwide Register and Genetic Data

Allesøe, R. L., Thompson, W. K., Bybjerg-Grauholm, J., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2023, In: JAMA Psychiatry. 80, 2, p. 146-155 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses

Als, T. D., Kurki, M. I., Grove, J., Voloudakis, G., Therrien, K., Tasanko, E., Nielsen, T. T., Naamanka, J., Veerapen, K., Levey, D. F., Bendl, J., Bybjerg-Grauholm, J., Zeng, B., Demontis, D., Rosengren, A., Athanasiadis, G., Bækved-Hansen, M., Qvist, P., Bragi Walters, G., Thorgeirsson, T. & 23 others, Stefánsson, H., Musliner, K. L., Rajagopal, V. M., Farajzadeh, L., Thirstrup, J., Vilhjálmsson, B. J., McGrath, J. J., Mattheisen, M., Meier, S., Agerbo, E., Stefánsson, K., Nordentoft, Merete, Werge, Thomas, Hougaard, D. M., Mortensen, P. B., Stein, M. B., Gelernter, J., Hovatta, I., Roussos, P., Daly, M. J., Mors, O., Palotie, A. & Børglum, A. D., 2023, In: Nature Medicine. 29, 7, p. 1832-1844 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Developmental language disorder – a comprehensive study of more than 46,000 individuals

Nudel, R., Christensen, Rikke Vang, Kalnak, N., Schwinn, M., Banasik, Karina, Dinh, K. M., Erikstrup, C., Pedersen, Ole Birger Vesterager, Burgdorf, Kristoffer Sølvsten, Ullum, H., Ostrowski, Sisse Rye, Hansen, Thomas Folkmann, Werge, Thomas & DBDS Genomic Consortium, D. G. C., 2023, In: Psychiatry Research. 323, 9 p., 115171.

Research output: Contribution to journal › Journal article › Research › peer-review

Epidemiological overview of major depressive disorder in Scandinavia using nationwide registers

Pasman, J. A., Meijsen, J. J., Haram, M., Kowalec, K., Harder, A., Xiong, Y., Nguyen, T-D., Jangmo, A., Shorter, J. R., Bergstedt, J., Das, U., Zetterberg, R., Tate, A., Lichtenstein, P., Larsson, H., Odsbu, I., Werge, T., Reichborn-Kjennerud, T., Andreassen, O. A., Sullivan, P. F. & 3 others, Buil, A., Tesli, M. & Lu, Y., 2023, In: The Lancet Regional Health - Europe. 29, 12 p., 100621.

Research output: Contribution to journal › Journal article › Research › peer-review

Experience of loneliness during the COVID-19 pandemic: a cross-sectional study of 50 968 adult Danes

Christoffersen, L. A. N., Helenius, D., Schwinn, M., Erikstrup, C., Hjalgrim, Henrik, Nissen, J., Banasik, Karina, Nielsen, K., Kaspersen, K. A., Dinh, K. M., Bruun, M. T., Ostrowski, Sisse Rye, Sækmose, S., Hansen, Thomas Folkmann, Werge, Thomas, Didriksen, M. & Pedersen, Ole Birger Vesterager, 2023, In: BMJ Open. 13, 4, 9 p., e064033.

Research output: Contribution to journal › Journal article › Research › peer-review

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors

Docherty, A. R., Mullins, N., Ashley-Koch, A. E., Qin, X., Coleman, J. R. I., Shabalin, A., Kang, J. E., Murnyak, B., Wendt, F., Adams, M., Campos, A. I., DiBlasi, E., Fullerton, J. M., Kranzler, H. R., Bakian, A. V., Monson, E. T., Rentería, M. E., Walss-Bass, C., Andreassen, O. A., Behera, C. & 228 others, Bulik, C. M., Edenberg, H. J., Kessler, R. C., John Mann, J., Nurnberger, J. I., Pistis, G., Streit, F., Ursano, R. J., Polimanti, R., Dennis, M., Garrett, M., Hair, L., Harvey, P., Hauser, E. R., Hauser, M. A., Huffman, J., Jacobson, D., Madduri, R., McMahon, B., Oslin, D. W., Trafton, J., Awasthi, S., Berrettini, W. H., Bohus, M., Chang, X., Chen, H. C., Chen, W. J., Christensen, E. D. M. D., Crow, S., Duriez, P., Edwards, A. C., Fernández-Aranda, F., Galfalvy, H., Gandal, M., Gorwood, P., Guo, Y., Hafferty, J. D., Hakonarson, H., Halmi, K. A., Hishimoto, A., Jain, S., Jamain, S., Jiménez-Murcia, S., Johnson, C., Kaplan, A. S., Kaye, W. H., Keel, P. K., Kennedy, J. L., Kim, M., Klump, K. L., Levey, D. F., Li, D., Liao, S. C., Lieb, K., Lilenfeld, L., Marshall, C. R., Mitchell, J. E., Okazaki, S., Otsuka, I., Pinto, D., Powers, A., Ramoz, N., Ripke, S., Roepke, S., Rozanov, V., Scherer, S. W., Schmahl, C., Sokolowski, M., Starnawska, A., Strober, M., Su, M. H., Thornton, L. M., Treasure, J., Ware, E. B., Watson, H. J., Witt, S. H., Blake Woodside, D., Yilmaz, Z., Zillich, L., Adolfsson, R., Agartz, I., Alda, M., Alfredsson, L., Appadurai, V., Artigas, M. S., Van Der Auwera, S., Helena Azevedo, M., Bass, N., Bau, C. H. D., Baune, B. T., Bellivier, F., Berger, K., Biernacka, J. M., Bigdeli, T. B., Binder, E. B., Boehnke, M., Boks, M. P., Braff, D. L., Bryant, R., Budde, M., Byrne, E. M., Cahn, W., Castelao, E., Cervilla, J. A., Chaumette, B., Corvin, A., Craddock, N., Djurovic, S., Foo, J. C., Forstner, A. J., Frye, M., Gatt, J. M., Giegling, I., Grabe, H. J., Green, M. J., Grevet, E. H., Grigoroiu-Serbanescu, M., Gutierrez, B., Guzman-Parra, J., Hamshere, M. L., Hartmann, A. M., Hauser, J., Heilmann-Heimbach, S., Hoffmann, P., Ising, M., Jones, I., Jones, L. A., Jonsson, L., Kahn, R. S., Kelsoe, J. R., Kendler, K. S., Kloiber, S., Koenen, K. C., Kogevinas, M., Krebs, M. O., Landén, M., Leboyer, M., Lee, P. H., Levinson, D. F., Liao, C., Lissowska, J., Mayoral, F., McElroy, S. L., McGrath, P., McGuffin, P., McQuillin, A., Mehta, D., Melle, I., Mitchell, P. B., Molina, E., Morken, G., Nievergelt, C., Nöthen, M. M., O'Donovan, M. C., Ophoff, R. A., Owen, M. J., Pato, C., Pato, M. T., Penninx, B. W. J. H., Potash, J. B., Power, R. A., Preisig, M., Quested, D., Ramos-Quiroga, J. A., Reif, A., Ribasés, M., Richarte, V., Rietschel, M., Rivera, M., Roberts, A., Roberts, G., Rouleau, G. A., Rovaris, D. L., Sanders, A. R., Schofield, P. R., Schulze, T. G., Scott, L. J., Serretti, A., Shi, J., Sirignano, L., Sklar, P., Smeland, O. B., Smoller, J. W., Sonuga-Barke, E. J. S., Trzaskowski, M., Tsuang, M. T., Turecki, G., Vilar-Ribó, L., Vincent, J. B., Völzke, H., Walters, J. T. R., Weickert, C. S., Weickert, T. W., Weissman, M. M., Williams, L. M., Wray, N. R., Zai, C. C., Agerbo, E., Børglum, A. D., Breen, G., Demontis, D., Erlangsen, A., Gelernter, J., Glatt, S. J., Hougaard, D. M., Hwu, H. G., Kuo, P. H., Lewis, C. M., Li, Q. S., Liu, C. M., Martin, N. G., McIntosh, A. M., Medland, S. E., Mors, O., Nordentoft, Merete, Olsen, C. M., Porteous, D., Smith, D. J., Stahl, E. A., Stein, M. B., Wasserman, D., Werge, Thomas, Whiteman, D. C., Willour, V., Coon, H., Beckham, J. C., Kimbrel, N. A. & Ruderfer, D. M., 2023, In: American Journal of Psychiatry. 180, 10, p. 723-738 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic and epidemiological analyses of infection load and its relationship with psychiatric disorders

Nudel, R., Hougaard, D. M., Werge, Thomas & Benros, Michael Eriksen, 2023, In: Epidemiology and Infection. 151, 11 p., e93.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic correlates of vitamin D-binding protein and 25-hydroxyvitamin D in neonatal dried blood spots

Albiñana, C., Zhu, Z., Borbye-Lorenzen, N., Boelt, S. G., Cohen, A. S., Skogstrand, K., Wray, N. R., Revez, J. A., Privé, F., Petersen, L. V., Bulik, C. M., Plana-Ripoll, O., Musliner, K. L., Agerbo, E., Børglum, A. D., Hougaard, D. M., Nordentoft, M., Werge, T., Mortensen, P. B., Vilhjálmsson, B. J. & 1 others, McGrath, J. J., 2023, In: Nature Communications. 14, 16 p., 852.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic liability to posttraumatic stress disorder and its association with postpartum depression

Bang Madsen, K., Liu, X., Albiñana, C., Jóhann Vilhjálmsson, B., Agerbo, E., Mortensen, P. B., Hougaard, D. M., Nordentoft, Merete, Werge, Thomas, Mors, O., Børglum, A. D. & Munk-Olsen, T., 2023, In: Psychological Medicine. 53, 11, p. 1-8 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains: [Inkl. Correction]

Demontis, D., Walters, G. B., Athanasiadis, G., Walters, R., Therrien, K., Nielsen, T. T., Farajzadeh, L., Voloudakis, G., Bendl, J., Zeng, B., Zhang, W., Grove, J., Als, T. D., Duan, J., Satterstrom, F. K., Bybjerg-Grauholm, J., Bækved-Hansen, M., Gudmundsson, O. O., Magnusson, S. H., Baldursson, G. & 32 others, Davidsdottir, K., Haraldsdottir, G. S., Agerbo, E., Hoffman, G. E., Dalsgaard, Søren, Martin, J., Ribasés, M., Boomsma, D. I., Soler Artigas, M., Roth Mota, N., Howrigan, D., Medland, S. E., Zayats, T., Rajagopal, V. M., Havdahl, A., Doyle, A., Reif, A., Thapar, A., Cormand, B., Liao, C., Burton, C., Bau, C. H. D., Rovaris, D. L., Sonuga-Barke, E., Corfield, E., Grevet, E. H., Larsson, H., Gizer, I. R., Nordentoft, Merete, Werge, Thomas, ADHD Working Group of the Psychiatric Genomics Consortium, A. W. G. O. T. P. G. C. & iPSYCH-Broad Consortium, I. C., 2023, In: Nature Genetics. 55, p. 198–208 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth

Beaumont, R. N., Flatley, C., Vaudel, M., Wu, X., Chen, J., Moen, G. H., Skotte, L., Helgeland, Ø., Solé-Navais, P., Banasik, K., Albiñana, C., Ronkainen, J., Fadista, J., Stinson, S. E., Trajanoska, K., Wang, C. A., Westergaard, D., Srinivasan, S., Sánchez-Soriano, C., Bilbao, J. R. & 68 others, Allard, C., Groleau, M., Kuulasmaa, T., Leirer, D. J., White, F., Jacques, P. É., Cheng, H., Hao, K., Andreassen, O. A., Åsvold, B. O., Atalay, M., Bhatta, L., Bouchard, L., Brumpton, B. M., Brunak, Søren, Bybjerg-Grauholm, J., Ebbing, C., Elliott, P., pjx571, pjx571, Erikstrup, C., Estarlich, M., Franks, S., Gaillard, R., Geller, F., Grove, J., Hougaard, D. M., Kajantie, E., Morgen, C. S., Nohr, E. A., Nyegaard, Mette, Palmer, C. N. A., Pedersen, Ole Birger Vesterager, Rivadeneira, F., Sebert, S., Shields, B. M., Stoltenberg, C., Surakka, I., Thørner, L. W., Ullum, H., Vaarasmaki, M., Vilhjalmsson, B. J., Willer, C. J., Lakka, T. A., Gybel-Brask, D., Bustamante, M., Hansen, Torben, Pearson, E. R., Reynolds, R. M., Ostrowski, Sisse Rye, Pennell, C. E., Jaddoe, V. W. V., Felix, J. F., Hattersley, A. T., Melbye, M., Lawlor, D. A., Hveem, K., Werge, Thomas, Nielsen, Henriette Svarre, Magnus, P., Evans, D. M., Jacobsson, B., Järvelin, M. R., Zhang, G., Hivert, M. F., Johansson, S., Freathy, R. M., Feenstra, B. & Njølstad, P. R., 2023, In: Nature Genetics. 55, 11, p. 1807-1819 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity

Rajagopal, V. M., Ganna, A., Coleman, J. R. I., Allegrini, A., Voloudakis, G., Grove, J., Als, T. D., Horsdal, H. T., Petersen, L., Appadurai, V., Schork, A., Buil, A., Bulik, C. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Hougaard, D. M., Mors, O., Nordentoft, M., Werge, T., Mortensen, P. B. & 7 others, Breen, G., Roussos, P., Plomin, R., Agerbo, E., Borglum, A. D., Demontis, D. & iPSYCH-Broad Consortium, I. C., 2023, In: Scientific Reports. 13, 16 p., 429.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide by Environment Interaction Study of Stressful Life Events and Hospital-Treated Depression in the iPSYCH2012 Sample

Suppli, N. P., Andersen, K. K., Agerbo, E., Rajagopal, V. M., Appadurai, V., Coleman, J. R. I., Breen, G., Bybjerg-grauholm, J., Bækvad-hansen, M., Pedersen, C. B., Pedersen, M. G., Thompson, W. K., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., Mors, O. & 3 others, Nordentoft, Merete, Mortensen, P. B. & Musliner, K. L., 2023, In: Biological Psychiatry Global Open Science. 2, 4, p. 400-410 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Interplay of ADHD Polygenic Liability With Birth-Related, Somatic, and Psychosocial Factors in ADHD: A Nationwide Study

Brikell, I., Wimberley, T., Albiñana, C., Vilhjálmsson, B. J., Agerbo, E., Børglum, A. D., Demontis, D., Schork, A. J., LaBianca, S., Werge, Thomas, Hougaard, D. M., Nordentoft, Merete, Mors, O., Mortensen, P. B., Petersen, L. V. & Dalsgaard, S., 2023, In: The American Journal of Psychiatry. 180, 1, p. 73-88 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression

Guintivano, J., Byrne, E. M., Kiewa, J., Yao, S., Bauer, A. E., Aberg, K. A., Adams, M. J., Campbell, A., Campbell, M. L., Choi, K. W., Corfield, E. C., Havdahl, A., Hucks, D., Koen, N., Lu, Y., Mægbæk, M. L., Mullaert, J., Peterson, R. E., Raffield, L. M., Sallis, H. M. & 59 others, Sealock, J. M., Walker, A., Watson, H. J., Xiong, Y., Yang, J. M. K., Anney, R. J. L., Gordon-Smith, K., Hubbard, L., Jones, L. A., Mihaescu, R., Nyegaard, M., Pardiñas, A. F., Perry, A., Saquib, N., Shadyab, A. H., Viktorin, A., Andreassen, O. A., Bigdeli, T. B., Davis, L. K., Dennis, C., Di Florio, A., Dubertret, C., Feng, Y. A., Frey, B. N., Grigoriadis, S., Gloaguen, E., Jones, I., Kennedy, J. L., Krohn, H., Kallak, T. K., Li, Y., Martin, N. G., McIntosh, A. M., Milgrom, J., Munk-Olsen, T., Oberlander, T., Olsen, C. M., Ramoz, N., Reichborn-Kjennerud, T., Blackmore, E. R., Rubinow, D., Skalkidou, A., Smoller, J. W., Stein, D. J., Stowe, Z. N., Taylor, V., Tebeka, S., Tesli, M., Van Lieshout, R. J., van den Oord, E. J. C. G., Vigod, S. N., Werge, Thomas, Westlye, L. T., Whiteman, D. C., Zar, H. J., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., Wray, N., Meltzer-Brody, S. & Sullivan, P., 2023, In: The American Journal of Psychiatry. 180, 12, p. 884-895 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Metabolic signature of the pathogenic 22q11.2 deletion identifies carriers and provides insight into systemic dysregulation

Courraud, J., Russo, F., Themudo, G. E., Laursen, S. S., Ingason, A., Hougaard, D. M., Cohen, A. S., Werge, Thomas & Ernst, M., 2023, In: Translational Psychiatry. 13, 7 p., 391.

Research output: Contribution to journal › Journal article › Research › peer-review

Multi-PGS enhances polygenic prediction by combining 937 polygenic scores

Albiñana, C., Zhu, Z., Schork, A. J., Ingason, A., Aschard, H., Brikell, I., Bulik, C. M., Petersen, L. V., Agerbo, E., Grove, J., Nordentoft, Merete, Hougaard, D. M., Werge, Thomas, Børglum, A. D., Mortensen, P. B., McGrath, J. J., Neale, B. M., Privé, F. & Vilhjálmsson, B. J., 2023, In: Nature Communications. 14, 11 p., 4702.

Research output: Contribution to journal › Journal article › Research › peer-review

Phenotype integration improves power and preserves specificity in biobank-based genetic studies of major depressive disorder

Dahl, A., Thompson, M., An, U., Krebs, M., Appadurai, V., Border, R., Bacanu, S., Werge, Thomas, Flint, J., Schork, A. J., Sankararaman, S., Kendler, K. S. & Cai, N., 2023, In: Nature Genetics. 55, 12, p. 2082-2093

Research output: Contribution to journal › Journal article › Research › peer-review

Polygenic liability, stressful life events and risk for secondary-treated depression in early life: a nationwide register-based case-cohort study

Musliner, K. L., Andersen, K. K., Agerbo, E., Albiñana, C., Vilhjalmsson, B. J., Rajagopal, V. M., Bybjerg-Grauholm, J., Bækved-Hansen, M., Pedersen, C. B., Pedersen, M. G., Munk-Olsen, T., Benros, M. E., Als, T. D., Grove, J., Werge, T., Børglum, A. D., Hougaard, D. M., Mors, O., Nordentoft, M., Mortensen, P. B. & 2 others, Suppli, N. P. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2023, In: Psychological Medicine. 53, p. 217–226 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Postpartum and non-postpartum depression: a population-based matched case-control study comparing polygenic risk scores for severe mental disorders

Munk-Olsen, T., Di Florio, A., Madsen, K. B., Albiñana, C., Mægbæk, M. L., Bergink, V., Frøkjær, Vibe Gedsø, Agerbo, E., Vilhjálmsson, B. J., Werge, Thomas, Nordentoft, Merete, Hougaard, D. M., Børglum, A. D., Mors, O., Mortensen, P. B. & Liu, X., 2023, In: Translational Psychiatry. 13, 1, 7 p., 346.

Research output: Contribution to journal › Journal article › Research › peer-review

Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura

Bjornsdottir, G., Chalmer, M. A., Stefansdottir, L., Skuladottir, A. T., Einarsson, G., Andresdottir, M., Beyter, D., Ferkingstad, E., Gretarsdottir, S., Halldorsson, B. V., Halldorsson, G. H., Helgadottir, A., Helgason, H., Hjorleifsson Eldjarn, G., Jonasdottir, A., Jonasdottir, A., Jonsdottir, I., Knowlton, K. U., Nadauld, L. D., Lund, S. H. & 30 others, Magnusson, O. T., Melsted, P., Moore, K. H. S., Oddsson, A., Olason, P. I., Sigurdsson, A., Banasik, Karina, Brunak, Søren, Didriksen, Maria, Kogelman, L. J. A., Nielsen, K. R., Sørensen, E., Pedersen, Ole Birger Vesterager, Ullum, H., Bay, J., Burgdorf, Kristoffer Sølvsten, Dowsett, J., Hjalgrim, Henrik, Jacobsen, R. L., Louloudis, Ioannis, Lundgaard, Agnete Troen, Mikkelsen, Christina, Nyegaard, Mette, Henriksen, Alexander Pil, Werge, Thomas, Westergaard, David, Olesen, Jes, Ostrowski, Sisse Rye, Hansen, Thomas Folkmann & DBDS Genetic Consortium, D. G. C., 2023, In: Nature Genetics. 55, 11, p. 1843-1853

Research output: Contribution to journal › Journal article › Research › peer-review

School performance and genetic propensities for educational attainment and depression in the etiology of self-harm: a Danish population-based study

Sørensen, H. J., Antonsen, S., Benros, Michael Eriksen, Erlangsen, A., Albiñana, C., Nordentoft, Merete, Børglum, A. D., Mors, O., Werge, Thomas, Mortensen, P. B., Hougaard, D., Webb, R. T. & Agerbo, E., 2023, In: Nordic Journal of Psychiatry. 77, 2, p. 179-187 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The correlates of neonatal complement component 3 and 4 protein concentrations with a focus on psychiatric and autoimmune disorders

Borbye-Lorenzen, N., Zhu, Z., Agerbo, E., Albiñana, C., Benros, M. E., Bian, B., Børglum, A. D., Bulik, C. M., Debost, J-C. P. G., Grove, J., Hougaard, D. M., McRae, A. F., Mors, O., Mortensen, P. B., Musliner, K. L., Nordentoft, M., Petersen, L. V., Privé, F., Sidorenko, J., Skogstrand, K. & 4 others, Werge, Thomas, Wray, N. R., Vilhjálmsson, B. J. & McGrath, J. J., 2023, In: Cell Genomics. 3, 12, 23 p., 100457.

Research output: Contribution to journal › Journal article › Research › peer-review

The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement

Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Baekvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, Merete, Borglum, A. D., Werge, Thomas, Melbye, M., Hougaard, D. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Christiansen, M., 2023, In: Brain Communications. 5, 1, 14 p., fcad004.

Research output: Contribution to journal › Journal article › Research › peer-review

The genetic history of Scandinavia from the Roman Iron Age to the present

Rodríguez-Varela, R., Moore, K. H. S., Ebenesersdóttir, S. S., Kilinc, G. M., Kjellström, A., Papmehl-Dufay, L., Alfsdotter, C., Berglund, B., Alrawi, L., Kashuba, N., Sobrado, V., Lagerholm, V. K., Gilbert, E., Cavalleri, G. L., Hovig, E., Kockum, I., Olsson, T., Alfredsson, L., Hansen, T. F., Werge, T. & 24 others, Munters, A. R., Bernhardsson, C., Skar, B., Christophersen, A., Turner-Walker, G., Gopalakrishnan, Shyam, Daskalaki, E., Omrak, A., Pérez-Ramallo, P., Skoglund, P., Girdland-Flink, L., Gunnarsson, F., Hedenstierna-Jonson, C., Gilbert, M Thomas P, Lidén, K., Jakobsson, M., Einarsson, L., Victor, H., Krzewińska, M., Zachrisson, T., Storå, J., Stefánsson, K., Helgason, A. & Götherström, A., 2023, In: Cell. 186, 1, p. 32-46.e19

Research output: Contribution to journal › Journal article › Research › peer-review

Maternal pregnancy-related infections and autism spectrum disorder—the genetic perspective

Nudel, R., Thompson, W. K., Børglum, A. D., Hougaard, D. M., Mortensen, P. B., Werge, Thomas, Nordentoft, Merete & Benros, Michael Eriksen, Dec 2022, In: Translational Psychiatry. 12, 1, 9 p., 334.

Research output: Contribution to journal › Journal article › Research › peer-review

Is the CYP2D6 Genotype Associated with Antipsychotic-Induced Weight Gain?

Jürgens, Gesche, Kaas-Hansen, Benjamin Skov, Nordentoft, Merete, Werge, Thomas & Andersen, Stig Ejdrup, Oct 2022, In: Journal of Personalized Medicine. 12, 10, 12 p., 1728.

Research output: Contribution to journal › Journal article › Research › peer-review

Elucidating the relationship between migraine risk and brain structure using genetic data

International Headache Genetics Consortium, I. H. G. C., 1 Sep 2022, In: Brain. 145, 9, p. 3214-3224 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Enhancing discovery of genetic variants for PTSD through integration of quantitative phenotypes and trauma exposure information

Maihofer, A. X., Choi, K. W., Coleman, J. R. I., Daskalakis, N. P., Denckla, C. A., Ketema, E., Morey, R. A., Polimanti, R., Ratanatharathorn, A., Torres, K., Wingo, A. P., Zai, C. C., Aiello, A. E., Almli, L. M., Amstadter, A. B., Andersen, S. B., Andreassen, O. A., Arbisi, P. A., Ashley-Koch, A. E., Austin, S. B. & 161 others, Avdibegovic, E., Borglum, A. D., Babic, D., Bμkvad-Hansen, M., Baker, D. G., Beckham, J. C., Bierut, L. J., Bisson, J. I., Boks, M. P., Bolger, E. A., Bradley, B., Brashear, M., Breen, G., Bryant, R. A., Bustamante, A. C., Bybjerg-Grauholm, J., Calabrese, J. R., Caldas-de-Almeida, J. M., Chen, C., Dale, A. M., Dalvie, S., Deckert, J., Delahanty, D. L., Dennis, M. F., Disner, S. G., Domschke, K., Duncan, L. E., Kulenovic, A. D., Erbes, C. R., Evans, A., Farrer, L. A., Feeny, N. C., Flory, J. D., Forbes, D., Franz, C. E., Galea, S., Garrett, M. E., Gautam, A., Gelaye, B., Gelernter, J., Geuze, E., Gillespie, C. F., Goci, A., Gordon, S. D., Guffanti, G., Hammamieh, R., Hauser, M. A., Heath, A. C., Hemmings, S. M. J., Hougaard, D. M., Jakovljevic, M., Jett, M., Johnson, E. O., Jones, I., Jovanovic, T., Qin, X., Karstoft, Karen-Inge, Kaufman, M. L., Kessler, R. C., Khan, A., Kimbrel, N. A., King, A. P., Koen, N., Kranzler, H. R., Kremen, W. S., Lawford, B. R., Lebois, L. A. M., Lewis, C., Liberzon, I., Linnstaedt, S. D., Logue, M. W., Lori, A., Lugonja, B., Luykx, J. J., Lyons, M. J., Maples-Keller, J. L., Marmar, C., Martin, N. G., Maurer, D., Mavissakalian, M. R., McFarlane, A., McGlinchey, R. E., McLaughlin, K. A., McLean, S. A., Mehta, D., Mellor, R., Michopoulos, V., Milberg, W., Miller, M. W., Morris, C. P., Mors, O., Mortensen, P. B., Nelson, E. C., Nordentoft, Merete, Norman, S. B., O'Donnell, M., Orcutt, H. K., Panizzon, M. S., Peters, E. S., Peterson, A. L., Peverill, M., Pietrzak, R. H., Polusny, M. A., Rice, J. P., Risbrough, V. B., Roberts, A. L., Rothbaum, A. O., Rothbaum, B. O., Roy-Byrne, P., Ruggiero, K. J., Rung, A., Rutten, B. P. F., Saccone, N. L., Sanchez, S. E., Schijven, D., Seedat, S., Seligowski, A. V., Seng, J. S., Sheerin, C. M., Silove, D., Smith, A. K., Smoller, J. W., Sponheim, S. R., Stein, D. J., Stevens, J. S., Teicher, M. H., Thompson, W. K., Trapido, E., Uddin, M., Ursano, R. J., Luella van den Heuvel, L., Van Hooff, M., Vermetten, E., Vinkers, C., Voisey, J., Wang, Y., Wang, Z., Werge, Thomas, Williams, M. A., Williamson, D. E., Winternitz, S., Wolf, C., Wolf, E. J., Yehuda, R., Young, K. A., Young, R. M., Zhao, H., Zoellner, L. A., Haas, M., Lasseter, H., Provost, A. C., Salem, R. M., Sebat, J., Shaffer, R. A., Wu, T., Ripke, S., Daly, M. J., Ressler, K. J., Koenen, K. C., Stein, M. B. & Nievergelt, C. M., 1 Apr 2022, In: Biological Psychiatry. 91, 7, p. 626-636 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Family disadvantage, gender, and the returns to genetic human capital

Ronda, V., Agerbo, E., Bleses, D., Mortensen, P. B., Borglum, A., Mors, O., Rosholm, M., Hougaard, D. M., Nordentoft, Merete & Werge, Thomas, Apr 2022, In: Scandinavian Journal of Economics. 124, 2, p. 550-578 29 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy

Athanasiadis, G., Meijsen, J. J., Helenius, D., Schork, A. J., Ingason, A., Thompson, W. K., Geschwind, D. H., Werge, Thomas & Buil, A., 2022, In: PNAS. 119, 6, 9 p., e2118688119.

Research output: Contribution to journal › Journal article › Research › peer-review

A family-based study of genetic and epigenetic effects across multiple neurocognitive, motor, social-cognitive and social-behavioral functions

Nudel, R., Zetterberg, R., Hemager, N., Christiani, C. A. J., Ohland, J., Burton, B. K., Greve, A. N., Spang, K. S., Ellersgaard, D., Gantriis, D. L., Bybjerg-Grauholm, J., Plessen, K. J., Jepsen, J. R. M., Thorup, Anne, Werge, Thomas, Mors, O. & Nordentoft, Merete, 2022, In: Behavioral and Brain Functions. 18, 14.

Research output: Contribution to journal › Journal article › Research › peer-review

A saturated map of common genetic variants associated with human height

Yengo, L., Vedantam, S., Marouli, E., Sidorenko, J., Bartell, E., Sakaue, S., Graff, M., Eliasen, A. U., Jiang, Y., Raghavan, S., Miao, J., Arias, J. D., Graham, S. E., Mukamel, R. E., Spracklen, C. N., Yin, X., Chen, S-H., Ferreira, T., Highland, H. H., Ji, Y. & 37 others, Karaderi, Tugce, Lin, K., Lull, K., Malden, D. E., Lepola, Mette Andersen, Appadurai, V., Bork-Jensen, J., Burgdorf, Kristoffer Sølvsten, Hansen, Thomas Folkmann, Jonsson, Anna Elisabet, Jorgensen, T., Liu, J., Møllehave, Line Tang, Smit, Roelof Adriaan Johan, Zhao, J., Bisgaard, H., Bønnelykke, Klaus, Dantoft, T. M., Grarup, Niels, Hansen, Torben, Jackson, R. D., Karpe, F., Kovacs, P., Lind, L., Linneberg, Allan René, Pedersen, Oluf Borbye, Werge, Thomas, Sun, Y., Loos, Ruth, Winkler, T. W., 23andMe Res Team, 2. R. T., VA Million Vet Program, V. M. V. P., DiscovEHR DiscovEHR MyCode Communi, D. D. M. C., eEMERGE Elect Med Records Genomics, E. E. M. R. G., LifeLines Cohort Study, L. C. S., PRACTICAL consortium, P. C. & Understanding Soc Sci Grp, U. S. S. G., 2022, In: Nature. 610, p. 704–712

Research output: Contribution to journal › Journal article › Research › peer-review

Accounting for age of onset and family history improves power in genome-wide association studies

Pedersen, E. M., Agerbo, E., Plana-Ripoll, O., Grove, J., Dreier, J. W., Musliner, K. L., Bækvad-Hansen, M., Athanasiadis, G., Schork, A., Bybjerg-Grauholm, J., Hougaard, D. M., Werge, T., Nordentoft, M., Mors, O., Dalsgaard, S., Christensen, J., Børglum, A. D., Mortensen, P. B., McGrath, J. J., Privé, F. & 1 others, Vilhjálmsson, B. J., 2022, In: American Journal of Human Genetics. 109, 3, p. 417-432 16 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Accumulation of Disadvantages Across Multiple Domains Amongst Subgroups of Children of Parents with Schizophrenia or Bipolar Disorder: Clustering Data from the Danish High Risk and Resilience Study VIA 7

Krantz, M. F., Ellersgaard, D., Andersen, K. K., Hemager, N., Christiani, C., Spang, K. S., Burton, B. K., Gregersen, M., Søndergaard, A., Greve, A., Gantriis, D. L., Ohland, J., Mortensen, P. B., Werge, T., Nudel, R., Wang, Y., Hougaard, D. M., Plessen, K. J., Bliksted, V., Jepsen, J. R. M. & 3 others, Thorup, Anne, Mors, O. & Nordentoft, Merete, 2022, In: Schizophrenia Bulletin Open. 3, 1, 16 p., sgac010.

Research output: Contribution to journal › Journal article › Research › peer-review

Accurate and Effective Detection of Recurrent Copy Number Variants in Large SNP Genotype Datasets

Montalbano, S., Sánchez, X. C., Vaez, M., Helenius, D., Werge, Thomas & Ingason, A., 2022, In: Current Protocols. 2, 12, 21 p., e621.

Research output: Contribution to journal › Journal article › Research › peer-review

Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations

Unnarsdóttir, A. B., Lovik, A., Fawns-Ritchie, C., Ask, H., Kõiv, K., Hagen, K., Didriksen, M., Christoffersen, L. A. N., Garðarsson, A. B., McIntosh, A., Kähler, A. K., Campbell, A., Hauksdóttir, A., Erikstrup, C., Mikkelsen, D. H., Altschul, D., Thordardottir, E. B., Frans, E. M., Kvale, G., Tómasson, G. & 32 others, Kariis, H. M., Jónsdóttir, H. L., Rúnarsdóttir, H., Magnúsdóttir, I., Eid, J., Jakobsdóttir, J., Nielsen, K. R., Kaspersen, K. A., Milani, L., Trogstad, L. S., Yi, L., Bruun, M. T., Sullivan, P. F., Magnus, P. M., Shen, Q., Nesvåg, R., Brandlistuen, R. E., Mägi, R., Ostrowski, Sisse Rye, Løkhammer, S., Solem, S., Reichborn-Kjennerud, T., Hansen, Thomas Folkmann, Werge, Thomas, Aspelund, T., Porteous, D. J., Fang, F., Lehto, K., Andreassen, O. A., Pedersen, Ole Birger Vesterager, Hellard, S. L. & Valdimarsdóttir, U. A., 2022, In: International Journal of Epidemiology. 51, 3, p. e108–e122 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Common Genetic Variation and Age of Onset of Anorexia Nervosa

Watson, H. J., Thornton, L. M., Yilmaz, Z., Baker, J. H., Coleman, J. R. I., Adan, R. A. H., Alfredsson, L., Andreassen, O. A., Ask, H., Berrettini, W. H., Boehnke, M., Boehm, I., Boni, C., Buehren, K., Bulant, J., Burghardt, R., Chang, X., Cichon, S., Cone, R. D., Courtet, P. & 157 others, Crow, S., Crowley, J. J., Danner, U. N., de Zwaan, M., Dedoussis, G., DeSocio, J. E., Dick, D. M., Dikeos, D., Dina, C., Djurovic, S., Dmitrzak-Weglarz, M., Docampo-Martinez, E., Duriez, P., Egberts, K., Ehrlich, S., Eriksson, J. G., Escaramís, G., Esko, T., Estivill, X., Farmer, A., Fernández-Aranda, F., Fichter, M. M., Föcker, M., Foretova, L., Forstner, A. J., Frei, O., Gallinger, S., Giegling, I., Giuranna, J., Gonidakis, F., Gorwood, P., Gratacòs, M., Guillaume, S., Guo, Y., Hakonarson, H., Hauser, J., Havdahl, A., Hebebrand, J., Helder, S. G., Herms, S., Herpertz-Dahlmann, B., Herzog, W., Hinney, A., Hübel, C., Hudson, J. I., Imgart, H., Jamain, S., Janout, V., Jiménez-Murcia, S., Jones, I. R., Julià, A., Kalsi, G., Kaminská, D., Kaprio, J., Karhunen, L., Kas, M. J. H., Keel, P. K., Kennedy, J. L., Keski-Rahkonen, A., Kiezebrink, K., Klareskog, L., Klump, K. L., Knudsen, G. P. S., La Via, M. C., Le Hellard, S., Leboyer, M., Li, D., Lilenfeld, L., Lin, B., Lissowska, J., Luykx, J., Magistretti, P., Maj, M., Marsal, S., Marshall, C. R., Mattingsdal, M., Meulenbelt, I., Micali, Nadia, Mitchell, K. S., Monteleone, A. M., Monteleone, P., Myers, R., Navratilova, M., Ntalla, I., O'Toole, J. K., Ophoff, R. A., Padyukov, L., Pantel, J., Papežová, H., Pinto, D., Raevuori, A., Ramoz, N., Reichborn-Kjennerud, T., Ricca, V., Ripatti, S., Ripke, S., Ritschel, F., Roberts, M., Rotondo, A., Rujescu, D., Rybakowski, F., Scherag, A., Scherer, S. W., Schmidt, U., Scott, L. J., Seitz, J., Silén, Y., Šlachtová, L., Slagboom, P. E., Slof-Op ‘t Landt, M. C. T., Slopien, A., Sorbi, S., Świątkowska, B., Tortorella, A., Tozzi, F., Treasure, J., Tsitsika, A., Tyszkiewicz-Nwafor, M., Tziouvas, K., van Elburg, A. A., van Furth, E. F., Walton, E., Widen, E., Zerwas, S., Zipfel, S., Bergen, A. W., Boden, J. M., Brandt, H., Crawford, S., Halmi, K. A., Horwood, L. J., Johnson, C., Kaplan, A. S., Kaye, W. H., Mitchell, J. E., Olsen, C. M., Pearson, J. F., Pedersen, N. L., Strober, M., Werge, Thomas, Whiteman, D. C., Woodside, D. B., Gordon, S., Maguire, S., Larsen, J. T., Parker, R., Petersen, L. V., Jordan, J., Kennedy, M., Wade, T. D., Birgegård, A., Lichtenstein, P., Landén, M., Martin, N. G., Mortensen, P. B., Breen, G. & Bulik, C. M., 2022, In: Biological Psychiatry Global Open Science. 2, 4, p. 368-378 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Comparing Copy Number Variations in a Danish Case Cohort of Individuals with Psychiatric Disorders

Calle Sánchez, X., Helenius, D., Bybjerg-Grauholm, J., Pedersen, C., Hougaard, D. M., Børglum, A. D., Nordentoft, Merete, Mors, O., Mortensen, P. B., Geschwind, D. H., Montalbano, S., Raznahan, A., Thompson, W. K., Ingason, A. & Werge, Thomas, 2022, In: JAMA Psychiatry. 79, 1, p. 59-69

Research output: Contribution to journal › Journal article › Research › peer-review

Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

Fadista, J., Skotte, L., Karjalainen, J., Abner, E., Sørensen, E., Ullum, H., Werge, Thomas, Esko, T., Milani, L., Palotie, A., Daly, M., Melbye, M., Feenstra, B., Geller, F., IPSYCH Grp, I. G. & FinnGen Consortium, F. C., 2022, In: Nature Communications. 13, 11 p., 3200.

Research output: Contribution to journal › Journal article › Research › peer-review

Cross-trait assortative mating is widespread and inflates genetic correlation estimates

Border, R., Athanasiadis, G., Buil Demur, Alfonso Alberto, Schork, A. J., Cai, N., Young, A. I., Werge, Thomas, Flint, J., Kendler, K. S., Sankararaman, S., Dahl, A. W. & Zaitlen, N. A., 2022, In: Science. 378, 6621, p. 754-761 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Current advancements of modelling schizophrenia using patient-derived induced pluripotent stem cells

Dubonyte, Ugne, Asenjo-Martinez, A., Werge, Thomas, Lage, K. & Kirkeby, Agnete, 2022, In: Acta Neuropathologica Communications. 10, 1, 20 p., 183.

Research output: Contribution to journal › Review › Research › peer-review

Deep learning-based integration of genetics with registry data for stratification of schizophrenia and depression

Allesøe, R. L., Nudel, R., Thompson, W. K., Wang, Y., Nordentoft, Merete, Børglum, A. D., Hougaard, D. M., Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2022, In: Science Advances. 8, 26, eabi7293.

Research output: Contribution to journal › Journal article › Research › peer-review

Differences in the genetic architecture of common and rare variants in childhood, persistent and late-diagnosed attention-deficit hyperactivity disorder

Rajagopal, V. M., Duan, J., Vilar-Ribó, L., Grove, J., Zayats, T., Ramos-Quiroga, J. A., Satterstrom, F. K., Artigas, M. S., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Als, T. D., Rosengren, A., Daly, M. J., Neale, B. M., Nordentoft, M., Werge, T., Mors, O., Hougaard, D. M., Mortensen, P. B., Ribasés, M. & 2 others, Børglum, A. D. & Demontis, D., 2022, In: Nature Genetics. 54, 8, p. 1117-1124 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

Mullins, N., Kang, J. E., Campos, A. I., Coleman, J. R. I., Edwards, A. C., Galfalvy, H., Levey, D. F., Lori, A., Shabalin, A., Starnawska, A., Su, M. H., Watson, H. J., Adams, M., Awasthi, S., Gandal, M., Hafferty, J. D., Hishimoto, A., Kim, M., Okazaki, S., Otsuka, I. & 36 others, Ripke, S., Ware, E. B., Bergen, A. W., Berrettini, W. H., Bohus, M., Brandt, H., Chang, X., Chen, W. J., Chen, H. C., Crawford, S., Crow, S., DiBlasi, E., Duriez, P., Fernández-Aranda, F., Fichter, M. M., Gallinger, S., Glatt, S. J., Gorwood, P., Guo, Y., Hakonarson, H., Halmi, K. A., Hwu, H. G., Jain, S., Li, D., Røpke, S., Appadurai, V., Jonsson, L., Schofield, Peter, Nordentoft, Merete, Werge, Thomas, VA Million Veteran Program, V. M. V. P., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C., Eating Disorders Working Group of the Psychiatric Genomics Consortium, E. D. W. G. O. T. P. G. C., German Borderline Genomics Consortium, G. B. G. C. & MVP Suicide Exemplar Workgroup, M. S. E. W., 2022, In: Biological Psychiatry. 91, 3, p. 313-327 15 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Evaluating the interrelations between the autism polygenic score and psychiatric family history in risk for autism

Schendel, D., Munk Laursen, T., Albiñana, C., Vilhjalmsson, B., Ladd-Acosta, C., Fallin, M. D., Benke, K., Lee, B., Grove, J., Kalkbrenner, A., Ejlskov, L., Hougaard, D., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Børglum, A. D., Werge, Thomas, Nordentoft, Merete, Mortensen, P. B. & Agerbo, E., 2022, In: Autism Research. 15, 1, p. 171-182

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic and psychosocial influence on the association between early childhood infections and later psychiatric disorders

Debost, J. P. G., Thorsteinsson, E., Trabjerg, B., Benros, Michael Eriksen, Albiñana, C., Vilhjalmsson, B. J., Børglum, A., Mors, O., Werge, Thomas, Mortensen, P. B., Agerbo, E. & Vogdrup, L., 2022, In: Acta Psychiatrica Scandinavica. 146, 5, p. 406-419 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic assortative mating for schizophrenia and bipolar disorder

Jefsen, O. H., Nudel, R., Wang, Y., Bybjerg-Grauholm, J., Hemager, N., Christiani, C. A. J., Burton, B. K., Spang, K. S., Ellersgaard, D., Gantriis, D. L., Plessen, K. J., Jepsen, J. R. M., Thorup, Anne, Werge, Thomas, Nordentoft, Merete, Mors, O. & Greve, A. N., 2022, In: European Psychiatry. 65, 1, 7 p., e53.

Research output: Contribution to journal › Journal article › Research › peer-review

Genetic correlates of phenotypic heterogeneity in autism

Warrier, V., Zhang, X., Reed, P., Havdahl, A., Moore, T. M., Cliquet, F., Leblond, C. S., Rolland, T., Rosengren, A., Caceres, A. S. J., Hayward, H., Crawley, D., Faulkner, J., Sabet, J., Ellis, C., Oakley, B., Loth, E., Charman, T., Murphy, D., Holt, R. & 33 others, Waldman, J., Upadhyay, J., Gunby, N., Lai, M. C., Renouf, G., Ruigrok, A., Taylor, E., Ziauddeen, H., Deakin, J., di Bruttopilo, S. A., van Dijk, S., Rijks, Y., Koops, T., Douma, M., Spaan, A., Selten, I., Steffers, M., van Themaat, A. V. L., Bast, N., Baumeister, S., O’Dwyer, L., Bours, C., Rausch, A., von Rhein, D., Cornelissen, I., de Bruin, Y., Graauwmans, M., Kostrzewa, E., Werge, Thomas, Nordentoft, Merete, EU-AIMS LEAP, E. L., iPSYCH-Autism Working Group, I. W. G. & Spectrum 10K and APEX Consortia, S. 1. A. A. C., 2022, In: Nature Genetics. 54, 9, p. 1293-1304 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study of febrile seizures implicates fever response and neuronal excitability genes

Skotte, L., Fadista, J., Bybjerg-Grauholm, J., Appadurai, V., Hildebrand, M. S., Hansen, T. F., Banasik, K., Grove, J., Albiñana, C., Geller, F., Bjurström, C. F., Vilhjálmsson, B. J., Coleman, M., Damiano, J. A., Burgess, R., Scheffer, I. E., Pedersen, O. B. V., Erikstrup, C., Westergaard, D., Nielsen, K. R. & 19 others, Sørensen, E., Bruun, M. T., Liu, X., Hjalgrim, Henrik, Pers, Tune H, Mortensen, P. B., Mors, O., Nordentoft, Merete, Dreier, J. W., Børglum, A. D., Christensen, J., Hougaard, D. M., Buil, A., Hviid, Anders Peter, Melbye, M., Ullum, H., Berkovic, S. F., Werge, Thomas & Feenstra, B., 2022, In: Brain. 145, 2, p. 555–568

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB

Eliasen, A. U., Pedersen, C. E. T., Rasmussen, M. A., Wang, N., Soverini, M., Fritz, A., Stokholm, J., Chawes, B. L., Morin, A., Bork-Jensen, J., Grarup, N., Pedersen, O., Hansen, T., Linneberg, A., Mortensen, P. B., Hougaard, D. M., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Mors, O., Nordentoft, M. & 14 others, Børglum, A. D., Werge, Thomas, Agerbo, E., Söderhall, C., Altman, M. C., Thysen, A. H., McKennan, C. G., Brix, Susanne, Gern, J. E., Ober, C., Ahluwalia, Tarun Veer Singh, Bisgaard, H., Pedersen, A. G. & Bønnelykke, Klaus, 2022, In: Journal of Allergy and Clinical Immunology. 150, 3, p. 622-630

Research output: Contribution to journal › Journal article › Research › peer-review

Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups

Mattheisen, M., Grove, J., Als, T. D., Martin, J., Voloudakis, G., Meier, S., Demontis, D., Bendl, J., Walters, R., Carey, C. E., Rosengren, A., Strom, N. I., Hauberg, M. E., Zeng, B., Hoffman, G., Zhang, W., Bybjerg-Grauholm, J., Bækvad-Hansen, M., Agerbo, E., Cormand, B. & 14 others, Nordentoft, Merete, Werge, Thomas, Mors, O., Hougaard, D. M., Buxbaum, J. D., Faraone, S. V., Franke, B., Dalsgaard, Søren, Mortensen, P. B., Robinson, E. B., Roussos, P., Neale, B. M., Daly, M. J. & Børglum, A. D., 2022, In: Nature Genetics. 54, p. 1470–1478

Research output: Contribution to journal › Journal article › Research › peer-review

Infection Polygenic Factors Account for a Small Proportion of the Relationship Between Infections and Mental Disorders

Shorter, J. R., Meijsen, J., Nudel, R., Krebs, M., Gådin, J., Mikkelsen, D. H., Nogueira Avelar e Silva, R., Benros, Michael Eriksen, Thompson, W. K., Ingason, A. & Werge, Thomas, 2022, In: Biological Psychiatry. 92, 4, p. 283-290

Research output: Contribution to journal › Journal article › Research › peer-review

Life-time Actionable Pharmacogenetic Drug Use: A Population-based Cohort Study in 86 040 Young People with and without Mental Disorders in Denmark

Lunenburg, C. A. T. C., Ishtiak-Ahmed, K., Werge, Thomas & Gasse, C., 2022, In: Pharmacopsychiatry. 55, 2, p. 95-107

Research output: Contribution to journal › Journal article › Research › peer-review

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C. Y., Dennison, C. A., Hall, L. S., Lam, M., Watanabe, K., Frei, O., Ge, T., Harwood, J. C., Koopmans, F., Magnusson, S., Richards, A. L., Sidorenko, J., Wu, Y. & 35 others, Zeng, J., Grove, J., Kim, M., Li, Z., Voloudakis, G., Zhang, W., Adams, M., Agartz, I., Atkinson, E. G., Agerbo, E., Al Eissa, M., Albus, M., Alexander, M., Alizadeh, B. Z., Alptekin, K., Als, T. D., Amin, F., Arolt, V., Arrojo, M., Athanasiu, L., Azevedo, M. H., Bacanu, S. A., Bass, N. J., Begemann, M., Green, M. F., McGrath, J. J., Pantelis, C., Chen, W. J., Nordentoft, Merete, Werge, Thomas, Indonesia Schizophrenia Consortium, I. S. C., PsychENCODE, P., Psychosis Endophenotypes International Consortium, P. E. I. C., SynGO Consortium, S. C. & Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., 2022, In: Nature. 604, 7906, p. 502-508 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Prevalence of major depressive disorder in 51,658 otherwise healthy adult Danes: Sex differences in symptomatology and prediction of future anti-depressive medication

Mikkelsen, Christina, Larsen, M. A. H., Sørensen, E., Hansen, Thomas Folkmann, Mikkelsen, S., Erikstrup, C., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Kessing, Lars Vedel, Werge, Thomas, Ullum, H., Ostrowski, Sisse Rye, Pedersen, Ole Birger Vesterager, Thørner, L. W. & Didriksen, Maria, 2022, In: Psychiatry Research. 318, 7 p., 114944.

Research output: Contribution to journal › Journal article › Research › peer-review

Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology

Bjornsdottir, G., Stefansdottir, L., Thorleifsson, G., Sulem, P., Norland, K., Ferkingstad, E., Oddsson, A., Zink, F., Lund, S. H., Nawaz, M. S., Bragi Walters, G., Skuladottir, A. T., Gudjonsson, S. A., Einarsson, G., Halldorsson, G. H., Bjarnadottir, V., Sveinbjornsson, G., Helgadottir, A., Styrkarsdottir, U., Gudmundsson, L. J. & 26 others, Pedersen, Ole Birger Vesterager, Hansen, Thomas Folkmann, Werge, Thomas, Banasik, Karina, Troelsen, Anders, Skou, S. T., Thørner, L. W., Erikstrup, C., Nielsen, K. R., Mikkelsen, S., Jonsdottir, I., Bjornsson, A., Olafsson, I. H., Ulfarsson, E., Blondal, J., Vikingsson, A., Brunak, Søren, Ostrowski, Sisse Rye, Ullum, H., Thorsteinsdottir, U., Stefansson, H., Gudbjartsson, D. F., Thorgeirsson, T. E., Stefansson, K., DBDS Genetic Consortium, D. G. C. & GO Consortium, G. C., 2022, In: Nature Communications. 13, 13 p., 634.

Research output: Contribution to journal › Journal article › Research › peer-review

Rare coding variants in ten genes confer substantial risk for schizophrenia

Singh, T., Poterba, T., Curtis, D., Akil, H., Al Eissa, M., Barchas, J. D., Bass, N., Bigdeli, T. B., Breen, G., Bromet, E. J., Buckley, P. F., Bunney, W. E., Bybjerg-Grauholm, J., Byerley, W. F., Chapman, S. B., Chen, W. J., Churchhouse, C., Craddock, N., Cusick, C. M., DeLisi, L. & 91 others, Dodge, S., Escamilla, M. A., Eskelinen, S., Fanous, A. H., Faraone, S. V., Fiorentino, A., Francioli, L., Gabriel, S. B., Gage, D., Gagliano Taliun, S. A., Ganna, A., Genovese, G., Glahn, D. C., Grove, J., Hall, M. H., Hämäläinen, E., Heyne, H. O., Holi, M., Hougaard, D. M., Howrigan, D. P., Huang, H., Hwu, H. G., Kahn, R. S., Kang, H. M., Karczewski, K. J., Kirov, G., Knowles, J. A., Lee, F. S., Lehrer, D. S., Lescai, F., Malaspina, D., Marder, S. R., McCarroll, S. A., McIntosh, A. M., Medeiros, H., Milani, L., Morley, C. P., Morris, D. W., Mortensen, P. B., Myers, R. M., Nordentoft, Merete, O’Brien, N. L., Olivares, A. M., Ongur, D., Ouwehand, W. H., Palmer, D. S., Paunio, T., Quested, D., Rapaport, M. H., Rees, E., Rollins, B., Satterstrom, F. K., Schatzberg, A., Scolnick, E., Scott, L. J., Sharp, S. I., Sklar, P., Smoller, J. W., Sobell, J. L., Solomonson, M., Stahl, E. A., Stevens, C. R., Suvisaari, J., Tiao, G., Watson, S. J., Watts, N. A., Blackwood, D. H., Børglum, A. D., Cohen, B. M., Corvin, A. P., Esko, T., Freimer, N. B., Glatt, S. J., Hultman, C. M., McQuillin, A., Palotie, A., Pato, C. N., Pato, M. T., Pulver, A. E., St. Clair, D., Tsuang, M. T., Vawter, M. P., Walters, J. T., Werge, Thomas, Ophoff, R. A., Sullivan, P. F., Owen, M. J., Boehnke, M., O’Donovan, M. C., Neale, B. M. & Daly, M. J., 2022, In: Nature. 604, 7906, p. 509-516 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

Blokland, G. A. M., Grove, J., Chen, C. Y., Cotsapas, C., Tobet, S., Handa, R., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M. & 35 others, Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Hansen, M., Hansen, T., Li, T., Olsen, L., Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Hansen, C. S., Hansen, Thomas Folkmann, Nordentoft, Merete, Werge, Thomas, Plath, N., Schizophrenia Working Group of the Psychiatric Genomics Consortium, S. W. G. O. T. P. G. C., Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C., Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., Sex Differences Cross-Disorder Analysis Group of the Psychiatric Genomics Consortium, S. D. C. A. G. O. T. P. G. C. & iPSYCH, I., 2022, In: Biological Psychiatry. 91, 1, p. 107-117

Research output: Contribution to journal › Journal article › Research › peer-review

Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p

Weiner, D. J., Ling, E., Erdin, S., Tai, D. J. C., Yadav, R., Grove, J., Fu, J. M., Nadig, A., Carey, C., Baya, N., Bybjerg-Grauholm, J., Mortensen, P. B., Werge, T., Demontis, D., Mors, O., Nordentoft, M., Als, T. D., Baekvad-Hansen, M., Rosengren, A., Havdahl, A. & 33 others, Hedemand, A., Palotie, A., Chakravarti, A., Arking, D., Sulovari, A., Starnawska, A., Thiruvahindrapuram, B., de Leeuw, C., Carey, C., Ladd-Acosta, C., van der Merwe, C., Devlin, B., Cook, E. H., Eichler, E., Corfield, E., Dieleman, G., Schellenberg, G., Hakonarson, H., Coon, H., Dziobek, I., Vorstman, J., Girault, J., Sutcliffe, J. S., Duan, J., Nurnberger, J., Hallmayer, J., Buxbaum, J., Hinney, A., Larsson, H., Dalsgaard, Søren, iPSYCH Consortium, I. C., ASD Working Group of the Psychiatric Genomics Consortium, A. W. G. O. T. P. G. C. & ADHD Working Group of the Psychiatric Genomics Consortium, A. W. G. O. T. P. G. C., 2022, In: Nature Genetics. 54, p. 1630-1639

Research output: Contribution to journal › Journal article › Research › peer-review

Structural basis of organic cation transporter-3 inhibition

Khanppnavar, B., Maier, J., Herborg, Freja, Gradisch, R., Lazzarin, E., Luethi, D., Yang, J. W., Qi, C., Holy, M., Jäntsch, K., Kudlacek, O., Schicker, K., Werge, Thomas, Gether, Ulrik, Stockner, T., Korkhov, V. M. & Sitte, H. H., 2022, In: Nature Communications. 13, 1, 13 p., 6714.

Research output: Contribution to journal › Journal article › Research › peer-review

The population genomic legacy of the second plague pandemic

Gopalakrishnan, S., Ebenesersdóttir, S. S., Lundstrøm, I. K. C., Turner-Walker, G., Moore, K. H. S., Luisi, P., Margaryan, A., Martin, M. D., Ellegaard, M. R., Magnússon, Ó., Sigurðsson, Á., Snorradóttir, S., Magnúsdóttir, D. N., Laffoon, J. E., van Dorp, L., Liu, X., Moltke, I., Ávila-Arcos, M. C., Schraiber, J. G., Rasmussen, S. & 40 others, Juan, D., Gelabert, P., de-Dios, T., Fotaki, Anna Katerina, Iraeta Orbegozo, Miren, Vågene, Åshild Joanne, Denham, S. D., Christophersen, A., Stenøien, H. K., Vieira, Filipe Garrett, Liu, Shanlin, Günther, T., Kivisild, T., Moseng, O. G., Skar, B., Cheung, C., Sandoval-Velasco, Marcela, Wales, N., Schroeder, Hannes, Campos, P. F., Guðmundsdóttir, V. B., Sicheritz-Pontén, Thomas, Petersen, Bent, Halgunset, J., Gilbert, E., Cavalleri, G. L., Hovig, E., Kockum, I., Olsson, T., Alfredsson, L., Hansen, Thomas Folkmann, Werge, Thomas, Willerslev, Eske, Balloux, F., Marques-Bonet, T., Lalueza-Fox, C., Nielsen, Rasmus, Stefánsson, K., Helgason, A. & Gilbert, M Thomas P, 2022, In: Current Biology. 32, 21, p. 4743-4751.e6

Research output: Contribution to journal › Journal article › Research › peer-review

The sequences of 150,119 genomes in the UK Biobank

Halldorsson, B. V., Eggertsson, H. P., Moore, K. H. S., Hauswedell, H., Eiriksson, O., Ulfarsson, M. O., Palsson, G., Hardarson, M. T., Oddsson, A., Jensson, B. O., Kristmundsdottir, S., Sigurpalsdottir, B. D., Stefansson, O. A., Beyter, D., Holley, G., Tragante, V., Gylfason, A., Olason, P. I., Zink, F., Asgeirsdottir, M. & 27 others, Sverrisson, S. T., Sigurdsson, B., Gudjonsson, S. A., Sigurdsson, G. T., Halldorsson, G. H., Sveinbjornsson, G., Norland, K., Styrkarsdottir, U., Magnusdottir, D. N., Snorradottir, S., Kristinsson, K., Sobech, E., Pedersen, Ole Birger Vesterager, Brunak, Søren, Ostrowski, Sisse Rye, Banasik, Karina, Burgdorf, Kristoffer Sølvsten, Didriksen, Maria, Hansen, Thomas Folkmann, Hjalgrim, Henrik, Jemec, Gregor, Jennum, Poul, Jo­hans­son, Pär In­ge­mar , Ostrowski, Sisse Rye, Ullum, H., Werge, Thomas & DBDS Genetic Consortium, D. G. C., 2022, In: Nature. 607

Research output: Contribution to journal › Journal article › Research › peer-review

Copy Number Variants and Polygenic Risk Scores Predict Need of Care in Autism and/or ADHD Families

LaBianca, S., LaBianca, J., Pagsberg, Anne Katrine, Jakobsen, K. D., Appadurai, V., Buil, A. & Werge, Thomas, Jan 2021, In: Journal of Autism and Developmental Disorders. 51, 1, p. 276-285 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis

Bell, S., Rigas, A. S., Magnusson, M. K., Ferkingstad, E., Allara, E., Bjornsdottir, G., Ramond, A., Sørensen, E., Halldorsson, G. H., Paul, D. S., Burgdorf, K. S., Eggertsson, H. P., Howson, J. M. M., Thørner, L. W., Kristmundsdottir, S., Astle, W. J., Erikstrup, C., Sigurdsson, J. K., Vuckovic, D., Dinh, K. M. & 31 others, Tragante, V., Surendran, P., Pedersen, Ole Birger Vesterager, Vidarsson, B., Jiang, T., Paarup, H. M., Onundarson, P. T., Akbari, P., Nielsen, K. R., Lund, S. H., Juliusson, K., Magnusson, M. I., Frigge, M. L., Oddsson, A., Olafsson, I., Kaptoge, S., Hjalgrim, Henrik, Runarsson, G., Wood, A. M., Hansen, Thomas Folkmann, Burgdorf, Kristoffer Sølvsten, Jemec, Gregor, Jennum, Poul, Nielsen, K. R., Petersen, M., Werge, Thomas, Westergaard, David, Banasik, Karina, Brunak, Søren, Ullum, H. & DBDS Genomic Consortium, D. G. C., 2021, In: Communications Biology . 4, 1, 14 p., 156.

Research output: Contribution to journal › Journal article › Research › peer-review

A large-scale investigation into the role of classical HLA loci in multiple types of severe infections, with a focus on overlaps with autoimmune and mental disorders

Nudel, R., Allesøe, R. L., Thompson, W. K., Werge, Thomas, Rasmussen, Simon & Benros, Michael Eriksen, 2021, In: Journal of Translational Medicine. 19, 230.

Research output: Contribution to journal › Journal article › Research › peer-review

A polygenic resilience score moderates the genetic risk for schizophrenia

Hess, J. L., Tylee, D. S., Mattheisen, M., The Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH), Børglum, A. D., Als, T. D., Grove, J., Werge, T., Mortensen, P. B., Mors, O., Nordentoft, M., Hougaard, D. M., Byberg-grauholm, J., Bækvad-hansen, M., Greenwood, T. A., Tsuang, M. T., Curtis, D., Steinberg, S., Sigurdsson, E. & 6 others, Stefánsson, H., Stefánsson, K., Edenberg, H. J., Holmans, P., Faraone, S. V. & Glatt, S. J., 2021, In: Molecular Psychiatry. 26, p. 800–815

Research output: Contribution to journal › Journal article › Research › peer-review

Association and genetic overlap between clinical chemistry tests and migraine

Tanha, H. M. & The International Headache Genetics Consortium (IHGC), T. I. H. G. C. (., 2021, In: Cephalalgia. 41, 11-12, p. 1208-1221 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Amare, A. T., Schubert, K. O., Hou, L., Clark, S. R., Papiol, S., Cearns, M., Heilbronner, U., Degenhardt, F., Tekola-Ayele, F., Hsu, Y. H., Shekhtman, T., Adli, M., Akula, N., Akiyama, K., Ardau, R., Arias, B., Aubry, J. M., Backlund, L., Bhattacharjee, A. K., Bellivier, F. & 46 others, Benabarre, A., Bengesser, S., Biernacka, J. M., Birner, A., Brichant-Petitjean, C., Cervantes, P., Chen, H. C., Chillotti, C., Cichon, S., Cruceanu, C., Czerski, P. M., Dalkner, N., Dayer, A., Del Zompo, M., DePaulo, J. R., Étain, B., Jamain, S., Falkai, P., Forstner, A. J., Frisen, L., Frye, M. A., Fullerton, J. M., Nordentoft, Merete, Werge, Thomas, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., Wray, N. R., Ripke, S., Matthiesen, M., Agerbo, E., Bækvad-Hansen, M., Buttenschøn, H. N., Bybjerg-Grauholm, J., Grove, J., Hansen, C. S., Hansen, T. F., Hougaard, D. M., Krogh, J., Pedersen, C. B., Pedersen, M. G., Qvist, P., Thompson, W. K., Wang, Y., Weinsheimer, S. M., Mortensen, P. B., Christensen, J. V. & Børglum, A. D., 2021, In: Molecular Psychiatry. 26, p. 2457–2470 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors

Krebs, M. D., Themudo, G. E., Benros, Michael Eriksen, Mors, O., Børglum, A. D., Hougaard, D., Mortensen, P. B., Nordentoft, Merete, Gandal, M. J., Fan, C. C., Geschwind, D. H., Schork, A. J., Werge, Thomas & Thompson, W. K., 2021, In: Nature Communications. 12, 12 p., 6617.

Research output: Contribution to journal › Journal article › Research › peer-review

Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

Andlauer, T. F. M., Guzman-Parra, J., Streit, F., Strohmaier, J., González, M. J., Gil Flores, S., Cabaleiro Fabeiro, F. J., del Río Noriega, F., Perez, F. P., Haro González, J., Orozco Diaz, G., de Diego-Otero, Y., Moreno-Küstner, B., Auburger, G., Degenhardt, F., Heilmann-Heimbach, S., Herms, S., Hoffmann, P., Frank, J., Foo, J. C. & 26 others, Treutlein, J., Witt, S. H., Cichon, S., Kogevinas, M., Stahl, E. A., Breen, G., Forstner, A. J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J. R. I., Gaspar, H. A., de Leeuw, C. A., Steinberg, S., Pers, Tune H, Bækvad-Hansen, M., Pedersen, C. B., Pedersen, M. G., Hansen, C. S., Nordentoft, Merete, Werge, Thomas, Hansen, Thomas Folkmann, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, B. D. W. G. O. T. P. G. C. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, M. D. D. W. G. O. T. P. G. C., 2021, In: Molecular Psychiatry. 26, 4, p. 1286-1298 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

CYP2D6 Genotyping and Antipsychotic-Associated Extrapyramidal Adverse Effects in a Randomized Trial of Aripiprazole Versus Quetiapine Extended Release in Children and Adolescents, Aged 12-17 Years, With First Episode Psychosis

Rudå, Ditte, mfw347, mfw347, Decara, M. S., Klauber, D. G., Fagerlund, Birgitte, Møllegaard, J. R., Linnet, Kristian, Werge, Thomas, Correll, C. U., Fink-Jensen, Anders, Jürgens, Gesche & Pagsberg, Anne Katrine, 2021, In: Journal of Clinical Psychopharmacology. 41, 6, p. 667-672

Research output: Contribution to journal › Journal article › Research › peer-review