Lene Juel Rasmussen

Lene Juel Rasmussen

Managing director of centre, professor

Member of:

  • Web: Center for Healthy Aging

  • Web Track 1: Modifiable pathways of damage and repair in aging


  1. 2019
  2. Published

    Turtles maintain mitochondrial integrity but reduce mitochondrial respiratory capacity in the heart after cold acclimation and anoxia. / Bundgaard, Amanda; Qvortrup, Klaus; Rasmussen, Lene Juel; Fago, Angela.

    In: Journal of Experimental Biology, Vol. 222, No. 11, jeb200410, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print

    A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome. / Drost, Mark; Tiersma, Yvonne; Thompson, Bryony A.; Frederiksen, Jane H.; Keijzers, Guido; Glubb, Dylan; Kathe, Scott; Osinga, Jan; Westers, Helga; Pappas, Lisa; Boucher, Kenneth M.; Molenkamp, Siska; Zonneveld, José B.; van Asperen, Christi J.; Goldgar, David E.; Wallace, Susan S.; Sijmons, Rolf H.; Spurdle, Amanda B.; Rasmussen, Lene J.; Greenblatt, Marc S.; de Wind, Niels; Tavtigian, Sean V.

    In: Genetics in Medicine, 2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    From powerhouse to perpetrator—mitochondria in health and disease. / Fakouri, Nima B.; Hansen, Thomas Lau; Desler, Claus; Anugula, Sharath; Rasmussen, Lene Juel.

    In: Biology, Vol. 8, No. 2, 35, 2019.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis. / Hasan-Olive, Md Mahdi; Lauritzen, Knut H.; Ali, Mohammad; Rasmussen, Lene Juel; Storm-Mathisen, Jon; Bergersen, Linda H.

    In: Neurochemical Research, Vol. 44, No. 1, 2019, p. 22-37.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Mitochondrial oxidative phosphorylation capacity of cryopreserved cells. / Lauridsen, Poul Ejner; Rasmussen, Lene Juel; Desler, Claus.

    In: Mitochondrion, Vol. 47, 2019, p. 47-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    MERTK Acts as a costimulatory receptor on human cd8 t cells. / Peeters, Marlies J.W.; Dulkeviciute, Donata; Draghi, Arianna; Ritter, Cathrin; Rahbech, Anne; Skadborg, Signe K.; Seremet, Tina; Simoes, Ana Micaela Carnaz; Martinenaite, Evelina; Halldorsdottir, Holmfridur R.; Andersen, Mads Hald; Olofsson, Gitte Holmen; Svane, Inge Marie; Rasmussen, Lene Juel; Met, Ozcan; Becker, Jeurgen C.; Donia, Marco; Desler, Claus; Straten, Per Thor.

    In: Cancer Immunology Research, Vol. 7, No. 9, 2019, p. 1472-1484.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2018
  9. Published

    The role of mitochondrial dysfunction in the progression of Alzheimer’s disease. / Desler, Claus; Lillenes, Meryl S.; Tønjum, Tone; Rasmussen, Lene Juel.

    In: Current Medicinal Chemistry, Vol. 25, No. 40, 2018, p. 5578 - 5587.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms. / Jakobsen, Emil; Lange, Sofie C; Andersen, Jens Velde; Madsen, Claus Desler; Kihl, Henriette Filholm; Hohnholt, Michaela; Stridh, Malin H; Rasmussen, Lene Juel; Waagepetersen, Helle S.; Bak, Lasse Kristoffer.

    In: Biochemical Pharmacology, Vol. 155, 2018, p. 92-101.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Initial brain aging : heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus. / Thomsen, Kirsten; Yokota, Takashi; Hasan-Olive, Md Mahdi; Sherazi, Niloofar; Fakouri, Nima Borhan; Desler, Claus; Regnell, Christine Elisabeth; Larsen, Steen; Rasmussen, Lene Juel; Dela, Flemming; Bergersen, Linda Hildegard; Lauritzen, Martin.

    In: Neurobiology of Aging, Vol. 61, 2018, p. 215-224.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2017
  13. Published

    Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis. / Fakouri, Nima Borhan; Durhuus, Jon Ambaek; Regnell, Christine Elisabeth; Angleys, Maria; Desler, Claus; Hasan-Olive, Mahdi; Martin-Pardillos, Ana; Tsaalbi-Shtylik, Anastasia; Thomsen, Kirsten; Lauritzen, Martin; Bohr, Vilhelm A.; de Wind, Niels; Bergersen, Linda Hildegard; Rasmussen, Lene Juel.

    In: Scientific Reports, Vol. 7, 12480, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage. / Hopkinson, Branden M; Madsen, Claus Desler; Kalisz, Mark; Vestentoft, Peter Siig; Juel Rasmussen, Lene; Bisgaard, Hanne Cathrine.

    In: Oxidative Medicine and Cellular Longevity, Vol. 2017, 5080128, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Nanomaterial-induced cell death in pulmonary and hepatic cells following exposure to three different metallic materials : The role of autophagy and apoptosis. / Kermanizadeh, Ali; Jantzen, Kim; Ward, Michael B; Durhuus, Jon Ambæk; Juel Rasmussen, Lene; Loft, Steffen; Møller, Peter.

    In: Nanotoxicology, Vol. 11, No. 2, 03.2017, p. 184-200.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    DNA mismatch repair and its many roles in eukaryotic cells. / Liu, Dekang; Keijzers, Guido; Rasmussen, Lene Juel.

    In: Mutation Research - Reviews in Mutation Research, Vol. 773, 07.2017, p. 174-187.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro. / Liu, Dekang; Frederiksen, Jane H; Liberti, Sascha E; Lützen, Anne; Keijzers, Guido; Pena-Diaz, Javier; Rasmussen, Lene Juel.

    In: Nucleic Acids Research, Vol. 45, No. 16, 19.09.2017, p. 9427-9440.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions. / Martín-Pardillos, Ana; Tsaalbi-Shtylik, Anastasia; Chen, Si; Lazare, Seka; Van Os, Ronald P.; Dethmers-Ausema, Albertina; Fakouri, Nima Borhan; Bosshard, Matthias; Aprigliano, Rossana; Van Loon, Barbara; Salvatori, Daniela C.F.; Hashimoto, Keiji; Van Der Spek, Celia Dingemanse; Moriya, Masaaki; Rasmussen, Lene Juel; De Haan, Gerald; Raaijmakers, Marc H.G.P.; De Wind, Niels.

    In: Blood, Vol. 130, No. 13, 2017, p. 1523-1534.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations. / Nielsen, Sofie V,; Stein, Amelie; Dinitzen, Alexander B.; Papaleo, Elena; Tatham, Michael H.; Poulsen, Esben Guldahl; Kassem, Maher Mahmoud; Rasmussen, Lene Juel; Lindorff-Larsen, Kresten; Hartmann-Petersen, Rasmus.

    In: PLoS Genetics, Vol. 13, No. 4, e1006739, 19.04.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    EXO1 (Exonuclease 1). / Rasmussen, Lene Juel; Keijzers, Guido.

    Encyclopedia of Signaling Molecules . ed. / Sangdun Choi. New York : Springer, 2017.

    Research output: Chapter in Book/Report/Conference proceedingEncyclopedia chapterResearch

  21. Published

    Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours. / Rudolph, Christiane; Melau, Cecilie; Nielsen, John E.; Jensen, Kristina Vile; Liu, Dekang; Pena-Diaz, Javier; Meyts, Ewa Rajpert-De; Rasmussen, Lene Juel; Jorgensen, Anne.

    In: Cellular Oncology, Vol. 40, No. 4, 2017, p. 341-355.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Bacterial infection increases risk of carcinogenesis by targeting mitochondria. / Strickertsson, Jesper A.B.; Desler, Claus; Rasmussen, Lene Juel.

    In: Seminars in Cancer Biology, Vol. 47, 12.2017, p. 95-100.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1. / Vohra, Rupali; Gurubaran, Iswariyaraja Sridevi; Henriksen, Ulrik ; Bergersen, Linda Hildegaard; Rasmussen, Lene Juel; Desler, Claus; Skytt, Dorte Marie; Kolko, Miriam.

    In: Mitochondrion, Vol. 36, 2017, p. 52-59.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2016
  25. Published
  26. Published

    Interventions for age-related diseases : Shifting the paradigm. / Figueira, Inês; Fernandes, Adelaide; Mladenovic Djordjevic, Aleksandra; Lopez-Contreras, Andres; Henriques, Catarina M; Selman, Colin; Ferreiro, Elisabete; Gonos, Efstathios S; Trejo, José Luis; Misra, Juhi; Rasmussen, Lene Juel; Xapelli, Sara; Ellam, Timothy; Bellantuono, Ilaria.

    In: Mechanisms of Ageing and Development, Vol. 160, 12.2016, p. 69-92.

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    Exonuclease 1 and its versatile roles in DNA repair. / Keijzers, Guido; Liu, Dekang; Rasmussen, Lene Juel.

    In: Critical Reviews in Biochemistry and Molecular Biology, Vol. 51, No. 6, 05.08.2016, p. 440–451.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks. / Lu, Huiming; Shamanna, Raghavendra A; Keijzers, Guido; Anand, Roopesh; Rasmussen, Lene Juel; Cejka, Petr; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Cell Reports, Vol. 16, No. 1, 28.06.2016, p. 161-173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Acquired Localized Cutis Laxa due to Increased Elastin Turnover. / Nygaard, Rie Harboe; Maynard, Scott; Schjerling, Peter; Kjær, Michael; Qvortrup, Klaus; Bohr, Vilhelm A; Rasmussen, Lene J; Jemec, Gregor B E; Heidenheim, Michael.

    In: Case Reports in Dermatology, Vol. 8, No. 1, 14.06.2016, p. 42-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

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