Is development of hyperalgesia, allodynia and myoclonus related to morphine metabolism during long-term administration? Six case histories
Research output: Contribution to journal › Journal article › Research › peer-review
Recently, clinical reports have suggested a relationship between the occurrence of hyperalgesia, allodynia and/or myoclonus and treatment with high doses of morphine in humans. Although few clinical descriptions of these phenomena are available, experimental work supports the notion that high doses of morphine may play a pathogenetic role in the observed behavioural syndrome.
| Original language | English |
|---|---|
| Journal | Acta Anaesthesiologica Scandinavica |
| Volume | 42 |
| Issue number | 9 |
| Pages (from-to) | 1070-5 |
| Number of pages | 6 |
| ISSN | 0001-5172 |
| Publication status | Published - Oct 1998 |
- Aged, Analgesics, Opioid, Female, Glucuronosyltransferase, Humans, Hyperalgesia, Male, Middle Aged, Morphine, Morphine Derivatives, Myoclonus
Research areas
Links
- https://onlinelibrary.wiley.com/doi/10.1111/j.1399-6576.1998.tb05378.x/abstract
Final published version
ID: 46099451