Tobias Gustavsson

Tobias Gustavsson

Associate Professor

Member of:

  • VAR2CSA team

  • CMP-BIOENGINEERING

ORCID: 0000-0003-0243-2248

Publication year:
All
1 - 25 out of 29Page size: 25
  1. 2023
  2. Published

    Bispecific T cell-engager targeting oncofetal chondroitin sulfate induces complete tumor regression and protective immune memory in mice

    Skeltved, Nanna, Nordmaj, Mie Anemone, Pagh-Berendtsen, Nicolai, Dagil, Robert, Stormer, E. M. R., Al-Nakouzi, N., Jiang, K., Aicher, A., Heeschen, C., Gustavsson, Tobias, Choudhary, Swati, Gögenur, Ismail, Christensen, Jan Pravsgaard, Theander, Thor Grundtvig, Daugaard, M., Salanti, Ali & Nielsen, Morten Agertoug, 2023, In: Journal of Experimental & Clinical Cancer Research. 42, 16 p., 106.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    First-in-human use of a modular capsid virus-like vaccine platform: An open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

    Smit, M. J., Sander, A. F., Ariaans, M. B. P. A., Fougeroux, C., Heinzel, C., Fendel, R., Esen, M., Kremsner, P. G., Ter Heine, R., Wertheim, H. F., Idorn, M., Paludan, S. R., Underwood, A. P., Binderup, A., Ramirez, S., Bukh, J., Soegaard, M., Erdogan, S. M., Gustavsson, T., Clemmensen, S. & 14 others, Theander, Thor Grundtvig, Salanti, Ali, Hamborg, M., de Jongh, W. A., McCall, M. B. B., Nielsen, Morten Agertoug, Mordmüller, B. G., COUGH-1 trial study group, C. T. S. G., Dagil, Robert, Goksøyr, L., Hulen, T. M., Brygger, C. M. J., Khalifé, P. K. & Vidal-Calvo, E. E., 2023, In: The Lancet Microbe. 4, 3, p. e140-e148

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Malaria biomimetic for tumor targeted drug delivery

    Pihl, J., Clausen, T. M., Zhou, J., Krishnan, N., Ørum-Madsen, M. S., Gustavsson, Tobias, Dagil, Robert, Daugaard, M., Choudhary, Swati, Foged, Camilla, Esko, J. D., Zhang, L., Fang, R. H. & Salanti, Ali, 2023, In: ACS Nano. 17, 14, p. 13500–13509

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2022
  6. Published

    Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA

    Raghavan, Sai Sundar Rajan, Dagil, Robert, Lopez-Perez, Mary, Conrad, J., Bassi, Maria Rosaria, Quintana Varon, Maria del Pilar, Choudhary, Swati, Gustavsson, Tobias, Wang, Yong, Gourdon, Pontus Emanuel, Ofori, M. F., Christensen, S. B., Minja, D. T. R., Schmiegelow, Christentze, Nielsen, Morten Agertoug, Barfod, Lea Klingenberg, Hviid, Lars, Salanti, Ali, Lavstsen, Thomas & Wang, Kaituo, 2022, In: PLoS Pathogens. 18, 11, e1010924.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells

    Wang, Chris Kedong, Nelepcu, I., Hui, D., Oo, H. Z., Truong, S., Zhao, S., Tahiry, Z., Esfandnia, S., Ghaidi, F., Adomat, H., Dagil, Robert, Gustavsson, Tobias, Choudhary, Swati, Salanti, Ali, Sorensen, P. H., Al Nakouzi, N. & Daugaard, M., 2022, In: Scientific Reports. 12, 3075.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer

    Al Nakouzi, N., Wang, C. K., Oo, H. Z., Nelepcu, I., Lallous, N., Spliid, C. B., Khazamipour, N., Lo, J., Truong, S., Collins, C., Hui, D., Esfandnia, S., Adomat, H., Clausen, T. M., Gustavsson, T., Choudhary, S., Dagil, R., Corey, E., Wang, Y., Chauchereau, A. & 6 others, Fazli, L., Esko, J. D., Salanti, Ali, Nelson, P. S., Gleave, M. & Daugaard, M., 2022, In: Nature Communications. 13, 4760.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2021
  10. Published

    Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

    Fougeroux, C., Goksøyr, L., Idorn, M., Soroka, V., Myeni, S. K., Dagil, R., Janitzek, C. M., Søgaard, M., Aves, K-L., Horsted, E. W., Erdogan, S. M., Gustavsson, T., Dorosz, J., Clemmensen, S., Fredsgaard, L., Thrane, S., Vidal-Calvo, E. E., Khalifé, P., Hulen, T. M., Choudhary, S. & 27 others, Theisen, Michael, Singh, S. K., Garcia-Senosiain, A., Van Oosten, L., Pijlman, G., Hierzberger, B., Domeyer, T., Nalewajek, B. W., Strøbæk, A., Skrzypczak, M., Andersson, L. F., Buus, Søren, Buus, Anette Stryhn, Christensen, Jan Pravsgaard, Dalebout, T. J., Iversen, Kasper, Harritshøj, L. H., Mordmüller, B., Ullum, H., Reinert, L. S., de Jongh, W. A., Kikkert, M., Paludan, S. R., Theander, Thor Grundtvig, Nielsen, Morten Agertoug, Salanti, Ali & Sander, Adam F. , 2021, In: Nature Communications. 12, 1, p. 324

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Cryo-EM reveals the architecture of placental malaria VAR2CSA and provides molecular insight into chondroitin sulfate binding

    Wang, Kaituo, Dagil, Robert, Lavstsen, Thomas, Misra, S. K., Spliid, C. B., Wang, Yong, Gustavsson, Tobias, Sandoval, D. R., Vidal-Calvo, E. E., Choudhary, Swati, Agerbæk, Mette Ørskov, Lindorff-Larsen, Kresten, Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sharp, J. S., Clausen, Thomas Mandel, Gourdon, Pontus Emanuel & Salanti, Ali, 2021, In: Nature Communications. 12, 1, 10 p., 2956.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Detection of VAR2CSA‐captured colorectal cancer cells from blood samples by real‐time reverse transcription PCR

    Bang‐christensen, S. R., Katerov, V., Jørgensen, Amalie Mundt, Gustavsson, Tobias, Choudhary, Swati, Theander, Thor Grundtvig, Salanti, Ali, Allawi, H. T. & Agerbæk, Mette Ørskov, 2021, In: Cancers. 13, 23, 5881.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Development of a bispecific immune engager using a recombinant malaria protein

    Nordmaj, Mie Anemone, Roberts, M. E., Sachse, E. S., Dagil, Robert, Andersen, Anne Poder, Skeltved, Nanna, Grunddal, Kaare Villum, Erdogan, Sayit Mahmut, Choudhary, Swati, Gustavsson, Tobias, Ørum-madsen, M. S., Moskalev, I., Tian, W., Yang, Zhang, Clausen, Thomas Mandel, Theander, Thor Grundtvig, Daugaard, M., Nielsen, Morten Agertoug & Salanti, Ali, 2021, In: Cell Death & Disease. 12, 4, 11 p., 353.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Oncofetal chondroitin sulfate is a highly expressed therapeutic target in non-small cell lung cancer

    Oo, H. Z., Lohinai, Z., Khazamipour, N., Lo, J., Kumar, G., Pihl, J., Adomat, H., Nabavi, N., Behmanesh, H., Zhai, B., Dagil, R., Choudhary, S., Gustavsson, T., Clausen, T. M., Esko, J. D., Allen, J. W., Thompson, M. A., Tran, N. L., Moldvay, J., Dome, B. & 4 others, Salanti, Ali, Al-Nakouzi, N., Weiss, G. J. & Daugaard, M., 2021, In: Cancers. 13, 17, 16 p., 4489.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The specificity of the malarial VAR2CSA protein for chondroitin sulfate depends on 4-O-sulfation and ligand accessibility

    Spliid, C. B., Toledo, A. G., Sanderson, P., Mao, Y., Gatto, F., Gustavsson, Tobias, Choudhary, Swati, Saldanha, A. L., Vogelsang, R. P., Gögenur, Ismail, Theander, Thor Grundtvig, Leach, F. E., Amster, I. J., Esko, J. D., Salanti, Ali & Clausen, Thomas Mandel, 2021, In: The Journal of Biological Chemistry. 297, 6, 15 p., 101391.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. 2020
  17. Published

    A simple method for detecting oncofetal chondroitin sulfate glycosaminoglycans in bladder cancer urine

    Clausen, Thomas Mandel, Kumar, G., Ibsen, E. K., Ørum-Madsen, M. S., Hurtado-Coll, A., Gustavsson, Tobias, Agerbæk, Mette Ørskov, Gatto, F., Todenhöfer, T., Basso, U., Knowles, M. A., Sanchez-Carbayo, M., Salanti, Ali, Black, P. C. & Daugaard, M., 2020, In: Cell Death Discovery. 6, 65.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    An affinity chromatography and glycoproteomics workflow to profile the chondroitin sulfate proteoglycans that interact with malarial VAR2CSA in the placenta and in cancer

    Toledo, A. G., Pihl, J., Spliid, C. B., Persson, A., Nilsson, J., Pereira, M. A., Gustavsson, Tobias, Choudhary, Swati, Zarni Oo, H., Black, P. C., Daugaard, M., Esko, J. D., Larson, G., Salanti, Ali & Clausen, Thomas Mandel, 2020, In: Glycobiology. 30, 12, p. 989-1002 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Optimization of rVAR2-based isolation of cancer cells in blood for building a robust assay for clinical detection of circulating tumor cells

    Sand, Nicolai Tue, Petersen, T. B., Bang-Christensen, S. R., Ahrens, T. D., Løppke, Caroline Bang, Jørgensen, A. M., Gustavsson, Tobias, Choudhary, Swati, Theander, Thor Grundtvig, Salanti, Ali & Agerbæk, Mette Ørskov, 2020, In: International Journal of Molecular Sciences . 21, 7, 2401.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. 2019
  21. Published

    Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein

    Bang-Christensen, S. R., Pedersen, R. S., Pereira, M. A., Clausen, T. M., Løppke, C., Sand, N. T., Ahrens, T. D., Jørgensen, A. M., Lim, Y. C., Goksøyr, L., Choudhary, S., Gustavsson, T., Dagil, R., Daugaard, M., Sander, A. F., Torp, M. H., Søgaard, M., Theander, T. G., Østrup, O., Lassen, U. & 3 others, Hamerlik, P., Salanti, Ali & Agerbæk, Mette Ørskov, 2019, In: Cells. 8, 9, 21 p., 998.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2018
  23. Published

    The GAGOme: a cell-based library of displayed glycosaminoglycans

    Chen, Yen-Hsi, Narimatsu, Yoshiki, Clausen, Thomas Mandel, Gomes, C., Karlsson, R., Steentoft, C., Spliid, C. B., Gustavsson, Tobias, Salanti, Ali, Persson, A., Malmström, A., Willén, D., Ellervik, U., Bennett, Eric Paul, Mao, Y., Clausen, Henrik & Yang, Zhang, 2018, In: Nature Methods. 15, 11, p. 881-888

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner

    Agerbæk, Mette Ørskov, Bang-Christensen, S. R., Yang, M., Clausen, Thomas Mandel, Pereira, M. A., Sharma, S., Ditlev, S. B., Nielsen, Morten Agertoug, Choudhary, Swati, Gustavsson, Tobias, Sorensen, P. H., Meyer, T., Propper, D., Shamash, J., Theander, Thor Grundtvig, Aicher, A., Daugaard, M., Heeschen, C. & Salanti, Ali, 2018, In: Nature Communications. 9, 1, 13 p., 3279.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2017
  26. Published

    An oncofetal glycosaminoglycan modification provides therapeutic access to Cisplatin-resistant bladder cancer

    Seiler, R., Oo, H. Z., Tortora, D., Clausen, T. M., Wang, C. K., Kumar, G., Ayres Pereira, M., Ørum-Madsen, M. S., Agerbæk, M. Ø., Gustavsson, T., Nordmaj, M. A., Rich, J. R., Lallous, N., Fazli, L., Lee, S., Douglas, J., Todenhöfer, T., Esfandnia, S., Battsogt, D., Babcook, J. S. & 10 others, Al Nakouzi, N., Crabb, S. J., Moskalev, I., Kiss, B., Davicioni, E., Thalmann, G. N., Rennie, P. S., Black, P. C., Salanti, Ali & Daugaard, M., 2017, In: European Urology Supplements. 72, 1, p. 142-150 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2016
  28. Published

    Molecular dissection of placental malaria protein VAR2CSA interaction with a chemo-enzymatically synthesized chondroitin sulfate library

    Sugiura, N., Clausen, Thomas Mandel, Shioiri, T., Gustavsson, Tobias, Watanabe, H. & Salanti, Ali, Dec 2016, In: Glycoconjugate Journal. 33, 6, p. 985-994 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting

    Clausen, Thomas Mandel, Ayres Pereira, M., Oo, H. Z., Resende, M., Gustavsson, Tobias, Mao, Y., Sugiura, N., Liew, J., Fazli, L., Theander, Thor Grundtvig, Daugaard, M. & Salanti, Ali, Jul 2016, In: Sensing and Bio-Sensing Research. 9, p. 23-30 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Bacterial superglue enables easy development of efficient virus-like particle based vaccines

    Thrane, Susan, Janitzek, C. M., Matondo, S., dos Santos Marques Resende, M., Gustavsson, Tobias, De Jongh, W. A., Clemmensen, S., Roeffen, W., van de Vegte-Bolmer, M., van Gemert, G. J., Sauerwein, R., Schiller, J. T., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 27 Apr 2016, In: Journal of Nanobiotechnology. 14, 16 p., 30.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2015
  32. Published

    Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein

    Salanti, A., Clausen, T. M., Agerbæk, M. Ø., Al Nakouzi, N., Dahlbäck, M., Oo, H. Z., Lee, S., Gustavsson, T., Rich, J. R., Hedberg, B. J., Mao, Y., Barington, L., Pereira, M. A., LoBello, J., Endo, M., Fazli, L., Soden, J., Wang, C. K., Sander, A. F., Dagil, R. & 15 others, Thrane, Susan, Holst, Peter Johannes, Meng, L., Favero, F., Weiss, G. J., Nielsen, Morten Agertoug, Freeth, J., Nielsen, T. O., Zaia, J., Tran, N. L., Trent, J., Babcook, J. S., Theander, Thor Grundtvig, Sorensen, P. H. & Daugaard, M., 2015, In: Cancer Cell. 28, 4, p. 500-14 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2012
  34. Published

    Biphasic kinetic behavior of E. coli WrbA, an FMN-dependent NAD(P)H:quinone oxidoreductase

    Kishko, I., Harish, B., Zayats, V., Reha, D., Tenner, B., Beri, D., Gustavsson, Tobias, Ettrich, R. & Carey, J., 2012, In: PLOS ONE. 7, 8, p. e43902

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. 2010
  36. Published

    A cytochrome c fusion protein domain for convenient detection, quantification, and enhanced production of membrane proteins in Escherichia coli--expression and characterization of cytochrome-tagged Complex I subunits

    Gustavsson, Tobias, Trane, M., Moparthi, V. K., Miklovyte, E., Moparthi, L., Górecki, K., Leiding, T., Arsköld, S. P. & Hägerhäll, C., Aug 2010, In: Protein Science. 19, 8, p. 1445-60 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

Previous 1 2 Next

ID: 126250167