Thomas Andrew Qvistgaard Jepps
Associate Professor
Physiology of circulation, kidney and lung
Blegdamsvej 3
2200 København N.
- 2019
- Published
KCNQ5 activation is a unifying molecular mechanism shared by genetically and culturally diverse botanical hypotensive folk medicines
Manville, R. W., van der Horst, Jennifer, Redford, K. E., Katz, B. B., Jepps, Thomas Andrew Qvistgaard & Abbott, G. W., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 21236-21245Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Impaired Kv7 channel function in cerebral arteries of a tauopathy mouse model (rTg4510)
de Jong, I. E. M. & Jepps, Thomas Andrew Qvistgaard, Dec 2018, In: Physiological Reports. 6, 23, 10 p., e13920 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contractile responses in intact and mucosa-denuded human ureter: a comparison with urinary bladder detrusor preparations
Roedel, M., Ravens, U., Kasper, M., Wirth, M. P., Jepps, Thomas Andrew Qvistgaard & Propping, S., 1 Aug 2018, In: Naunyn-Schmiedeberg's Archives of Pharmacology. 391, 8, p. 773-782 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Angiotensin II Promotes KV7.4 Channels Degradation Through Reduced Interaction With HSP90 (Heat Shock Protein 90)
Barrese, V., Stott, J. B., Figueiredo, H. B., Aubdool, A. A., Hobbs, A. J., Jepps, Thomas Andrew Qvistgaard, McNeish, A. J. & Greenwood, I. A., Jun 2018, In: Hypertension. 71, 6, p. 1091-1100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries
Khammy, M. M., Kim, S., Bentzen, Bo Hjorth, Lee, S., Choi, I., Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: British Journal of Pharmacology. 175, 3, p. 501-516 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microtubule Regulation of Kv7 Channels Orchestrates cAMP-Mediated Vasorelaxations in Rat Arterial Smooth Muscle
Lindman, J., Khammy, M. M., Lundegaard, Pia Rengtved, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: Hypertension. 71, 2, p. 336-345 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Unravelling the complexities of vascular smooth muscle ion channels: Fine tuning of activity by ancillary subunits
Jepps, Thomas Andrew Qvistgaard, Oct 2017, In: Pharmacology & Therapeutics. 178, p. 57-66 10 p.Research output: Contribution to journal › Review › Research › peer-review
- 2016
- Published
Kcne4 Deletion Sex-Dependently Alters Vascular Reactivity
Abbott, G. W. & Jepps, Thomas Andrew Qvistgaard, 7 Oct 2016, In: Journal of Vascular Research. 53, 3-4, p. 138-148 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension
Carr, G., Barrese, V., Stott, J. B., Povstyan, O. V., Jepps, Thomas Andrew Qvistgaard, Figueiredo, H. B., Zheng, D., Jamshidi, Y. & Greenwood, I. A., 7 Jul 2016, In: Cardiovascular Research. 112, p. 581-589 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats
Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter, Greenwood, I. A. & Dalsgaard, T., May 2016, In: British Journal of Pharmacology. 173, 9, p. 1478-1490 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts
Skarsfeldt, M. A., Jepps, Thomas Andrew Qvistgaard, Bomholtz, Sofia Hammami, Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, Jesper Hastrup, Diness, J. G., Grunnet, M., Schmitt, Nicole, Olesen, Søren-Peter & Bentzen, Bo Hjorth, Apr 2016, In: Pfluegers Archiv. 468, 4, p. 643-654 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone
Jepps, Thomas Andrew Qvistgaard, Carr, G., Lundegaard, Pia Rengtved, Olesen, Søren-Peter & Greenwood, I. A., 15 Dec 2015, In: Journal of Physiology. 593, 24, p. 5325-40 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats
Stott, J. B., Barrese, V., Jepps, Thomas Andrew Qvistgaard, Leighton, E. V. & Greenwood, I. A., Mar 2015, In: Hypertension. 65, 3, p. 676-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
KV7 potassium channels: a new therapeutic target in smooth muscle disorders
Stott, J. B., Jepps, Thomas Andrew Qvistgaard & Greenwood, I. A., 12 Dec 2014, In: Drug Discovery Today. 19, 4, p. 413-424 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vasorelaxant effects of novel Kv7.4 channel enhancers ML213 and NS15370
Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Stott, J. B., Povstyan, O. V., Sivaloganathan, K., Dalby-Brown, W. & Greenwood, I. A., 9 Jun 2014, In: British Journal of Pharmacology. 171, 19, p. 4413-4424 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity
Chadha, P. S., Jepps, Thomas Andrew Qvistgaard, Carr, G., Stott, J. B., Zhu, H., Cole, W. C. & Greenwood, I. A., Apr 2014, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 34, 4, p. 887-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Contribution of KV7 Channels to Basal Coronary Flow and Active Response to Ischemia
Khanamiri, S., Soltysinska, E., Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Chadha, P. S., Schmitt, Nicole, Greenwood, I. A. & Olesen, Søren-Peter, 30 Sep 2013, In: Hypertension. 62, 6, p. 1090-1097 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders
Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter & Greenwood, I. A., 2013, In: British Journal of Pharmacology. 168, 1, p. 19-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Pharmacological dissection of K(v)7.1 channels in systemic and pulmonary arteries
Chadha, P. S., Zunke, F., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Linders, J. T. M., Schwake, M., Towart, R. & Greenwood, I. A., Jun 2012, In: British Journal of Pharmacology. 166, 4, p. 1377-87 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced KCNQ4-encoded voltage-dependent potassium channel activity underlies impaired ß-adrenoceptor-mediated relaxation of renal arteries in hypertension
Chadha, P. S., Zunke, F., Zhu, H., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter, Cole, W. C., Moffatt, J. D. & Greenwood, I., 2012, In: Hypertension. 59, 4, p. 877-84 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Downregulation of Kv7.4 channel activity in primary and secondary hypertension
Jepps, Thomas Andrew Qvistgaard, Chadha, P. S., Davis, A. J., Harhun, M. I., Cockerill, G. W., Olesen, S. P., Hansen, R. S. & Greenwood, I. A., 2 Aug 2011, In: Circulation. 124, 5, p. 602-11 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression and function of the K+ channel KCNQ genes in human arteries
Ng, F. L., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Harhun, M. I., Yeung, S. Y., Wan, A., Reddy, M., Melville, D., Nardi, A., Khong, T. K. & Greenwood, I. A., Jan 2011, In: British Journal of Pharmacology. 162, 1, p. 42-53 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Expression profile and protein translation of TMEM16A in murine smooth muscle
Davis, A. J., Forrest, A. S., Jepps, Thomas Andrew Qvistgaard, Valencik, M. L., Wiwchar, M., Singer, C. A., Sones, W. R., Greenwood, I. A. & Leblanc, N., Nov 2010, In: A J P: Cell Physiology (Online). 299, 5, p. C948-59Research output: Contribution to journal › Journal article › Research
- 2009
- Published
Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles
Jepps, Thomas Andrew Qvistgaard, Greenwood, I. A., Moffatt, J. D., Sanders, K. M. & Ohya, S., Jul 2009, In: A J P: Gastrointestinal and Liver Physiology (Online). 297, 1, p. G107-15Research output: Contribution to journal › Journal article › Research
ID: 51475012
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352
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MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
130
downloads
Impaired Kv7 channel function in cerebral arteries of a tauopathy mouse model (rTg4510)
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
93
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Genome-wide association study identifies locus at chromosome 2q32.1 associated with syncope and collapse
Research output: Contribution to journal › Journal article › Research › peer-review
Published