Thomas Andrew Qvistgaard Jepps

Thomas Andrew Qvistgaard Jepps

Associate Professor


  1. 2019
  2. Published

    KCNQ5 activation is a unifying molecular mechanism shared by genetically and culturally diverse botanical hypotensive folk medicines

    Manville, R. W., van der Horst, Jennifer, Redford, K. E., Katz, B. B., Jepps, Thomas Andrew Qvistgaard & Abbott, G. W., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 42, p. 21236-21245

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2018
  4. Published

    Impaired Kv7 channel function in cerebral arteries of a tauopathy mouse model (rTg4510)

    de Jong, I. E. M. & Jepps, Thomas Andrew Qvistgaard, Dec 2018, In: Physiological Reports. 6, 23, 10 p., e13920 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Contractile responses in intact and mucosa-denuded human ureter: a comparison with urinary bladder detrusor preparations

    Roedel, M., Ravens, U., Kasper, M., Wirth, M. P., Jepps, Thomas Andrew Qvistgaard & Propping, S., 1 Aug 2018, In: Naunyn-Schmiedeberg's Archives of Pharmacology. 391, 8, p. 773-782 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Angiotensin II Promotes KV7.4 Channels Degradation Through Reduced Interaction With HSP90 (Heat Shock Protein 90)

    Barrese, V., Stott, J. B., Figueiredo, H. B., Aubdool, A. A., Hobbs, A. J., Jepps, Thomas Andrew Qvistgaard, McNeish, A. J. & Greenwood, I. A., Jun 2018, In: Hypertension. 71, 6, p. 1091-1100 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries

    Khammy, M. M., Kim, S., Bentzen, Bo Hjorth, Lee, S., Choi, I., Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: British Journal of Pharmacology. 175, 3, p. 501-516 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Microtubule Regulation of Kv7 Channels Orchestrates cAMP-Mediated Vasorelaxations in Rat Arterial Smooth Muscle

    Lindman, J., Khammy, M. M., Lundegaard, Pia Rengtved, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: Hypertension. 71, 2, p. 336-345 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2017
  10. Published

    Unravelling the complexities of vascular smooth muscle ion channels: Fine tuning of activity by ancillary subunits

    Jepps, Thomas Andrew Qvistgaard, Oct 2017, In: Pharmacology & Therapeutics. 178, p. 57-66 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. 2016
  12. Published

    Kcne4 Deletion Sex-Dependently Alters Vascular Reactivity

    Abbott, G. W. & Jepps, Thomas Andrew Qvistgaard, 7 Oct 2016, In: Journal of Vascular Research. 53, 3-4, p. 138-148 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension

    Carr, G., Barrese, V., Stott, J. B., Povstyan, O. V., Jepps, Thomas Andrew Qvistgaard, Figueiredo, H. B., Zheng, D., Jamshidi, Y. & Greenwood, I. A., 7 Jul 2016, In: Cardiovascular Research. 112, p. 581-589 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Molecular and functional characterization of Kv 7 channels in penile arteries and corpus cavernosum of healthy and metabolic syndrome rats

    Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter, Greenwood, I. A. & Dalsgaard, T., May 2016, In: British Journal of Pharmacology. 173, 9, p. 1478-1490 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    pH-dependent inhibition of K2P3.1 prolongs atrial refractoriness in whole hearts

    Skarsfeldt, M. A., Jepps, Thomas Andrew Qvistgaard, Bomholtz, Sofia Hammami, Abildgaard, L., Sørensen, U. S., Gregers, E., Svendsen, Jesper Hastrup, Diness, J. G., Grunnet, M., Schmitt, Nicole, Olesen, Søren-Peter & Bentzen, Bo Hjorth, Apr 2016, In: Pfluegers Archiv. 468, 4, p. 643-654 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2015
  17. Published

    Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone

    Jepps, Thomas Andrew Qvistgaard, Carr, G., Lundegaard, Pia Rengtved, Olesen, Søren-Peter & Greenwood, I. A., 15 Dec 2015, In: Journal of Physiology. 593, 24, p. 5325-40 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats

    Stott, J. B., Barrese, V., Jepps, Thomas Andrew Qvistgaard, Leighton, E. V. & Greenwood, I. A., Mar 2015, In: Hypertension. 65, 3, p. 676-82 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2014
  20. Published

    KV7 potassium channels: a new therapeutic target in smooth muscle disorders

    Stott, J. B., Jepps, Thomas Andrew Qvistgaard & Greenwood, I. A., 12 Dec 2014, In: Drug Discovery Today. 19, 4, p. 413-424 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Vasorelaxant effects of novel Kv7.4 channel enhancers ML213 and NS15370

    Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Stott, J. B., Povstyan, O. V., Sivaloganathan, K., Dalby-Brown, W. & Greenwood, I. A., 9 Jun 2014, In: British Journal of Pharmacology. 171, 19, p. 4413-4424 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity

    Chadha, P. S., Jepps, Thomas Andrew Qvistgaard, Carr, G., Stott, J. B., Zhu, H., Cole, W. C. & Greenwood, I. A., Apr 2014, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 34, 4, p. 887-93 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2013
  24. Published

    Contribution of KV7 Channels to Basal Coronary Flow and Active Response to Ischemia

    Khanamiri, S., Soltysinska, E., Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Chadha, P. S., Schmitt, Nicole, Greenwood, I. A. & Olesen, Søren-Peter, 30 Sep 2013, In: Hypertension. 62, 6, p. 1090-1097 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    One man's side effect is another man's therapeutic opportunity: targeting Kv7 channels in smooth muscle disorders

    Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter & Greenwood, I. A., 2013, In: British Journal of Pharmacology. 168, 1, p. 19-27 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2012
  27. Published

    Pharmacological dissection of K(v)7.1 channels in systemic and pulmonary arteries

    Chadha, P. S., Zunke, F., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Linders, J. T. M., Schwake, M., Towart, R. & Greenwood, I. A., Jun 2012, In: British Journal of Pharmacology. 166, 4, p. 1377-87 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Reduced KCNQ4-encoded voltage-dependent potassium channel activity underlies impaired ß-adrenoceptor-mediated relaxation of renal arteries in hypertension

    Chadha, P. S., Zunke, F., Zhu, H., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Olesen, Søren-Peter, Cole, W. C., Moffatt, J. D. & Greenwood, I., 2012, In: Hypertension. 59, 4, p. 877-84 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2011
  30. Published

    Downregulation of Kv7.4 channel activity in primary and secondary hypertension

    Jepps, Thomas Andrew Qvistgaard, Chadha, P. S., Davis, A. J., Harhun, M. I., Cockerill, G. W., Olesen, S. P., Hansen, R. S. & Greenwood, I. A., 2 Aug 2011, In: Circulation. 124, 5, p. 602-11 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Expression and function of the K+ channel KCNQ genes in human arteries

    Ng, F. L., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Harhun, M. I., Yeung, S. Y., Wan, A., Reddy, M., Melville, D., Nardi, A., Khong, T. K. & Greenwood, I. A., Jan 2011, In: British Journal of Pharmacology. 162, 1, p. 42-53 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2010
  33. Published

    Expression profile and protein translation of TMEM16A in murine smooth muscle

    Davis, A. J., Forrest, A. S., Jepps, Thomas Andrew Qvistgaard, Valencik, M. L., Wiwchar, M., Singer, C. A., Sones, W. R., Greenwood, I. A. & Leblanc, N., Nov 2010, In: A J P: Cell Physiology (Online). 299, 5, p. C948-59

    Research output: Contribution to journalJournal articleResearch

  34. 2009
  35. Published

    Molecular and functional characterization of Kv7 K+ channel in murine gastrointestinal smooth muscles

    Jepps, Thomas Andrew Qvistgaard, Greenwood, I. A., Moffatt, J. D., Sanders, K. M. & Ohya, S., Jul 2009, In: A J P: Gastrointestinal and Liver Physiology (Online). 297, 1, p. G107-15

    Research output: Contribution to journalJournal articleResearch

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