Thomas Andrew Qvistgaard Jepps
Associate Professor
Physiology of circulation, kidney and lung
Blegdamsvej 3
2200 København N.
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4-Aminopyridine: a pan voltage-gated potassium channel inhibitor that enhances K7.4 currents and inhibits noradrenaline-mediated contraction of rat mesenteric small arteries
Khammy, M. M., Kim, S., Bentzen, Bo Hjorth, Lee, S., Choi, I., Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, Feb 2018, In: British Journal of Pharmacology. 175, 3, p. 501-516 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kcne4 deletion sex dependently inhibits the RISK pathway response and exacerbates hepatic ischemia-reperfusion injury in mice
Hu, Z., Jepps, Thomas Andrew Qvistgaard, Zhou, L., Liu, J., Li, M. & Abbott, G. W., 1 May 2019, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 316, 5, p. R552-R562Research output: Contribution to journal › Journal article › Research › peer-review
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Acetaminophen (Paracetamol) Metabolites Induce Vasodilation and Hypotension by Activating Kv7 Potassium Channels Directly and Indirectly
van der Horst, Jennifer, Manville, R. W., Hayes, K., Thomsen, M. B., Abbott, G. W. & Jepps, Thomas Andrew Qvistgaard, 2020, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 40, 5, p. 1207-1219 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute, pro-contractile effects of prorenin on rat mesenteric arteries
Rognant, Salomé, Baldwin, S. N., Pritchard, H. A. T., Greenstein, A., Callø, Kirstine, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2023, In: FASEB Journal. 37, 12, 18 p., e23282.Research output: Contribution to journal › Journal article › Research › peer-review
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Angiotensin II Promotes KV7.4 Channels Degradation Through Reduced Interaction With HSP90 (Heat Shock Protein 90)
Barrese, V., Stott, J. B., Figueiredo, H. B., Aubdool, A. A., Hobbs, A. J., Jepps, Thomas Andrew Qvistgaard, McNeish, A. J. & Greenwood, I. A., Jun 2018, In: Hypertension. 71, 6, p. 1091-1100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Colchicine enhances β adrenoceptor-mediated vasodilation in men with essential hypertension
Ehlers, T. S., van der Horst, Jennifer, Møller, S., Piil, P. K., Gliemann, Lasse, Aalkjær, Christian, Jepps, Thomas Andrew Qvistgaard & Hellsten, Ylva, 2023, In: British Journal of Clinical Pharmacology. 89, 7, p. 2179-2189 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Contractile responses in intact and mucosa-denuded human ureter: a comparison with urinary bladder detrusor preparations
Roedel, M., Ravens, U., Kasper, M., Wirth, M. P., Jepps, Thomas Andrew Qvistgaard & Propping, S., 1 Aug 2018, In: Naunyn-Schmiedeberg's Archives of Pharmacology. 391, 8, p. 773-782 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Contribution of KV7 Channels to Basal Coronary Flow and Active Response to Ischemia
Khanamiri, S., Soltysinska, E., Jepps, Thomas Andrew Qvistgaard, Bentzen, Bo Hjorth, Chadha, P. S., Schmitt, Nicole, Greenwood, I. A. & Olesen, Søren-Peter, 30 Sep 2013, In: Hypertension. 62, 6, p. 1090-1097 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Contribution of Kv7 channels to natriuretic peptide mediated vasodilation in normal and hypertensive rats
Stott, J. B., Barrese, V., Jepps, Thomas Andrew Qvistgaard, Leighton, E. V. & Greenwood, I. A., Mar 2015, In: Hypertension. 65, 3, p. 676-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Contribution of kv7.4/kv7.5 heteromers to intrinsic and calcitonin gene-related Peptide-induced cerebral reactivity
Chadha, P. S., Jepps, Thomas Andrew Qvistgaard, Carr, G., Stott, J. B., Zhu, H., Cole, W. C. & Greenwood, I. A., Apr 2014, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 34, 4, p. 887-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cyclic AMP-Dependent Regulation of Kv7 Voltage-Gated Potassium Channels
van der Horst, Jennifer, Greenwood, I. A. & Jepps, Thomas Andrew Qvistgaard, 2020, In: Frontiers in Physiology. 11, 12 p., 727.Research output: Contribution to journal › Review › Research › peer-review
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Cycling matters: Sex hormone regulation of vascular potassium channels
Baldwin, S. N., Jepps, Thomas Andrew Qvistgaard & Greenwood, I. A., 2023, In: Channels. 17, 1, 19 p., 2217637.Research output: Contribution to journal › Review › Research › peer-review
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Deletion in mice of X-linked, Brugada syndrome- and atrial fibrillation-associated Kcne5 augments ventricular KV currents and predisposes to ventricular arrhythmia
David, J., Lisewski, U., Crump, S. M., Jepps, Thomas Andrew Qvistgaard, Bocksteins, E., Wilck, N., Lossie, J., Roepke, T. K., Schmitt, Nicole & Abbott, G. W., Feb 2019, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 2, p. 2537-2552 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of the first genome-wide significant risk loci for syncope and collapse: [Meeting Abstract]
Ahlberg, G., lvs502, lvs502, Andreasen, L., Hagen, C. M., Ghouse, Jonas, Baekvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Hedley, P., Haunsø, Stig, Svendsen, Jesper Hastrup, Jepps, Thomas Andrew Qvistgaard, Skov, M. W., Christiansen, M. & Olesen, Morten Steen Salling, 2019, In: European Heart Journal. 40, S1, p. 2539-2539 4259 .Research output: Contribution to journal › Conference abstract in journal › Research
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Downregulation of Kv7.4 channel activity in primary and secondary hypertension
Jepps, Thomas Andrew Qvistgaard, Chadha, P. S., Davis, A. J., Harhun, M. I., Cockerill, G. W., Olesen, S. P., Hansen, R. S. & Greenwood, I. A., 2 Aug 2011, In: Circulation. 124, 5, p. 602-11 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynein coordinates β2-adrenoceptor-mediated relaxation in normotensive and hypertensive rat mesenteric arteries
van der Horst, Jennifer, Rognant, Salomé, Hellsten, Ylva, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2022, In: Hypertension. 79, 10, p. 2214-2227 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynein regulates Kv7.4 channel trafficking from the cell membrane
van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.Research output: Contribution to journal › Journal article › Research › peer-review
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Editorial: Kv7 Channels: Structure, Physiology, and Pharmacology
Jepps, Thomas Andrew Qvistgaard, Barrese, V. & Miceli, F., 2021, In: Frontiers in Physiology. 12, 4 p., 679317.Research output: Contribution to journal › Editorial › Research › peer-review
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Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings
Zacharias, T., Flouda, K., Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael J., 2020, In: Biochemical Pharmacology. 173, 14 p., 113631.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression and function of the K+ channel KCNQ genes in human arteries
Ng, F. L., Davis, A. J., Jepps, Thomas Andrew Qvistgaard, Harhun, M. I., Yeung, S. Y., Wan, A., Reddy, M., Melville, D., Nardi, A., Khong, T. K. & Greenwood, I. A., Jan 2011, In: British Journal of Pharmacology. 162, 1, p. 42-53 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression profile and protein translation of TMEM16A in murine smooth muscle
Davis, A. J., Forrest, A. S., Jepps, Thomas Andrew Qvistgaard, Valencik, M. L., Wiwchar, M., Singer, C. A., Sones, W. R., Greenwood, I. A. & Leblanc, N., Nov 2010, In: A J P: Cell Physiology (Online). 299, 5, p. C948-59Research output: Contribution to journal › Journal article › Research
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Functional sympatholysis in mouse skeletal muscle involves sarcoplasmic reticulum swelling in arterial smooth muscle cells
van der Horst, Jennifer, Møller, S., Kjeldsen, Sasha Alexandra Sampson, Wojtaszewski, Jørgen F P, Hellsten, Ylva & Jepps, Thomas Andrew Qvistgaard, 2021, In: Physiological Reports. 9, 23, 10 p., e15133.Research output: Contribution to journal › Journal article › Research › peer-review
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Fundamental role for the KCNE4 ancillary subunit in Kv7.4 regulation of arterial tone
Jepps, Thomas Andrew Qvistgaard, Carr, G., Lundegaard, Pia Rengtved, Olesen, Søren-Peter & Greenwood, I. A., 15 Dec 2015, In: Journal of Physiology. 593, 24, p. 5325-40 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study identifies locus at chromosome 2q32.1 associated with syncope and collapse
lvs502, lvs502, Andreasen, Laura Korsholm, Hagen, C. M., Ahlberg, G., Ghouse, Jonas, Bækvad-Hansen, M., Bybjerg-Grauholm, J., Hougaard, D. M., Hedley, P., Haunsø, Stig, Svendsen, Jesper Hastrup, Kanters, Jørgen K., Jepps, Thomas Andrew Qvistgaard, Skov, M. W., Christiansen, M. & Olesen, Morten Steen Salling, 2020, In: Cardiovascular Research. 116, 1, p. 138-148Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of novel proteins and mechanistic pathways associated with early-onset hypertension by deep proteomic mapping of resistance arteries
Bastrup, Joakim Armstrong, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2022, In: Journal of Biological Chemistry. 298, 1, 17 p., 101512.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 51475012
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MicroRNA-153 targeting of KCNQ4 contributes to vascular dysfunction in hypertension
Research output: Contribution to journal › Journal article › Research › peer-review
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130
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Impaired Kv7 channel function in cerebral arteries of a tauopathy mouse model (rTg4510)
Research output: Contribution to journal › Journal article › Research › peer-review
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93
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Genome-wide association study identifies locus at chromosome 2q32.1 associated with syncope and collapse
Research output: Contribution to journal › Journal article › Research › peer-review
Published