CNS Drug Delivery and Barrier Modelling
Universitetsparken 2, 2100 København Ø, Building: 13-4-417
Primary fields of research
My main research focus is shuttle peptide-mediated drug delivery to the brain. The shuttle peptides include various cell-penetrating- and tight junction-modulating peptides. Subprojects include studies on e.g. pharmacokinetic and pharmacodynamic evaluation in rodents including safety assessment, the mechanism of barrier permeation at the cellular level, and effects of applying various labels to the shuttle peptide for detection and visualization purposes in vitro and in vivo.