René Villadsen
Associate Professor
Morphogenesis and Differentiation Program
Blegdamsvej 3
2200 København N.
- 2024
- Published
Evidence of steady-state fibroblast subtypes in the normal human breast as cells-of-origin for perturbed-state fibroblasts in breast cancer
Bagger, M. M., Sjölund, J., Kim, Jiyoung, Kohler, Katharina Theresa, Villadsen, René, Jafari Kermani, Abbas, Kassem, Moustapha Saad El-Deen, Pietras, K., Rønnov-Jessen, Lone & Petersen, Ole William, 2024, In: Breast Cancer Research. 26, 1, 19 p., 11.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
SSEA-1 Correlates With the Invasive Phenotype in Breast Cancer
Kohler, Katharina Theresa, Møller Hansen, A. A., Kim, Jiyoung & Villadsen, René, 2023, In: Journal of Histochemistry and Cytochemistry. 71, 8, 221554231189312.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Ductal keratin 15+ luminal progenitors in normal breast exhibit a basal-like breast cancer transcriptomic signature
Kohler, Katharina Theresa, Goldhammer, N., Demharter, S., Pfisterer, U., Khodosevich, Konstantin, Rønnov-Jessen, Lone, Petersen, Ole William, Villadsen, René & Kim, Jiyoung, 2022, In: npj Breast Cancer. 8, 1, 12 p., 81.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myoepithelial progenitors as founder cells of hyperplastic human breast lesions upon PIK3CA transformation
Goldhammer, N., Kim, Jiyoung, Villadsen, René, Rønnov-Jessen, Lone & Petersen, Ole William, 2022, In: Communications Biology . 5, 1, 13 p., 219.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus
Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Villadsen, René & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 19 p., 44.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Desensitization of human breast progenitors by a transient exposure to pregnancy levels of estrogen
Rønnov-Jessen, Lone, Kim, Jiyoung, Goldhammer, N., Klitgaard, M. C., Smicius, M., Bechmann, M. B., Villadsen, René & Petersen, Ole William, 2021, In: Scientific Reports. 11, 7 p., 17232.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
AXL Is a Driver of Stemness in Normal Mammary Gland and Breast Cancer
Engelsen, A. S. T., Wnuk-Lipinska, K., Bougnaud, S., Pelissier Vatter, F. A., Tiron, C., Villadsen, R., Miyano, M., Lotsberg, M. L., Madeleine, N., Panahandeh, P., Dhakal, S., Tan, T. Z., Peters, S. D. M., Grøndal, S., Aziz, S. M., Nord, S., Herfindal, L., Stampfer, M. R., Sørlie, T., Brekken, R. A. & 8 others, , 2020, In: iScience. 23, 11, 40 p., 101649.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fibroblasts direct differentiation of human breast epithelial progenitors
Morsing, M., Kim, Jiyoung, Villadsen, René, Goldhammer, N., Jafari Kermani, Abbas, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2020, In: Breast Cancer Research. 22, 16 p., 102.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterogeneity of CEACAM5 in breast cancer
Bechmann, M. B., Brydholm, A. V., Codony, V. L., Kim, Jiyoung & Villadsen, René, 2020, In: OncoTarget. 11, 43, p. 3886-3899 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Expression Pattern of Epidermal Differentiation Marker Keratin 10 in the Normal Human Breast and Breast Cancer Cells
Kim, Jiyoung & Villadsen, René, 2020, In: Journal of Histochemistry and Cytochemistry. 68, 8, p. 561-570Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
A CD146 FACS Protocol Enriches for Luminal Keratin 14/19 Double Positive Human Breast Progenitors
Ísberg, Ó. G., Kim, Jiyoung, Fridriksdottir, A. J., Morsing, M., Timmermans-Wielenga, V., Rønnov-Jessen, Lone, Petersen, Ole William & Villadsen, René, 2019, In: Scientific Reports. 9, 11 p., 14843.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland
Kim, Jiyoung & Villadsen, René, Dec 2018, In: Journal of Histochemistry and Cytochemistry. 66, 12, p. 879-888 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity
Bagger, Sofie Morsing, Hopkinson, B. M., Pandey, D. P., Bak, M., Brydholm, A. V., Villadsen, René, Helin, K., Rønnov-Jessen, Lone, Petersen, Ole William & Kim, Jiyoung, 2018, In: Molecular Cancer. 17, 1, p. 1-6 6 p., 171.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Warburg Effect Metabolism Drives Neoplasia in a Drosophila Genetic Model of Epithelial Cancer
Eichenlaub, T., Villadsen, René, Freitas, F. C. P., Andrejeva, Diana, Aldana, Blanca, Nguyen, H. T., Petersen, Ole William, Gorodkin, Jan, Herranz, Hector & Cohen, S. M., 2018, In: Current Biology. 28, 20, p. 3220-3228.e6Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype
Hopkinson, B. M., Klitgaard, M. C., Petersen, Ole William, Villadsen, René, Rønnov-Jessen, Lone & Kim, Jiyoung, 7 Feb 2017, In: OncoTarget. 8, 6, p. 10580-10593 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proof of region-specific multipotent progenitors in human breast epithelia
Fridriksdottir, A. J., Villadsen, René, Morsing, M., Klitgaard, M. C., Kim, Jiyoung, Petersen, Ole William & Rønnov-Jessen, Lone, 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 47, p. E10102–E10111Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Evidence of two distinct functionally specialized fibroblast lineages in breast stroma
Morsing, M., Klitgaard, M. C., Jafari Kermani, Abbas, Villadsen, René, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2016, In: Breast Cancer Research (Online). 18, 11 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture
Fridriksdóttir, A. J. R., Kim, Jiyoung, Villadsen, René, Klitgaard, M. C., Hopkinson, B. M., Petersen, Ole William & Rønnov-Jessen, Lone, 2015, In: Nature Communications. 6, 12 p., 8786.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
A Marker of Endocrine Receptor-Positive Cells, CEACAM6, Is Shared by Two Major Classes of Breast Cancer: Luminal and HER2-Enriched
Balk-Møller, E., Kim, Jiyoung, Hopkinson, B., Timmermans-Wielenga, V., Petersen, Ole William & Villadsen, René, Apr 2014, In: American Journal of Pathology. 184, 4, p. 1198-1208 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia
Garbe, J. C., Pepin, F., Pelissier, F. A., Sputova, K., Fridriksdottir, A. J., Guo, D. E., Villadsen, René, Park, M., Petersen, Ole William, Borowsky, A. D., Stampfer, M. R. & Labarge, M. A., Jul 2012, In: Cancer Research. 72, 14, p. 3687-701 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells
Vaapil, M., Helczynska, K., Villadsen, René, Petersen, Ole William, Johansson, E., Beckman, S., Larsson, C., Påhlman, S. & Jögi, A., 2012, In: P L o S One. 7, 9, p. e46543Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
Kim, Jiyoung, Villadsen, René, Sørlie, T., Fogh, L., Grønlund, S. Z., Fridriksdóttir, A. J. R., Kuhn, I., Rank, F., Wielenga, V. T., Solvang, H., Edwards, P. A. W., Børresen-Dale, A., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, Ole William, 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 16, p. 6124-6129 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Endothelial induced EMT in breast epithelial cells with stem cell properties
Sigurdsson, V., Hilmarsdottir, B., Sigmundsdottir, H., Fridriksdottir, A. J. R., Ringnér, M., Villadsen, René, Borg, A., Agnarsson, B. A., Petersen, Ole William, Magnusson, M. K. & Gudjonsson, T., 2011, In: P L o S One. 6, 9, p. e23833Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment
De Neergaard, M., Kim, Jiyoung, Villadsen, René, Fridriksdóttir, A. J. R., Rank, F., Timmermans-Wielenga, V., Langerød, A., Børresen-Dale, A., Petersen, Ole William & Rønnov-Jessen, Lone, 2010, In: American Journal of Pathology. 176, 3, p. 1229-1240 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Human mammary progenitor cell fate decisions are productsof interactions with combinatorial microenvironments
LaBarge, M. A., Nelson, C. M., Villadsen, René, Rubner Fridriksdottir, A. J., Ruth, J. R., Stampfer, M. R., Petersen, Ole William & Bissell, M. J., 2009, In: Integrative Biology. 1, p. 70-79 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4354
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Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
242
downloads
Evidence of two distinct functionally specialized fibroblast lineages in breast stroma
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
217
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Warburg Effect Metabolism Drives Neoplasia in a Drosophila Genetic Model of Epithelial Cancer
Research output: Contribution to journal › Journal article › Research › peer-review
Published