Oluf Borbye Pedersen
Visiting professor, Clinical Professor
Pedersen Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal
2200 København N.
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal medicine: infection medicine
Internal Medicine: Endocrinology
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Identification of novel genetic determinants of erythrocyte membrane fatty acid composition among Greenlanders
Lepola, Mette Andersen, Jørsboe, E., Sandholt, C. H., Grarup, Niels, Jørgensen, M. E., Færgeman, N. J., Bjerregaard, P., Pedersen, Oluf Borbye, Moltke, Ida, Hansen, Torben & Albrechtsen, Anders, 2016, In: P L o S Genetics. 12, 6, 19 p., e1006119.Research output: Contribution to journal › Journal article › Research › peer-review
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Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes
Bacos, K., Gillberg, L., Volkov, P., Olsson, A. H., Hansen, Torben, Pedersen, Oluf Borbye, Gjesing, A. M. P., Eiberg, Hans Rudolf Lytchoff, Tuomi, T., Almgren, P., Groop, L., Eliasson, L., Vaag, Allan, Dayeh, T. & Ling, C., 2016, In: Nature Communications. 7, 13 p., 11089.Research output: Contribution to journal › Journal article › Research › peer-review
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An Improved Method for High Quality Metagenomics DNA Extraction from Human and Environmental Samples
Bag, S., Saha, B., Mehta, O., Anbumani, D., Kumar, N., Dayal, M., Pant, A., Kumar, P., Saxena, S., Allin, K. H., Hansen, T., Arumugam, M., Vestergaard, H., Pedersen, O., Pereira, V., Abraham, P., Tripathi, R., Wadhwa, N., Bhatnagar, S., Prakash, V. G. & 7 others, , 2016, In: Scientific Reports. 6, 9 p., 26775.Research output: Contribution to journal › Journal article › Research › peer-review
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Digital questionnaire platform in the Danish Blood Donor Study
Burgdorf, K. S., Felsted, N., Mikkelsen, S., Nielsen, Maria Haahr, Thørner, L. W., Pedersen, Oluf Borbye, Sørensen, E., Nielsen, K. R., Bruun, M. T., Werge, Thomas, Erikstrup, C., Hansen, T. & Ullum, H., 12 Jul 2016, In: Computer Methods and Programs in Biomedicine. 135, p. 101-104 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits
Chami, N., Chen, M-H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L. R., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D. & 93 others, , 7 Jul 2016, In: American Journal of Human Genetics. 99, 1, p. 8-21 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The association between candidate migraine susceptibility loci and severe migraine phenotype in a clinical sample
Esserlind, A., Christensen, A. F., Steinberg, S., Grarup, Niels, Pedersen, Oluf Borbye, Hansen, Torben, Werge, Thomas, Hansen, T. F., Husemoen, L. L. N., Linneberg, Allan René, Budtz-Joergensen, Esben, Westergaard, M. L., Stefansson, H. & Olesen, Jes, 2016, In: Cephalalgia : an international journal of headache. 36, 7, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin Resistance is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation
Faerch, K., Vistisen, D., Pacini, G., Torekov, Signe Sørensen, Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Ahrén, B. & Holst, Jens Juul, 8 Aug 2016, In: Diabetes. 65, 11, p. 3473-3481 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index
Felix, J. F., Bradfield, J. P., Monnereau, C., van der Valk, R. J. P., Stergiakouli, E., Chesi, A., Gaillard, R., Feenstra, B., Thiering, E., Kreiner-Møller, E., Mahajan, A., Pitkänen, N., Joro, R., Cavadino, A., Huikari, V., Franks, S., Groen-Blokhuis, M. M., Cousminer, D. L., Marsh, J. A., Lehtimäki, T. & 31 others, , 2016, In: Human Molecular Genetics. 25, 2, p. 389-403Research output: Contribution to journal › Journal article › Research › peer-review
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The genetic architecture of type 2 diabetes
Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Fernandez Tajes, J., Highland, H. M. & 281 others, , 4 Aug 2016, In: Nature. 536, 7614, p. 41-47 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Years of life gained by multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: 21 years follow-up on the Steno-2 randomised trial
Gæde, P., Øllgaard, J. C., Carstensen, Bendix, Rossing, Peter, Lund-Andersen, H., Parving, H. & Pedersen, Oluf Borbye, Nov 2016, In: Diabetologia. 59, 11, p. 2298-2307 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic investigations of sudden unexpected deaths in infancy using next-generation sequencing of 100 genes associated with cardiac diseases
Hertz, C. L., Christiansen, S. L., Larsen, M. K., Dahl, M., Ferrero-Miliani, L., Weeke, P. E., Pedersen, Oluf Borbye, Hansen, Torben, Grarup, Niels, Ottesen, G. L., Frank-Hansen, R., Banner, Jytte & Morling, Niels, 2016, In: European Journal of Human Genetics. 24, p. 817–822Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide associations for birth weight and correlations with adult disease
Horikoshi, M., Beaumont, R. N., Day, F. R., Warrington, N. M., Kooijman, M. N., Fernandez-Tajes, J., Feenstra, B., van Zuydam, N. R., Gaulton, K. J., Grarup, N., Bradfield, J. P., Strachan, D. P., Li-Gao, R., Ahluwalia, T. V. S., Kreiner, E., Rueedi, R., Lyytikäinen, L-P., Cousminer, D. L., Wu, Y., Thiering, E. & 31 others, , 28 Sep 2016, In: Nature. 538, p. 248-252 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Mendelian randomisation study of the associations of vitamin B12 and folate genetic risk scores with blood pressure and fasting serum lipid levels in three Danish population-based studies
Husemoen, L. L. N., Skaaby, T., Thuesen, B. H., Grarup, Niels, Sandholt, C. H., Hansen, Torben, Pedersen, Oluf Borbye & Linneberg, Allan René, 24 Feb 2016, In: European Journal of Clinical Nutrition. 70, p. 613-619 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes
Imamura, M., Takahashi, A., Yamauchi, T., Hara, K., Yasuda, K., Grarup, N., Zhao, W., Wang, X., Huerta-Chagoya, A., Hu, C., Moon, S., Long, J., Kwak, S. H., Rasheed, A., Saxena, R., Ma, R. C. W., Okada, Y., Iwata, M., Hosoe, J., Shojima, N. & 43 others, , 2016, In: Nature Communications. 7, 12 p., 10531.Research output: Contribution to journal › Journal article › Research › peer-review
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Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years
Justesen, Johanne Marie, Andersson, E. A., Allin, K. H., Sandholt, C. H., Jørgensen, T., Linneberg, Allan René, Jørgensen, M. E., Hansen, Torben, Pedersen, Oluf Borbye & Grarup, Niels, Dec 2016, In: Journal of Lipid Research. 57, 12, p. 2193-2199 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels
Kilpeläinen, T. O., Carli, J. F. M., Skowronski, A. A., Sun, Q., Kriebel, J., Feitosa, M. F., Hedman, Å. K., Drong, A. W., Hayes, J. E., Zhao, J., Pers, T. H., Schick, U., Grarup, N., Kutalik, Z., Trompet, S., Mangino, M., Kristiansson, K., Beekman, M., Lyytikäinen, L-P., Eriksson, J. & 157 others, , 2016, In: Nature Communications. 7, 14 p., 10494.Research output: Contribution to journal › Journal article › Research › peer-review
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Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: a systematic review of randomized controlled trials
Kristensen, N. B., Bryrup, T., Allin, K. H., Nielsen, T., Hansen, T. H. & Pedersen, Oluf Borbye, 2016, In: Genome Medicine. 8, 1, 11 p., 52.Research output: Contribution to journal › Journal article › Research › peer-review
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Serum 25-Hydroxyvitamin D Status and Longitudinal Changes in Weight and Waist Circumference: Influence of Genetic Predisposition to Adiposity
Larsen, S. C., Ängquist, Lars, Moldovan, M., Huikari, V., Sebert, S., Cavadino, A., Ahluwalia, Tarun Veer Singh, Skaaby, T., Linneberg, Allan René, Husemoen, L. L. N., Toft, U., Pedersen, Oluf Borbye, Hansen, T., Herzig, K., Jarvelin, M., Power, C., Hypponen, E., Heitmann, Berit & Sørensen, Thorkild I.A., 14 Apr 2016, In: P L o S One. 11, 4, p. 1-18 e0153611.Research output: Contribution to journal › Journal article › Research › peer-review
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Reference values for serum leptin in healthy non-obese children and adolescents
Lausten-Thomsen, U., Christiansen, M., Louise Hedley, P., Fonvig, C. E., Stjernholm, T., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2016, In: Scandinavian Journal of Clinical & Laboratory Investigation. 76, 7, p. 561-567 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma alkylresorcinols reflect gluten intake and distinguish between gluten-rich and gluten-poor diets in a population at risk of metabolic syndrome
Lind, M. V., Madsen, M. L., Rumessen, J. J., drb459, drb459, Gøbel, R. J., Hansen, Torben, Lauritzen, Lotte, Pedersen, Oluf Borbye, Kristensen, M. B. & Ross, A. B., 2016, In: Journal of Nutrition. 146, 10, p. 1991-1998 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FTO genotype and weight loss: systematic review and meta-analysis of 9563 individual participant data from eight randomised controlled trials
Livingstone, K. M., Celis-Morales, C., Papandonatos, G. D., Erar, B., Florez, J. C., Jablonski, K. A., Razquin, C., Marti, A., Heianza, Y., Huang, T., Sacks, F. M., Svendstrup, M., Sui, X., Church, T. S., Jääskeläinen, T., Lindström, J., Tuomilehto, J., Uusitupa, M., Rankinen, T., Saris, W. H. M. & 12 others, , 2016, In: B M J. 354, 11 p., i4707.Research output: Contribution to journal › Journal article › Research › peer-review
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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, Å. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S. & 239 others, , 1 Feb 2016, In: Nature Communications. 7, p. 1-15 15 p., 10495.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of biphasic, basal-bolus or basal insulin analogue treatments on carotid intima-media thickness in patients with type 2 diabetes mellitus: the randomised Copenhagen Insulin and Metformin Therapy (CIMT) trial
Lundby-Christensen, L., Vaag, A., Tarnow, L., Almdal, T. P., Lund, S. S., Wetterslev, J., Gluud, C., Boesgaard, T. W., Wiinberg, N., Perrild, H., Krarup, T., Snorgaard, O., Gade-Rasmussen, B., Thorsteinsson, B., Røder, M., Mathiesen, E. R., Jensen, T., Vestergaard, H., Hedetoft, C., Breum, L. & 6 others, , 2016, In: B M J Open. 6, 2, e008377.Research output: Contribution to journal › Journal article › Research › peer-review
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Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus: the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial
Lundby-Christensen, L., Tarnow, L., Boesgaard, T. W., Lund, S. S., Wiinberg, N., Perrild, H., Krarup, T., Snorgaard, O., Gade-Rasmussen, B., Thorsteinsson, B., Røder, M., Mathiesen, E. R., Jensen, T., Vestergaard, H., Hedetoft, C., Breum, L., Duun, E., Sneppen, S. B., Pedersen, O., Hemmingsen, B. & 6 others, , 2016, In: B M J Open. 6, 2, e008376.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Human Intestinal Microbiome in Health and Disease
Lynch, S. V. & Pedersen, Oluf Borbye, 15 Dec 2016, In: New England Journal of Medicine. 375, 24, p. 2369-2379 11 p.Research output: Contribution to journal › Review › Research › peer-review
ID: 919113
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5479
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Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Research output: Contribution to journal › Journal article › Research › peer-review
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5233
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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
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4516
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Research output: Contribution to journal › Journal article › Research › peer-review
Published