Oluf Borbye Pedersen
Visiting professor, Clinical Professor
Pedersen Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal
2200 København N.
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal medicine: infection medicine
Internal Medicine: Endocrinology
- Published
Effects of hyperinsulinemia and hyperglycemia on insulin receptor function and glycogen synthase activation in skeletal muscle of normal man
Bak, J. F., Møller, N., Schmitz, O., Richter, Erik A. & Pedersen, Oluf Borbye, 1991, In: Metabolism. 40, 8, p. 830-835 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevation of serum insulin concentration during euglycemic hyperinsulinemic clamp studies leads to similar activation of insulin receptor kinase in skeletal muscle of subjects with and without NIDDM
Klein, H. H., drb459, drb459, Kotzke, G. & Pedersen, Oluf Borbye, Nov 1995, In: Diabetes. 44, 11, p. 1310-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations
Benzinou, M., Chèvre, J., Ward, K. J., Lecoeur, C., Dina, C., Lobbens, S., Durand, E., Delplanque, J., Horber, F. F., Heude, B., Balkau, B., Borch-Johnsen, K., Jørgensen, T., Hansen, T., Pedersen, Oluf Borbye, Meyre, D. & Froguel, P., 2008, In: Human Molecular Genetics. 17, 13, p. 1916-21 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum
Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J-M., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, T., Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K. & 31 others, , 2011, In: Nature. 473, 7346, p. 174-180 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Environmental spread of microbes impacts the development of metabolic phenotypes in mice transplanted with microbial communities from humans
Zhang, L., Bahl, M. I., Roager, Henrik Munch, Fonvig, C. E., Hellgren, L. I., Frandsen, H. L., Pedersen, Oluf Borbye, Holm, Jens-Christian, Hansen, Torben & Licht, T. R., 18 Nov 2017, In: The ISME Journal. 11, p. 676-690 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimates of insulin sensitivity and β-cell function in children and adolescents with and without components of the metabolic syndrome
Frithioff-Bøjsøe, C., Trier, C., Fonvig, Cilius Esmann, Nissen, A., Kloppenborg, J. T., Mollerup, P. M., Bjerrum, P. J., Pedersen, Oluf Borbye, Hansen, Torben & Holm, Jens-Christian, 2017, In: Pediatric Endocrinology, Diabetes and Metabolism. 23, 3, p. 122-129 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimating the causal effect of body mass index on hay fever, asthma and lung function using Mendelian randomization
Skaaby, T., Taylor, A. E., Thuesen, B. H., Jacobsen, R. K., Friedrich, N., Møllehave, L. T., Hansen, S., Larsen, S. C., Völker, U., Nauck, M., Völzke, H., Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T., Paternoster, L., Munafò, M., Grarup, Niels & Linneberg, Allan René, 2018, In: Allergy. 73, 1, p. 153-164 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimation of allele frequency and association mapping using next-generation sequencing data
Kim, S. Y., Lohmueller, K. E., Albrechtsen, Anders, Li, Y., Korneliussen, Thorfinn Sand, Tian, G., Grarup, Niels, Jiang, T., Andersen, G., Witte, D., Jorgensen, T., Hansen, Torben, Pedersen, Oluf Borbye, Wang, J. & Nielsen, Rasmus, 2011, In: B M C Bioinformatics. 12, p. 231 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model
Gao, R., Liu, Y., Gjesing, A. M. P., Hollensted, M., Wan, X., He, S., Pedersen, Oluf Borbye, Yi, X., Wang, J. & Hansen, Torben, 2014, In: B M C Genetics. 15, 9 p., 13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for an association between the Leu162Val polymorphism of the PPARalpha gene and decreased fasting serum triglyceride levels in glucose tolerant subjects
Nielsen, E. D., Hansen, L., Echwald, S. M., Drivsholm, Thomas, Borch-Johnsen, K., Ekstrøm, C. T., Hansen, Torben & Pedersen, Oluf Borbye, 2003, In: Pharmacogenetics and Genomics. 13, 7, p. 417-23 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide
Andrikopoulos, P., Aron-Wisnewsky, J., Chakaroun, R., Myridakis, A., Forslund, S. K., Nielsen, T., Adriouch, S., Holmes, B., Chilloux, J., Vieira-Silva, S., Falony, G., Salem, J. E., Andreelli, F., Belda, E., Kieswich, J., Chechi, K., Puig-Castellvi, F., Chevalier, M., Le Chatelier, E., Olanipekun, M. T. & 83 others, , 2023, In: Nature Communications. 14, 18 p., 5843.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids
Albrechtsen, Nicolai Jacob Wewer, Færch, K., Jensen, T. M., Witte, D. R., Pedersen, Jens, Mahendran, Y., Jonsson, Anna Elisabet, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Torekov, Signe Sørensen, Lauritzen, T., Pedersen, Oluf Borbye, Knop, Filip Krag, Hansen, Torben, Jørgensen, M. E., Vistisen, D. & Holst, Jens Juul, 2018, In: Diabetologia. 61, 3, p. 671-680Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes
Torekov, Signe Sørensen, Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Diabetes. 54, 7, p. 2261-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene
hart, L. M., Hansen, Torben, Rietveld, I., Dekker, J. M., Nijpels, G., Janssen, G. M. C., Arp, P. A., Uitterlinden, A. G., Jørgensen, T., Borch-Johnsen, K., Pols, H. A. P., Pedersen, Oluf Borbye, van Duijn, C. M., Heine, R. J. & Maassen, J. A., 2005, In: Diabetes. 54, 6, p. 1892-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits
Chami, N., Chen, M-H., Slater, A. J., Eicher, J. D., Evangelou, E., Tajuddin, S. M., Love-Gregory, L., Kacprowski, T., Schick, U. M., Nomura, A., Giri, A., Lessard, S., Brody, J. A., Schurmann, C., Pankratz, N., Yanek, L. R., Manichaikul, A., Pazoki, R., Mihailov, E., Hill, W. D. & 93 others, , 7 Jul 2016, In: American Journal of Human Genetics. 99, 1, p. 8-21 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
Broad Genomics Platform, B. G. P., Jun 2019, In: Nature. 570, 7759, p. 71-76 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes
Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T. H., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T. S., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stancáková, A., Andersen, G., Astrup, A., Banasik, K. & 86 others, , 2013, In: Diabetologia. 56, 2, p. 298-310 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6
Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., Li-Gao, R. & 31 others, , 17 Jul 2018, In: Genome Biology. 19, 17 p., 87.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome-wide association study of plasma lipids in >300,000 individuals
Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 208 others, , 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals
Bihlmeyer, N. A., Brody, J. A., Smith, A. V., Warren, H. R., Lin, H., Isaacs, A., Liu, C-T., Marten, J., Radmanesh, F., Hall, L. M., Grarup, N., Mei, H., Muller-Nurasyid, M., Huffman, J. E., Verweij, N., Guo, X., Yao, J., Li-Gao, R., van den Berg, M., Weiss, S. & 30 others, , 2018, In: Circulation. Genomic and precision medicine. 11, 1, p. 1-10 e001758.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure to environmental toxicants is associated with gut microbiome dysbiosis, insulin resistance and obesity
Sen, P., Fan, Yong, Schlezinger, J. J., Ehrlich, S. D., Webster, T. F., Hyötyläinen, T., Pedersen, Oluf Borbye & Orešič, M., 2024, In: Environment International. 186, 12 p., 108569.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of glycogen synthase and phosphofructokinase in muscle from type 1 (insulin-dependent) diabetic patients before and after intensive insulin treatment
drb459, drb459, Andersen, P. H., Lund, S., Vedel, P. & Pedersen, Oluf Borbye, Jan 1994, In: Diabetologia. 37, 1, p. 82-90 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus
Hansen, Torben, Bjørbaek, C., drb459, drb459, Grønskov, K., Bak, J. F. & Pedersen, Oluf Borbye, Dec 1993, In: The Journal of clinical endocrinology and metabolism. 77, 6, p. 1500-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of protein-tyrosine phosphatases in the major insulin target tissues
Norris, K., Norris, F., Kono, D. H., drb459, drb459, Pedersen, Oluf Borbye, Theofilopoulos, A. N. & Møller, N. P., 6 Oct 1997, In: FEBS Letters. 415, 3, p. 243-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression profiling of insulin action in human myotubes: induction of inflammatory and pro-angiogenic pathways in relationship with glycogen synthesis and type 2 diabetes
Hansen, L., Gaster, M., Oakeley, E. J., Brusgaard, K., Damsgaard Nielsen, E., Beck-Nielsen, H., Pedersen, Oluf Borbye & Hemmings, B. A., 2004, In: Biochemical and Biophysical Research Communications. 323, 2, p. 685-95 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 919113
Most downloads
-
5481
downloads
Natural selection affects multiple aspects of genetic variation at putatively peutral sites across the human genome
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
5235
downloads
Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
4519
downloads
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Research output: Contribution to journal › Journal article › Research › peer-review
Published