Oluf Borbye Pedersen

Gut microbiota in human metabolic health and disease

Fan, Yong & Pedersen, Oluf Borbye, 2021, In: Nature Reviews. Microbiology. 19, p. 55-71 17 p.

Research output: Contribution to journal › Review › Research › peer-review

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Goodrich, J. K., Singer-Berk, M., Son, R., Sveden, A., Wood, J., England, E., Cole, J. B., Weisburd, B., Watts, N., Caulkins, L., Dornbos, P., Koesterer, R., Zappala, Z., Zhang, H., Maloney, K. A., Dahl, A., Aguilar-Salinas, C. A., Atzmon, G., Barajas-Olmos, F., Barzilai, N. & 31 others, Blangero, J., Boerwinkle, E., Bonnycastle, L. L., Bottinger, E., Bowden, D. W., Centeno-Cruz, F., Chambers, J. C., Chami, N., Chan, E., Chan, J., Cheng, C. Y., Cho, Y. S., Contreras-Cubas, C., Córdova, E., Correa, A., DeFronzo, R. A., Duggirala, R., Dupuis, J., Garay-Sevilla, M. E., García-Ortiz, H., Gieger, C., Glaser, B., González-Villalpando, C., Gonzalez, M. E., Grarup, Niels, Groop, L., Gross, M., Hansen, Torben, Linneberg, Allan René, Pedersen, Oluf Borbye & AMP-T2D-GENES Consortia, A. C., 2021, In: Nature Communications. 12, 15 p., 3505.

Research output: Contribution to journal › Journal article › Research › peer-review

The power of genetic diversity in genome-wide association studies of lipids

Graham, S. E., Clarke, S. L., Wu, K-H. H., Kanoni, S., Zajac, G. J. M., Ramdas, S., Surakka, I., Ntalla, I., Vedantam, S., Winkler, T. W., Locke, A. E., Marouli, E., Hwang, M. Y., Han, S., Narita, A., Choudhury, A., Bentley, A. R., Ekoru, K., Verma, A., Trivedi, B. & 504 others, Martin, H. C., Hunt, K. A., Hui, Q., Klarin, D., Zhu, X., Thorleifsson, G., Helgadottir, A., Gudbjartsson, D. F., Holm, H., Olafsson, I., Akiyama, M., Sakaue, S., Terao, C., Kanai, M., Zhou, W., Brumpton, B. M., Rasheed, H., Ruotsalainen, S. E., Havulinna, A. S., Veturi, Y., Feng, Q., Rosenthal, E. A., Lingren, T., Pacheco, J. A., Pendergrass, S. A., Haessler, J., Giulianini, F., Bradford, Y., Miller, J. E., Campbell, A., Lin, K., Millwood, I. Y., Hindy, G., Rasheed, A., Faul, J. D., Zhao, W., Weir, D. R., Turman, C., Huang, H., Graff, M., Mahajan, A., Brown, M. R., Zhang, W., Yu, K., Schmidt, E. M., Pandit, A., Gustafsson, S., Yin, X., Luan, J., Zhao, J., Matsuda, F., Jang, H., Yoon, K., Medina-Gomez, C., Pitsillides, A., Hottenga, J. J., Willemsen, G., Wood, A. R., Ji, Y., Gao, Z., Haworth, S., Mitchell, R. E., Chai, J. F., Aadahl, Mette, Yao, J., Manichaikul, A., Warren, H. R., Ramirez, J., Bork-Jensen, J., Karhus, L. L., Goel, A., Sabater-Lleal, M., Noordam, R., Sidore, C., Fiorillo, E., McDaid, A. F., Marques-Vidal, P., Wielscher, M., Trompet, S., Sattar, N., Møllehave, Line Tang, Thuesen, B. H., Munz, M., Zeng, L., Huang, J., Yang, B., Poveda, A., Kurbasic, A., Lamina, C., Forer, L., Scholz, M., Galesloot, T. E., Bradfield, J. P., Daw, E. W., Zmuda, J. M., Mitchell, J. S., Fuchsberger, C., Christensen, H., Brody, J. A., Feitosa, M. F., Wojczynski, M. K., Preuss, M., Mangino, M., Christofidou, P., Verweij, N., Benjamins, J. W., Engmann, J., Kember, R. L., Slieker, R. C., Lo, K. S., Zilhao, N. R., Phuong Le, Kleber, M. E., Delgado, G. E., Huo, S., Ikeda, D. D., Iha, H., Yang, J., Liu, J., Leonard, H. L., Marten, J., Schmidt, B., Arendt, M., Smyth, L. J., Canadas-Garre, M., Wang, C., Nakatochi, M., Wong, A., Hutri-Kahonen, N., Sim, X., Xia, R., Huerta-Chagoya, A., Fernandez-Lopez, J. C., Lyssenko, V., Ahmed, M., Jackson, A. U., Irvin, M. R., Oldmeadow, C., Kim, H., Ryu, S., Timmers, P. R. H. J., Arbeeva, L., Dorajoo, R., Lange, L. A., Chai, X., Prasad, G., Lores-Motta, L., Pauper, M., Long, J., Li, X., Theusch, E., Takeuchi, F., Spracklen, C. N., Loukola, A., Bollepalli, S., Warner, S. C., Wang, Y. X., Wei, W. B., Nutile, T., Ruggiero, D., Sung, Y. J., Hung, Y., Chen, S., Liu, F., Yang, J., Kentistou, K. A., Gorski, M., Brumat, M., Meidtner, K., Bielak, L. F., Smith, J. A., Hebbar, P., Farmaki, A., Hofer, E., Lin, M., Xue, C., Zhang, J., Concas, M. P., Vaccargiu, S., van der Most, P. J., Pitkanen, N., Cade, B. E., Lee, J., van Der Laan, S. W., Chitrala, K. N., Weiss, S., Zimmermann, M. E., Lee, J. Y., Choi, H. S., Nethander, M., Freitag-Wolf, S., Southam, L., Rayner, N. W., Wang, C. A., Lin, S., Wang, J., Couture, C., Lyytikainen, L., Nikus, K., Cuellar-Partida, G., Vestergaard, H., Hildalgo, B., Giannakopoulou, O., Cai, Q., Obura, M. O., van Setten, J., Li, X., Schwander, K., Terzikhan, N., Shin, J. H., Jackson, R. D., Reiner, A. P., Martin, L. W., Chen, Z., Li, L., Highland, H. M., Young, K. L., Kawaguchi, T., Thiery, J., Bis, J. C., Nadkarni, G. N., Launer, L. J., Li, H., Nalls, M. A., Raitakari, O. T., Ichihara, S., Wild, S. H., Nelson, C. P., Campbell, H., Jager, S., Nabika, T., Al-Mulla, F., Niinikoski, H., Braund, P. S., Kolcic, I., Kovacs, P., Giardoglou, T., Katsuya, T., Bhatti, F., de Kleijn, D., de Borst, G. J., Kim, E. K., Adams, H. H. H., Ikram, M. A., Zhu, X., Asselbergs, F. W., Kraaijeveld, A. O., Beulens, J. W. J., Shu, X., Rallidis, L. S., Pedersen, Oluf Borbye, Hansen, Torben, Mitchell, P., Hewitt, A. W., Kahonen, M., Perusse, L., Bouchard, C., Tonjes, A., Chen, Y. I., Pennell, C. E., Mori, T. A., Lieb, W., Franke, A., Ohlsson, C., Mellstrom, D., Cho, Y. S., Lee, H., Yuan, J., Koh, W., Rhee, S. Y., Woo, J., Heid, I. M., Stark, K. J., Volzke, H., Homuth, G., Evans, M. K., Zonderman, A. B., Polasek, O., Pasterkamp, G., Hoefer, I. E., Redline, S., Pahkala, K., Oldehinkel, A. J., Snieder, H., Biino, G., Schmidt, R., Schmidt, H., Chen, Y. E., Bandinelli, S., Dedoussis, G., Thanaraj, T. A., Kardia, S. L. R., Kato, N., Schulze, M. B., Girotto, G., Jung, B., Boger, C. A., Joshi, P. K., Bennett, D. A., De Jager, P. L., Lu, X., Mamakou, V., Brown, M., Caulfield, M. J., Munroe, P. B., Guo, X., Ciullo, M., Jonas, J. B., Samani, N. J., Kaprio, J., Pajukanta, P., Adair, L. S., Bechayda, S. A., de Silva, H. J., Wickremasinghe, A. R., Krauss, R. M., Wu, J., Zheng, W., den Hollander, A. I., Bharadwaj, D., Correa, A., Wilson, J. G., Lind, L., Heng, C., Nelson, A. E., Golightly, Y. M., Wilson, J. F., Penninx, B., Kim, H., Attia, J., Scott, R. J., Rao, D. C., Arnett, D. K., Walker, M., Koistinen, H. A., Chandak, G. R., Yajnik, C. S., Mercader, J. M., Tusie-Luna, T., Aguilar-Salinas, C. A., Villalpando, C. G., Orozco, L., Fornage, M., Tai, E. S., van Dam, R. M., Lehtimaki, T., Chaturvedi, N., Yokota, M., Liu, J., Reilly, D. F., McKnight, A. J., Kee, F., Jockel, K., McCarthy, M. I., Palmer, C. N. A., Vitart, V., Hayward, C., Simonsick, E., van Duijn, C. M., Lu, F., Qu, J., Hishigaki, H., Lin, X., Marz, W., Parra, E. J., Cruz, M., Gudnason, V., Tardif, J., Lettre, G., 't Hart, L. M., Elders, P. J. M., Damrauer, S. M., Kumari, M., Kivimaki, M., van der Harst, P., Spector, T. D., Loos, R. J. F., Province, M. A., Psaty, B. M., Brandslund, I., Pramstaller, P. P., Christensen, K., Ripatti, S., Widen, E., Hakonarson, H., Grant, S. F. A., Kiemeney, L. A. L. M., de Graaf, J., Loeffler, M., Kronenberg, F., Gu, D., Erdmann, J., Schunkert, H., Franks, P. W., Linneberg, Allan René, Jukema, J. W., Khera, A. V., Mannikko, M., Jarvelin, M., Kutalik, Z., Cucca, F., Mook-Kanamori, D. O., van Dijk, K. W., Watkins, H., Strachan, D. P., Grarup, Niels, Sever, P., Poulter, N., Rotter, J. I., Dantoft, T. M., Karpe, F., Neville, M. J., Timpson, N. J., Cheng, C., Wong, T., Khor, C. C., Sabanayagam, C., Peters, A., Gieger, C., Hattersley, A. T., Pedersen, N. L., Magnusson, P. K. E., Boomsma, D. I., de Geus, E. J. C., Cupples, L. A., van Meurs, J. B. J., Ghanbari, M., Rsen, P. G., Huang, W., Kim, Y. J., Tabara, Y., Wareham, N. J., Langenberg, C., Zeggini, E., Kuusisto, J., Laakso, M., Ingelsson, E., Abecasis, G., Chambers, J. C., Kooner, J. S., de Vries, P. S., Morrison, A. C., North, K. E., Daviglus, M., Kraft, P., Martin, N. G., Whitfield, J. B., Abbas, S., Saleheen, D., Walters, R. G., Holmes, M. V., Black, C., Smith, B. H., Justice, A. E., Baras, A., Buring, J. E., Ridker, P. M., Chasman, D. I., Kooperberg, C., Wei, W., Jarvik, G. P., Namjou, B., Hayes, M. G., Ritchie, M. D., Jousilahti, P., Salomaa, V., Hveem, K., Asvold, B. O., Kubo, M., Kamatani, Y., Okada, Y., Murakami, Y., Thorsteinsdottir, U., Stefansson, K., Ho, Y., Lynch, J. A., Rader, D. J., Tsao, P. S., Chang, K., Cho, K., O'Donnell, C. J., Gaziano, J. M., Wilson, P., Rotimi, C. N., Hazelhurst, S., Ramsay, M., Trembath, R. C., van Heel, D. A., Tamiya, G., Yamamoto, M., Kim, B., Mohlke, K. L., Frayling, T. M., Hirschhorn, J. N., Kathiresan, S., Boehnke, M., Natarajan, P., Peloso, G. M., Brown, C. D., Morris, A. P., Assimes, T. L., Deloukas, P., Sun, Y. V. & Willer, C. J., 2021, In: Nature. 600, p. 675-679

Research output: Contribution to journal › Journal article › Research › peer-review

Genome-wide association study of circulating levels of glucagon during an oral glucose tolerance test

Jonsson, Anna Elisabet, Stinson, Sara, Torekov, Signe Sørensen, Clausen, Tine Dalsgaard, Færch, K., Kelstrup, Louise, Grarup, Niels, Mathiesen, Elisabeth, Damm, Peter, Witte, D. R., Jørgensen, M. E., Pedersen, Oluf Borbye, Holst, Jens Juul & Hansen, Torben, 2021, In: BMC Medical Genomics. 14, 7 p., 3.

Research output: Contribution to journal › Journal article › Research › peer-review

Large-scale association analyses identify host factors influencing human gut microbiome composition

Kurilshikov, A., Medina-Gomez, C., Bacigalupe, R., Radjabzadeh, D., Wang, J., Demirkan, A., Le Roy, C. I., Raygoza Garay, J. A., Finnicum, C. T., Liu, X., Zhernakova, D. V., Bonder, M. J., Hansen, T. H., Frost, F., Rühlemann, M. C., Turpin, W., Moon, J. Y., Kim, H. N., Lüll, K., Barkan, E. & 84 others, Shah, S. A., Fornage, M., Szopinska-Tokov, J., Wallen, Z. D., Borisevich, D., Agreus, L., Andreasson, A., Bang, C., Bedrani, L., Bell, J. T., Bisgaard, H., Boehnke, M., Boomsma, D. I., Burk, R. D., Claringbould, A., Croitoru, K., Davies, G. E., van Duijn, C. M., Duijts, L., Falony, G., Fu, J., van der Graaf, A., Hansen, Torben, Homuth, G., Hughes, D. A., Ijzerman, R. G., Jackson, M. A., Jaddoe, V. W. V., Joossens, M., Jørgensen, T., Keszthelyi, D., Knight, R., Laakso, M., Laudes, M., Launer, L. J., Lieb, W., Lusis, A. J., Masclee, A. A. M., Moll, H. A., Mujagic, Z., Qibin, Q., Rothschild, D., Shin, H., Sørensen, Søren Johannes, Steves, C. J., Thorsen, Jonathan Jan Ilve, Timpson, N. J., Tito, R. Y., Vieira-Silva, S., Völker, U., Völzke, H., Võsa, U., Wade, K. H., Walter, S., Watanabe, K., Weiss, S., Weiss, F. U., Weissbrod, O., Westra, H. J., Willemsen, G., Payami, H., Jonkers, D. M. A. E., Arias Vasquez, A., de Geus, E. J. C., Meyer, K. A., Stokholm, Jakob, Segal, E., Org, E., Wijmenga, C., Kim, H. L., Kaplan, R. C., Spector, T. D., Uitterlinden, A. G., Rivadeneira, F., Franke, A., Lerch, M. M., Franke, L., Sanna, S., D’Amato, M., Pedersen, Oluf Borbye, Paterson, A. D., Kraaij, R., Raes, J. & Zhernakova, A., 2021, In: Nature Genetics. 53, p. 156-165 19 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Superficial fungal infections and patients with hidradenitis suppurativa: a study under the Danish Blood Donor Study

Lindso Andersen, P., Andersen, Rune Kjærsgaard, Jemec, Gregor, Ullum, H., Erikstrup, C., Nielsen, K. R., Bruun, M. T., Hjalgrim, Henrik, Sørensen, E., Burgdorf, K. S., Dinh, K. M., Banasik, Karina, Hansen, T., Saunte, Ditte Marie & Pedersen, Oluf Borbye, 2021, In: Clinical and Experimental Dermatology. 46, 3, p. 571-573 3 p.

Research output: Contribution to journal › Letter › Research › peer-review

Author's reply to Kahn's comment

Møller, G., Ritz, C., Kjølbæk, Louise, Vuholm, S., Korndal, S. K., Larsen, T. M., Pedersen, Oluf Borbye, Saris, W. H., Astrup, A., Lauritzen, Lotte, Kristensen, M. B. & Lind, M. V., 2021, In: Nutrition, Metabolism & Cardiovascular Diseases. 31, 6, p. 1940-1941 2 p.

Research output: Contribution to journal › Comment/debate › Research

Sagittal abdominal diameter and waist circumference appear to be equally good as identifiers of cardiometabolic risk

Møller, G., Ritz, C., Kjølbæk, Louise, Vuholm, S., Korndal, S. K., Larsen, T. M., Pedersen, Oluf Borbye, Saris, W. H., Astrup, A., Lauritzen, Lotte, Kristensen, M. B. & Lind, M. V., 2021, In: Nutrition, Metabolism & Cardiovascular Diseases. 31, 2, p. 518-527 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Conjugated C-6 hydroxylated bile acids in serum relate to human metabolic health and gut Clostridia species

Petersen, A. Ø., Julienne, H., Hyötyläinen, T., Sen, P., Fan, Yong, Pedersen, H. K., Jäntti, S., Hansen, T. H., Nielsen, T., Jørgensen, T., Hansen, Torben, Myers, P. N., Nielsen, H. B., Ehrlich, S. D., Orešič, M. & Pedersen, Oluf Borbye, 2021, In: Scientific Reports. 11, 1, 11 p., 13252.

Research output: Contribution to journal › Journal article › Research › peer-review

Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark

Pinna, N. K., Anjana, R. M., Saxena, S., Dutta, A., Gnanaprakash, V., Rameshkumar, G., Aswath, S., Raghavan, S., Rani, C. S. S., Radha, V., Balasubramanyam, M., Pant, A., Nielsen, T., Jørgensen, T., Færch, K., Kashani, A., Silva, M. C. A., Vestergaard, H., Hansen, T. H., Hansen, T. & 6 others, Arumugam, Mani, Nair, G. B., Das, B., Pedersen, Oluf Borbye, Mohan, V. & Mande, S. S., 2021, In: Genome Medicine. 13, 20 p., 36.

Research output: Contribution to journal › Journal article › Research › peer-review