Niels Johan Christensen

Niels Johan Christensen

Guest Researcher


  1. 2023
  2. Published

    Ca2+-Responsive Glyco-insulin

    Wu, S., Østergaard, M., Fredholt, Freja, Christensen, Niels Johan, Sørensen, K. K., Mishra, N. K., Nielsen, Hanne Mørck & Jensen, Knud Jørgen, 2023, In: Bioconjugate Chemistry. 34, 3, p. 518–528

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2022
  4. Published

    Chirality transmission in macromolecular domains

    Pandey, S., Mandal, S., Danielsen, M. B., Brown, A., Hu, C., Christensen, Niels Johan, Kulakova, A. V., Song, S., Brown, T., Jensen, Knud Jørgen, Wengel, J., Lou, C. & Mao, H., 2022, In: Nature Communications. 13, 1, 11 p., 76.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Identifying interactions in omics data for clinical biomarker discovery using symbolic regression

    Christensen, Niels Johan, Demharter, S., Machado, M., Pedersen, L., Salvatore, M., Stentoft-Hansen, V. & Iglesias, M. T., 2022, In: Bioinformatics. 38, 15, p. 3749-3758 10 p., 405.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Tying Up a Loose End: On the Role of the C-Terminal CCHHRAG Fragment of the Metalloregulator CueR

    Balogh, R. K., Gyurcsik, B., Jensen, M., Thulstrup, Peter Waaben, Koester, U., Christensen, Niels Johan, Jensen, Marianne Lund, Hunyadi-Gulyas, E., Hemmingsen, Lars Bo Stegeager & Jancso, A., 2022, In: ChemBioChem. 23, 16, 9 p., 202200290.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2021
  8. Published

    Controlling the fractal dimension in self-assembly of terpyridine modified insulin by Fe2+ and Eu3+ to direct in vivo effects

    Mishra, N. K., Østergaard, M., Midtgaard, S. R., Strindberg, S. S., Winkler, S., Wu, S., Sørensen, Thomas Just, Hassenkam, Tue, Poulsen, Jens-Christian Navarro, Lo Leggio, Leila, Nielsen, Hanne Mørck, Arleth, Lise, Christensen, Niels Johan, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2021, In: Nanoscale. 13, 18, p. 8467–8473 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Polyamine‐Functionalized 2′‐Amino‐LNA in Oligonucleotides: Facile Synthesis of New Monomers and High‐Affinity Binding towards ssDNA and dsDNA

    Danielsen, M. B., Christensen, Niels Johan, Jørgensen, P. T., Jensen, Knud Jørgen, Wengel, J. & Lou, C., 2021, In: Chemistry: A European Journal. 27, 4, p. 1416-1422 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2020
  11. Published

    Flexibility of the CueR Metal Site Probed by Instantaneous Change of Element and Oxidation State from AgI to CdII

    Balogh, R. K., Gyurcsik, B., Jensen, M., Thulstrup, Peter Waaben, Köster, U., Christensen, Niels Johan, Mørch, F. J., Jensen, Marianne Lund, Jancsó, A. & Hemmingsen, Lars Bo Stegeager, 2020, In: Chemistry: A European Journal. 26, 33, p. 7451-7457 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Formation and structure of fluorescent silver nanoclusters at interfacial binding sites facilitating oligomerization of DNA hairpins

    Geczy, R., Christensen, Niels Johan, Rasmussen, K. K., Kálomista, I., Tiwari, M. K., Shah, P., Yang, S. W., Bjerrum, Morten Jannik & Thulstrup, Peter Waaben, 2020, In: Angewandte Chemie, Int. Ed.. 59, 37, p. 16091-16097 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Self‐Assembly of DNA–Peptide Supermolecules: Coiled‐Coil Peptide Structures Templated by d‐DNA and l-DNA Triplexes Exhibit Chirality‐Independent but Orientation‐Dependent Stabilizing Cooperativity

    Lou, C., Boesen, J. T., Christensen, Niels Johan, Sørensen, K. K., Thulstrup, Peter Waaben, Pedersen, M. N., Giralt, E., Jensen, Knud Jørgen & Wengel, J., 2020, In: Chemistry: A European Journal. 26, 25, p. 5676-5684 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Synthesis and Characterization of Adamantane-Containing Heteropeptides with a Chirality Switch

    Aloisi, A., Christensen, Niels Johan, Sorensen, K. K., Guilbaud-Chereau, C., Jensen, Knud Jørgen & Bianco, A., 2020, In: European Journal of Organic Chemistry. 2020, 7, p. 815-820

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2018
  16. Published

    Glycoconjugate Oxime Formation Catalyzed at Neutral pH: Mechanistic Insights and Applications of 1,4-Diaminobenzene as a Superior Catalyst for Complex Carbohydrates

    Østergaard, M., Christensen, Niels Johan, Hjuler, C. T., Jensen, Knud Jørgen & Thygesen, Mikkel Boas, 2018, In: Bioconjugate Chemistry. 29, 4, p. 1219-1230 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Synergy of Two Highly Specific Biomolecular Recognition Events: Aligning an AT-Hook Peptide in DNA Minor Grooves via Covalent Conjugation to 2′-Amino-LNA

    Ejlersen, M., Christensen, Niels Johan, Sørensen, K. K., Jensen, Knud Jørgen, Wengel, J. & Lou, C., 2018, In: Bioconjugate Chemistry. 29, p. 1025-1029 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2017
  19. Published

    Folding Topology of a Short Coiled-Coil Peptide Structure Templated by an Oligonucleotide Triplex

    Lou, C., Christensen, Niels Johan, Martos Maldonado, M. C., Midtgaard, S. R., Ejlersen, M., Thulstrup, Peter Waaben, Sørensen, K. K., Jensen, Knud Jørgen & Wengel, J., 2017, In: Chemistry - A European Journal. 23, 39, p. 9297-9305 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Oligonucleotides Containing Aminated 2′-Amino-LNA Nucleotides: Synthesis and Strong Binding to Complementary DNA and RNA

    Lou, C., Samuelsen, S. V., Christensen, Niels Johan, Vester, B. & Wengel, J., 2017, In: Bioconjugate Chemistry. 28, 4, p. 1214-1220 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2016
  22. Published

    Construction of insulin 18-mer nanoassemblies driven by coordination to Iron(II) and Zinc(II) ions at distinct sites

    Munch, H. K., Nygård, Jesper, Christensen, Niels Johan, Engelbrekt, C., Østergaard, M., Porsgaard, T., Hoeg-Jensen, T., Zhang, J., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2016, In: Angewandte Chemie International Edition. 55, 7, p. 2378-2381 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  23. Published

    Peptide–oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic

    Lou, C., Martos Maldonado, M. C., Madsen, C. S., Thomsen, R. P., Midtgaard, S. R., Christensen, Niels Johan, Kjems, J., Thulstrup, Peter Waaben, Wengel, J. & Jensen, Knud Jørgen, 2016, In: Nature Communications. 7, 9 p., 12294.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. 2015
  25. Published

    A de novo designed monomeric, compact three helix bundle protein on a carbohydrate template

    Malik, L., Nygård, Jesper, Christensen, Niels Johan, Madsen, C. S., Rösner, Heike Ilona, Kragelund, Birthe Brandt, Høiberg-Nielsen, R., Streicher, W., Arleth, Lise, Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2015, In: ChemBioChem. 16, 13, p. 1905-1918 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Specificity of the metalloregulator CueR for monovalent metal ions: possible functional role of a coordinated thiol?

    Szunyogh, D., Szokolai, H., Thulstrup, Peter Waaben, Larsen, F. H., Gyurcsik, B., Christensen, Niels Johan, Stachura, M. K., Hemmingsen, Lars Bo Stegeager & Jancsó, A., 2015, In: Angewandte Chemie International Edition. 54, 52, p. 15756-15761 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2014
  28. Published

    Methyl effect in azumamides provides insight into histone deacetylase inhibition by macrocycles

    Maolanon, A. R., Villadsen, J. S., Christensen, Niels Johan, Hoeck, C., Friis, T., Harris, P., Gotfredsen, C. H., Fristrup, P. & Olsen, Christian Adam, 2014, In: Journal of Medicinal Chemistry. 57, 22, p. 9644-9657 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2013
  30. Published

    Self-assembly of designed coiled coil peptides studied by small-angle X-ray scattering and analytical ultracentrifugation

    Malik, L., Nygaard, J., Christensen, Niels Johan, Thulstrup, Peter Waaben, Arleth, Lise, Jensen, Knud Jørgen & Streicher, W., 2013, In: Journal of Peptide Science. 19, 5, p. 283-292 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2012
  32. Published

    Metal ion controlled self-assembly of a chemically reengineered protein drug studied by small-angle X-ray scattering

    Nygaard, J., Munch, H. K., Thulstrup, Peter Waaben, Christensen, Niels Johan, Høeg-Jensen, T., Jensen, Knud Jørgen & Arleth, Lise, 2012, In: Langmuir. 28, 33, p. 12159-12170 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2011
  34. Published

    Metal Ion Controlled Polymorphism of a Peptide

    Hemmingsen, Lars Bo Stegeager, Jancso, A., Szunyogh, D., Larsen, F. H., Thulstrup, Peter Waaben, Christensen, Niels Johan & Gyurcsik, B., 15 Jun 2011.

    Research output: Contribution to conferencePosterResearch

  35. Published

    Controlled self-assembly of re-engineered insulin by FeII

    Munch, H. K., Heide, S. T., Christensen, Niels Johan, Høeg-Jensen, T., Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2011, In: Chemistry: A European Journal. 17, 26, p. 7198-7204 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2010
  37. Published

    A combined nuclear magnetic resonance and molecular dynamics study of the two structural motifs for mixed-linkage ß-glucans: methyl ß-cellobioside and methyl ß-laminarabioside

    Christensen, Niels Johan, Hansen, P. I., Larsen, F. H., Folkerman, T., Motawie, Mohammed Saddik & Engelsen, Søren Balling, 2010, In: Carbohydrate Research. 345, 4, p. 474-486 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Computational Studies of the Stability and Chirality of Self-assembled Complexes of a Novel Iron(II)-binding Insulin Derivative

    Christensen, Niels Johan, Munch, H. K., Heide, S. T., Høeg-Jensen, T., Thulstrup, Peter Waaben & Jensen, Knud Jørgen, 2010, In: Journal of Peptide Science. S2

    Research output: Contribution to journalConference abstract in journalResearch

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