Mohammed Saddik Motawie

Mohammed Saddik Motawie

Associate Professor


  1. 2024
  2. E-pub ahead of print

    Disentangling hydroxynitrile glucoside biosynthesis in a barley (Hordeum vulgare) metabolon provides access to elite malting barleys for ethyl carbamate-free whisky production

    Jørgensen, M. E., Houston, K., Jørgensen, Hans Jørgen Lyngs, Thomsen, H. C., Tekaat, L., Krogh, C. T., Mellor, Silas Busck, Braune, K. B., Damm, M. L., Pedas, P. R., Voss, C., Rasmussen, M. W., Nielsen, K., Skadhauge, B., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Dockter, C. & Sørensen, Mette, 23 Apr 2024, (E-pub ahead of print) In: Plant Journal.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    Biosynthesis and biotechnological production of the anti-obesity agent celastrol

    Zhao, Yong, Hansen, N. L., Duan, Yaotao, Prasad, M., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Pateraki, Irini, Stærk, Dan, Bak, Søren, Miettinen, Karel & Kampranis, Sotirios, 2023, In: Nature Chemistry. 15, p. 1236–1246

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Systematic engineering pinpoints a versatile strategy for the expression of functional cytochrome P450 enzymes in Escherichia coli cell factories

    Poborsky, Michal, Crocoll, C., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2023, In: Microbial Cell Factories. 22, 10 p., 219.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The causal mutation leading to sweetness in modern white lupin cultivars

    Mancinotti, Davide, Czepiel, K., Taylor, J. L., Galehshahi, H. G., Møller, L. A., Jensen, M. K., Motawie, Mohammed Saddik, Hufnagel, B., Soriano, A., Yeheyis, L., Kjaerulff, Louise, Péret, B., Stærk, Dan, Wendt, T., Nelson, M. N., Kroc, M. & Geu-Flores, Fernando, 2023, In: Science Advances. 9, 31, 10 p., eadg8866.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2022
  8. Published

    Structure-guided engineering of key amino acids in UGT85B1 controlling substrate and stereo-specificity in aromatic cyanogenic glucoside biosynthesis

    Del Giudice, R., Putkaradze, N., dos Santos, B. M., Hansen, Cecilie Ida Cetti, Crocoll, C., Motawie, Mohammed Saddik, Fredslund, F., Laursen, Tomas & Welner, D. H., 2022, In: Plant Journal. 111, 6, p. 1539-1549

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2021
  10. Published

    An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara

    Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2020
  12. Published

    The dynamics of cyanide defences in the life cycle of an aposematic butterfly: Biosynthesis versus sequestration

    Pinheiro de Castro, É. C., Demirtas, R., Orteu, A., Olsen, C. E., Motawie, Mohammed Saddik, Zikan Cardoso, M., Zagrobelny, Mika & Bak, Søren, Jan 2020, In: Insect Biochemistry and Molecular Biology. 116, p. 1-9 103259.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A flavin-dependent monooxygenase catalyzes the initial step in cyanogenic glycoside synthesis in ferns

    Thodberg, S., Sørensen, Mette, Bellucci, M., Crocoll, C., Bendtsen, Amalie Kofoed, Nelson, D. R., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Neilson, Elizabeth Heather Jakobsen, 2020, In: Communications Biology . 3, 11 p., 507.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    Golgi-localized exo-β1,3-galactosidases involved in AGP modification and root cell expansion in Arabidopsis

    Nibbering, P., Petersen, Bent L, Motawie, Mohammed Saddik, Jørgensen, Bodil, Ulvskov, Peter & Niittylä, T., 2020, In: Journal of Biological Chemistry. 295, 31, p. 10851-10592

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Golgi-localized exo-β1,3-galactosidases involved in cell expansion and root rowth in Arabidopsis

    Nibbering, P., Petersen, Bent L, Motawie, Mohammed Saddik, Jørgensen, Bodil, Ulvskov, Peter & Niittylä, T., 2020, In: Journal of Biological Chemistry. 295, 31, p. 10581-10592

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Phenolic cross-links: building and de-constructing the plant cell wall

    Mnich, E., Bjarnholt, Nanna, Eudes, A., Harholt, J., Holland, C., Jørgensen, Bodil, Larsen, F. H., Liu, M., Manat, R., Meyer, A. S., Mikkelsen, J. D., Motawie, Mohammed Saddik, Muschiol, J., Møller, Birger Lindberg, Møller, S. R., Perzon, A., Petersen, Bent L, Ravn, J. L. & Ulvskov, Peter, 2020, In: Natural Product Reports. 37, 7, p. 919-961 43 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Stabilization of dhurrin biosynthetic enzymes from Sorghum bicolor using a natural deep eutectic solvent

    Knudsen, C., Bavishi, K., Viborg, K. M., Drew, D. P., Simonsen, H. T., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Laursen, Tomas, 2020, In: Phytochemistry. 170, 9 p., 112214.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Synthetic Biology of Cannabinoids and Cannabinoid Glucosides in Nicotiana benthamiana and Saccharomyces cerevisiae

    Gülck, T., Booth, J. K., Carvalho, Â., Khakimov, Bekzod, Crocoll, C., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Bohlmann, J. & Gallage, N. J., 2020, In: Journal of Natural Products. 83, 10, p. 2877-2893 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2019
  21. Published

    An Optimized Screen Reduces the Number of GA Transporters and Provides Insights Into Nitrate Transporter 1/Peptide Transporter Family Substrate Determinants

    Wulff, N., Ernst, H. A., Jørgensen, M. E., Lambertz, S., Maierhofer, T., Belew, Zeinu Mussa, Crocoll, C., Motawie, Mohammed Saddik, Geiger, D., Jørgensen, Flemming Steen, Mirza, Osman Asghar & Nour-Eldin, Hussam Hassan, 3 Oct 2019, In: Frontiers in Plant Science. 10, 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Defining optimal electron transfer partners for light-driven cytochrome P450 reactions

    Mellor, Silas Busck, Vinde, M. H., Nielsen, A. Z., Hanke, G. T., Abdiaziz, K., Roessler, M. M., Burow, Meike, Motawie, Mohammed Saddik, Møller, Birger Lindberg & Jensen, Poul Erik, 1 Sep 2019, In: Metabolic Engineering. 55, p. 33-43

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Deletion of biosynthetic genes, specific SNP patterns and differences in transcript accumulation cause variation in hydroxynitrile glucoside content in barley cultivars

    Ehlert, M., Jagd, L. M., Braumann, I., Dockter, C., Crocoll, C., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Lyngkjær, M. F., 5 Apr 2019, In: Scientific Reports. 9, p. 1-10 5730.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Sequestration and functional diversification of cyanogenic glucosides in the life cycle of Heliconius melpomene

    Castro, É. C. P. D., Demirtas, R., Orteu, A., Olsen, C. E., Motawie, Mohammed Saddik, Cardoso, M. Z., Zagrobelny, Mika & Bak, Søren, 2019, bioRxiv, 31 p.

    Research output: Working paperPreprintResearch

  25. 2018
  26. Published

    Glutathione transferases catalyze recycling of auto-toxic cyanogenic glucosides in sorghum

    Bjarnholt, Nanna, Neilson, Elizabeth Heather Jakobsen, Crocoll, C., Jørgensen, Kirsten, Motawie, Mohammed Saddik, Olsen, C. E., Dixon, D. P., Edwards, R. & Møller, Birger Lindberg, 2018, In: Plant Journal. 94, 6, p. 1109-1125

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Synthesis of 11-carbon terpenoids in yeast using protein and metabolic engineering

    Ignea, C., Pontini, M., Motawie, Mohammed Saddik, Maffei, M. E., Makris, A. M. & Kampranis, Sotirios, 2018, In: Nature Chemical Biology. 14, 12, p. 1090-1098 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Vitamin D-5 in Arabidopsis thaliana

    Silvestro, D., Villette, C., Delecolle, J., Olsen, C. E., Motawie, Mohammed Saddik, Geoffroy, P., Miesch, M., Jensen, Poul Erik, Heintz, D. & Schaller, H., 2018, In: Scientific Reports. 8, p. 1-8 16348.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2017
  30. Published

    Bottom-up elucidation of glycosidic bond stereochemistry

    Gray, C. J., Schindler, B., Migas, L. G., Picmanova, M., Allouche, A. R., Green, A. P., Mandal, S., Motawie, Mohammed Saddik, Sánchez Pérez, R., Bjarnholt, Nanna, Møller, Birger Lindberg, Rijs, A. M., Barran, P. E., Compagnon, I., Eyers, C. E. & Flitsch, S. L., 2017, In: Analytical Chemistry. 89, 8, p. 4540-4549 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Chemical Synthesis of L-Fucose Derivatives for Acceptor Specificity Characterisation of Plant Cell Wall Glycosyltransferases

    Damager, I., Olsen, C. E., Madsen, J. E., Jørgensen, Bodil, Petersen, Bent L, Ulvskov, Peter, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2017, In: ChemistrySelect. 2, 3, p. 997-1007 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Degradation of lignin β-aryl ether units in Arabidopsis thaliana expressing LigD, LigF and LigG from Sphingomonas paucimobilis SYK-6

    Mnich, E., Vanholme, R., Oyarce, P., Liu, S., Lu, F., Goeminne, G., Jørgensen, Bodil, Motawie, Mohammed Saddik, Boerjan, W., Ralph, J., Ulvskov, Peter, Møller, Birger Lindberg, Bjarnholt, Nanna & Harholt, J., 2017, In: Plant Biotechnology Journal. 15, 5, p. 581-593 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Development of novel monoclonal antibodies against starch and ulvan - implications for antibody production against polysaccharides with limited immunogenicity

    Rydahl, M. G., Kracun, S. K., Fangel, J. U., Michel, G., Guillouzo, A., Génicot, S., Mravec, Jozef, Harholt, J., Wilkens, C., Motawie, Mohammed Saddik, Svensson, B., Tranquet, O., Ralet, M., Jørgensen, Bodil, Domozych, D. S. & Willats, W. G. T., 2017, In: Scientific Reports. 7, 1, 13 p., 9326.

    Research output: Contribution to journalJournal articleResearchpeer-review

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