Michael Jonathan Davies

Michael Jonathan Davies

Professor


  1. 2022
  2. Published

    Oxidative Crosslinking of Peptides and Proteins: Mechanisms of Formation, Detection, Characterization and Quantification

    Fuentes Lemus, Eduardo, Hägglund, Per Mårten, López-Alarcón, C. & Davies, Michael Jonathan, 1 Jan 2022, In: Molecules. 27, 1, p. 1-31 15.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Oxidant-mediated modification and cross-linking of beta-2-microglobulin

    Jiang, S., Fuentes Lemus, Eduardo & Davies, Michael Jonathan, 2022, In: Free Radical Biology and Medicine. 187, p. 59-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published
  5. Published

    Synthesis and cellular evaluation of click-chemistry probes to study the biological effects of alpha, beta-unsaturated carbonyls

    Morozzi, C., Sauerland, M., Gamon, Luke Francis, Manandhar, Asmita, Ulven, Trond & Davies, Michael Jonathan, 2022, In: Redox Biology. 52, 8 p., 102299.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Reaction of cysteine residues with oxidized tyrosine residues mediates cross-linking of photo-oxidized casein proteins

    Rossi, C., Fuentes Lemus, Eduardo & Davies, Michael Jonathan, 2022, In: Food Chemistry. 385, 7 p., 132667.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Accepted/In press

    Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology

    Sies, H., Belousov, V. V., Chandel, N. S., Davies, Michael Jonathan, Jones, D. P., Mann, G. E., Murphy, M. P., Yamamoto, M. & Winterbourn, C., 2022, (Accepted/In press) In: Nature Reviews Molecular Cell Biology. p. 1-17

    Research output: Contribution to journalReviewResearchpeer-review

  8. 2021
  9. Published

    The Use of Membrane Filtration to Increase Native Whey Proteins in Infant Formula

    Chen, Y., Callanan, M., Shanahan, C., Tobin, J., Gamon, Luke Francis, Davies, Michael Jonathan, Giblin, L. & Brodkorb, A., Sep 2021, In: Dairy. 2, 4, p. 515-529

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Anthocyanin complex niosome gel accelerates oral wound healing: In vitro and clinical studies

    Damrongrungruang, T., Paphangkorakit, J., Limsitthichaikoon, S., Khampaenjiraroch, B., Davies, Michael Jonathan, Sungthong, B. & Priprem, A., 2021, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 37, 14 p., 102423.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    "What, where and how much? Key challenges in protein oxidation"

    Davies, Michael Jonathan, 2021, In: Free Radical Biology and Medicine. 165, Suppl. 1, p. 15-15 Suppl. 13-1.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  12. Published

    Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases

    Davies, Michael Jonathan, 2021, In: Pharmacology and Therapeutics. 218, 23 p., 107685.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues

    Flouda, K., Gammelgaard, Bente, Davies, Michael Jonathan & Hawkins, Clare Louise, May 2021, In: Redox Biology. 41, 101873.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Role of myeloperoxidase-derived oxidants in the induction of vascular smooth muscle cell damage

    Flouda, K., Mercer, J., Davies, Michael Jonathan & Hawkins, Clare Louise, 2021, In: Free Radical Biology & Medicine. 166, p. 165-177

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Effect of macromolecular crowding on protein oxidation: Consequences on the rate, extent and oxidation pathways

    Fuentes Lemus, Eduardo, Reyes, J. S., Gamon, Luke Francis, López-Alarcón, C. & Davies, Michael Jonathan, 2021, In: Redox Biology. 48, 15 p., 102202.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    High concentrations of casein proteins exacerbate radical chain reactions and increase the extent of oxidative damage

    Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael Jonathan, 2021, In: Food Hydrocolloids. 121, 16 p., 107060.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Oxidation of lysozyme induced by peroxyl radicals involves amino acid modifications, loss of activity, and formation of specific crosslinks

    Fuentes Lemus, Eduardo, Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2021, In: Free Radical Biology and Medicine. 167, p. 258-270

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia-reperfusion injury in rats

    Hall, L., Guo, C., Tandy, S., Broadhouse, K., Dona, A. C., Malle, E., Bartels, Emil Daniel, Christoffersen, Christina, Grieve, S. M., Figtree, G., Hawkins, Clare Louise & Davies, Michael Jonathan, 2021, In: Scientific Reports. 11, 1, 18 p., 12712.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage

    Hawkins, Clare Louise & Davies, Michael Jonathan, 2021, In: Free Radical Biology and Medicine. 172, p. 633-651

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Crosslinking of human plasma C-reactive protein to human serum albumin via disulfide bond oxidation

    Jiang, S., Hägglund, Per Mårten, Carroll, L., Rasmussen, L. M. & Davies, Michael Jonathan, 2021, In: Redox Biology. 41, 17 p., 101925.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Formation of protein cross-links by singlet oxygen-mediated disulfide oxidation

    Jiang, S., Carroll, L., Mariotti, M., Hägglund, Per Mårten & Davies, Michael Jonathan, 2021, In: Redox Biology. 41, 16 p., 101874.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Oxidation of protein disulfide bonds by singlet oxygen gives rise to glutathionylated proteins

    Jiang, S., Carroll, L., Rasmussen, L. M. & Davies, Michael Jonathan, 2021, In: Redox Biology. 38, 16 p., 101822.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Phenotypic changes to vascular smooth muscle cells induced by extracellular matrix modification

    Jørgensen, Sara Marthedal, Chuang, Christine & Davies, Michael Jonathan, 2021, In: Free Radical Biology & Medicine. 165, Suppl. 1, p. 36-37 NC38.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  24. Published

    Phenotypic changes to vascular smooth muscle cells induced by oxidant-modified extracellular matrix

    Jørgensen, Sara Marthedal, Chuang, Christine & Davies, Michael Jonathan, 2021, In: Free Radical Biology and Medicine. 165, 1 p., NC38.

    Research output: Contribution to journalConference abstract in journalResearch

  25. Published

    Cross-linking and modification of fibronectin by peroxynitrous acid: Mapping and quantification of damage provides a new model for domain interactions

    Mariotti, M., Rogowska-Wrzesinska, A., Hägglund, Per Mårten & Davies, Michael Jonathan, 2021, In: Journal of Biological Chemistry. 296, 100360.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Enzymatic cross-linking of collagens in organ fibrosis - resolution and assessment

    Pehrsson, M., Mortensen, J. H., Manon-Jensen, T., Bay-Jensen, A., Karsdal, M. A. & Davies, Michael Jonathan, 2021, In: Expert Review of Molecular Diagnostics. 21, 10, p. 1049-1064

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    M. jannaschii FtsZ, a key protein in bacterial cell division, is inactivated by peroxyl radical-mediated methionine oxidation

    Reyes, J. S., Fuentes Lemus, Eduardo, Aspée, A., Davies, Michael Jonathan, Monasterio, O. & López-Alarcón, C., 2021, In: Free Radical Biology and Medicine. 166, p. 53-66

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Kinetic assessment of Michael addition reactions of alpha, beta-unsaturated carbonyl compounds to amino acid and protein thiols

    Sauerland, M., Mertes, R., Morozzi, C., Eggler, A. L., Gamon, Luke Francis & Davies, Michael Jonathan, 2021, In: Free Radical Biology and Medicine. 169, p. 1-11 569.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Processed foods drive intestinal barrier permeability and microvascular diseases

    Snelson, M., Tan, S. M., Clarke, R. E., De Pasquale, C., Thallas-Bonke, V., Nguyen, T. V., Penfold, S. A., Harcourt, B. E., Sourris, K. C., Lindblom, R. S., Ziemann, M., Steer, D., El-Osta, A., Davies, Michael Jonathan, Donnellan, L., Deo, P., Kellow, N. J., Cooper, M. E., Woodruff, T. M., Mackay, C. R., Forbes, J. M. & Coughlan, M. T., 2021, In: Science Advances. 7, 14, eabe4841.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Suppressive effect of 1,4-anhydro-4-seleno-D-talitol (SeTal) on atopic dermatitis-like skin lesions in mice through regulation of inflammatory mediators

    Voss, G. T., de Oliveira, R. L., Davies, Michael Jonathan, Domingues, W. B., Campos, V. F., Soares, M. P., Luchese, C., Schiesser, C. H. & Wilhelm, E. A., 2021, In: Journal of Trace Elements in Medicine and Biology. 67, 10 p., 126795.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Dynein regulates Kv7.4 channel trafficking from the cell membrane

    van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael Jonathan, Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. 2020
  33. Published

    Photobiocatalysis by a Lytic Polysaccharide Monooxygenase Using Intermittent Illumination

    Blossom, B. M., Russo, D. A., Singh, R. K., Van Oort, B., Keller, M. B., Simonsen, Tor Ivan, Perzon, A., Gamon, Luke Francis, Davies, Michael Jonathan, Cannella, D., Croce, R., Jensen, Poul Erik, Bjerrum, Morten Jannik & Felby, C., 2020, In: ACS Sustainable Chemistry & Engineering. 8, 25, p. 9301-9310 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification

    Cai, H., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael Jonathan, 2020, In: Scientific Reports. 13 p., 666.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Interaction kinetics of selenium -containing compounds with oxidants

    Carroll, L., Gardiner, K., Ignasiak, M., Holmehave, J., Shimodaira, S., Breitenbach, T., Iwaoka, M., Ogilby, P. R., Pattison, David & Davies, Michael Jonathan, 2020, In: Free Radical Biology and Medicine. 155, p. 58-68

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Oxidant-induced glutathionylation at protein disulfide bonds

    Carroll, L., Jiang, S., Irnstorfer, J., Beneyto, S., Ignasiak, M. T., Rasmussen, L. M., Rogowska-Wrzesinska, A. & Davies, Michael Jonathan, 20 Nov 2020, In: Free Radical Biology and Medicine. 160, p. 513-525 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease

    Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In: Antioxidants & Redox Signaling. 32, 13, p. 957-981

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion

    Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael Jonathan & López-Alarcón, C., 2020, In: RSC Advances. 10, 43, p. 25786-25800 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Photo -oxidation of lysozyme triggered by riboflavin is O 2-dependent, occurs via mixed type 1 and type 2 pathways, and results in inactivation, site-specific damage and intra- and inter -molecular crosslinks

    Fuentes-Lemus, E., Mariotti, M., Reyes, J., Leinisch, F., Hägglund, Per Mårten, Silva, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2020, In: Free Radical Biology and Medicine. 152, p. 61-73

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Absolute quantitative analysis of intact and oxidized amino acids by LC-MS without prior derivatization

    Gamon, Luke Francis, Guo, C., He, Jianfei, Hägglund, Per Mårten, Hawkins, Clare Louise & Davies, Michael Jonathan, Sep 2020, In: Redox Biology. 36, 9 p., 101586.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Iodide modulates protein damage induced by the inflammation-associated heme enzyme myeloperoxidase

    Gamon, Luke Francis, Dieterich, S., Ignasiak, M. T., Schrameyer, V. & Davies, Michael Jonathan, 2020, In: Redox Biology. 28, 12 p., 101331.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Endothelial nitric oxide synthase plays a protective role in endothelial cells and cardiomyocytes against myocardial infarction

    Gentile, C., Kesteven, S., Wu, J., Davies, Michael Jonathan, Bursill, C., Feneley, M. & Figtree, G., 2020, In: Journal of Molecular and Cellular Cardiology. 140, p. 31-31

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  43. Published

    Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages

    Guo, C., Sileikaite, Inga, Davies, Michael Jonathan & Hawkins, Clare Louise, 2020, In: Antioxidants. 9, 12, 14 p., 1255.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages

    Guo, C., Davies, Michael Jonathan & Hawkins, Clare Louise, Sep 2020, In: Redox Biology. 36, 14 p., 101666.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin

    He, Jianfei, Becares, E. R., Thulstrup, Peter Waaben, Gamon, Luke Francis, Pedersen, J. N., Otzen, D., Gourdon, Pontus Emanuel, Davies, Michael Jonathan & Hägglund, Per Mårten, 2020, In: Redox Biology. 36, 11 p., 101631.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Unexpected light emission from tyrosyl radicals as a probe for tyrosine oxidation

    Ignasiak, M., Frackowiak, K., Pedzinski, T., Davies, Michael Jonathan & Marciniak, B., 2020, In: Free Radical Biology and Medicine. 153, p. 12-16 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Dermal fibroblasts have different extracellular matrix profiles induced by TGF-beta, PDGF and IL-6 in a model for skin fibrosis

    Juhl, P., Bondesen, S., Hawkins, Clare Louise, Karsdal, M. A., Bay-Jensen, A., Davies, Michael Jonathan & Siebuhr, A. S., 2020, In: Scientific Reports. 10, 1, 10 p., 17300.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Characterization of disulfide (cystine) oxidation by HOCl in a model peptide: Evidence for oxygen addition, disulfide bond cleavage and adduct formation with thiols

    Karimi, M., Crossett, B., Cordwell, S. J., Pattison, David & Davies, Michael Jonathan, 2020, In: Free Radical Biology and Medicine. 154, p. 62-74 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    UV oxidation of cyclic AMP receptor protein, a global bacterial gene regulator, decreases DNA binding and cleaves DNA at specific sites

    Leinisch, F., Mariotti, M., Andersen, S. H., Lindemose, S., Hägglund, Per Mårten, Møllegaard, Niels Erik & Davies, Michael Jonathan, 2020, In: Scientific Reports. 10, 1, 11 p., 3106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Azocompounds as generators of defined radical species: Contributions and challenges for free radical research

    López-Alarcón, C., Fuentes-Lemus, E., Figueroa, J. D., Dorta, E., Schöneich, C. & Davies, Michael Jonathan, 2020, In: Free Radical Biology and Medicine. 160, p. 78-91

    Research output: Contribution to journalReviewResearchpeer-review

  51. Published

    The leucine-rich repeat domain of human peroxidasin 1 promotes binding to laminin in basement membranes

    Sevcnikar, B., Schaffner, I., Chuang, Christine, Gamon, Luke Francis, Paumann-Page, M., Hofbauer, S., Davies, Michael Jonathan, Furtmüller, P. G. & Obinger, C., 15 Aug 2020, In: Archives of Biochemistry and Biophysics. 689, 7 p., 108443.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Inhibition and crosslinking of the selenoprotein thioredoxin reductase-1 by p-benzoquinone

    Shu, N., Cheng, Q., Arner, E. S. J. & Davies, Michael Jonathan, 2020, In: Redox Biology. 28, 9 p., 101335 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Modification of Cys residues in human thioredoxin-1 by p-benzoquinone causes inhibition of its catalytic activity and activation of the ASK1/p38-MAPK signalling pathway

    Shu, N., Hägglund, Per Mårten, Cai, H., Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2020, In: Redox Biology. 29, UNSP 101400.

    Research output: Contribution to journalJournal articleResearchpeer-review

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