Matthias Mann

Matthias Mann

Professor, head of research, Professor

Member of:

    ORCID: 0000-0003-1292-4799

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    1 - 41 out of 41Page size: 100
    1. 2021

    2. Proteomic Analysis Identifies NDUFS1 and ATP5O as Novel Markers for Survival Outcome in Prostate Cancer

      Wiebringhaus, R., Pecoraro, M., Neubauer, H. A., Trachtová, K., Trimmel, B., Wieselberg, M., Pencik, J., Egger, G., Krall, C., Moriggl, R., Mann, Matthias, Hantusch, B. & Kenner, L., 30 Nov 2021, In: Cancers. 13, 23

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Signaling defects associated with insulin resistance in nondiabetic and diabetic individuals and modification by sex

      Haider, N., Lebastchi, J., Jayavelu, A. K., Batista, T. M., Pan, H., Dreyfuss, J. M., Carcamo-Orive, I., Knowles, J. W., Mann, Matthias & Kahn, C. R., 1 Nov 2021, In: The Journal of Clinical Investigation. 131, 21

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling

      Tanzer, M. C., Bludau, I., Stafford, C. A., Hornung, V. & Mann, Matthias, 18 Oct 2021, In: Nature Communications. 12, 1, p. 6053

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation

      Hoefig, K. P., Reim, A., Gallus, C., Wong, E. H., Behrens, G., Conrad, C., Xu, M., Kifinger, L., Ito-Kureha, T., Defourny, K. A. Y., Geerlof, A., Mautner, J., Hauck, S. M., Baumjohann, D., Feederle, R., Mann, Matthias, Wierer, M., Glasmacher, E. & Heissmeyer, V., 1 Sep 2021, In: Nature Communications. 12, 1, p. 5208

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Artificial intelligence for proteomics and biomarker discovery

      Mann, Matthias, Kumar, C., Zeng, W. & Strauss, M. T., 18 Aug 2021, In: Cell Systems. 12, 8, p. 759-770 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    7. Trapped Ion Mobility Spectrometry (TIMS) and Parallel Accumulation - Serial Fragmentation (PASEF) in Proteomics

      Meier, F., Park, M. A. & Mann, Matthias, 17 Aug 2021, (E-pub ahead of print) In: Molecular and Cellular Proteomics. p. 100138

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Identification of the transcription factor MAZ as a regulator of erythropoiesis

      Deen, D., Butter, F., Daniels, D. E., Ferrer-Vicens, I., Ferguson, D. C. J., Holland, M. L., Samara, V., Sloane-Stanley, J. A., Ayyub, H., Mann, Matthias, Frayne, J., Garrick, D. & Vernimmen, D., 10 Aug 2021, In: Blood advances. 5, 15, p. 3002-3015 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Identification of covalent modifications regulating immune signaling complex composition and phenotype

      Frauenstein, A., Ebner, S., Hansen, F. M., Sinha, A., Phulphagar, K., Swatek, K., Hornburg, D., Mann, Matthias & Meissner, F., Jul 2021, In: Molecular Systems Biology. 17, 7, p. e10125

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes

      Wigger, L., Barovic, M., Brunner, A-D., Marzetta, F., Schöniger, E., Mehl, F., Kipke, N., Friedland, D., Burdet, F., Kessler, C., Lesche, M., Thorens, B., Bonifacio, E., Legido-Quigley, C., Barbier Saint Hilaire, P., Delerive, P., Dahl, A., Klose, C., Gerl, M. J., Simons, K. & 7 others, Aust, D., Weitz, J., Distler, M., Schulte, A. M., Mann, Matthias, Ibberson, M. & Solimena, M., 28 Jun 2021, (E-pub ahead of print) In: Nature Metabolism.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme

      Sherpa, D., Chrustowicz, J., Qiao, S., Langlois, C. R., Hehl, L. A., Gottemukkala, K. V., Hansen, F. M., Karayel, O., von Gronau, S., Prabu, J. R., Mann, Matthias, Alpi, A. F. & Schulman, B. A., 22 Apr 2021, (E-pub ahead of print) In: Molecular Cell.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila

      Tain, L. S., Sehlke, R., Meilenbrock, R. L., Leech, T., Paulitz, J., Chokkalingam, M., Nagaraj, N., Grönke, S., Fröhlich, J., Atanassov, I., Mann, Matthias, Beyer, A. & Partridge, L., 21 Apr 2021, In: eLife. 10

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV

      Stukalov, A., Girault, V., Grass, V., Karayel, O., Bergant, V., Urban, C., Haas, D. A., Huang, Y., Oubraham, L., Wang, A., Hamad, M. S., Piras, A., Hansen, F. M., Tanzer, M. C., Paron, I., Zinzula, L., Engleitner, T., Reinecke, M., Lavacca, T. M., Ehmann, R. & 10 others, Wölfel, R., Jores, J., Kuster, B., Protzer, U., Rad, R., Ziebuhr, J., Thiel, V., Scaturro, P., Mann, Matthias & Pichlmair, A., 12 Apr 2021, (E-pub ahead of print) In: Nature.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. A proteomic atlas of the neointima identifies novel druggable targets for preventive therapy

      Wierer, M., Werner, J., Wobst, J., Kastrati, A., Cepele, G., Aherrahrou, R., Sager, H. B., Erdmann, J., Dichgans, M., Flockerzi, V., Civelek, M., Dietrich, A., Mann, Matthias, Schunkert, H. & Kessler, T., 8 Apr 2021, (E-pub ahead of print) In: European Heart Journal.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-β pathway

      Takahashi, M., Lio, C. J., Campeau, A., Steger, M., Ay, F., Mann, Matthias, Gonzalez, D. J., Jain, M. & Sharma, S., Apr 2021, In: Nature Immunology. 22, 4, p. 485-496 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

      Liwocha, J., Krist, D. T., van der Heden van Noort, G. J., Hansen, F. M., Truong, V. H., Karayel, O., Purser, N., Houston, D., Burton, N., Bostock, M. J., Sattler, M., Mann, Matthias, Harrison, J. S., Kleiger, G., Ovaa, H. & Schulman, B. A., Mar 2021, In: Nature Chemical Biology. 17, 3, p. 272-279 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.Z Acetylation at Regulatory Regions

      Procida, T., Friedrich, T., Jack, A. P. M., Peritore, M., Bönisch, C., Eberl, H. C., Daus, N., Kletenkov, K., Nist, A., Stiewe, T., Borggrefe, T., Mann, Matthias, Bartkuhn, M. & Hake, S. B., 12 Jan 2021, In: International Journal of Molecular Sciences. 22, 2

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology

      Hansen, F. M., Tanzer, M. C., Brüning, F., Bludau, I., Stafford, C., Schulman, B. A., Robles, M. S., Karayel, O. & Mann, Matthias, 11 Jan 2021, In: Nature Communications. 12, 1, p. 254

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. The Hippo pathway controls myofibril assembly and muscle fiber growth by regulating sarcomeric gene expression

      Kaya-Çopur, A., Marchiano, F., Hein, M. Y., Alpern, D., Russeil, J., Luis, N. M., Mann, Matthias, Deplancke, B., Habermann, B. H. & Schnorrer, F., 6 Jan 2021, In: eLife. 10

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      A new parallel high-pressure packing system enables rapid multiplexed production of capillary columns

      Müller-Reif, J. B., Hansen, F. M., Schweizer, L., Treit, P. V., Geyer, P. E. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 10 p., 100082.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. AlphaTims: Indexing Trapped Ion Mobility Spectrometry-TOF Data for Fast and Easy Accession and Visualization

      Willems, S., Voytik, E., Skowronek, P., Strauss, Maximilian & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, p. 100149

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Cohort profile: the MUNICH Preterm and Term Clinical study (MUNICH-PreTCl), a neonatal birth cohort with focus on prenatal and postnatal determinants of infant and childhood morbidity

      Pangratz-Fuehrer, S., Genzel-Boroviczény, O., Bodensohn, W. E., Eisenburger, R., Scharpenack, J., Geyer, P. E., Müller-Reif, J. B., van Hagen, N., Müller, A. M., Jensen, Majken Karoline, Klein, C., Mann, Matthias & Nussbaum, C., 2021, In: BMJ Open. 11, 6, 13 p., e050652.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Deep learning the collisional cross sections of the peptide universe from a million experimental values

      Meier, F., Köhler, N. D., Brunner, A. D., Wanka, J. M. H., Voytik, E., Strauss, M. T., Theis, F. J. & Mann, Matthias, 2021, In: Nature Communications. 12, 12 p., 1185.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

      Deshmukh, Atul Shahaji, Steenberg, D. E., Hostrup, Morten, Birk, Jesper Bratz, Larsen, Jeppe Kjærgaard, Santos, A., Kjøbsted, Rasmus, Hingst, J. R., Schéele, Camilla Charlotte Nielsen, Murgia, M., Kiens, Bente, Richter, Erik A., Mann, Matthias & Wojtaszewski, Jørgen F P, 2021, In: Nature Communications. 12, 15 p., 304.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Defining NASH from a multi-omics systems biology perspective

      Niu, Lili, Sulek, K., Vasilopoulou, C. G., Santos, A., Albrechtsen, Nicolai Jacob Wewer, Rasmussen, Simon, Meier, F. & Mann, Matthias, 2021, In: Journal of Clinical Medicine. 10, 20, 22 p., 4673.

      Research output: Contribution to journal › Review › Research › peer-review

    26. Published

      Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains

      Nagao, H., Cai, W., Albrechtsen, Nicolai Jacob Wewer, Steger, M., Batista, T. M., Pan, H., Dreyfuss, J. M., Mann, Matthias & Kahn, C. R., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 17, e2019474118.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Ethical Principles, Constraints and Opportunities in Clinical Proteomics

      Porsdam Mann, Sebastian, Treit, P. V., Geyer, P. E., Omenn, G. S. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 14 p., 100046.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes

      Dall, M., Hassing, Anna Skab, Niu, Lili, Nielsen, Thomas Svava, Ingerslev, L. R., Sulek, K., Trammell, Sam, Gillum, M. P., Barrès, Romain, Larsen, Steen, Poulsen, Steen Seier, Mann, Matthias, Ørskov, Cathrine & Treebak, Jonas Thue, 2021, In: Journal of Biological Chemistry. 297, 6, 26 p., 101388.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      High-resolution serum proteome trajectories in COVID-19 reveal patient-specific seroconversion

      Geyer, P. E., Arend, F. M., Doll, S., Louiset, M., Virreira Winter, S., Müller-Reif, J. B., Torun, F. M., Weigand, M., Eichhorn, P., Bruegel, M., Strauss, M. T., Holdt, L. M., Mann, Matthias & Teupser, D., 2021, In: EMBO Molecular Medicine. 13, 8, 16 p., e14167.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

      Andersen, Jens Velde, Skotte, Niels Henning, Christensen, S. K., Polli, F. S., Shabani, M., Markussen, K. H., Haukedal, H., Westi, Emil Winther, Diaz-delCastillo, M., Sun, R. C., Kohlmeier, Kristi Anne, Schousboe, Arne, Gentry, M. S., Tanila, H., Freude, Kristine, Aldana, Blanca, Mann, Matthias & Waagepetersen, Helle S., 2021, In: Cell Death & Disease. 12, 11, 13 p., 954 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Homology-directed repair protects the replicating genome from metabolic assaults

      Somyajit, K., Spies, J., Coscia, F., Kirik, U., Rask, M., Lee, J., Neelsen, K. J., Mund, Andreas, Jensen, Lars Juhl, Paull, T. T., Mann, Matthias & Lukas, Jiri, 2021, In: Developmental Cell. 56, 4, p. 461-477.e7

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers

      Mayr, C. H., Simon, L. M., Leuschner, G., Ansari, M., Schniering, J., Geyer, P. E., Angelidis, I., Strunz, M., Singh, P., Kneidinger, N., Reichenberger, F., Silbernagel, E., Böhm, S., Adler, H., Lindner, M., Maurer, B., Hilgendorff, A., Prasse, A., Behr, J., Mann, M. & 3 others, Eickelberg, O., Theis, F. J. & Schiller, H. B., 2021, In: EMBO Molecular Medicine. e12871.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Interaction of 7SK with the Smn complex modulates snRNP production

      Ji, C., Bader, J., Ramanathan, P., Hennlein, L., Meissner, F., Jablonka, S., Mann, Matthias, Fischer, U., Sendtner, M. & Briese, M., 2021, In: Nature Communications. 12, 1, 15 p., 1278.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

      Kruse, T., Benz, C., Garvanska, D. H., Lindqvist, R., Mihalic, F., Coscia, F., Inturi, R., Sayadi, A., Simonetti, L., Nilsson, E., Ali, M., Kliche, J., Moliner Morro, A., Mund, A., Andersson, E., McInerney, G., Mann, M., Jemth, P., Davey, N. E., Överby, A. K. & 2 others, Nilsson, Jakob & Ivarsson, Y., 2021, In: Nature Communications. 12, 1, 13 p., 6761.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin

      Ghanawi, H., Hennlein, L., Zare, A., Bader, J., Salehi, S., Hornburg, D., Ji, C., Sivadasan, R., Drepper, C., Meissner, F., Mann, Matthias, Jablonka, S., Briese, M. & Sendtner, M., 2021, In: Nucleic Acids Symposium Series. 49, 21, p. 12284-12305 22 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Molecular Origin of Blood-based Infrared Spectroscopic Fingerprints

      Voronina, L., Leonardo, C., Mueller-Reif, J. B., Geyer, P. E., Huber, M., Trubetskov, M., Kepesidis, K. V., Behr, J., Mann, Matthias, Krausz, F. & Žigman, M., 2021, In: Angewandte Chemie International Edition. 60, 31, p. 17060-17069

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Molecular response to PARP1 inhibition in ovarian cancer cells as determined by mass spectrometry based proteomics

      Franz, A., Coscia, F., Shen, C., Charaoui, L., Mann, Matthias & Sander, C., 2021, In: Journal of Ovarian Research. 14, 14 p., 140.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Plasma proteomic data can contain personally identifiable, sensitive information and incidental findings

      Geyer, P. E., Porsdam Mann, Sebastian, Treit, P. V. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Protein profile of fiber types in human skeletal muscle: a single-fiber proteomics study

      Murgia, M., Nogara, L., Baraldo, M., Reggiani, C., Mann, Matthias & Schiaffino, S., 2021, In: Skeletal Muscle. 11, 1, 19 p., 24.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Reply to "Quality control requirements for the correct annotation of lipidomics data"

      Vasilopoulou, C. G., Sulek, K., Brunner, A., Meitei, N. S., Schweiger-Hufnagel, U., Meyer, S. W., Barsch, A., Mann, Matthias & Meier, F., 2021, In: Nature Communications. 12, 4 p., 4772.

      Research output: Contribution to journal › Journal article › Research

    41. Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription Factor F) Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism

      von Scheidt, M., Zhao, Y., de Aguiar Vallim, T. Q., Che, N., Wierer, M., Seldin, M. M., Franzén, O., Kurt, Z., Pang, S., Bongiovanni, D., Yamamoto, M., Edwards, P. A., Ruusalepp, A., Kovacic, J. C., Mann, Matthias, Björkegren, J. L. M., Lusis, A. J., Yang, X. & Schunkert, H., 2021, In: Circulation. 143, 18, p. 1809-1823

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Urinary proteome profiling for stratifying patients with familial Parkinson’s disease

      Virreira Winter, S., Karayel, O., Strauss, M. T., Padmanabhan, S., Surface, M., Merchant, K., Alcalay, R. N. & Mann, Matthias, 2021, In: EMBO Molecular Medicine. 13, 3, 19 p., e13257.

      Research output: Contribution to journal › Journal article › Research › peer-review

    ID: 5650809