Matthias Mann

Matthias Mann

Professor, head of research, Professor

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    ORCID: 0000-0003-1292-4799

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    1. Published

      A new parallel high-pressure packing system enables rapid multiplexed production of capillary columns

      Müller-Reif, J. B., Hansen, F. M., Schweizer, L., Treit, P. V., Geyer, P. E. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 10 p., 100082.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. A proteomic atlas of the neointima identifies novel druggable targets for preventive therapy

      Wierer, M., Werner, J., Wobst, J., Kastrati, A., Cepele, G., Aherrahrou, R., Sager, H. B., Erdmann, J., Dichgans, M., Flockerzi, V., Civelek, M., Dietrich, A., Mann, Matthias, Schunkert, H. & Kessler, T., 8 Apr 2021, (E-pub ahead of print) In: European Heart Journal.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. AlphaTims: Indexing Trapped Ion Mobility Spectrometry-TOF Data for Fast and Easy Accession and Visualization

      Willems, S., Voytik, E., Skowronek, P., Strauss, Maximilian & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, p. 100149

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Artificial intelligence for proteomics and biomarker discovery

      Mann, Matthias, Kumar, C., Zeng, W. & Strauss, M. T., 18 Aug 2021, In: Cell Systems. 12, 8, p. 759-770 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    5. Published

      Cohort profile: the MUNICH Preterm and Term Clinical study (MUNICH-PreTCl), a neonatal birth cohort with focus on prenatal and postnatal determinants of infant and childhood morbidity

      Pangratz-Fuehrer, S., Genzel-Boroviczény, O., Bodensohn, W. E., Eisenburger, R., Scharpenack, J., Geyer, P. E., Müller-Reif, J. B., van Hagen, N., Müller, A. M., Jensen, Majken Karoline, Klein, C., Mann, Matthias & Nussbaum, C., 2021, In: BMJ Open. 11, 6, 13 p., e050652.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Data-independent acquisition method for ubiquitinome analysis reveals regulation of circadian biology

      Hansen, F. M., Tanzer, M. C., Brüning, F., Bludau, I., Stafford, C., Schulman, B. A., Robles, M. S., Karayel, O. & Mann, Matthias, 11 Jan 2021, In: Nature Communications. 12, 1, p. 254

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Deep learning the collisional cross sections of the peptide universe from a million experimental values

      Meier, F., Köhler, N. D., Brunner, A. D., Wanka, J. M. H., Voytik, E., Strauss, M. T., Theis, F. J. & Mann, Matthias, 2021, In: Nature Communications. 12, 12 p., 1185.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Deep muscle-proteomic analysis of freeze-dried human muscle biopsies reveals fiber type-specific adaptations to exercise training

      Deshmukh, Atul Shahaji, Steenberg, D. E., Hostrup, Morten, Birk, Jesper Bratz, Larsen, Jeppe Kjærgaard, Santos, A., Kjøbsted, Rasmus, Hingst, J. R., Schéele, Camilla Charlotte Nielsen, Murgia, M., Kiens, Bente, Richter, Erik A., Mann, Matthias & Wojtaszewski, Jørgen F P, 2021, In: Nature Communications. 12, 15 p., 304.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Defining NASH from a multi-omics systems biology perspective

      Niu, Lili, Sulek, K., Vasilopoulou, C. G., Santos, A., Albrechtsen, Nicolai Jacob Wewer, Rasmussen, Simon, Meier, F. & Mann, Matthias, 2021, In: Journal of Clinical Medicine. 10, 20, 22 p., 4673.

      Research output: Contribution to journal › Review › Research › peer-review

    10. Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation

      Hoefig, K. P., Reim, A., Gallus, C., Wong, E. H., Behrens, G., Conrad, C., Xu, M., Kifinger, L., Ito-Kureha, T., Defourny, K. A. Y., Geerlof, A., Mautner, J., Hauck, S. M., Baumjohann, D., Feederle, R., Mann, Matthias, Wierer, M., Glasmacher, E. & Heissmeyer, V., 1 Sep 2021, In: Nature Communications. 12, 1, p. 5208

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains

      Nagao, H., Cai, W., Albrechtsen, Nicolai Jacob Wewer, Steger, M., Batista, T. M., Pan, H., Dreyfuss, J. M., Mann, Matthias & Kahn, C. R., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 17, e2019474118.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Ethical Principles, Constraints and Opportunities in Clinical Proteomics

      Porsdam Mann, Sebastian, Treit, P. V., Geyer, P. E., Omenn, G. S. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 14 p., 100046.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme

      Sherpa, D., Chrustowicz, J., Qiao, S., Langlois, C. R., Hehl, L. A., Gottemukkala, K. V., Hansen, F. M., Karayel, O., von Gronau, S., Prabu, J. R., Mann, Matthias, Alpi, A. F. & Schulman, B. A., 22 Apr 2021, (E-pub ahead of print) In: Molecular Cell.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes

      Dall, M., Hassing, Anna Skab, Niu, Lili, Nielsen, Thomas Svava, Ingerslev, L. R., Sulek, K., Trammell, Sam, Gillum, M. P., Barrès, Romain, Larsen, Steen, Poulsen, Steen Seier, Mann, Matthias, Ørskov, Cathrine & Treebak, Jonas Thue, 2021, In: Journal of Biological Chemistry. 297, 6, 26 p., 101388.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      High-resolution serum proteome trajectories in COVID-19 reveal patient-specific seroconversion

      Geyer, P. E., Arend, F. M., Doll, S., Louiset, M., Virreira Winter, S., Müller-Reif, J. B., Torun, F. M., Weigand, M., Eichhorn, P., Bruegel, M., Strauss, M. T., Holdt, L. M., Mann, Matthias & Teupser, D., 2021, In: EMBO Molecular Medicine. 13, 8, 16 p., e14167.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

      Andersen, Jens Velde, Skotte, Niels Henning, Christensen, S. K., Polli, F. S., Shabani, M., Markussen, K. H., Haukedal, H., Westi, Emil Winther, Diaz-delCastillo, M., Sun, R. C., Kohlmeier, Kristi Anne, Schousboe, Arne, Gentry, M. S., Tanila, H., Freude, Kristine, Aldana, Blanca, Mann, Matthias & Waagepetersen, Helle S., 2021, In: Cell Death & Disease. 12, 11, 13 p., 954 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Homology-directed repair protects the replicating genome from metabolic assaults

      Somyajit, K., Spies, J., Coscia, F., Kirik, U., Rask, M., Lee, J., Neelsen, K. J., Mund, Andreas, Jensen, Lars Juhl, Paull, T. T., Mann, Matthias & Lukas, Jiri, 2021, In: Developmental Cell. 56, 4, p. 461-477.e7

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Identification of covalent modifications regulating immune signaling complex composition and phenotype

      Frauenstein, A., Ebner, S., Hansen, F. M., Sinha, A., Phulphagar, K., Swatek, K., Hornburg, D., Mann, Matthias & Meissner, F., Jul 2021, In: Molecular Systems Biology. 17, 7, p. e10125

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Identification of the transcription factor MAZ as a regulator of erythropoiesis

      Deen, D., Butter, F., Daniels, D. E., Ferrer-Vicens, I., Ferguson, D. C. J., Holland, M. L., Samara, V., Sloane-Stanley, J. A., Ayyub, H., Mann, Matthias, Frayne, J., Garrick, D. & Vernimmen, D., 10 Aug 2021, In: Blood advances. 5, 15, p. 3002-3015 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers

      Mayr, C. H., Simon, L. M., Leuschner, G., Ansari, M., Schniering, J., Geyer, P. E., Angelidis, I., Strunz, M., Singh, P., Kneidinger, N., Reichenberger, F., Silbernagel, E., Böhm, S., Adler, H., Lindner, M., Maurer, B., Hilgendorff, A., Prasse, A., Behr, J., Mann, M. & 3 others, Eickelberg, O., Theis, F. J. & Schiller, H. B., 2021, In: EMBO Molecular Medicine. e12871.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Interaction of 7SK with the Smn complex modulates snRNP production

      Ji, C., Bader, J., Ramanathan, P., Hennlein, L., Meissner, F., Jablonka, S., Mann, Matthias, Fischer, U., Sendtner, M. & Briese, M., 2021, In: Nature Communications. 12, 1, 15 p., 1278.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.Z Acetylation at Regulatory Regions

      Procida, T., Friedrich, T., Jack, A. P. M., Peritore, M., Bönisch, C., Eberl, H. C., Daus, N., Kletenkov, K., Nist, A., Stiewe, T., Borggrefe, T., Mann, Matthias, Bartkuhn, M. & Hake, S. B., 12 Jan 2021, In: International Journal of Molecular Sciences. 22, 2

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

      Kruse, T., Benz, C., Garvanska, D. H., Lindqvist, R., Mihalic, F., Coscia, F., Inturi, R., Sayadi, A., Simonetti, L., Nilsson, E., Ali, M., Kliche, J., Moliner Morro, A., Mund, A., Andersson, E., McInerney, G., Mann, M., Jemth, P., Davey, N. E., Överby, A. K. & 2 others, Nilsson, Jakob & Ivarsson, Y., 2021, In: Nature Communications. 12, 1, 13 p., 6761.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

      Liwocha, J., Krist, D. T., van der Heden van Noort, G. J., Hansen, F. M., Truong, V. H., Karayel, O., Purser, N., Houston, D., Burton, N., Bostock, M. J., Sattler, M., Mann, Matthias, Harrison, J. S., Kleiger, G., Ovaa, H. & Schulman, B. A., Mar 2021, In: Nature Chemical Biology. 17, 3, p. 272-279 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Loss of full-length hnRNP R isoform impairs DNA damage response in motoneurons by inhibiting Yb1 recruitment to chromatin

      Ghanawi, H., Hennlein, L., Zare, A., Bader, J., Salehi, S., Hornburg, D., Ji, C., Sivadasan, R., Drepper, C., Meissner, F., Mann, Matthias, Jablonka, S., Briese, M. & Sendtner, M., 2021, In: Nucleic Acids Symposium Series. 49, 21, p. 12284-12305 22 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 5650809