Marie Sophie Isidor
Assistant Professor
Emanuelli Group
Blegdamsvej 3B, Mærsk Tårnet, 7. sal
2200 København N.
- 2024
- E-pub ahead of print
Functional genomic screens with death rate analyses reveal mechanisms of drug action
Honeywell, M. E., Isidor, Marie Sophie, Harper, N. W., Fontana, R. E., Birdsall, G. A., Cruz-Gordillo, P., Porto, S. A., Jerome, M., Fraser, C. S., Sarosiek, K. A., Guertin, D. A., Spinelli, J. B. & Lee, M. J., 2024, (E-pub ahead of print) In: Nature Chemical Biology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MCT1 helps brown fat suck up succinate
Lund, Jens, Isidor, Marie Sophie & Gerhart-Hines, Zach, 2024, In: Nature Metabolism. 6, p. 387–388Research output: Contribution to journal › Letter › Research › peer-review
- 2023
- Published
Full activation of thermogenesis in brown adipocytes requires Basigin action
Rupar, K., Isidor, Marie Sophie, Argemi Muntadas, Lidia, Agueda Oyarzabal, Marina, Plucinska, Kaja, Brown, E. L., Mattanovich, M., Bossi, Simone, Tozzi, M., Tandio, David, Petersen, P. S. S., Henriksen, T. I., Trošt, K., Hansen, Jacob B., Gerhart-Hines, Zach, Nielsen, S., Moritz, Thomas & Emanuelli, Brice, 2023, In: F E B S Journal. 290, 10, p. 2673-2691Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions
Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, , 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Dynamic interplay between Afadin S1795 phosphorylation and diet regulates glucose homeostasis in obese mice
Tozzi, M., Brown, E. L., Petersen, P. S., Lundh, M., Isidor, Marie Sophie, Plucinska, Kaja, Nielsen, Thomas Svava, Agueda Oyarzabal, Marina, Small, Lewin Barkla, Treebak, Jonas Thue & Emanuelli, Brice, 2022, In: The Journal of Physiology. 600, 4, p. 885-902Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance rewires the metabolic gene program and glucose utilization in human white adipocytes
Isidor, Marie Sophie, Dong, W., Servin-Uribe, R. I., Villarroel, J., Altıntaş, Ali, Ayala-Sumuano, J. T., Varela-Echavarría, A., Barrès, Romain, Stephanopoulos, G., Macotela, Y. & Emanuelli, Brice, 2022, In: International Journal of Obesity. 46, 3, p. 535-543Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, , 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment
Rabiee, A., Plucinska, Kaja, Isidor, Marie Sophie, Brown, E. L., Tozzi, M., Sidoli, S., Petersen, P. S. S., Agueda Oyarzabal, Marina, Torsetnes, S. B., Chehabi, G. N., Lundh, M., Altıntaş, Ali, Barrès, Romain, Jensen, O. N., Gerhart-Hines, Zach & Emanuelli, Brice, 2021, In: Molecular Metabolism. 44, 17 p., 101137.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Next Generation Diabetes Scientists Shape Global Research Culture: A reflective proposal from postdoctoral researchers in diabetes research
Gonzalez-Franquesa, A., Carrasquilla Lopez, G. D., Mamidi, A., Ghiasi, S. M., Juel, H. B., Falk, S., Isidor, M. S., Gillberg, L. M. E., Huang, L. O., Quist, J. S., Knudsen, J. R., Quaranta, R., Tozzi, M., Mikkelsen, R. B., Dall, M., Drag, M. H., Small, L. B., Altıntaş, A., Osborne, B., Modvig, I. M. & 11 others, , 2020, In: Acta Physiologica. 229, 2, 5 p., e13455.Research output: Contribution to journal › Comment/debate › Research
- Published
Pyruvate kinase M2 represses thermogenic gene expression in brown adipocytes
Isidor, Marie Sophie, Winther, Sally, Markussen, L. K., Basse, A. L., Quistorff, B., Nedergaard, J., Emanuelli, Brice & Hansen, Jacob B., 2020, In: FEBS Letters. 594, 7, p. 1218-1225Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue
Lundh, M., Petersen, P. S., Isidor, Marie Sophie, Kazoka-Sørensen, D. N., Plucinska, Kaja, Shamsi, F., Ørskov, Cathrine, Tozzi, M., Brown, E. L., Andersen, E., Ma, Tao, Müller, U. A., Barrès, Romain, Kristiansen, V. B., Gerhart-Hines, Zach, Tseng, Y. & Emanuelli, Brice, 2019, In: EMBO Reports. 20, 8, e48216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overexpression of cyclooxygenase-2 in adipocytes reduces fat accumulation in inguinal white adipose tissue and hepatic steatosis in high-fat fed mice
Danneskiold-Samsøe, Niels Banhos, Sonne, Si Brask, Larsen, J. M., Hansen, Ann Normann, Fjære, E., Isidor, Marie Sophie, Petersen, S., Henningsen, J., Severi, I., Sartini, L., Schobers, Y., Wolf, J., Nockhers, W. A., Wolfrum, C., Cinti, S., Sina, C., Hansen, Jacob B., Madsen, L., Brix, S. & Kristiansen, Karsten, 2019, In: Scientific Reports. 9, 13 p., 8979.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption
Winther, Sally, Isidor, Marie Sophie, Basse, A. L., Skjoldborg, N., Cheung, A., Quistorff, B. & Hansen, Jacob B., 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 3, p. E214-E223 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
MCT1 and MCT4 expression and lactate flux activity increase during white and brown adipogenesis and impact adipocyte metabolism
Petersen, C., Nielsen, M. D., Andersen, E. S., Basse, A. L., Isidor, Marie Sophie, Markussen, L. K., Viuff, B. M., Lambert, Ian Henry, Hansen, Jacob B. & Pedersen, Stine Helene Falsig, 12 Oct 2017, In: Scientific Reports. 7, 1, 13 p., 13101.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA
Lundh, M., Plucinska, Kaja, Isidor, Marie Sophie, Petersen, P. S. S. & Emanuelli, Brice, Oct 2017, In: Molecular Metabolism. 6, 10, p. 1313-1320 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of immortalized human brown and white pre-adipocyte cell models from a single donor
Markussen, L. K., Isidor, Marie Sophie, Breining, P., Andersen, E. S., Rasmussen, N. E., Petersen, L. I., Pedersen, S. B., Richelsen, B. & Hansen, Jacob B., 28 Sep 2017, In: PLoS ONE. 12, 9, 17 p., e0185624.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of glycolysis in brown adipocytes by HIF-1α
Basse, A. L., Isidor, Marie Sophie, Winther, Sally, Skjoldborg, N. B., Murholm, M., Andersen, E. S., Pedersen, S. B., Wolfrum, C., Quistorff, B. & Hansen, Jacob B., 22 Jun 2017, In: Scientific Reports. 7, 15 p., 4052.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
An siRNA-based method for efficient silencing of gene expression in mature brown adipocytes
Isidor, Marie Sophie, Winther, Sally, Basse, A. L., Petersen, M. C. H., Cannon, B., Nedergaard, J. & Hansen, Jacob B., 2016, In: Adipocyte. 5, 2, p. 175-185 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
ERRγ enhances UCP1 expression and fatty acid oxidation in brown adipocytes
Dixen, K., Basse, A. L., Murholm, M., Isidor, Marie Sophie, Hansen, L. H. L., Petersen, M. C. H., Madsen, L., Petrovic, N., Nedergaard, J., Quistorff, B. & Hansen, Jacob B., 2013, In: Obesity. 21, 3, p. 516-524 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1) reduces mortality and improves lung function in a model of experimental obstructive lung disease in female mice
Viby, N., Isidor, Marie Sophie, Buggeskov, K. B., Poulsen, Steen Seier, Hansen, Jacob B. & Kissow, Hannelouise, 2013, In: Endocrinology. 154, 12, p. 4503-4511 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Retinoic acid has different effects on UCP1 expression in mouse and human adipocytes
Murholm, M., Isidor, Marie Sophie, Basse, A. L., Winther, Sally, Sørensen, C., Skovgaard-Petersen, J., Nielsen, M. M., Hansen, A. S., Quistorff, B. & Hansen, Jacob B., 2013, In: B M C Cell Biology. 14, 41, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38008592
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Retinoic acid has different effects on UCP1 expression in mouse and human adipocytes
Research output: Contribution to journal › Journal article › Research › peer-review
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264
downloads
Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
237
downloads
Regulation of glycolysis in brown adipocytes by HIF-1α
Research output: Contribution to journal › Journal article › Research › peer-review
Published