Lars Hviid

Lars Hviid

Professor

Member of:

  • SURFACE team


  1. 2016
  2. Published

    Immunoglobulin M: restrainer of inflammation and mediator of immune evasion by Plasmodium falciparum malaria

    Pleass, R. J., Moore, S. C., Stevenson, L. & Hviid, Lars, Feb 2016, In: Trends in Parasitology. 32, 2, p. 108-119 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  3. 2015
  4. Published

    α2-macroglobulin can crosslink multiple Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) molecules and may facilitate adhesion of parasitized erythrocytes

    Stevenson, L., Laursen, E., Cowan, G. J., Bandoh, B., Barfod, Lea Klingenberg, Cavanagh, D. R., Andersen, G. R. & Hviid, Lars, Jul 2015, In: P L o S Pathogens. 11, 7, p. 1-19 19 p., e1005022.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Investigating the function of Fc -specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting

    Stevenson, L., Huda, P., Jeppesen, A., Laursen, E. T. F., Rowe, J. A., Craig, A., Streicher, W., Barfod, Lea Klingenberg & Hviid, Lars, Jun 2015, In: Cellular Microbiology. 17, 6, p. 819-31 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    PfEMP1 – a parasite protein family of key importance in Plasmodium falciparum malaria immunity and pathogenesis

    Hviid, Lars & Jensen, Anja Ramstedt, Apr 2015, Advances in Parasitology. Rollinson, D. & Stothard, J. R. (eds.). Vol. 88. p. 51-84 34 p. (Advances in Parasitology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  7. Published

    Trying to remember: immunological B cell memory to malaria

    Hviid, Lars, Barfod, Lea Klingenberg & Fowkes, F. J. I., Mar 2015, In: Trends in Parasitology. 31, 3, p. 89-94 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Plasmodium falciparum-infected erythrocyte knob density is linked to the PfEMP1 variant expressed

    Subramani, R., Quadt, K., Jeppesen, A. E., Hempel, C., Petersen, J. E. V., Hassenkam, Tue, Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: mBio. 6, 5, 7 p., e01456-15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Multiple Plasmodium falciparum erythrocyte membrane protein 1 variants per genome can bind IgM via its Fc fragment Fcμ

    Jeppesen, A., Ditlev, S. B., Soroka, V., Stevenson, E. K., Turner, Louise, Dzikowski, R., Hviid, Lars & Barfod, Lea Klingenberg, 2015, In: Infection and Immunity. 83, 10, p. 3972-81 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2014
  11. Published

    Kinetics of B Cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites

    Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, 1 Jun 2014, In: Journal of Immunology. 192, 11, p. 5236-44 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    B-cell responses to pregnancy-restricted and -unrestricted Plasmodium falciparum erythrocyte membrane protein 1 antigens in Ghanaian women naturally exposed to malaria parasites

    Ampomah, P., Stevenson, L., Ofori, M. F., Barfod, Lea Klingenberg & Hviid, Lars, May 2014, In: Infection and Immunity. 82, 5, p. 1860-71 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites

    Sleebs, B. E., Lopaticki, S., Marapana, D. S., O'Neill, M. T., Rajasekaran, P., Gazdik, M., Günther, S., Whitehead, L. W., Lowes, K. N., Barfod, Lea Klingenberg, Hviid, Lars, Shaw, P. J., Hodder, A. N., Smith, B. J., Cowman, A. F. & Boddey, J. A., 2014, In: P L o S Biology. 12, 7, p. e1001897

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Modeling malaria infection and immunity against variant surface antigens in Príncipe island, West Africa

    Bandeiras, C., Trovoada, M. J., Gonçalves, L. A., Marinho, C. R. F., Turner, Louise, Hviid, Lars, Penha-Gonçalves, C. & Gomes, M. G. M., 2014, In: PloS one. 9, 2, p. e88110

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2013
  16. Published

    Cytokine response to pregnancy-associated recrudescence of Plasmodium berghei infection in mice with pre-existing immunity to malaria

    Megnekou, R., Staalsø, Trine & Hviid, Lars, 1 Nov 2013, In: Malaria Journal. 12, 1, p. 387

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Malaria

    Riley, E. M., Hviid, Lars & Theander, Thor Grundtvig, 22 Oct 2013, Parasitic Infections and the Immune System. Elsevier Science Inc., p. 119-143 25 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  18. Published

    A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies

    Bengtsson, A., Joergensen, L., Rask, T. S., Olsen, R. W., Andersen, M. A., Turner, Louise, Theander, Thor Grundtvig, Hviid, Lars, Higgins, M. K., Craig, A., Brown, A. & Jensen, Anja Ramstedt, 2013, In: Journal of Immunology. 190, 1, p. 240-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Plasmodium falciparum Expressing Domain Cassette 5 Type PfEMP1 (DC5-PfEMP1) Bind PECAM1

    Berger, S. S., Turner, Louise, Wang, Christian William, Petersen, J. E. V., Kraft, M., Lusingu, J. P. A., Mmbando, B., Marquard, A. M., Bengtsson, D. B. A. C., Hviid, Lars, Nielsen, Morten Agertoug, Theander, Thor Grundtvig & Lavstsen, Thomas, 2013, In: PloS one. 8, 7, p. e69117

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Transfected HEK293 Cells Expressing Functional Recombinant Intercellular Adhesion Molecule 1 (ICAM-1) - A Receptor Associated with Severe Plasmodium falciparum Malaria

    Bengtsson, A., Joergensen, L., Barbati, Z. R., Craig, A., Hviid, Lars & Jensen, Anja Ramstedt, 2013, In: PLOS ONE. 8, 7, p. e69999

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2012
  22. Published

    Aligned hemozoin crystals in curved clusters in malarial red blood cells revealed by nanoprobe X-ray Fe fluorescence and diffraction

    Kapishnikov, S., Berthing, T., Hviid, Lars, Dierolf, M., Menzel, A., Pfeiffer, F., Als-Nielsen, Jens & Leiserowitz, L., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 28, p. 11184-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia

    Boeuf, P. S., Loizon, S., Awandare, G. A., Tetteh, J. K., Addae, M. M., Adjei, G. O., Goka, B., Kurtzhals, Jørgen, Puijalon, O., Hviid, Lars, Akanmori, B. D. & Behr, C., 2012, In: Malaria Journal. 11, 1, p. 253

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The density of knobs on Plasmodium falciparum-infected erythrocytes depends on developmental age and varies among isolates

    Quadt, K. A., Barfod, Lea Klingenberg, Andersen, D., Bruun, J., Gyan, B., Hassenkam, Tue, Ofori, M. F. & Hviid, Lars, 2012, In: P L o S One. 7, 9, p. e45658

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2011
  26. Published

    Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1

    Barfod, Lea Klingenberg, Dalgaard, M. B., Pleman, S. T., Ofori, M. F., Pleass, R. J. & Hviid, Lars, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 30, p. 12485-90 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The case for PfEMP1-based vaccines to protect pregnant women against Plasmodium falciparum malaria

    Hviid, Lars, 2011, In: Expert Review of Vaccines. 10, 10, p. 1405-14 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2010
  29. Published

    Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants

    Barfod, Lea Klingenberg, Dobrilovic, T., Magistrado, P., Khunrae, P., Viwami, F., Bruun, J., Dahlbäck, M., Bernasconi, N. L., Fried, M., John, D., Duffy, P. E., Salanti, Ali, Lanzavecchia, A., Lim, C. T., Ndam, N. T., Higgins, M. K. & Hviid, Lars, 2010, In: Journal of Immunology. 185, 12, p. 7553-61 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Hierarchical, domain type-specific acquisition of antibodies to Plasmodium falciparum erythrocyte membrane protein 1 in Tanzanian children

    Cham, G. K. K., Turner, Louise, Kurtis, J. D., Mutabingwa, T., Fried, M., Jensen, Anja Ramstedt, Lavstsen, Thomas, Hviid, Lars, Duffy, P. E. & Theander, Thor Grundtvig, 2010, In: Infection and Immunity. 78, 11, p. 4653-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Immune selection and within-host competition can structure the repertoire of variant surface antigens in Plasmodium falciparum -a mathematical model

    van Noort, S. P., Nunes, M. C., Weedall, G. D., Hviid, Lars & Gomes, M. G. M., 2010, In: PLoS ONE. 5, 3, p. e9778

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Of mice and women: rodent models of placental malaria

    Hviid, Lars, Marinho, C. R. F., Staalsø, Trine & Penha-Gonçalves, C., 2010, In: Trends in Parasitology. 26, 8, p. 412-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs

    Joergensen, L. M., Salanti, Ali, Dobrilovic, T., Barfod, Lea Klingenberg, Hassenkam, Tue, Theander, Thor Grundtvig, Hviid, Lars & Arnot, D. E., 2010, In: Malaria Journal. 9, 1, p. 100

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    The role of Plasmodium falciparum variant surface antigens in protective immunity and vaccine development

    Hviid, Lars, 2010, In: Human Vaccines. 6, 1, p. 84-89 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. 2009
  36. Published

    Human monoclonal IgG selection of Plasmodium falciparum for the expression of placental malaria-specific variant surface antigens

    Soerli, J., Barfod, Lea Klingenberg, Lavstsen, Thomas, Bernasconi, N. L., Lanzavecchia, A. & Hviid, Lars, 2009, In: Parasite Immunology. 31, 6, p. 341-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Pregnancy-associated malaria in a rural community of Ghana

    Ofori, M., Ansah, E., Agyepong, I., Ofori-Adjei, D., Hviid, Lars & Akanmori, B., 2009, In: Ghana Medical Journal. 43, 1, p. 13-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Unraveling the impact of malaria exposure before birth

    Hviid, Lars, 2009, In: PLoS Medicine. 6, 7, p. e1000117

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Variant-specific immunity to Plasmodium berghei in pregnant mice

    Megnekou, R., Hviid, Lars & Staalsoe, T., 2009, In: Infection and Immunity. 77, 5, p. 1827-34 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. 2008
  41. Published

    CD36 selection of 3D7 Plasmodium falciparum associated with severe childhood malaria results in reduced VAR4 expression

    Magistrado, P., Staalsoe, T., Theander, Thor Grundtvig, Hviid, Lars & Jensen, Anja Ramstedt, 2008, In: Malaria Journal. 7, 1, p. 204

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Differences in human antibody reactivity to Plasmodium falciparum variant surface antigens are dependent on age and malaria transmission intensity in northeastern Tanzania

    Vestergaard, L. S., Lusingu, J. P., Nielsen, Morten Agertoug, Mmbando, B. P., Dodoo, D., Akanmori, B. D., Alifrangis, Michael, Bygbjerg, Ib Christian, Lemnge, M. M., Staalsoe, T., Hviid, Lars & Theander, Thor Grundtvig, 2008, In: Infection and Immunity. 76, 6, p. 2706-14 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Malaria vaccines: immunity, models and monoclonal antibodies

    Hviid, Lars & Barfod, Lea Klingenberg, 2008, In: Trends in Parasitology. 24, 9, p. 392-395 3 p.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes

    Magistrado, P., Salanti, Ali, Tuikue Ndam, N. G., Mwakalinga, S. B., Resende, M., Dahlbäck, M., Hviid, Lars, Lusingu, J., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2008, In: Journal of Infectious Diseases.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2007
  46. Published

    Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin

    Nielsen, Morten Agertoug, Resende, M., Alifrangis, Michael, Turner, Louise, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2007, In: Experimental Parasitology. 117, 1, p. 1-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Adhesion specificities of Plasmodium falciparum-infected erythrocytes involved in the pathogenesis of pregnancy-associated malaria

    Hviid, Lars, 2007, In: American Journal of Pathology. 170, 6, p. 1817-9 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  48. Published

    Changes in var gene mRNA levels during erythrocytic development in two phenotypically distinct Plasmodium falciparum parasites

    Dahlbäck, M., Lavstsen, Thomas, Salanti, Ali, Hviid, Lars, Arnot, D. E., Theander, Thor Grundtvig & Nielsen, Morten Agertoug, 2007, In: Malaria Journal. 6, p. 78

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Developing Plasmodium falciparum malaria vaccines for populations living in areas with stable parasite transmission

    Hviid, Lars & Theander, Thor Grundtvig, 2007, In: International Journal of Biotechnology. 9, 3/4, p. 292-300 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Development of vaccines against Plasmodium falciparum malaria: taking lessons from naturally acquired protective immunity

    Hviid, Lars, 2007, In: Microbes and Infection. 9, 6, p. 772-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA

    Barfod, Lea Klingenberg, Bernasconi, N. L., Dahlbäck, M., Jarrossay, D., Andersen, P. H., Salanti, Ali, Ofori, M. F., Turner, Louise, Resende, M., Nielsen, Morten Agertoug, Theander, Thor Grundtvig, Sallusto, F., Lanzavecchia, A. & Hviid, Lars, 2007, In: Molecular Microbiology. 63, 2, p. 335-47 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Immunoglobulin G antibody reactivity to a group A Plasmodium falciparum erythrocyte membrane protein 1 and protection from P. falciparum malaria

    Magistrado, P. A., Lusingu, J., Vestergaard, L. S., Lemnge, M., Lavstsen, Thomas, Turner, Louise, Hviid, Lars, Jensen, Anja Ramstedt & Theander, Thor Grundtvig, 2007, In: Infection and Immunity. 75, 5, p. 2415-20 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Malaria in pregnancy: pathogenesis and immunity

    Rogerson, S. J., Hviid, Lars, Duffy, P. E., Leke, R. F. G. & Taylor, D. W., 2007, In: Lancet Infectious Diseases. 7, 2, p. 105-17 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Selective activation of TCR-G¿ cells in endemic Burkitt's lymphoma

    Futagbi, G., Welbeck, J. E., Tetteh, J. K. A., Hviid, Lars & Akanmori, B. D., 2007, In: Malaria Journal. 6, p. 69

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    VAR2CSA and protective immunity against pregnancy-associated Plasmodium falciparum malaria

    Hviid, Lars & Salanti, Ali, 2007, In: Parasitology. 134, Pt 13, p. 1871-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Vß profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability

    Loizon, S., Boeuf, P., Tetteh, J. K. A., Goka, B., Obeng-Adjei, G., Kurtzhals, J. A. L., Rogier, C., Akanmori, B. D., Mercereau-Puijalon, O., Hviid, Lars & Behr, C., 2007, In: Microbes and Infection. 9, 11, p. 1252-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. 2006
  58. Published

    Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes

    Barfod, Lea Klingenberg, Nielsen, Morten Agertoug, Turner, Louise, Dahlbäck, M., Jensen, Anja Ramstedt, Hviid, Lars, Theander, Thor Grundtvig & Salanti, Ali, 2006, In: Infection and Immunity. 74, 7, p. 4357-60 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo

    Haase, R. N., Megnekou, R., Lundquist, M., Ofori, M. F., Hviid, Lars & Staalsoe, T., 2006, In: Infection and Immunity. 74, 5, p. 3035-8 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration

    Dahlbäck, M., Rask, T. S., Andersen, P. H., Nielsen, Morten Agertoug, Ndam, N. T., Resende, M., Turner, Louise, Deloron, P., Hviid, Lars, Lund, O., Pedersen, A. G., Theander, Thor Grundtvig & Salanti, Ali, 2006, In: PLoS Pathogens. 2, 11, p. e124

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Late recrudescence of Plasmodium falciparum malaria in pregnancy

    Hviid, Lars & Staalsoe, T., 2006, In: International Journal of Infectious Diseases. 10, 5, p. 412

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 3620