Lars Allan Larsen

Lars Allan Larsen

Professor

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    1 - 83 out of 83Page size: 100
    1. 2024
    2. Published

      TBX5 variants and cardiac phenotype: A systematic review of the literature and a novel variant

      Møller Nielsen, A. K., Dehn, A. M., Hjortdal, Vibeke Elisabeth & Larsen, Lars Allan, 2024, In: European Journal of Medical Genetics. 68, 6 p., 104920.

      Research output: Contribution to journal › Review › Research › peer-review

    3. Published

      Pericardial delta like non-canonical NOTCH ligand 1 (Dlk1) augments fibrosis in the heart through epithelial to mesenchymal transition

      Jensen, C. H., Johnsen, R. H., Eskildsen, T., Baun, C., Ellman, D. G., Fang, S., Bak, S. T., Hvidsten, S., Larsen, Lars Allan, Rosager, A. M., Riber, L. P., Schneider, M., De Mey, J., Thomassen, Mads, Burton, M., Uchida, S., Laborda, J. & Andersen, D. C., 2024, In: Clinical and Translational Medicine. 14, 2, 18 p., e1565.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. 2023
    5. Published

      The genetic background of hydrocephalus in a population-based cohort: implication of ciliary involvement

      Munch, Tina Nørgaard, Hedley, P. L., Hagen, C. M., Baekvad-Hansen, M., Geller, F., Bybjerg-Grauholm, J., Nordentoft, Merete, Borglum, A. D., Werge, Thomas, Melbye, M., Hougaard, D. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Christiansen, M., 2023, In: Brain Communications. 5, 1, 14 p., fcad004.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. 2022
    7. Published

      Comparison of Outcome in Patients With Familial Versus Spontaneous Atrial Septal Defect

      Nielsen, A. K. M., Ellesøe, S. G., Larsen, Lars Allan, Hjortdal, Vibeke Elisabeth & Nyboe, C., 2022, In: The American Journal of Cardiology. 173, p. 128-131

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      MCPH1: A Novel Case Report and a Review of the Literature

      Caraffi, S. G., Pollazzon, M., Farooq, M., Fatima, A., Larsen, Lars Allan, Zuntini, R., Napoli, M. & Garavelli, L., 2022, In: Genes. 13, 4, 634.

      Research output: Contribution to journal › Review › Research › peer-review

    9. 2021
    10. Published

      Integrative analysis of genomic variants reveals new associations of candidate haploinsufficient genes with congenital heart disease

      Audain, E., Wilsdon, A., Breckpot, J., Izarzugaza, J. M. G., Fitzgerald, T. W., Kahlert, A. K., Sifrim, A., Wünnemann, F., Perez-Riverol, Y., Abdul-Khaliq, H., Bak, M., Bassett, A. S., Benson, W. D., Berger, F., Daehnert, I., Devriendt, K., Dittrich, S., Daubeney, P. E. F., Garg, V., Hackmann, K. & 30 others, Hoff, K., Hofmann, P., Dombrowsky, G., Pickardt, T., Bauer, U., Keavney, B. D., Klaassen, S., Kramer, H. H., Marshall, C. R., Milewicz, D. M., Lemaire, S., Coselli, J. S., Mitchell, M. E., Tomita-Mitchell, A., Prakash, S. K., Stamm, K., Stewart, A. F. R., Silversides, C. K., Siebert, R., Stiller, B., Rosenfeld, J. A., Vater, I., Postma, A. V., Caliebe, A., Brook, J. D., Andelfinger, G., Hurles, M. E., Thienpont, B., Larsen, Lars Allan & Hitz, M. P., 2021, In: PLOS Genetics. 17, 7, e1009679.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Mutation burden in patients with small unrepaired atrial septal defects☆

      Nielsen, A. K. M., Nyboe, C., Ovesen, A. S. L., Udholm, S., Larsen, M. M. M., Hjortdal, Vibeke Elisabeth & Larsen, Lars Allan, 2021, In: International Journal of Cardiology Congenital Heart Disease. 4, 6 p., 100164.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. 2020
    13. Published

      RRP7A links primary microcephaly to dysfunction of ribosome biogenesis, resorption of primary cilia, and neurogenesis

      Farooq, M., Lindbæk, L., Krogh, N., Doganli, C., Keller, C., Mönnich, M., Gonçalves, A. B., Sakthivel, S., Mang, Y., Fatima, A., Andersen, V. S., Hussain, M. S., Eiberg, H., Hansen, L., Kjaer, K. W., Gopalakrishnan, J., Pedersen, L. B., Møllgård, K., Nielsen, H., Baig, S. M. & 3 others, Tommerup, Niels, Christensen, Søren Tvorup & Larsen, Lars Allan, 2020, In: Nature Communications. 11, 16 p., 5816.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Systems genetics analysis identifies calcium-signaling defects as novel cause of congenital heart disease

      Izarzugaza, J. M. G., Ellesøe, S. G., Doganli, Canan, Ehlers, Natasja Spring, Dalgaard, M. D., Audain, E., Dombrowsky, G., Banasik, Karina, Sifrim, A., Wilsdon, A., Thienpont, B., Breckpot, J., Gewillig, M., Brook, J. D., Hitz, M., Larsen, Lars Allan, Brunak, Søren & Competence Network for Congenital Heart Defects, Germany, C. N. F. C. H. D. G., 2020, In: Genome Medicine. 12, 1, 13 p., 76.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. 2019
    16. Published

      Haploinsufficiency of ARHGAP42 is associated with hypertension

      Fjorder, A. S., Rasmussen, Malene Bøgehus, Mehrjouy, M. M., Nazaryan, Lusine, Hansen, C., Bak, M., Grarup, Niels, Nørremølle, Anne, Larsen, Lars Allan, drb459, drb459, Hansen, Torben, Tommerup, Niels & Bache, Iben, 2019, In: European Journal of Human Genetics. 27, 8, p. 1296-1303 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Model system identification of novel congenital heart disease gene candidates: focus on RPL13

      Schroeder, A. M., Allahyari, M., Vogler, G., Missinato, M. A., Nielsen, T., Yu, M. S., Theis, J. L., Larsen, Lars Allan, Goyal, P., Rosenfeld, J. A., Nelson, T. J., Olson, T. M., Colas, A. R., Grossfeld, P. & Bodmer, R., 2019, In: Human Molecular Genetics. 28, 23, p. 3954-3969 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Patterns of co-occurrence of congenital heart defects follows distinct patterns

      Ellesøe, S. G., Workman, C. T., Bouvagnet, P., Loffredo, C. A., McBride, K. L., Hinton, R. B., van Engelen, K., Gertsen, E. C., Mulder, B. J. M., Postma, A. V., Anderson, R. H., Hjortdal, Vibeke Elisabeth, Brunak, Søren & Larsen, Lars Allan, 2019, In: European Journal of Human Genetics. 26, p. 106 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    19. 2018
    20. Published

      Familial co-occurrence of congenital heart defects follows distinct patterns

      Ellesøe, S. G., Workman, C. T., Bouvagnet, P., Loffredo, C. A., McBride, K. L., Hinton, R. B., van Engelen, K., Gertsen, E. C., Mulder, B. J. M., Postma, A. V., Anderson, R. H., Hjortdal, V. E., Brunak, Søren & Larsen, Lars Allan, Mar 2018, In: European Heart Journal. 39, 12, p. 1015–1022

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-β/BMP Signaling at the Primary Cilium

      Mönnich, M., Borgeskov, L., Breslin, L., Jakobsen, L., Rogowski, M., Doganli, Canan, Schrøder, J. M., Mogensen, J. B., Blinkenkjær, L., Harder, L. M., Lundberg, E., Geimer, S., Christensen, Søren Tvorup, Andersen, J. S., Larsen, Lars Allan & Pedersen, Lotte Bang, 2018, In: Cell Reports. 22, 10, p. 2584-2592 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Challenges for the sustainability of university-run biobanks

      Kongsholm, Nana Cecilie Halmsted, Christensen, Søren Tvorup, Herrmann, Janne Rothmar, Larsen, Lars Allan, Minssen, Timo, Pedersen, Lotte Bang, Rajam, N., Tommerup, Niels, Tupasela, A. M. & Schovsbo, Jens Hemmingsen, 2018, In: Biopreservation and Biobanking. 16, 4, p. 312-321 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases

      Schmid, F. M., Schou, K. B., Vilhelm, M. J., Holm, M. S., Breslin, L., Farinelli, P., Larsen, Lars Allan, Andersen, J. S., Pedersen, Lotte Bang & Christensen, Søren Tvorup, 2018, In: Journal of Cell Biology. 217, 1, p. 151-161 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development

      Rasmussen, K. K., Skat-Rørdam, Josephine, Andersen, P., Warzecha, C. B., Pye, M., Andersen, T. A., Ajbro, K. D., Bendsen, E., Narimatsu, M., Vilhardt, Frederik, Pedersen, Lotte Bang, Wrana, J. L., Anderson, R. H., Møllgård, Kjeld, Christensen, Søren Tvorup & Larsen, Lars Allan, 2018, In: Scientific Reports. 8, 1, 14 p., 9542.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. 2017
    26. Published

      A novel mutation in CDK5RAP2 gene causes primary microcephaly with speech impairment and sparse eyebrows in a consanguineous Pakistani family

      Abdullah, U., Farooq, M., Mang, Y., Marriam Bakhtiar, S., Fatima, A., Hansen, Lars, Kjaer, K. W., Larsen, Lars Allan, Faryal, S., Tommerup, Niels & Mahmood Baig, S., Dec 2017, In: European Journal of Medical Genetics. 60, 12, p. 627-630 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Patient-specific three-dimensional explant spheroids derived from human nasal airway epithelium: a simple methodological approach for ex vivo studies of primary ciliary dyskinesia

      Marthin, J. K., Stevens, E. M., Larsen, Lars Allan, Christensen, Søren Tvorup & Nielsen, Kim G., 23 Mar 2017, In: Cilia. 6, 9 p., 3.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Mutation of the planar cell polarity gene VANGL1 in adolescent idiopathic scoliosis

      Andersen, M. R., Farooq, M., Rasmussen, K. K., Kjaer, K. W., Simony, A., Christensen, Søren Tvorup & Larsen, Lars Allan, 2017, In: Spine. 42, 12, p. E702–E707 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. 2016
    30. Published

      Familial Atrial Septal Defect and Sudden Cardiac Death: Identification of a Novel NKX2-5 Mutation and a Review of the Literature

      Ellesøe, S. G., Johansen, M. M., Bjerre, J. V., Hjortdal, V. E., Brunak, Søren & Larsen, Lars Allan, 1 May 2016, In: Congenital Heart Disease. 11, 3, p. 283–290 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      A novel splice site mutation in CEP135 is associated with primary microcephaly in a Pakistani family

      Farooq, M., Fatima, A., Mang, Y., Hansen, Lars, Kjaer, K. W., Baig, S. M., Larsen, Lars Allan & Tommerup, Niels, Mar 2016, In: Journal of Human Genetics. 61, 3, p. 271-273 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      How Suitable Are Registry Data for Recurrence Risk Calculations? Validation of Diagnoses on 1,593 Families With Congenital Heart Disease

      Ellesøe, S. G., Jensen, A. B., Ängquist, Lars, Hjortdal, V. E., Larsen, Lars Allan & Brunak, Søren, Mar 2016, In: World journal for pediatric & congenital heart surgery. 7, 2, p. 169-77 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. 2015
    34. Published

      Coordination of TGFβ/BMP signaling is associated with the primary cilium

      Lindbæk, L., Warzecha, C. B., Koefoed, K., Mogensen, J. B., Schmid, F., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2015, In: Cilia. 4, Suppl. 1, 1 p., P17.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    35. 2014
    36. Published

      Brain Barriers and a Subpopulation of Astroglial Progenitors of Developing Human Forebrain Are Immunostained for the Glycoprotein YKL-40

      Holst, Camilla Bjørnbak, Brøchner, Christian Beltoft, Larsen, Lars Allan, Johansen, Julia Sidenius & Møllgård, Kjeld, May 2014, In: Journal of Histochemistry and Cytochemistry. 62, 5, p. 369-88 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Of mice and men: molecular genetics of congenital heart disease

      Andersen, T. A., Troelsen, K. D. L. L. & Larsen, Lars Allan, Apr 2014, In: Cellular and molecular life sciences : CMLS. 71, 8, p. 1327-1352 26 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Sequence analysis of 17 NRXN1 deletions

      Hoeffding, L. K. E., Hansen, T., Ingason, A., Doung, L., Thygesen, J. H., Møller, R. S., Tommerup, Niels, Kirov, G., Rujescu, D., Larsen, Lars Allan & Werge, Thomas, Jan 2014, In: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 165, 1, p. 52-61 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Cilia and coordination of signaling networks during heart development

      Koefoed, K., Veland, I. R., Pedersen, Lotte Bang, Larsen, Lars Allan & Christensen, Søren Tvorup, 2014, In: Organogenesis. 10, 1, p. 108-125 18 p.

      Research output: Contribution to journal › Review › Research › peer-review

    40. 2013
    41. Published

      TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium

      Clement, C. A., Ajbro, K. D., Koefoed, K., Vestergaard, M. L., Veland, I. R., Perestrello Ramos H de Jesus, M., Pedersen, Lotte Bang, Benmerah, A., tcg964, tcg964, Larsen, Lars Allan & Christensen, Søren Tvorup, 2013, In: Cell Reports. 3, 6, p. 1806-1814 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. 2012
    43. Published

      Screening of congenital heart disease patients using multiplex ligation-dependent probe amplification: early diagnosis of syndromic patients

      Sørensen, K. M., El-Segaier, M., Fernlund, E., Errami, A., Bouvagnet, P., Nehme, N., Steensberg, J., Hjortdal, V. E., Soller, M., Behjati, M., Werge, Thomas, Kirchoff, M., Schouten, J., Tommerup, Niels, Andersen, P. S. & Larsen, Lars Allan, Mar 2012, In: American Journal of Medical Genetics. Part A. 158A, 4, p. 720-5 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      YKL-40 is differentially expressed in human embryonic stem cells and in cell progeny of the three germ layers

      Brøchner, Christian Beltoft, Johansen, Julia Sidenius, Larsen, Lars Allan, Bak, M., Mikkelsen, H. B., Byskov, A. G., tcg964, tcg964 & Møllgård, Kjeld, Mar 2012, In: Journal of Histochemistry and Cytochemistry. 60, 3, p. 188-204 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development

      Hansen, K. L., Greenway, S. C., Rosenfeld, J. A., Wakimoto, H., Gorham, J. M., Segrè, A. V., Roberts, A. E., Smoot, L. B., Pu, W. T., C Pereira, A., Mesquita, S. M., Tommerup, Niels, Brunak, Søren, Ballif, B. C., Shaffer, L. G., Donahoe, P. K., Daly, M. J., Seidman, J. G., Seidman, C. E. & Larsen, Lars Allan, 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 35, p. 14035-40 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. 2011
    47. Published

      Kromosomforandringer ved medfødt hjertemisdannelse

      Larsen, Lars Allan, 17 Jan 2011, In: Ugeskrift for Laeger. 173, 3, p. 194-6 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. 2010
    49. Published

      Detecting 22q11.2 deletions by use of multiplex ligation-dependent probe amplification on DNA from neonatal dried blood spot samples

      Sørensen, K. M., Agergaard, P., Olesen, C., Andersen, P. S., Larsen, Lars Allan, Ostergaard, J. R., Schouten, J. P. & Christiansen, M., 2010, In: Journal of Molecular Diagnostics. 12, 2, p. 147-51 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Dissecting spatio-temporal protein networks driving human heart development and related disorders

      Hansen, K. L., Møllgård, K., Greenway, S., Wakimoto, H., Gorham, J. M., Workman, C. T., Bendsen, E., Hansen, N. T., Rigina, O., Roque, F. S., Wiese, C., Christoffels, V. M., Roberts, A. E., Smoot, L. B., Pu, W. T., Donahoe, P. K., Tommerup, N., Brunak, S., Seidman, C. E., Seidman, J. G. & 1 others, Larsen, Lars Allan, 2010, In: Molecular Systems Biology. 6, p. 381

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Haploinsufficiency of TAB2 causes congenital heart defects in humans

      Thienpont, B., Zhang, L., Postma, A. V., Breckpot, J., Tranchevent, L., Van Loo, P., Møllgård, Kjeld, Tommerup, Niels, Bache, Iben, Tümer, Asuman Zeynep, van Engelen, K., Menten, B., Mortier, G., Waggoner, D., Gewillig, M., Moreau, Y., Devriendt, K. & Larsen, Lars Allan, 2010, In: American Journal of Human Genetics. 86, 6, p. 839-49 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Recombinant Adeno-Associated Virus-Mediated microRNA Delivery into the Postnatal Mouse Brain Reveals a Role for miR-134 in Dendritogenesis in Vivo

      Christensen, M., Larsen, Lars Allan, Kauppinen, S. & Schratt, G., 2010, In: Frontiers in Neural Circuits. 3, p. 16

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. 2009
    54. Published

      Characterization of a t(5;8)(q31;q21) translocation in a patient with mental retardation and congenital heart disease: implications for involvement of RUNX1T1 in human brain and heart development

      Zhang, L., Tümer, Asuman Zeynep, Møllgård, Kjeld, Barbi, G., Rossier, E., Bendsen, E., Møller, R. S., Ullmann, R., He, J., Papadopoulos, N., Tommerup, Niels & Larsen, Lars Allan, 2009, In: European Journal of Human Genetics.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Expression analyses of human cleft palate tissue suggest a role for osteopontin and immune related factors in palatal development

      Jakobsen, L. P., Borup, R., Vestergaard, J., Larsen, Lars Allan, Lage, K., Maroun, L. L., Kjær, Inger, Niemann, C. U., Andersen, M., Knudsen, M. A., Møllgård, Kjeld & Tommerup, Niels, 2009, In: Experimental & Molecular Medicine. 41, 2, p. 77-85 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Genome-wide gene expression profiling of SCID mice with T-cell-mediated Colitis

      Brudzewsky, D., Pedersen, Anders Elm, Claesson, Mogens Helweg, Gad, M., Kristensen, N. N., Lage, K., Jensen, T., Tommerup, Niels, Larsen, Lars Allan, Knudsen, S. & Tümer, Asuman Zeynep, 2009, In: Scandinavian Journal of Immunology. 69, 5, p. 437-46 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Molecular characterization of two patients with de novo interstitial deletions in 4q22-q24

      Hilhorst-Hofstee, Y., Tümer, Asuman Zeynep, Born, P., Knijnenburg, J., Hansson, K., Yatawara, V., Steensberg, J., Ullmann, R., Arkesteijn, G., Tommerup, Niels & Larsen, Lars Allan, 2009, In: American Journal of Medical Genetics. Part A. 149A, 8, p. 1830-3 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Published

      The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation

      Clement, C. A., Kristensen, S. G., Møllgård, Kjeld, Pazour, G. J., Yoder, B. K., Larsen, Lars Allan & Christensen, Søren Tvorup, 2009, In: Journal of Cell Science. 122, Pt 17, p. 3070-82 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Using Nucleofection of siRNA Constructs for Knockdown of Primary Cilia in P19.CL6 Cancer Stem Cell Differentiation into Cardiomyocytes

      Clement, C. A., Larsen, Lars Allan & Christensen, Søren Tvorup, 2009, Methods in Cell Biology. Sloboda, R. D. (ed.). Academic Press, Vol. 94. p. 181-197

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    60. 2008
    61. Published

      Diagnostic yield, interpretation, and clinical utility of mutation screening of sarcomere encoding genes in Danish hypertrophic cardiomyopathy patients and relatives

      Andersen, P. S., Havndrup, O., Hougs, L., Sørensen, K. M., Jensen, M., Larsen, Lars Allan, Hedley, P., Bie Thomsen, A. R., Moolman-Smook, J., Christiansen, M. & Bundgård, Henning, 2008, In: Human Mutation. 30, 3, p. 363-370 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Fine mapping of a de novo interstitial 10q22-q23 duplication in a patient with congenital heart disease and microcephaly

      Erdogan, F., Belloso, J. M., Gabau, E., Ajbro, K. D., Guitart, M., Ropers, H. H., Tommerup, Niels, Ullmann, R., Tümer, Asuman Zeynep & Larsen, Lars Allan, 2008, In: European Journal of Medical Genetics. 51, 1, p. 81-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      GLI1 is involved in cell cycle regulation and proliferation of NT2 embryonal carcinoma stem cells

      Vestergaard, J., Lind-Thomsen, A., Pedersen, M. W., Jarmer, H. O., Bak, M., Hasholt, Lis Frydenreich, Tommerup, Niels, Tümer, Asuman Zeynep & Larsen, Lars Allan, 2008, In: DNA and Cell Biology. 27, 5, p. 251-U16

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. Published

      High frequency of submicroscopic genomic aberrations detected by tiling path array comparative genome hybridisation in patients with isolated congenital heart disease

      Erdogan, F., Larsen, Lars Allan, Zhang, L., Tümer, Asuman Zeynep, Tommerup, Niels, Chen, W., Jacobsen, J. R., Schubert, M., Jurkatis, J., Tzschach, A., Ropers, H. & Ullmann, R., 2008, In: Journal of Medical Genetics. 45, 11, p. 704-709 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. Published

      Mapping of 5q35 chromosomal rearrangements within a genomically unstable region

      Buysse, K., Crepel, A., Menten, B., Pattyn, F., Antonacci, F., Veltman, J. A., Larsen, Lars Allan, Tümer, Asuman Zeynep, de Klein, A., van de Laar, I., Devriendt, K., Mortier, G. & Speleman, F., 2008, In: Journal of Medical Genetics. 45, 10, p. 672-678 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. Published

      Multiplex Ligation-Dependent Probe Amplification Technique for Copy Number Analysis on Small Amounts of DNA Material

      Sørensen, K., Andersen, P., Larsen, Lars Allan, Schwartz, M., Schouten, J. & Nygren, A., 2008, In: Analytical Chemistry. 80, p. 9363-9368 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    67. 2007
    68. Published

      A homogeneous assay for analysis of FMR1 promoter methylation in patients with fragile X syndrome

      Dahl, C., Grønskov, K., Larsen, Lars Allan, Guldberg, P. & Brøndum-Nielsen, K., 2007, In: Clinical Chemistry. 53, 4, p. 790-793 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. Published

      Mutations in the Kv1.5 channel gene KCNA5 in cardiac arrest patients.

      Nielsen, N. H., Winkel, B. G., Kanters, Jørgen K., Schmitt, Nicole, Hofman-Bang, J., Jensen, H. S., Bentzen, Bo Hjorth, Sigurd, B., Larsen, Lars Allan, Andersen, P. S., Kjeldsen, K., Grunnet, Morten, Christiansen, M., Olesen, Søren-Peter & Haunsø, Stig, 2007, In: Biochemical and Biophysical Research Communications. 354, 3, p. 776-82 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      Pierre Robin sequence may be caused by dysregulation of SOX9 and KCNJ2

      Jakobsen, L. P., Ullmann, R., Christensen, S. B., Jensen, K. E., Molsted, K., Henriksen, K. F., Hansen, C., Knudsen, M. A. F., Larsen, Lars Allan, Tommerup, Niels & Tümer, Asuman Zeynep, 2007, In: Journal of Medical Genetics. 44, 6, p. 381-386 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Published

      Single-strand conformation polymorphism analysis using capillary array electrophoresis for large-scale mutation detection

      Larsen, Lars Allan, Jespersgaard, C. & Andersen, P. S., 2007, In: Nature Protocols (Print Edition). 2, 6, p. 1458-1466 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. Published

      YKL-40 protein expression in the early developing human musculoskeletal system

      Johansen, J. S., Høyer, P. E., Larsen, Lars Allan, Price, P. A. & Møllgård, Kjeld, 2007, In: Journal of Histochemistry & Cytochemistry. 55, 12, p. 1213-1228 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    73. 2006
    74. Published

      Delineation of a 2.2 Mb microdeletion at 5q35 associated with microcephaly and congenital heart disease

      Baekvad-Hansen, M., Tümer, Asuman Zeynep, Delicado, A., Erdogan, F., Tommerup, Niels & Larsen, Lars Allan, 2006, In: American Journal of Medical Genetics. Part A. 140A, 5, p. 427-433 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. Published

      Evaluation of two methods for generating cRNA for microarray experiments from nanogram amounts of total RNA.

      Bak, M., Conley, L., Hedegaard, J., Larsen, Lars Allan, Sørensen, P., Bendixen, C. & Tommerup, Niels, 2006, In: Analytical Biochemistry. 358, 1, p. 111-9 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    76. Published

      Hedgehog signaling in small-cell lung cancer: Frequent in vivo but a rare event in vitro

      Vestergaard, J., Pedersen, M. W., Pedersen, N., Ensinger, C., Tümer, Asuman Zeynep, Tommerup, Niels, Poulsen, H. S. & Larsen, Lars Allan, 2006, In: Lung Cancer. 52, 3, p. 281-290 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Published

      Optimization of capillary array electrophoresis single-strand conformation polymorphism analysis for routine molecular diagnostics

      Jespersgaard, C., Larsen, Lars Allan, Baba, S., Kukita, Y., Tahira, T., Christiansen, M., Vuust, J., Hayashi, K. & Andersen, P. S., 2006, In: Electrophoresis. 27, 19, p. 3816-3822 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      Screening for fragilt X-syndrom. Internationale erfaringer

      Vuust, J., Larsen, Lars Allan, Gronskov, K., Norgaard-Pedersen, B. & Brondum-Nielsen, K., 2006, In: Ugeskrift for læger. 168, 43, p. 3704-3709 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      Screening of 99 Danish patients with congenital heart disease for GATA4 mutations

      Zhang, L., Tümer, Asuman Zeynep, Jacobsen, J. R., Andersen, P. S., Tommerup, Niels & Larsen, Lars Allan, 2006, In: Genetic Testing. 10, 4, p. 277-80 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. 2005
    81. Published

      Delineation of an interstitial 9q22 deletion in basal cell nevus syndrome

      Boonen, S. E., Stahl, D., Kreiborg, S., Rosenberg, T., Kalscheuer, V., Larsen, Lars Allan, Tommerup, Niels & Brøndum-Nielsen, K., 2005, In: American Journal of Medical Genetics. Part A. Vol. 132, p. 324-328

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. Published

      High Throughput Single-Strand Conformation Polymorphism Analysis on a Microfabricated Capillary Array Electrophoresis Dervice

      Tian, H., Emrich, C. A., Scherer, J., Mathies, R. A., Andersen, P. S., Larsen, Lars Allan & Christiansen, M., 2005, In: Electrophoresis. Vol. 26, p. 1834-1842

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Published

      Mutations in the HERG ion channel: A novel link between long QT syndrome and sudden death syndrome

      Christiansen, M., Tønder, N., Larsen, Lars Allan, Andersen, P. S., Simonsen, H. B., Øyen, N., Kanters, J. K., Jacobsen, J. R., Fosdal, I., Wettrell, G. & Kjeldsen, K., 2005, In: American Journal of Cardiology. Vol. 95, p. 433-434

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. Published

      Mutations in the genes KCND2 and KCND3 encoding the ion-channels Kv 4.2. and Kv 4.3, conducting the cardiac fast transient outward current ( ITo,f), are not a frequent cause of Long QT syndrome

      Frank-Hansen, R., Larsen, Lars Allan, Andersen, P. S., Jespersgård, C. & Christiansen, M., 2005, In: Clinica Chimica Acta. Vol. 351, p. 95-100

      Research output: Contribution to journal › Journal article › Research › peer-review

    85. Published

      One third of Danish hypertrophic cardiomyopathy patients with MYH7 mutations have mutations [corrected] in MYH7 rod region

      Hougs, L., Havndrup, O., Bundgård, Henning, Køber, Lars Valeur, Vuust, J., Larsen, Lars Allan, Christiansen, M. & Andersen, P. S., 2005, In: European Journal of Human Genetics. 13, 2, p. 161-5 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. Published

      One-third of Danish hyperytrophic cardiomyopathy patients with MYH7 mutations have mutations in rod region

      Hougs, L., Havndrup, O., Bundgaard, H., Køber, L., Vuust, J., Larsen, Lars Allan, Christiansen, M. & Andersen, P. S., 2005, In: European Journal of Human Genetics. Vol. 13, p. 161-165

      Research output: Contribution to journal › Journal article › Research › peer-review

    87. Published

      Potassium Must Be Considered in Congenital Long QT Syndrome

      Christiansen, M., Kjeldsen, K., Wettrell, G., Larsen, Lars Allan, Lundkvist, L., Andersen, P. S., Tran, C. T., Kanters, J. K. & Vuust, J., 2005, In: Cardiology. Vol. 5, p. 54-58

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      The eponymous Jacobsen syndrome: mapping the breakpoints of the original family suggests an association between the distal 1.1. Mb of chromosome 21 and osteoporosis in Down syndrome

      Tümer, Asuman Zeynep, Henriksen, A. M., Bache, Iben, Larsen, Lars Allan, Brixen, K., Illum, N., Rasmussen, K. & Tommerup, Niels, 2005, In: American Journal of Medical Genetics. Part C: Seminars in Medical Genetics. Vol. 135A, p. 339-341

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. 2004
    90. Published

      Delineation of an interstitial 9q22 deletion in basal cell nevus syndrome

      Boonen, S. E., Stahl, D., Kreiborg, Sven, Rosenberg, T., Kalscheuer, V., Larsen, Lars Allan, Tommerup, Niels, Brøndum-Nielsen, K. & Tümer, Asuman Zeynep, 2004, In: American Journal of Medical Genetics. Part C: Seminars in Medical Genetics. Vol. 132A, p. 324-328

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. Published

      Does KCNE5 play a role in long QT syndrome?

      Hofman-Bang, J., Jespersen, Thomas, Grunnet, Morten, Larsen, Lars Allan, Andersen, P. S., Kanters, Jørgen K., Kjeldsen, K. & Christiansen, M., 2004, In: Clinica Chimica Acta. 345, 1-2, p. 49-53 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      GJB2 and GJB6 mutations in 165 Danish patients showing non-syndromic hearing impairment

      Grønskov, K., Larsen, Lars Allan, Rendtorff, N. D., Parving, A., Nørgaard-Pedersen, B. & Brøndum-Nielsen, K., 2004, In: Genet Test. Vol. 8, p. 181-184

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. Published

      Genetic and phenotypic characterization of mutations in myosin-binding protein C (MYBPC3) in 81 families with familial hypertrophic cardiomyopathy: total or partial haploinsufficiency

      Andersen, P. S., Havndrup, O., Bundgaard, H., Larsen, Lars Allan, Vuust, J., Pedersen, A. K., Kjeldsen, K. & Christiansen, M., 2004, In: European Journal of Human Genetics. Vol. 12, p. 673-677

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      High Throughput Mutation Screening

      Andersen, P. S. & Larsen, Lars Allan, 2004, Molecular Analysis and Genome Discovery. New York: IEEE Computer Society Press, p. chap. 5

      Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research

    95. Published

      Identification of a novel EYA1 splice-site mutation in a Danish branchio-oto-renal syndrome family

      Henriksen, A. M., Tümer, Asuman Zeynep, Tommerup, Niels, Tranebjærg, Lisbeth & Larsen, Lars Allan, 2004, In: Genetic Testing. 8, 4, p. 404-6 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    96. Published

      T wave morphology analysis distinguishes between KvLQT1 and HERG mutations in long QT syndrome

      Kanters, J. K., Fanoe, S., Larsen, Lars Allan, Bloch-Thomsen, P. E., Toft, E. & Christansen, M., 2004, In: Heart Rhythm. Vol. 1, p. 285-292

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. 2003
    98. Published

      Capillary electrophoresis-based single stand dna conformation analysis in high-throughput mutation screening

      Andersen, P. S., Jespersgaard, C., Vuust, J., Christiansen, M. & Larsen, Lars Allan, 2003, In: Human Mutation. Vol. 21, p. 455-65

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Published

      High-througput single strand conformation polymorphism mutation detection by automated capillary array electrophoresis: validation of the method

      Andersen, P. S., Jespersgaard, C., Vuust, J., Christiansen, M. & Larsen, Lars Allan, 2003, In: Human Mutation. Vol. 21, p. 116-122

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Published

      Outcome of clinical versus genetic family screening in hypertrophic cardiomyopathy with focus on cardiac beta-myosin gene mutations

      Havndrup, O., Bundgaard, H., Andersen, P. S., Larsen, Lars Allan, Vuust, J., Kjeldsen, K. & Christiansen, M., 2003, In: Cardiovascular Research. Vol. 57, p. 298-301

      Research output: Contribution to journal › Journal article › Research › peer-review

    101. Published

      The Hedgehog signaling pathway - implications for drug targets in cancer and neurodegenerative disorders

      Bak, M., Hansen, C., Tommerup, Niels & Larsen, Lars Allan, 2003, In: Pharmacogenomics. Vol. 4, p. 411-429

      Research output: Contribution to journal › Journal article › Research › peer-review

    102. 2001
    103. Published

      Screening for mutations and polymorphisms in the genes KCNH2 and KCNE2 encoding the cardiac HERG/MiRPI ion channel: Implications for acquired and congenital long Q-T syndrome

      Larsen, Lars Allan, Andersen, P. S., Kanters, Jørgen K., Svendsen, I. H., Jacobsen, J. R., Vuust, J., Wettrell, G., Tranebjærg, Lisbeth, Bathen, J. & Christiansen, M., 6 Aug 2001, In: Clinical Chemistry. 47, 8, p. 1390-1395 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    104. Published

      Screening for mutations and polymorphisms in the genes KCNH2 and KCNE2 encoding the cardiac HERG/MiRP1 ion channel: Implications for acquired and congenital long QT syndrome

      Larsen, Lars Allan, Andersen, P. S., Kanters, Jørgen K., Svendsen, I. H., Jacobsen, J. R., Vuust, J., Wetrell, G., Tranebjærg, Lisbeth & Christiansen, M., 2001, In: Clinical Chemistry. 47, 8, p. 1390-1395

      Research output: Contribution to journal › Journal article › Research › peer-review

    105. 1998
    106. Published

      Novel donor splice site mutation in the KVLQT1 gene is associated with long QT syndrome

      Kanters, Jørgen K., Larsen, Lars Allan, Orholm, M., Agner, E., Andersen, P. S., Vuust, J. & Christiansen, M., 1 Jan 1998, In: Journal of Cardiovascular Electrophysiology. 9, 6, p. 620-624 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    107. 1997
    108. Published

      High-throughput analysis of Fragile X (CGG)n alleles in the normal and premutation range by PCR amplification and automated capillary electrophoresis

      Larsen, Lars Allan, Grønskov, K., Nørgaard-Pedersen, B., Brøndum-Nielsen, K., Hasholt, Lis Frydenreich & Vuunst, J., 1997, In: Human Genetics. 100, p. 564-568

      Research output: Contribution to journal › Journal article › Research › peer-review

    ID: 2949