Kristoffer Lihme Egerod
Research consultant
Pers Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal, 2200 København N.
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MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans
Andersson, E. A., Holst, Birgitte, Sparsø, T., Grarup, Niels, Banasik, Karina, Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Egerod, Kristoffer Lihme, Lauritzen, T., Sørensen, Thorkild I.A., Bonnefond, A., Meyre, D., Froguel, P., Schwartz, Thue W., Pedersen, Oluf Borbye & Hansen, Torben, 2010, In: Diabetes. 59, 6, p. 1539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial fermentation of flaxseed fibers modulates the transcriptome of GPR41-expressing enteroendocrine cells and protects mice against diet-induced obesity
Arora, Tulika, Rudenko, Olga, Egerod, Kristoffer Lihme, Husted, Anna Sofie, Kovatcheva-Datchary, P., Akrami, R., Kristensen, M., Schwartz, Thue W. & Backhed, F., Mar 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 3, p. E453-E463Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission
Bentsen, M. A., Rausch, D. M., Mirzadeh, Z., Muta, K., Scarlett, J. M., Brown, J. M., Herranz-Pérez, V., Baquero, A. F., Thompson, J., Alonge, K. M., Faber, C. L., Kaiyala, K. J., Bennett, C., Pyke, C., Ratner, C., Egerod, K. L., Holst, B., Meek, T. H., Kutlu, B., Zhang, Y. & 9 others, , 2020, In: Nature Communications. 11, 1, 4458.Research output: Contribution to journal › Journal article › Research › peer-review
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A novel dopamine transporter transgenic mouse line for identification and purification of midbrain dopaminergic neurons reveals midbrain heterogeneity
Apuschkin, Mia, Stilling, S., Rahbek-Clemmensen, T., Sørensen, G., Fortin, G., Herborg, Freja, Eriksen, J., Trudeau, L., Egerod, Kristoffer Lihme, Gether, Ulrik & Rickhag, Karl Mattias, 2015, In: European Journal of Neuroscience. 42, 7, p. 2438-2454 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration
Cornelia Peeters, M., Fokkelman, M., Boogaard, B., Egerod, Kristoffer Lihme, van de Water, B., IJzerman, A. P. & Schwartz, Thue W., Dec 2015, In: Cellular Signalling. 27, 12, p. 2579-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular cloning and functional expression of the first two specific insect myosuppressin receptors.
Egerod, Kristoffer Lihme, Reynisson, E., Hauser, Frank, Cazzamali, G., Williamson, M. & Grimmelikhuijzen, Cornelis (Cok), 2003, In: Proceedings of the National Academy of Science of the United States of America. 100, 17, p. 9808-13 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular identification of the first insect proctolin receptor.
Egerod, Kristoffer Lihme, Reynisson, E., Hauser, Frank, Williamson, M., Cazzamali, G. & Grimmelikhuijzen, Cornelis (Cok), 2003, In: Biochemical and Biophysical Research Communications. 306, 2, p. 437-42 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue.
Egerod, Kristoffer Lihme, Holst, Birgitte, Petersen, P. S., Hansen, Jacob B., Mulder, J., Hökfelt, T. & Schwartz, Thue W., 2007, In: Molecular Endocrinology. 21, 7, p. 1685-98 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells
Egerod, Kristoffer Lihme, Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Zhao, M., Barir-Jensen, D., Nygaard, E. B., Petersen, N., Holst, Jens Juul & Schwartz, Thue W., Nov 2015, In: Endocrinology. 156, 11, p. 3909-23 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin
Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, Kaare Villum, Nøhr, M. K., Secher, A., Sakata, I., Pedersen, Jens, Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In: Endocrinology. 153, 12, p. 5782-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms
Egerod, Kristoffer Lihme, Petersen, N., Timshel, P. N., Rekling, Jens Christian, Wang, Y., Liu, Q., Schwartz, Thue W. & Gautron, L., 2018, In: Molecular Metabolism. 12, p. 62-75 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Molecular Diversity of Vagal Afferents Revealed
Egerod, Kristoffer Lihme, Schwartz, Thue W. & Gautron, L., 2019, In: Trends in Neurosciences. 42, 10, p. 663-666Research output: Contribution to journal › Editorial › Research › peer-review
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A Potential Role for GPR39 in Protection and Differentiation of Metabolic and Endocrine Tissues.
Egerod, Kristoffer Lihme, 2008, Museum Tusculanum.Research output: Book/Report › Ph.D. thesis › Research
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ß-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced Hyperglycemia
Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Wierup, N., Sundler, F., Holst, Birgitte & Schwartz, Thue W., 2011, In: International Journal of Endocrinology. 2011, p. 401258Research output: Contribution to journal › Journal article › Research › peer-review
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GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)
Ekberg, J. H., Pedersen, M. H., Kristensen, L. V., Madsen, A. N., Engelstoft, M. S., Husted, Anna Sofie, Sichlau, R., Egerod, Kristoffer Lihme, Timshel, P., Kowalski, T. J., Gribble, F. M., Reiman, F., Hansen, Harald S., Howard, A. D., Holst, Birgitte & Schwartz, Thue W., 25 Oct 2016, In: Endocrinology. 157, 12, p. 4561-4569 9 p., en20161334.Research output: Contribution to journal › Journal article › Research › peer-review
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Research Resource: A Chromogranin A Reporter for Serotonin and Histamine Secreting Enteroendocrine Cells
Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Egerod, Kristoffer Lihme, Osborne-Lawrence, S., Poulsen, Steen Seier, Zigman, J. M. & Schwartz, Thue W., Nov 2015, In: Molecular endocrinology (Baltimore, Md.). 29, 11, p. 1658-71 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enteroendocrine cell types revisited
Engelstoft, M. S., Egerod, Kristoffer Lihme, Lund, M. L. & Schwartz, Thue W., Dec 2013, In: Current Opinion in Pharmacology. 13, 6, p. 912-21 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells
Engelstoft, M. S., Park, W-M., Sakata, I., Kristensen, L. V., Husted, A. S., Osborne-Lawrence, S., Piper, P. K., Walker, A. K., Pedersen, M. H., Nøhr, M. K., Pan, J., Sinz, C. J., Carrington, P. E., Akiyama, T. E., Jones, R. M., Tang, C., Ahmed, K., Offermanns, S., Egerod, K. L., Zigman, J. M. & 1 others, , Nov 2013, In: Molecular Metabolism. 2, 4, p. 376-92 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A gut feeling for obesity: 7TM sensors on enteroendocrine cells
Engelstoft, M. S., Egerod, Kristoffer Lihme, Holst, Birgitte & Schwartz, Thue W., 2008, In: Cell Metabolism. 8, 6, p. 447-9 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions.
Frimurer, Thomas Michael, Mende, F., Graae, A., Engelstoft, M. S., Egerod, Kristoffer Lihme, Nygaard, R., Gerlach, L., Hansen, J. B., Schwartz, Thue W. & Holst, Birgitte, 2017, In: Journal of Medicinal Chemistry. 60, 3, p. 886-898 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neurotensin Is Co-Expressed, Co-Released And Acts Together With Glp-1 And Pyy In Enteroendocrine Control Of Metabolism
Grunddal, Kaare Villum, Ratner, C. F., Svendsen, B., Sommer, F., Engelstoft, M. S., Madsen, A. N., Pedersen, Jens, Nøhr, M. K., Egerod, Kristoffer Lihme, Nawrocki, A. R., Kowalski, T., Howard, A. D., Poulsen, Steen Seier, Offermanns, S., Bäckhed, G. F., Holst, Jens Juul, Holst, Birgitte & Schwartz, Thue W., Jan 2016, In: Endocrinology. 157, 1, p. 176-94 19 p., en20151600.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmin-driven fibrinolysis facilitates skin tumor growth in a gender-dependent manner
Hald, A., Eickhardt, H., Maerkedahl, R. B., Feldborg, C. W., Egerod, Kristoffer Lihme, Engelholm, Lars Henning, Laerum, O. D., Lund, L. R. & Rønø, B., Nov 2012, In: F A S E B Journal. 26, 11, p. 4445-4457 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential effects of repeated low dose treatment with the cannabinoid agonist WIN 55,212-2 in experimental models of bone cancer pain and neuropathic pain
Hald, A., Ding, M., Egerod, Kristoffer Lihme, Hansen, R. R., Konradsen, D., Jørgensen, S. G., Atalay, B., Nasser, A., Bjerrum, Ole Jannik & Heegaard, Anne-Marie, 2008, In: Pharmacology, Biochemistry and Behavior. 91, 1, p. 38-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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LPS counter regulates RNA expression of extracellular proteases and their inhibitors in murine macrophages
Hald, A., Rønø, B., Lund, L. R. & Egerod, Kristoffer Lihme, 2012, In: Mediators of Inflammation. 2012, 157894, p. 157894 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GPR39 signaling is stimulated by zinc ions but not by obestatin
Holst, Birgitte, Egerod, Kristoffer Lihme, Schild, E., Vickers, S. P., Cheetham, S., Gerlach, L., Storjohann, L., Stidsen, C. E., Jones, R., Beck-Sickinger, A. G. & Schwartz, Thue W., 2006, In: Endocrinology. 148, 1, p. 13-20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3417
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L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
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Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms
Research output: Contribution to journal › Journal article › Research › peer-review
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