Kristian Strømgaard

Kristian Strømgaard

Professor


  1. 2020
  2. Published

    Mechanism and site of action of big dynorphin on ASIC1a

    Borg, C. B., Braun, N., Heusser, Stephanie, Bay, Y., Weis, D., Galleano, I., Lund, Camilla, Tian, W., Haugaard-Kedström, L. M., Bennett, Eric Paul, Lynagh, T., Strømgaard, Kristian, Andersen, J. & Pless, Stephan, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 13, p. 7447-7454

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain

    Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, G., Jensen, K. L., Rathje, M., Jensen, D. B., Erlendsson, S., Bartling, C. R. O., Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, K., Arleth, L., Sørensen, A. T., Bach, A. & 5 others, Strømgaard, Kristian, Meehan, Claire Francesca, Vægter, C. B., Gether, Ulrik & Madsen, Kenneth Lindegaard, 2020, In: EMBO Molecular Medicine. 12, 6, 25 p., e11248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The Effects of Lipidation on a TAT-Containing Peptide-Based Inhibitor of PSD-95

    Alves Fernandes, Eduardo Felipe, Haugaard-Kedstroem, L. M. & Strømgaard, Kristian, 2020, In: Australian Journal of Chemistry. 73, 4, p. 307-311 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation

    Kristensen, Mie, Kucharz, Krzysztof, Alves Fernandes, Eduardo Felipe, Strømgaard, Kristian, Schallburg Nielsen, M., Cederberg Helms, H. C., Bach, Anders, Ulrikkaholm Tofte-Hansen, M., Aldana, Blanca, Lauritzen, Martin & Larsen, Birger Brodin, 2020, In: Pharmaceutics. 12, 7, 24 p., 661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A Novel Glycine Receptor Variant with Startle Disease Affects Syndapin I and Glycinergic Inhibition

    Langlhofer, G., Schaefer, N., Maric, H. M., Keramidas, A., Zhang, Y., Baumann, P., Blum, R., Breitinger, U., Strømgaard, Kristian, Schlosser, A., Kessels, M. M., Koch, D., Qualmann, B., Breitinger, H. G., Lynch, J. W. & Villmann, C., 2020, In: Journal of Neuroscience. 40, 25, p. 4954-4969 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Heterotrimeric G Proteins as Therapeutic Targets in Drug Discovery

    Li, J., Ge, Y., Huang, J., Strømgaard, Kristian, Zhang, X. & Xiong, X., 2020, In: Journal of Medicinal Chemistry. 63, 10, p. 5013-5030 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Site-Specific Phosphorylation of PDZ Domains

    Ma, S., Strømgaard, Kristian & Clemmensen, L. S., 2020, Expressed Protein Ligation: Methods and Protocols. M. V-P. (ed.). Humana Press, p. 235-261 27 p. (Methods in molecular biology (Clifton, N.J.), Vol. 2133).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  9. Published

    Targeting receptor complexes: a new dimension in drug discovery

    Rosenbaum, M. I., Clemmensen, L. S., Bredt, D. S., Bettler, B. & Strømgaard, Kristian, 2020, In: Nature Reviews. Drug Discovery. 19, p. 884-901 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Comparing the binding properties of peptides mimicking the Envelope protein of SARS-CoV and SARS-CoV-2 to the PDZ domain of the tight junction-associated PALS1 protein

    Toto, A., Ma, S., Malagrinò, F., Visconti, L., Pagano, L., Strømgaard, Kristian & Gianni, S., 2020, In: Protein Science. 29, 10, p. 2038-2042 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Recent achievements in developing selective Gq inhibitors

    Zhang, H., Nielsen, A. L. & Strømgaard, Kristian, 2020, In: Medicinal Research Reviews. 40, 1, p. 135-157

    Research output: Contribution to journalReviewResearchpeer-review

  12. 2019
  13. Published

    Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor

    Bach, Anders, Clausen, B. H., Kristensen, L. K., Andersen, M. G., Ellman, D. G., Hansen, P. B. L., Hasseldam, Henrik, Heitz, M., Özcelik, D., Tuck, E. J., Kopanitsa, M. V., Grant, S. G. N., Lykke-Hartmann, K., Johansen, F. F., Lambertsen, K. L. & Strømgaard, Kristian, May 2019, In: Neuropharmacology. 150, p. 100-111 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    PDZ Domains as Drug Targets

    Christensen, N. R., Čalyševa, J., Alves Fernandes, Eduardo Felipe, Lüchow, S., Clemmensen, L. S., Haugaard-Kedström, L. M. & Strømgaard, Kristian, 2019, In: Advanced Therapeutics. 2, 7, p. 1800143 1800143.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity

    Malfacini, D., Patt, J., Annala, S., Harpsøe, Kasper, Eryilmaz, F., Reher, R., Crüsemann, M., Hanke, W., Zhang, H., Tietze, D., Gloriam, David E., Bräuner, Hans, Strømgaard, Kristian, König, G. M., Inoue, A., Gomeza, J. & Kostenis, E., 12 Apr 2019, In: The Journal of Biological Chemistry. 294, 15, p. 5747-5758

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Plant polyphenols inhibit functional amyloid and biofilm formation in Pseudomonas strains by directing monomers to off-pathway oligomers

    Najarzadeh, Z., Mohammad-Beigi, H., Pedersen, J. N., Christiansen, G., Sønderby, T. V., Shojaosadati, S. A., Morshedi, D., Strømgaard, Kristian, Meisl, G., Sutherland, D., Pedersen, J. S. & Otzen, D. E., 2019, In: Biomolecules. 9, 11, 21 p., 659.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Designing Poly-agonists for Treatment of Metabolic Diseases: Challenges and Opportunities

    Petersen, Jonas Odgaard, Strømgaard, Kristian, Frølund, Bente & Clemmensen, Christoffer, 2019, In: Drugs. 79, 11, p. 1187-1197 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Targeting the gamma-Aminobutyric Acid Type B (GABA(B)) Receptor Complex: Development of Inhibitors Targeting the K+ Channel Tetramerization Domain (KCTD) Containing Proteins/GABA(B) Receptor Protein-Protein Interaction

    Sereikaité, Vita, Fritzius, T., Kasaragod, V. B., Bader, N., Maric, H. M., Schindelin, H., Bettler, B. & Strømgaard, Kristian, 2019, In: Journal of Medicinal Chemistry. 62, 19, p. 8819-8830

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Structure–Activity Relationship Studies of the Natural Product G q/11 Protein Inhibitor YM-254890

    Xiong, X. F., Zhang, H., Boesgaard, M. W., Underwood, C. R., Bräuner, Hans & Strømgaard, Kristian, Apr 2019, In: ChemMedChem. 14, 8, p. 865-870

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2018
  21. Published

    Protein Engineering Reveals Mechanisms of Functional Amyloid Formation in Pseudomonas aeruginosa Biofilms

    Bleem, A., Christiansen, G., Madsen, D. J., Maric, H., Strømgaard, Kristian, Bryers, J. D., Daggett, V., Meyer, R. L. & Otzen, D. E., 2018, In: Journal of Molecular Biology. 430, 20, p. 3751-3763 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Peptide Modulation of Acid-Sensing Ion Channels

    Borg, C. B., Haugaard-Kedstrom, L. M., Lynagh, T., Strømgaard, Kristian & Pless, Stephan, 2 Feb 2018, p. 130A-130A.

    Research output: Contribution to conferencePosterResearch

  23. Published

    Prevention of glutamate-induced retinal ganglion cell death by UCCB01-144 treatment

    Bulli, G., Vohra, Rupali, Skytt, D. M., Strømgaard, Kristian & Kolko, Miriam, 2018, In: Acta Ophthalmologica. 96, S261, p. 17-17 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  24. Published

    Probing the Mint2 Protein-Protein Interaction Network Relevant to the Pathophysiology of Alzheimer's Disease

    Jensen, T. M. T., Albertsen, L., Bartling, Christian Reinhard Otto, Haugaard-kedström, L. M. & Strømgaard, Kristian, 2018, In: ChemBioChem. 19, 11, p. 1119-1122 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Controlling Ca2+ Permeable alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Photochromic Ion Channel Blockers

    Norager, N. G., Poulsen, Mette Homann & Strømgaard, Kristian, 13 Sep 2018, In: Journal of Medicinal Chemistry. 61, 17, p. 8048-8053

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Probing Backbone Hydrogen Bonds in Proteins by Amide-to-Ester Mutations

    Sereikaité, Vita, Jensen, T. M. T., Bartling, Christian Reinhard Otto, Jemth, P., Pless, Stephan & Strømgaard, Kristian, 18 Oct 2018, In: ChemBioChem. 19, 20, p. 2136-2145

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    Structure–activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359

    Zhang, H., Nielsen, A. L., Boesgaard, M. W., Harpsøe, Kasper, Daly, N. L., Xiong, X., Underwood, C. R., Haugaard-kedström, L. M., Bräuner, Hans, Gloriam, David E. & Strømgaard, Kristian, 2018, In: European Journal of Medicinal Chemistry. 156, p. 847-860

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2017
  29. Published

    Stoichiometry of Toxin Binding to Acid-Sensing Ion Channels

    Borg, C. B., Lynagh, T., Haugaard-Kedstrom, L. M., Strømgaard, Kristian & Pless, Stephan, 3 Feb 2017, In: Biophysical Society. Annual Meeting. Abstracts. 112, 3, p. 420A-420A

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

ID: 1302559