Hans Bräuner
Prodekan for forskning
Faculty Service
Blegdamsvej 3
2200 København N.
- 2017
- Published
Detailed characterization of the in vitro pharmacological and pharmacokinetic properties of N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine (25CN-NBOH), a highly selective and brain-penetrant 5-HT2A receptor agonist
Jensen, Anders A., McCorvy, J. D., Petersen, S. L., Bundgaard, C., Liebscher, G., Kenakin, T. P., Bräuner, Hans, Kehler, J. & Kristensen, Jesper Langgaard, 2017, In: Journal of Pharmacology and Experimental Therapeutics. 361, 3, p. 441-453Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function
Jorgensen, S., Have, C. T., Underwood, C. R., Johansen, L. D., Wellendorph, Petrine, Gjesing, A. P., Jorgensen, C. V., Quan, S., Rui, G., Inoue, A., Linneberg, Allan René, Grarup, Niels, Jun, W., Pedersen, Oluf Borbye, Hansen, Torben & Bräuner, Hans, 2017, In: The Journal of Biological Chemistry. 292, 4, p. 1524-1534 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer
Jacobsen, S. E., Gether, Ulrik & Bräuner, Hans, 2017, In: Scientific Reports. 7, 14 p., 46355.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Robust GLP-1 secretion by basic L-amino acids does not require the GPRC6A receptor
Clemmensen, Christoffer, Jørgensen, C. V., Smajilovic, S. & Bräuner, Hans, 2017, In: Diabetes, Obesity and Metabolism. 19, 4, p. 599-603Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural insight to mutation effects uncover a common allosteric site in class C GPCRs
Harpsøe, Kasper, Boesgaard, M. W., Munk, C., Bräuner, Hans & Gloriam, David E., 2017, In: Bioinformatics (Oxford, England). 33, 8, p. 1116-1120 5 p., btw784.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GPRC6A Receptor displays Constitutive Internalization and Sorting to the Slow Recycling Pathway
Jacobsen, S. E., Ammendrup-Johnsen, I., Jansen, A. M., Gether, Ulrik, Madsen, Kenneth Lindegaard & Bräuner, Hans, 2017, In: The Journal of Biological Chemistry. 292, 17, p. 6910-6926Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The orphan G protein-coupled receptor GPR139 is activated by the peptides: Adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and the conserved core motif HFRW
Jensen, A. C. N., Shehata, M. A., Hauser, Alexander Sebastian, Isberg, V., Mokrosinski, J., Farooqi, I. S., Pedersen, D. S., Gloriam, David E. & Bräuner, Hans, 1 Jan 2017, In: Neurochemistry International. 102, p. 105-113Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Knockin mouse with mutant Gα11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors
Roszko, K. L., Bi, R., Gorvin, C. M., Bräuner, Hans, Xiong, X., Inoue, A., Thakker, R. V., Strømgaard, Kristian, Gardella, T. & Mannstadt, M., 9 Feb 2017, In: JCI insight. 2, 3, 15 p., e91079.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site
Shehata, M. A., Jensen, A. C. N., Jespers, W., Floryan, L., Isberg, V., Andersen, K. B., Åqvist, J., Gutiérrez-de-Terán, H., Bräuner, Hans & Gloriam, David E., 25 Apr 2017, In: Scientific Reports. 7, 9 p., 1128.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Relationship Studies of the Cyclic Depsipeptide Natural Product YM-254890, Targeting the Gq Protein
Zhang, H., Xiong, X., Boesgaard, M. W., Underwood, C. R., Bräuner, Hans & Strømgaard, Kristian, 7 Jun 2017, In: ChemMedChem. 12, 11, p. 830-834 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of Histamine H3 Receptor Ligands Using a New Crystal Structure Fragment-based Method
Frandsen, I. O., Boesgaard, M. W., Fidom, K., Hauser, Alexander Sebastian, Isberg, V., Bräuner, Hans, Wellendorph, Petrine & Gloriam, David E., 6 Jul 2017, In: Scientific Reports. 7, 1, 10 p., 4829.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Applying label-free dynamic mass redistribution assay for studying endogenous FPR1 receptor signalling in human neutrophils
Christensen, H. B., Gloriam, David E., Pedersen, D. S., Cowland, J. B., Borregaard, N. & Bräuner, Hans, 15 Jul 2017, In: Journal of Pharmacological and Toxicological Methods. 88, Pt 1, p. 72-78 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of AICP as a GluN2C-Selective N-Methyl-d-Aspartate Receptor Superagonist at the GluN1 Glycine Site
Jessen, M., Frederiksen, K., Yi, F., Clausen, Rasmus Prætorius, Hansen, K. B., Bräuner, Hans, Kilburn, J. P. & Damholt, A., Aug 2017, In: Molecular Pharmacology. 92, 2, p. 151-161 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1)
Jørgensen, L., Al-Khawaja, A., Kickinger, S., Vogensen, S. B., Skovgaard-Petersen, J., Rosenthal, E., Borkar, N., Löffler, R., Madsen, K. K., Bräuner, Hans, Schousboe, Arne, Ecker, G. F., Wellendorph, Petrine & Clausen, Rasmus Prætorius, 9 Oct 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 8834-8846Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Investigating Internalization and Intracellular Trafficking of GPCRs: New Techniques and Real-Time Experimental Approaches
Foster, S. R. & Bräuner, Hans, 11 Oct 2017, Handbook of Experimental Pharmacology. Springer, Vol. 245. p. 41-61 (Handbook of Experimental Pharmacology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview
CGTP Collaborators, C. C., Dec 2017, In: British Journal of Pharmacology. 174, p. S1-S16Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302910
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Kemogenomik: Receptoren set fra lægemiddelstoffets synspunkt
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