Finn Cilius Nielsen
Clinical Professor
- 2024
- Published
Molecular subtyping improves breast cancer diagnosis in the Copenhagen Breast Cancer Genomics Study
Berg, T., Jensen, M. B., Celik, A., Talman, M. L., Misiakou, M. A., Knoop, A. S., Nielsen, Finn Cilius, Ejlertsen, Bent Laursen & Rossing, Caroline Maria, 2024, In: JCI insight. 9, 7, 13 p., e178114.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Multigene profiles to guide the use of neoadjuvant chemotherapy for breast cancer: a Copenhagen Breast Cancer Genomics Study
Jensen, M., Pedersen, C. B., Misiakou, M., Talman, M. L. M., Gibson, L., Tange, U. B., Kledal, H., Vejborg, I., Kroman, Niels Thorndahl, Nielsen, Finn Cilius, Ejlertsen, Bent Laursen & Rossing, M., 2023, In: npj Breast Cancer. 9, 8 p., 47.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neoepitope load, T cell signatures and PD-L2 as combined biomarker strategy for response to checkpoint inhibition immunotherapy
Borch, A., Bjerregaard, A. M., Araujo Barbosa de Lima, V., Østrup, O., Yde, C. W., Eklund, A. C., Mau-Sørensen, M., Barra, C., Svane, Inge Marie, Nielsen, Finn Cilius, Funt, S. A., Lassen, Ulrik Niels & Hadrup, S. R., 2023, In: Frontiers in Genetics. 14, 13 p., 1058605.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New pathogenic germline variants identified in mesothelioma
Belcaid, L., Bertelsen, B., Wadt, Karin Anna Wallentin, Tuxen, I., Spanggaard, I., Højgaard, M., Sørensen, Jens Benn, Ravn, J., Lassen, Ulrik Niels, Nielsen, Finn Cilius, Rohrberg, K. & Westmose Yde, C., 2023, In: Lung Cancer. 179, 8 p., 107172.Research output: Contribution to journal › Review › Research › peer-review
- Published
Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2
AOCS Group, A. G., CZECANCA Consortium, C. C., The Consortium of Investigators of Modifiers of BRCA1/2, T. C. O. I. O. M. O. B., Evidence-based Network for the Interpretation of Germline Mutant Alleles Consortium, E. N. F. T. I. O. G. M. A. C., HEBON Investigators, H. I. & GEMO Study Collaborators, G. S. C., 2023, In: British Journal of Cancer. 128, 12, p. 2283-2294 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Incidence, Survival, and HPV Impact of Second Primary Cancer following Primary Oropharyngeal Squamous Cell Carcinoma: A 20-Year Retrospective and Population-Based Study
Andersen, L., Jakobsen, K. K., Carlander, A. L. F., Garset-Zamani, M., Friborg, Jeppe Tang, Kiss, K., Marvig, R. L., Olsen, C., Nielsen, Finn Cilius, Andersen, E., Grønhøj, Christian & von Buchwald, Christian, 2023, In: Viruses. 15, 1, 34.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Intestinal metaplasia is a precursor lesion for sinonasal intestinal-type adenocarcinoma: genomic investigation of a case proving this hypothesis
Sjöstedt, S., Schmidt, A. Y., Vieira, Filipe Garrett, Woller, N. C., Nielsen, Finn Cilius & von Buchwald, Christian, Jan 2022, In: APMIS. 130, 1, p. 53-56 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
A catalog of curated breast cancer genes
Bose, M., Benada, Jan, Thatte, Jayashree Vijay, Kinalis, S., Ejlertsen, Bent Laursen, Nielsen, Finn Cilius, Sørensen, Claus Storgaard & Rossing, Caroline Maria, 2022, In: Breast Cancer Research and Treatment. 191, p. 431-441Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benchmarking full-length transcript single cell mRNA sequencing protocols
Probst, V., Simonyan, Arman, Pacheco, F., Guo, Yuliu, Nielsen, Finn Cilius & Bagger, F. O., 2022, In: BMC Genomics. 23, 860.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differences in gene expression despite identical histomorphology in sinonasal intestinal-type adenocarcinoma and metastases from colorectal adenocarcinoma
Sjöstedt, S., Vieira, Filipe Garrett, Karnov, K., Agander, T. K., Willemoe, G. L., Rohrberg, K. S., Nielsen, Finn Cilius & von Buchwald, Christian, 2022, In: APMIS. 130, 9, p. 551-559Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extensive genomic analysis in patients with KRAS-mutated solid tumors shows high frequencies of concurrent alterations and potential targets but has limited clinical impact
Jacobsen, I. C., Spanggaard, I., Højgaard, M., Belcaid, L., Qvortrup, Camilla, Yde, C. W., Schmidt, A. Y., Nielsen, Finn Cilius, Willemoe, G. L., Dam, M. S., Lassen, Ulrik Niels & Staal Rohrberg, K., 2022, In: Acta Oncologica. 61, 12, p. 1499-1506 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of specific high-risk human papillomavirus genotypes on survival in oropharyngeal cancer
Garset-Zamani, M., Carlander, A. F., Jakobsen, K. K., Friborg, Jeppe Tang, Kiss, K., Marvig, R. L., Olsen, C., Nielsen, Finn Cilius, Andersen, E., Grønhøj, Christian & von Buchwald, Christian, 2022, In: International Journal of Cancer. 150, 7, p. 1174-1183Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interpretable autoencoders trained on single cell sequencing data can transfer directly to data from unseen tissues
Walbech, J. S., Kinalis, S., Winther, Ole, Nielsen, Finn Cilius & Bagger, F. O., 2022, In: Cells. 11, 12 p., 85.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNA-9-3p: a novel predictor of neurological outcome after cardiac arrest
Beske, R. P., Bache, S., Meyer, M. A. S., Kjærgaard, Jesper, Bro-Jeppesen, J., Obling, L., Olsen, M. H., Rossing, Caroline Maria, Nielsen, Finn Cilius, Møller, Kirsten, Nielsen, N. & Hassager, Christian, 2022, In: European Heart Journal: Acute Cardiovascular Care. 11, 8, p. 609-616 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Personalized circulating tumor DNA in patients with hepatocellular carcinoma: a pilot study
Pommergaard, Hans-Christian L, Yde, C. W., Ahlborn, L. B., Andersen, C. L., Henriksen, T., Hasselby, Jane Preuss, Rostved, A. A., Sorensen, C. L., Rohrberg, K. S., Nielsen, Finn Cilius & Rasmussen, Anne, 2022, In: Molecular Biology Reports. 49, 2, p. 1609-1616 8 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Polygenic risk modeling for prediction of epithelial ovarian cancer risk
Dareng, E. O., Tyrer, J. P., Barnes, D. R., Jones, M. R., Yang, X., Aben, K. K. H., Adank, M. A., Agata, S., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Aravantinos, G., Arun, B. K., Augustinsson, A., Balmaña, J., Bandera, E. V., Barkardottir, R. B., Barrowdale, D., Beckmann, M. W., Beeghly-Fadiel, A. & 39 others, , 2022, In: European journal of human genetics : EJHG. 30, 3, p. 349-362 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting the tumor mutanome for personalized vaccination in a TMB low non-small cell lung cancer
McCann, K., Von Witzleben, A., Thomas, J., Wang, C., Wood, O., Singh, D., Boukas, K., Bendjama, K., Silvestre, N., Nielsen, Finn Cilius, Thomas, G., Sanchez-Elsner, T., Greenbaum, J., Schoenberger, S., Peters, B., Vijayanand, P., Savelyeva, N. & Ottensmeier, C., 2022, In: Journal for ImmunoTherapy of Cancer. 10, 3, 14 p., e003821.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor mutational burden and purity adjustment before and after treatment with temozolomide in 27 paired samples of glioblastoma: a prospective study
Nørøxe, D. S., Flynn, A., Yde, C. W., Østrup, O., Nielsen, Finn Cilius, Skjøth, Jane, Brennum, J., Hamerlik, P., Weischenfeldt, Joachim Lütken, Skovgaard Poulsen, H. & Lassen, Ulrik Niels, 2022, In: Molecular Oncology. 16, 1, p. 206-218Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers
GEMO Study Collaborators, G. S. C., EMBRACE Collaborators, E. C., kConFab Investigators, K. I., HEBON Investigators, H. I. & ABCTB Investigators, A. I., Dec 2021, In: Nature Communications. 12, 1, 22 p., 1078.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical implications of intrinsic molecular subtypes of breast cancer for sentinel node status
Rossing, M., Pedersen, C. B., Tvedskov, Tove Filtenborg, Vejborg, I., Talman, M. L., Olsen, L. R., Kroman, Niels Thorndahl, Nielsen, Finn Cilius, Jensen, M. B. & Ejlertsen, Bent Laursen, Dec 2021, In: Scientific Reports. 11, 1, 12 p., 2259.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Major driver mutations are shared between sinonasal intestinal-type adenocarcinoma and the morphologically identical colorectal adenocarcinoma
Sjöstedt, S., Schmidt, A. Y., Vieira, Filipe Garrett, Willemoe, G. L., Agander, T. K., Olsen, C., Nielsen, Finn Cilius & von Buchwald, Christian, Apr 2021, In: Journal of Cancer Research and Clinical Oncology. 147, 4, p. 1019-1027 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Achromobacter spp. genetic adaptation in cystic fibrosis
Gabrielaite, M., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marvig, R. L., 2021, In: Microbial genomics. 7, 7, 13 p., 000582.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data
Gabrielaite, M., Torp, M., Rasmussen, M., Andreu-Sánchez, S., Vieira, Filipe Garrett, Pedersen, C., Kinalis, S., Madsen, M., Yde, C., Rønn, O. L., Marvig, R., Østrup, O., Rossing, Caroline Maria, Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2021, bioRxiv, 29 p.Research output: Working paper › Preprint › Research
- Published
A comparison of tools for copy-number variation detection in germline whole exome and whole genome sequencing data
Gabrielaite, M., Torp, M. H., Rasmussen, Malthe Sebro, Andreu-Sánchez, S., Vieira, Filipe Garrett, Pedersen, C. B., Kinalis, S., Madsen, M. B., Kodama, M., Demircan, G. S., Simonyan, A., Yde, C. W., Olsen, L. R., Marvig, R. L., Østrup, O., Rossing, Caroline Maria, Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2021, In: Cancers. 13, 24, 6283.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A simple, safe and sensitive method for SARS-CoV-2 inactivation and RNA extraction for RT-qPCR
Kalnina, L., Mateu-Regué, À., Oerum, S., Hald, A., Gerstoft, Jan, Oerum, H., Nielsen, Finn Cilius & Iversen, A. K. N., 2021, In: APMIS. 129, 7, p. 393-400 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic alterations in human papillomavirus-positive and -negative conjunctival squamous cell carcinomas
Ramberg, Ingvild Margrethe Sellæg, Vieira, Filipe Garrett, Toft, Peter Bjerre, von Buchwald, Christian, Funding, M., Nielsen, Finn Cilius & Heegaard, Steffen, 2021, In: Investigative Ophthalmology and Visual Science. 62, 14, 11.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transmission and Antibiotic Resistance of Achromobacter in Cystic Fibrosis
Gabrielaite, M., Bartell, J. A., Nørskov-Lauritsen, N., Pressler, T., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marviga, R. L., 2021, In: Journal of Clinical Microbiology. 59, 4, e02911-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unveiling mRNP composition by fluorescence correlation and cross-correlation spectroscopy using cell lysates
Mateu-Regué, À., Christiansen, Jan, Bagger, F. O., Hellriegel, C. & Nielsen, Finn Cilius, 2021, In: Nucleic Acids Research. 49, 20, 15 p., e119.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants
Barnes, D. R., Rookus, M. A., Mcguffog, L., Leslie, G., Mooij, T. M., Dennis, J., Mavaddat, N., Adlard, J., Ahmed, M., Aittomäki, K., Andrieu, N., Andrulis, I. L., Arnold, N., Arun, B. K., Azzollini, J., Balmaña, J., Barkardottir, R. B., Barrowdale, D., Benitez, J., Berthet, P. & 31 others, , 1 Oct 2020, In: Genetics in Medicine. 22, 10, p. 1653-1666 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Germline RBBP8 variants associated with early-onset breast cancer compromise replication fork stability
Zarrizi, R., Higgs, M. R., Voßgröne, Karolin, Rossing, M., Bertelsen, B., Bose, M., Kousholt, A. N., Rösner, Heike Ilona, Network, T. C., Ejlertsen, Bent Laursen, Stewart, G. S., Nielsen, Finn Cilius & Sørensen, Claus Storgaard, 3 Aug 2020, In: The Journal of Clinical Investigation. 130, 8, p. 4069-4080 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
Zhang, H., Ahearn, T. U., Lecarpentier, J., Barnes, D., Beesley, J., Qi, G., Jiang, X., O'Mara, T. A., Zhao, N., Bolla, M. K., Dunning, A. M., Dennis, J., Wang, Q., Ful, Z. A., Aittomäki, K., Andrulis, I. L., Anton-Culver, H., Arndt, V., Aronson, K. J., Arun, B. K. & 31 others, , Jun 2020, In: Nature Genetics. 52, 6, p. 572-581 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor miRNA expression profile is related to vestibular schwannoma growth rate
Sass, H. C. R., Hansen, M., Borup, R., Nielsen, Finn Cilius & Cayé-Thomasen, Per, May 2020, In: Acta Neurochirurgica. 162, 5, p. 1187-1195 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Number of Signaling Pathways Altered by Driver Mutations in Chronic Lymphocytic Leukemia Impacts Disease Outcome
Brieghel, C., da Cunha-Bang, C., Yde, C. W., Schmidt, A. Y., Kinalis, S., Nadeu, F., Andersen, M. A., Jacobsen, L. O., Andersen, M. K., Pedersen, L. B., Delgado, J., Baumann, T., Mattsson, M., Mansouri, L., Rosenquist, R., Campo, E., Nielsen, Finn Cilius & Niemann, Carsten, 15 Mar 2020, In: Clinical Cancer Research. 26, 6, p. 1507-1515 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of Genomic Domains in BRCA1 and BRCA2 with Prostate Cancer Risk and Aggressiveness
Patel, V. L., Busch, E. L., Friebel, T. M., Cronin, A., Leslie, G., McGuffog, L., Adlard, J., Agata, S., Agnarsson, B. A., Ahmed, M., Aittomäki, K., Alducci, E., Andrulis, I. L., Arason, A., Arnold, N., Artioli, G., Arver, B., Auber, B., Azzollini, J., Balmaña, J. & 243 others, , 1 Feb 2020, In: Cancer Research. 80, 3, p. 624-638 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amplicon-Based NGS Panels for Actionable Cancer Target Identification in Follicular Cell-Derived Thyroid Neoplasia
Madsen, M. B., Kiss, K., Nielsen, Finn Cilius, Bennedbæk, F. N. & Rossing, M., 2020, In: Frontiers in Endocrinology. 11, 8 p., 146.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Cytoplasmic mRNPs revisited: Singletons and condensates
Mateu-Regue, A., Nielsen, Finn Cilius & Christiansen, Jan, 2020, In: BioEssays. 42, 12, 13 p., 2000097.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes
Fachal, L., Aschard, H., Beesley, J., Barnes, D. R., Allen, J., Kar, S., Pooley, K. A., Dennis, J., Michailidou, K., Turman, C., Soucy, P., Lemaçon, A., Lush, M., Tyrer, J. P., Ghoussaini, M., Marjaneh, M. M., Jiang, X., Agata, S., Aittomäki, K., Alonso, M. R. & 35 others, , 2020, In: Nature Genetics. 52, 1, p. 56-73 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene loss and acquisition in lineages of pseudomonas aeruginosa evolving in cystic fibrosis patient airways
Gabrielaite, M., Johansen, Helle Krogh, Molin, S., Nielsen, Finn Cilius & Marvig, R. L., 2020, In: mBio. 11, 5, p. 1-16 16 p., e02359-20.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic profiling of newly diagnosed glioblastoma patients and its potential for clinical utility – a prospective, translational study
Nørøxe, D. S., Yde, C. W., Østrup, O., Michaelsen, Signe Regner, Schmidt, A. Y., Kinalis, S., Torp, M. H., Skjøth‐Rasmussen, J., Brennum, J., Hamerlik, P., Poulsen, H. S., Nielsen, Finn Cilius & Lassen, Ulrik Niels, 2020, In: Molecular Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Spectrum of FANCM Protein Truncating Variants in European Breast Cancer Cases
Figlioli, G., Kvist, A., Tham, E., Soukupova, J., Kleiblova, P., Muranen, T. A., Andrieu, N., Azzollini, J., Balmaña, J., Barroso, A., Benítez, J., Bertelsen, B., Blanco, A., Bonanni, B., Borg, Å., Brunet, J., Calistri, D., Calvello, M., Chvojka, S., Cortesi, L. & 31 others, , 2020, In: Cancers. 12, 2, 10 p., 292.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The current epidemic of HPV-associated oropharyngeal cancer: An 18-year Danish population-based study with 2,169 patients
Zamani, M., Grønhøj, C., Jensen, D. H., Carlander, A. F., Agander, T., Kiss, K., Olsen, C., Baandrup, L., Nielsen, Finn Cilius, Andersen, E. V., Friborg, Jeppe Tang & von Buchwald, Christian, 2020, In: European Journal of Cancer. 134, p. 52-59Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome-wide association study of breast cancer risk by estrogen-receptor status
Feng, H., Gusev, A., Pasaniuc, B., Wu, L., Long, J., Abu-full, Z., Aittomäki, K., Andrulis, I. L., Anton-Culver, H., Antoniou, A. C., Arason, A., Arndt, V., Aronson, K. J., Arun, B. K., Asseryanis, E., Auer, P. L., Azzollini, J., Balmaña, J., Barkardottir, R. B., Barnes, D. R. & 37 others, , 2020, In: Genetic Epidemiology. 44, 5, p. 442-468Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ultra-fast detection and quantification of nucleic acids by amplification-free fluorescence assay
Uhd, J., Miotke, L., Ji, H. P., Dunaeva, M., Pruijn, G. J. M., Jørgensen, C. D., Kristoffersen, E. L., Birkedal, V., Yde, C. W., Nielsen, Finn Cilius, Hansen, J. & Astakhova, K., 2020, In: Analyst. 145, 17, p. 5836-5844 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variant in ERAP1 promoter region is associated with low expression in a patient with a Behçet-like MHC-I-opathy
Dimopoulou, C., Lundgren, Jens, Sundal, J., Ullum, H., Aukrust, P., Nielsen, Finn Cilius & Marvig, R. L., 2020, In: Journal of Human Genetics. 65, 3, p. 325-335 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Deep targeted sequencing of TP53 in chronic lymphocytic leukemia: clinical impact at diagnosis and at time of treatment
Brieghel, C., Kinalis, S., Yde, C. W., Schmidt, A. Y., Jønson, L., Andersen, M. A., da Cunha-Bang, C., Pedersen, L. B., Geisler, C. H., Nielsen, Finn Cilius & Niemann, Carsten, Apr 2019, In: Haematologica. 104, 4, p. 789-796 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of cell-free DNA for genomic tumor profiling: a feasibility study
Ahlborn, L. B., Rohrberg, K. S., Gabrielaite, M., Tuxen, I. V., Yde, C. W., Spanggaard, I., Santoni Rugiu, Eric, Nielsen, Finn Cilius, Lassen, Ulrik Niels, Mau-Sorensen, M. & Østrup, O., Feb 2019, In: OncoTarget. 10, 14, p. 1388-1398Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shared heritability and functional enrichment across six solid cancers
Jiang, X., Finucane, H. K., Schumacher, F. R., Schmit, S. L., Tyrer, J. P., Han, Y., Michailidou, K., Lesseur, C., Kuchenbaecker, K. B., Dennis, J., Conti, D. V., Casey, G., Gaudet, M. M., Huyghe, J. R., Albanes, D., Aldrich, M. C., Andrew, A. S., Andrulis, I. L., Anton-Culver, H., Antoniou, A. C. & 313 others, , 25 Jan 2019, In: Nature Communications. 10, 1, 23 p., 431.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell-free DNA in newly diagnosed patients with glioblastoma - a clinical prospective feasibility study
Nørøxe, D. S., Østrup, O., Yde, C. W., Ahlborn, L. B., Nielsen, Finn Cilius, Michaelsen, Signe Regner, Larsen, V. A., Skjøth-Rasmussen, J., Brennum, J., Hamerlik, P., Poulsen, H. S. & Lassen, Ulrik Niels, 2019, In: OncoTarget. 10, 43, p. 4397-4406 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Completeness of RET testing in patients with medullary thyroid carcinoma in Denmark 1997–2013: A nationwide study
Danish Thyroid Cancer Group (DATHYRCA), D. T. C. G. (., 2019, In: Clinical Epidemiology. 11, p. 93-99 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Copenhagen prospective personalized oncology (COPPO)—Clinical utility of using molecular profiling to select patients to phase I trials
Tuxen, I. V., Rohrberg, K. S., Oestrup, O., Ahlborn, L. B., Schmidt, A. Y., Spanggaard, I., Hasselby, Jane Preuss, Santoni Rugiu, Eric, Yde, C. W., Mau-Sørensen, M., Nielsen, Finn Cilius & Lassen, Ulrik Niels, 2019, In: Clinical Cancer Research. 25, 4, p. 1239-1247 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deconvolution of autoencoders to learn biological regulatory modules from single cell mRNA sequencing data
Kinalis, S., Nielsen, Finn Cilius, Winther, Ole & Bagger, F. O., 2019, In: BMC Bioinformatics. 20, 9 p., 379.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated mir-9 in Cerebrospinal Fluid is Associated With Poor Functional Outcome After Subarachnoid Hemorrhage
Bache, S., Rasmussen, R., Wolcott, Z., Rossing, M., Møgelvang, R., Tolnai, D., Hassager, Christian, Forman, Julie Lyng, Køber, Lars Valeur, Nielsen, Finn Cilius, Kimberly, W. T. & Møller, Kirsten, 2019, In: Stroke. 50, Supplement 1, 1 p., A149.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer
EMBRACE Collaborators, E. C., GC-HBOC Study Collaborators, G. S. C., GEMO Study Collaborators, G. S. C., ABCTB Investigators, A. I., HEBON Investigators, H. I. & BCFR Investigators, B. I., 2019, In: Nature Communications. 10, 1, 18 p., 1741.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomisk medicin
Nielsen, Finn Cilius, 2019, In: Ugeskrift for Laeger. 181, 5 p., V01190031.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Height and body mass index as Modifiers of breast cancer risk in BRCA1/2 mutation carriers: A Mendelian randomization study
GEMO Study Collaborators, HEBON, EMBRACE, G. S. C. H. E., 2019, In: Journal of the National Cancer Institute. 111, 4, p. 350-364 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High frequency of pathogenic germline variants within homologous recombination repair in patients with advanced cancer
Bertelsen, B., Tuxen, I. V., Yde, C. W., Gabrielaite, M., Torp, M. H., Kinalis, S., Oestrup, O., Rohrberg, K., Spangaard, I., Santoni Rugiu, Eric, Wadt, Karin Anna Wallentin, Mau-Sorensen, M., Lassen, Ulrik Niels & Nielsen, Finn Cilius, 2019, In: npj Genomic Medicine. 4, 1, 11 p., 13.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers
kConFab Investigators, K. I., HEBON Investigators, H. I., GEMO Study Collaborators, G. S. C. & EMBRACE Collaborators, E. C., 2019, In: British Journal of Cancer. 121, 2, p. 180-192 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma total cell-free DNA is a prognostic biomarker of overall survival in metastatic solid tumour patients
Viller Tuxen, I., Barlebo Ahlborn, L., Mau-Soerensen, M., Staal Rohrberg, K., Nielsen, Finn Cilius, Oestrup, O., Westmose Yde, C., Richter Vogelius, I. & Lassen, Ulrik Niels, 2019, In: British Journal of Cancer. 121, 2, p. 125-130 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication of newly proposed TNM staging system for medullary thyroid carcinoma: a nationwide study
Mathiesen, J. S., Kroustrup, J. P., Vestergaard, P., Poulsen, P. L., Rasmussen, Å. K., Feldt-Rasmussen, Ulla, Schytte, S., Londero, S. C., Pedersen, H. B., Hahn, Christoffer Holst, Bentzen, J., Möller, S., Gaustadnes, M., Rossing, M., Nielsen, Finn Cilius, Brixen, K. & Godballe, C., 2019, In: Endocrine Connections. 8, 1, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single mRNP Analysis Reveals that Small Cytoplasmic mRNP Granules Represent mRNA Singletons
Mateu-Regué, À., Christiansen, Jan, Bagger, F. O., Winther, O., Hellriegel, C. & Nielsen, Finn Cilius, 2019, In: Cell Reports. 29, 3, p. 736-748, e1-e4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Survival and Long-Term Biochemical Cure in Medullary Thyroid Carcinoma in Denmark 1997-2014: A Nationwide Study
Mathiesen, J. S., Kroustrup, J. P., Vestergaard, P., Stochholm, K., Poulsen, P. L., Rasmussen, Å. K., Feldt-Rasmussen, Ulla, Schytte, S., Londero, S. C., Pedersen, H. B., Hahn, Christoffer Holst, Bentzen, J., Möller, S., Gaustadnes, M., Rossing, M., Nielsen, Finn Cilius, Brixen, K., Frederiksen, A. L. & Godballe, C., 2019, In: Thyroid. 29, 3, p. 368-377Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer
ABCTB Investigators, A. I., GEMO Study Collaborators, G. S. C. & kConFab, K., 2019, In: npj Breast Cancer. 5, 1, 14 p., 38.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole genome sequencing of breast cancer
Rossing, M., Sørensen, Claus Storgaard, Ejlertsen, Bent Laursen & Nielsen, Finn Cilius, 2019, In: APMIS - Journal of Pathology, Microbiology and Immunology. 127, 5, p. 303-315 13 p.Research output: Contribution to journal › Review › Research › peer-review
- 2018
- Published
A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk
et al., E. A., 15 Sep 2018, In: Cancer Research. 78, 18, p. 5419-5430 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of basal-like subtype in a Danish consecutive primary breast cancer cohort
Kinalis, S., Nielsen, Finn Cilius, Talman, M. L., Ejlertsen, B. & Rossing, M., 2018, In: Acta Oncologica. 57, 1, p. 51-57Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating tumor DNA as a marker of treatment response in BRAF V600E mutated non-melanoma solid tumors
Ahlborn, L. B., Tuxen, I. V., Mouliere, F., Kinalis, S., Schmidt, A. Y., Rohrberg, K. S., Santoni Rugiu, Eric, Nielsen, Finn Cilius, Lassen, Ulrik Niels, Yde, C. W., Oestrup, O. & Mau-Sorensen, M., 2018, In: OncoTarget. 9, 66, p. 32570-32579Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deep sequencing of human papillomavirus positive loco-regionally advanced oropharyngeal squamous cell carcinomas reveals novel mutational signature
Grønhøj, C., Jensen, D. H., Agander, T., Kiss, K., Høgdall, Estrid Vilma Solyom, Specht, Lena, Bagger, F. O., Nielsen, Finn Cilius & von Buchwald, Christian, 2018, In: BMC Cancer. 18, 1, p. 1-10 10 p., 640.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic alterations accompanying tumour evolution in colorectal cancer: tracking the differences between primary tumours and synchronous liver metastases by whole-exome sequencing
Mogensen, M. B., Rossing, M., Østrup, O., Larsen, P. N., Heiberg Engel, P. J., Jørgensen, Lars Nannestad, Høgdall, Estrid Vilma Solyom, Eriksen, J., Ibsen, Per Holger, Jess, P., Grauslund, M., Nielsen, H. J., Nielsen, Finn Cilius, Vainer, B. & Osterlind, K., 2018, In: BMC Cancer. 18, 13 p., 752.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Importance of comprehensive molecular profiling for clinical outcome in children with recurrent cancer
Østrup, O., Nysom, K., Scheie, David, Schmidt, A. Y., Mathiasen, R., Hjalgrim, L. L., Olsen, T. E., Skjøth-Rasmussen, J., Henriksen, B. M., Nielsen, Finn Cilius, Wehner, P. S., Schrøder, H., Sehested, A. M., Rechnitzer, C. & Rossing, M., 2018, In: Frontiers in Pediatrics. 6, 8 p., 114.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incidence and prevalence of multiple endocrine neoplasia 2a in denmark 1901–2014: A nationwide study
Mathiesen, J. S., Kroustrup, J. P., Vestergaard, P., Stochholm, K., Poulsen, P. L., Rasmussen, Å. K., Feldt-Rasmussen, Ulla, Schytte, S., Pedersen, H. B., Hahn, Christoffer Holst, Bentzen, J., Möller, S., Gaustadnes, M., Rossing, M., Nielsen, Finn Cilius, Brixen, K., Frederiksen, A. L. & Godballe, C., 2018, In: Clinical Epidemiology. 10, p. 1479-1487 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incidence and prevalence of sporadic and hereditary MTC in Denmark 1960-2014: a nationwide study
Mathiesen, J. S., Kroustrup, J. P., Vestergaard, P., Stochholm, K., Poulsen, P. L., Rasmussen, Å. K., Feldt-Rasmussen, U., Schytte, S., Londero, S. C., Pedersen, H. B., Hahn, C. H., Djurhuus, B. D., Bentzen, J., Möller, S., Gaustadnes, M., Rossing, M., Nielsen, F. C., Brixen, K., Frederiksen, A. L., Godballe, C. & 1 others, , 2018, In: Endocrine Connections. 7, 6, p. 829-839 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MicroRNA-based classifiers for diagnosis of oral cavity squamous cell carcinoma in tissue and plasma
Pedersen, N. J., Jensen, D. H., Lelkaitis, G., Kiss, K., Charabi, Birgitte Wittenborg, Ullum, H., Specht, Lena, Schmidt, A. Y., Nielsen, Finn Cilius & von Buchwald, Christian, 2018, In: Oral Oncology. 83, p. 46-52Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular subtyping of breast cancer improves identification of both high and low risk patients
Rossing, M., Østrup, O., Majewski, W. W., Kinalis, S., Jensen, M. B., Knoop, A., Kroman, Niels Thorndahl, Talman, M. L., Hansen, T. V. O., Ejlertsen, B. & Nielsen, Finn Cilius, 2018, In: Acta Oncologica. 57, 1, p. 58-66Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational landscape assessed in tumor tissue and cell-free DNA during neratinib treatment of patients with HER2 mutated solid tumors
Spanggaard, I., Oestrup, O., Bertelsen, B., Rohrberg, K. S., de Schmidt, A. Y., Tuxen, I. V., Ahlborn, L. B., Hasselby, Jane Preuss, Santoni Rugiu, Eric, Marvig, R. L., Lassen, Ulrik Niels, Nielsen, Finn Cilius, Yde, C. W. & Mau-Sørensen, M., 2018, In: European Journal of Cancer. 103, Suppl. 1, p. E142-E143 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations
EMBRACE, E., 2018, In: Human Mutation. 39, 5, p. 593-620 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using microarray-based subtyping methods for breast cancer in the era of high-throughput RNA sequencing
Pedersen, C. B., Nielsen, Finn Cilius, Rossing, M. & Olsen, L. R., 2018, In: Molecular Oncology. 12, 12, p. 2136-2146 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Correlation between HPV status at T and N sites of oropharyngeal squamous cell carcinomas
Josiassen, M. V., Charabi, Birgitte Wittenborg, Lajer, C. B., Garnaes, E., Hamilton Therkildsen, M., Norrild, B., Specht, Lena, Nielsen, Finn Cilius & von Buchwald, Christian, Dec 2017, In: Acta Oto-Laryngologica. 137, 12, p. 1260-1264 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Founder effect of the RETC611Y mutation in multiple endocrine neoplasia 2A in Denmark: a nationwide Study
Sloth Mathiesen, J., Kroustrup, J. P., Vestergaard, P., Krag, K. S., Poulsen, P. L., Rasmussen, Å. K., Feldt-Rasmussen, Ulla, Gaustadnes, M., Ørntoft, T. F., Rossing, M., Nielsen, Finn Cilius, Albrechtsen, Anders, Brixen, K., Godballe, C. & Frederiksen, A. L., Dec 2017, In: Thyroid. 27, 12, p. 1505-1510 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Next-Generation Sequencing-Based Detection of Germline Copy Number Variations in BRCA1/BRCA2: Validation of a One-Step Diagnostic Workflow
Schmidt, A. Y., Hansen, T. V. O., Ahlborn, L. B., Jønson, L., Yde, C. W. & Nielsen, Finn Cilius, Nov 2017, In: The Journal of molecular diagnostics : JMD. 19, 6, p. 809-816 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Application of whole-exome sequencing to direct the specific functional testing and diagnosis of rare inherited bleeding disorders in patients from the Öresund Region, Scandinavia
Leinøe, E., Zetterberg, E., Kinalis, S., Østrup, O., Kampmann, P., Norström, E., Andersson, N., Klintman, J., Qvortrup, Klaus, Nielsen, Finn Cilius & Rossing, M., Oct 2017, In: British Journal of Haematology. 179, 2, p. 308-322 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression profiling in patients with polymyalgia rheumatica before and after symptom-abolishing glucocorticoid treatment
Kreiner, F. F., Borup, R., Nielsen, Finn Cilius, Schjerling, P. & Galbo, Henrik, 7 Aug 2017, In: BMC Musculoskeletal Disorders. 18, 19 p., 341.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of copy number alterations in cell-free tumor DNA from plasma
Østrup, O., Ahlborn, L. B., Lassen, Ulrik Niels, Mau-Sørensen, M. & Nielsen, Finn Cilius, Jun 2017, In: BBA Clinical. 7, p. 120-126 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuronal Fibers and Neurotransmitter Receptor Expression in the Human Endolymphatic Sac
Møller, M. N., Kirkeby, Svend, Vikeså, J., Nielsen, Finn Cilius & Cayé-Thomasen, Per, Jun 2017, In: Otology & Neurotology. 38, 5, p. 765-773 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human endolymphatic sac expresses natriuretic peptides
Møller, M. N., Kirkeby, Svend, Vikeså, J., Nielsen, Finn Cilius & Cayé-Thomasen, Per, Jun 2017, In: The Laryngoscope. 127, 6, p. E201-E208Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution of RET Mutations in Multiple Endocrine Neoplasia 2 in Denmark 1994-2014: A Nationwide Study
Mathiesen, J. S., Kroustrup, J. P., Vestergaard, P., Stochholm, K., Poulsen, P. L., Rasmussen, Å. K., Feldt-Rasmussen, Ulla, Gaustadnes, M., Ørntoft, T. F., van Overeem Hansen, T., Nielsen, Finn Cilius, Brixen, K., Godballe, C. & Frederiksen, A. L., Feb 2017, In: Thyroid. 27, 2, p. 215-223 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Continuing rise in oropharyngeal cancer in a high HPV prevalence area: A Danish population-based study from 2011 to 2014
Carlander, A. F., Larsen, C. G., Jensen, D. H., Garnaes, E., Kiss, K., Andersen, L., Olsen, C. H., Franzmann, M., Høgdall, Estrid Vilma Solyom, Kjær, Susanne Krüger, Norrild, B., Specht, Lena, Andersen, E., Hansen, T. V. O., Nielsen, Finn Cilius & von Buchwald, Christian, Jan 2017, In: European Journal of Cancer. 70, p. 75-82Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression, signal transduction pathways and functional networks associated with growth of sporadic vestibular schwannomas
Sass, H. C. R., Borup, R., Alanin, M., Nielsen, Finn Cilius & Cayé-Thomasen, Per, Jan 2017, In: Journal of Neuro-Oncology. 131, 2, p. 283-292 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Concordance of mutation detection in circulating tumor DNA in early clinical trials using different blood collection protocols
Ahlborn, L. B., Madsen, M., Jonson, L., Nielsen, Finn Cilius, Lassen, Ulrik Niels, Yde, C. W. & Mau-Sorensen, M., 2017, In: Clinical Laboratory. 63, 10, p. 1755-1759Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic screening of the FLCN gene identify six novel variants and a Danish founder mutation
Rossing, M., Albrechtsen, Anders, Skytte, A., Jensen, U. B., Ousager, L. B., Gerdes, Anne-Marie Axø, Nielsen, Finn Cilius & Hansen, T. V. O., 2017, In: Journal of Human Genetics. 62, p. 151-157 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incidence and prevalence of multiple endocrine neoplasia 2B in Denmark: a nationwide study
Mathiesen, J. S., Kroustrup, J. P., Vestergaard, P., Madsen, M., Stochholm, K., Poulsen, P. L., Krogh Rasmussen, Å., Feldt-Rasmussen, Ulla, Schytte, S., Pedersen, H. B., Hahn, Christoffer Holst, Bentzen, J., Gaustadnes, M., Ørntoft, T. F., Hansen, T. V. O., Nielsen, Finn Cilius, Brixen, K., Frederiksen, A. L. & Godballe, C., 2017, In: Endocrine - Related Cancer. 24, 7, p. L39-L42Research output: Contribution to journal › Letter › Research › peer-review
- Published
MicroRNA Changes in Cerebrospinal Fluid After Subarachnoid Hemorrhage
Bache, S., Rasmussen, R., Rossing, M., Laigaard, F. P., Nielsen, Finn Cilius & Møller, Kirsten, 2017, In: Stroke. 48, 9, p. 2391-2398Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
A new NFIA:RAF1 fusion activating the MAPK pathway in pilocytic astrocytoma
Yde, C. W., Sehested, A., Regué, À. M., Østrup, O., Scheie, David, Nysom, K., Nielsen, Finn Cilius & Rossing, M., Oct 2016, In: Cancer genetics and cytogenetics. 209, 10, p. 440-444 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Hereditary breast and ovarian cancer: new genes in confined pathways
Nielsen, Finn Cilius, Hansen, T. V. O. & Sørensen, Claus Storgaard, Sep 2016, In: Nature Reviews. Cancer. 16, 9, p. 599-612 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Progression of motor axon dysfunction and ectopic Na(v)1.8 expression in a mouse model of Charcot-Marie-Tooth disease 1B
Rosberg, M. R., Alvarez Herrero, S., Klein, D., Nielsen, Finn Cilius, Martini, R., Levinson, S. R., Krarup, Christian & Moldovan, Mihai, Sep 2016, In: Neurobiology of Disease. 93, p. 201-214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of histamine receptors in the human endolymphatic sac: the molecular rationale for betahistine use in Menieres disease
Møller, M. N., Kirkeby, Svend, Vikeså, J., Nielsen, Finn Cilius & Cayé-Thomasen, Per, Jul 2016, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 273, 7, p. 1705-10 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression risk signatures maintain prognostic power in multiple myeloma despite microarray probe set translation
Hermansen, N. E. U., Borup, R., Andersen, M. K., Vangsted, Annette Juul, Clausen, T. N., Kristensen, D. L., Nielsen, Finn Cilius & Gimsing, P., Jun 2016, In: International Journal of Laboratory Hematology. 38, 3, p. 298-307 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer
Hollestelle, A., van der Baan, F. H., Berchuck, A., Johnatty, S. E., Aben, K. K., Agnarsson, B. A., Aittomäki, K., Alducci, E., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Antoniou, A. C., Apicella, C., Arndt, V., Arnold, N., Arun, B. K., Arver, B., Ashworth, A., Baglietto, L., Balleine, R. & 31 others, , May 2016, In: Gynecologic Oncology. 141, 2, p. 386–401Research output: Contribution to journal › Review › Research › peer-review
- Published
The trans fatty acid elaidate affects the global DNA methylation profile of cultured cells and in vivo
Flores-Sierra, J., Arredondo-Guerrero, M., Cervantes-Paz, B., Rodríguez-Ríos, D., Alvarado-Caudillo, Y., Nielsen, Finn Cilius, Wrobel, K., Wrobel, K., Zaina, S. & Lund, G., 12 Apr 2016, In: Lipids in Health and Disease. 15, 7 p., 75.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of six pathogenic RAD51C mutations via mutational screening of 1228 Danish individuals with increased risk of hereditary breast and/or ovarian cancer
Jønson, L., Ahlborn, L. B., Steffensen, A. Y., Djursby, M., Ejlertsen, B., Timshel, S., Nielsen, Finn Cilius, Gerdes, Anne-Marie Axø & Hansen, T. V. O., Jan 2016, In: Breast Cancer Research and Treatment. 155, 2, p. 215-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 6797
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IMP3 RNP safe houses prevent miRNA-directed HMGA2 mRNA decay in cancer and development
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RNA assemblages orchestrate complex cellular processes
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Cancers of unknown primary origin (CUP) are characterized by chromosomal instability (CIN) compared to metastasis of know origin
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