David Michael Gay
Assistant Professor
Lund Group
Ole Maaløes Vej 5, 2200 København N.
Member of:
- 2023
- Published
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target
Vande Voorde, J., Steven, R. T., Najumudeen, A. K., Ford, C. A., Dexter, A., Gonzalez-Fernandez, A., Nikula, C. J., Xiang, Y., Ford, L., Maneta Stavrakaki, S., Gilroy, K., Zeiger, L. B., Pennel, K., Hatthakarnkul, P., Elia, E. A., Nasif, A., Murta, T., Manoli, E., Mason, S., Gillespie, M. & 34 others, , 2023, In: Nature Metabolism. 5, 8, p. 1303-1318 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging
Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, , 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions
Häfner, Sophia Julia, Jansson, Martin David, Altinel, Kübra, Andersen, Kasper Langebjerg, Abay-Nørgaard, Zehra Caldwell, Ménard, Patrice, Fontenas, M., Sørensen, Daniel Madriz, Gay, David Michael, Arendrup, Frederic Schrøder, Tehler, D., Krogh, Nicolai, Nielsen, Henrik, Kraushar, M. L., Kirkeby, Agnete & Lund, Anders H., 2023, In: Developmental Cell. 58, 17, p. 1593-1609.e9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Role of WNT Pathway Mutations in Cancer Development and an Overview of Therapeutic Options
Groenewald, Wibke, Lund, Anders H. & Gay, David Michael, 2023, In: Cells. 12, 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Translational control through ribosome heterogeneity and functional specialization
Gay, David Michael, Lund, Anders H. & Jansson, Martin David, 2022, In: Trends in Biochemical Sciences. 47, 1, p. 66-81Research output: Contribution to journal › Review › Research › peer-review
- 2021
- Published
Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
Knight, J. R. P., Vlahov, N., Gay, David Michael, Ridgway, R. A., Faller, W. J., Proud, C., Mallucci, G. R., von der Haar, T., Smales, C. M., Willis, A. E. & Sansom, O. J., Dec 2021, In: eLife. 10, 25 p., e69729.Research output: Contribution to journal › Journal article › Research › peer-review
MNK inhibition sensitizes KRAS-Mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and C-MYC expression
Knight, J. R. P., Alexandrou, C., Skalka, G. L., Vlahov, N., Pennel, K., Officer, L., Teodosio, A., Kanellos, G., Gay, D. M., May-Wilson, S., Smith, E. M., Najumudeen, A. K., Gilroy, K., Ridgway, R. A., Flanagan, D. J., Smith, R. C. L., McDonald, L., Mackay, C., Cheasty, A., McArthur, K. & 19 others, , 2021, In: Cancer Discovery. 11, 5, p. 1228-1247 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer
Najumudeen, A. K., Ceteci, F., Fey, S. K., Gay, David Michael & CRUK Rosetta Grand Challenge Consortium, C. R. G. C. C., 2021, In: Nature Genetics. 53, 1, p. 16-26 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 208970898
Most downloads
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35
downloads
ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
32
downloads
Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
12
downloads
The Role of WNT Pathway Mutations in Cancer Development and an Overview of Therapeutic Options
Research output: Contribution to journal › Journal article › Research › peer-review
Published