David Michael Gay

David Michael Gay

Assistant Professor

Member of:

    ORCID: 0000-0002-7407-1245

    Publication year:
    All
    1 - 8 out of 8Page size: 10
    1. 2023
    2. Published

      Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeutic target

      Vande Voorde, J., Steven, R. T., Najumudeen, A. K., Ford, C. A., Dexter, A., Gonzalez-Fernandez, A., Nikula, C. J., Xiang, Y., Ford, L., Maneta Stavrakaki, S., Gilroy, K., Zeiger, L. B., Pennel, K., Hatthakarnkul, P., Elia, E. A., Nasif, A., Murta, T., Manoli, E., Mason, S., Gillespie, M. & 34 others, Lannagan, T. R. M., Vlahov, N., Ridgway, R. A., Nixon, C., Raven, A., Mills, M., Athineos, D., Kanellos, G., Nourse, C., Gay, David Michael, Hughes, M., Burton, A., Yan, B., Sellers, K., Wu, V., De Ridder, K., Shokry, E., Huerta Uribe, A., Clark, W., Clark, G., Kirschner, K., Thienpont, B., Li, V. S. W., Maddocks, O. D. K., Barry, S. T., Goodwin, R. J. A., Kinross, J., Edwards, J., Yuneva, M. O., Sumpton, D., Takats, Z., Campbell, A. D., Bunch, J. & Sansom, O. J., 2023, In: Nature Metabolism. 5, 8, p. 1303-1318 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging

      Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, Lund, Anders H., Treebak, Jonas Thue, Olsen, Jesper Velgaard, Poulsen, Steen Seier, Pownall, M. E., Jensen, Benjamin Anderschou Holbech, Clemmensen, Christoffer, Gerhart-Hines, Zach, Gatfield, D. & Bekker-Jensen, Simon Holst, 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Ribosomal RNA 2′-O-methylation dynamics impact cell fate decisions

      Häfner, Sophia Julia, Jansson, Martin David, Altinel, Kübra, Andersen, Kasper Langebjerg, Abay-Nørgaard, Zehra Caldwell, Ménard, Patrice, Fontenas, M., Sørensen, Daniel Madriz, Gay, David Michael, Arendrup, Frederic Schrøder, Tehler, D., Krogh, Nicolai, Nielsen, Henrik, Kraushar, M. L., Kirkeby, Agnete & Lund, Anders H., 2023, In: Developmental Cell. 58, 17, p. 1593-1609.e9

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      The Role of WNT Pathway Mutations in Cancer Development and an Overview of Therapeutic Options

      Groenewald, Wibke, Lund, Anders H. & Gay, David Michael, 2023, In: Cells. 12, 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. 2022
    7. Published

      Translational control through ribosome heterogeneity and functional specialization

      Gay, David Michael, Lund, Anders H. & Jansson, Martin David, 2022, In: Trends in Biochemical Sciences. 47, 1, p. 66-81

      Research output: Contribution to journal › Review › Research › peer-review

    8. 2021
    9. Published

      Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K

      Knight, J. R. P., Vlahov, N., Gay, David Michael, Ridgway, R. A., Faller, W. J., Proud, C., Mallucci, G. R., von der Haar, T., Smales, C. M., Willis, A. E. & Sansom, O. J., Dec 2021, In: eLife. 10, 25 p., e69729.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. MNK inhibition sensitizes KRAS-Mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and C-MYC expression

      Knight, J. R. P., Alexandrou, C., Skalka, G. L., Vlahov, N., Pennel, K., Officer, L., Teodosio, A., Kanellos, G., Gay, D. M., May-Wilson, S., Smith, E. M., Najumudeen, A. K., Gilroy, K., Ridgway, R. A., Flanagan, D. J., Smith, R. C. L., McDonald, L., Mackay, C., Cheasty, A., McArthur, K. & 19 others, Stanway, E., Leach, J. D., Jackstadt, R., Waldron, J. A., Campbell, A. D., Vlachogiannis, G., Valeri, N., Haigis, K. M., Sonenberg, N., Proud, C. G., Jones, N. P., Swarbrick, M. E., McKinnon, H. J., Faller, W. J., Quesne, J. L., Edwards, J., Willis, A. E., Bushell, M. & Sansom, O. J., 2021, In: Cancer Discovery. 11, 5, p. 1228-1247 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer

      Najumudeen, A. K., Ceteci, F., Fey, S. K., Gay, David Michael & CRUK Rosetta Grand Challenge Consortium, C. R. G. C. C., 2021, In: Nature Genetics. 53, 1, p. 16-26 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    ID: 208970898