Darryl S Pickering
Associate Professor
Molecular and Cellular Pharmacology
Jagtvej 160, København Ø
- 2014
- Published
Analogues of 3-Hydroxyisoxazole-Containing Glutamate Receptor Ligands Based on the 3-Hydroxypyrazole-Moiety: Design, Synthesis and Pharmacological Characterization
Jørgensen, L., Nielsen, Birgitte, Pickering, Darryl S, Kristensen, Anders Skov, Frydenvang, Karla Andrea, Madsen, Ulf & Clausen, Rasmus Prætorius, 2014, In: Neurochemical Research. 39, 10, p. 1895-1905 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L-Asp is a useful tool in the purification of the ionotropic glutamate receptor A2 ligand-binding domain
Krintel, C., Frydenvang, Karla Andrea, Ceravalls de Rabassa, A., Kaern, A. M., Gajhede, Michael, Pickering, Darryl S & Kastrup, Jette Sandholm Jensen, 27 Mar 2014, In: F E B S Journal. p. 2422–2430 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design, synthesis and in vitro pharmacology of GluK1 and GluK3 antagonists. Studies towards the design of subtype-selective antagonists through 2-carboxyethyl-phenylalanines with substituents interacting with non-conserved residues in the GluK binding sites
Sköld, N., Nielsen, Birgitte, Olsen, J., Han, L., Olsen, L., Madsen, Ulf, Kristensen, Jesper Langgaard, Pickering, Darryl S & Johansen, Tommy Nørskov, 2 Aug 2014, In: Bioorganic & Medicinal Chemistry. 22, 19, p. 5368-5377 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular recognition of two 2,4-syn-functionalized (S)-glutamate analogues by the kainate receptor GluK3 ligand-binding domain
Venskutonyte, R., Larsen, A. P., Frydenvang, Karla Andrea, Gajhede, Michael, Gefflaut, T., Pickering, Darryl S, Bunch, Lennart & Kastrup, Jette Sandholm Jensen, 2014, In: ChemMedChem. 9, 10, p. 2254-2259 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Forster Resonance Energy Transfer (FRET) Analysis of Dual CFP/YFP Labeled AMPA Receptors Reveals Structural Rearrangement within the C-Terminal Domain during Receptor Activation
Zachariassen, L. G., Katchan, M., Plested, A., Pickering, Darryl S & Kristensen, Anders Skov, 16 Feb 2014. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- 2013
- Published
UCCB01-125, a dimeric inhibitor of PSD-95, reduces inflammatory pain without disrupting cognitive or motor performance: Comparison with the NMDA receptor antagonist MK-801
Andreasen T., Jesper, Bach, Anders, Gynther, M., Nasser, A., Mogensen, J., Strømgaard, Kristian & Pickering, Darryl S, Apr 2013, In: Neuropharmacology. 67, p. 193-200 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does increasing the ratio of AMPA-to-NMDA receptor mediated neurotransmission engender antidepressant action? Studies in the mouse forced swim and tail suspension tests
Andreasen T., Jesper, Gynther, M. O. O., Rygaard, A., Bøgelund, T., Nielsen, S. D., Clausen, Rasmus Prætorius, Mogensen, J. & Pickering, Darryl S, 2013, In: Neuroscience Letters. 546, p. 6-10 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chemo-enzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters
Assaf, Z., Larsen, A. P., Venskutonyte, R., Han, L., Abrahamsen, B., Nielsen, Birgitte, Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Jensen, Anders A., Pickering, Darryl S, Frydenvang, Karla Andrea, Gefflaut, T. & Bunch, Lennart, 2013, In: Journal of Medicinal Chemistry. 56, 4, p. 1614-1628Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum: Chemoenzymatic synthesis of new 2,4- syn -functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters (Journal of Medicinal Chemistry (2013) 56 (1614-1628))
Assaf, Z., Larsen, A. P., Venskutonyteì, R., Han, L., Abrahamsen, B., Nielsen, Birgitte, Gajhede, Michael, Kastrup, Jette Sandholm Jensen, Jensen, A. A., Pickering, Darryl S, Frydenvang, Karla Andrea, Gefflaut, T. & Bunch, Lennart, 25 Jul 2013, In: Journal of Medicinal Chemistry. 56, 14, p. 5985 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Studies on an (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonist IKM-159: asymmetric synthesis, neuroactivity, and structural characterization
Juknaite, L., Sugamata, Y., Tokiwa, K., Ishikawa, Y., Takamizawa, S., Eng, A., Sakai, R., Pickering, Darryl S, Frydenvang, Karla Andrea, Swanson, G. T., Kastrup, Jette Sandholm Jensen & Oikawa, M., 2013, In: Journal of Medicinal Chemistry. 56, 6, p. 2283-2293Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1299533
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Investigation of the presence and antinociceptive function of muscarinic acetylcholine receptors in the African naked mole-rat (Heterocephalus glaber)
Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype
Research output: Contribution to journal › Journal article › Research › peer-review
Published