Chuna Ram Choudhary
professor, group leader
Choudhary Group
Blegdamsvej 3, 2200 København N., Bygning 6, Building: 06-6-14
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Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits
Acosta-Alvear, D., Cho, M. Y., Wild, T., Buchholz, T. J., Lerner, A. G., Simakova, O., Hahn, J., Korde, N., Landgren, O., Maric, I., Choudhary, Chuna Ram, Walter, P., Weissman, J. S. & Kampmann, M., 1 Sep 2015, In : eLife. 4, p. 1-19 e08153.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response
Beli, P., Lukashchuk, N., Wagner, S. A., Weinert, B. T., Olsen, Jesper Velgaard, Baskcomb, L., Mann, Matthias, Jackson, S. P. & Choudhary, Chuna Ram, 2012, In : Molecular Cell. 46, 2, p. 212-25 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response
Blasius, M., Wagner, S. A., Choudhary, Chuna Ram, Bartek, J. & Jackson, S. P., 4 Sep 2014, In : Genes & Development. 28, 18, p. 1977-1982 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A phospho-proteomic screen identifies substrates of the checkpoint kinase Chk1
Blasius, M., Forment, J. V., Thakkar, N., Wagner, S. A., Choudhary, Chuna Ram & Jackson, S. P., 2011, In : Genome Biology (Online Edition). 12, 8, p. R78Research output: Contribution to journal › Journal article › Research › peer-review
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p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage
Borisova, M. E., Voigt, A., Tollenaere, M. A. X., Sahu, S. K., Juretschke, T., Kreim, N., Mailand, Niels, Choudhary, Chuna Ram, Bekker-Jensen, Simon Holst, Akutsu, M., Wagner, S. A. & Beli, P., 2018, In : Nature Communications. 9, p. 1-16 16 p., 1017.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells
Bursomanno, S., Beli, P., Khan, A. M., Minocherhomji, S., Wagner, S. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chuna Ram, Hickson, Ian David & Liu, Ying, Jan 2015, In : DNA Repair. 25, p. 84-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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STK3 is a therapeutic target for a subset of acute myeloid leukemias
Camgoz, A., Paszkowski-Rogacz, M., Satpathy, S., Wermke, M., Hamann, M. V., von Bonin, M., Choudhary, Chuna Ram, Knapp, S. & Buchholz, F., 2018, In : OncoTarget. 9, 39, p. 25458-25473 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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lncRNA Panct1 Maintains Mouse Embryonic Stem Cell Identity by Regulating TOBF1 Recruitment to Oct-Sox Sequences in Early G1
Chakraborty, D., Paszkowski-Rogacz, M., Berger, N., Ding, L., Mircetic, J., Fu, J., Iesmantavicius, V., Choudhary, Chuna Ram, Anastassiadis, K., Stewart, A. F. & Buchholz, F., 12 Dec 2017, In : Cell Reports. 21, 11, p. 3012-3021 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lysine acetylation targets protein complexes and co-regulates major cellular functions
Choudhary, Chuna Ram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In : Science. 325, 5942, p. 834-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Decoding signalling networks by mass spectrometry-based proteomics
Choudhary, Chuna Ram & Mann, Matthias, 1 Jun 2010, In : Nature Reviews. Molecular Cell Biology. 11, 6, p. 427-39 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes
Choudhary, Chuna Ram, Olsen, Jesper Velgaard, Brandts, C., Cox, J., Reddy, P. N. G., Böhmer, F. D., Gerke, V., Schmidt-Arras, D., Berdel, W. E., Müller-Tidow, C., Mann, Matthias & Serve, H., 2009, In : Molecular Cell. 36, 2, p. 326-39 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The growing landscape of lysine acetylation links metabolism and cell signalling
Choudhary, Chuna Ram, Weinert, B. T., Nishida, Y., Verdin, E. & Mann, Matthias, 23 Jul 2014, In : Nature Reviews. Molecular Cell Biology. 15, 8, p. 536-50 15 p.Research output: Contribution to journal › Review › Research › peer-review
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Sequencing of the First Draft of the Human Acetylome
Choudhary, Chuna Ram & Mann, Matthias, 2020, In : Clinical Chemistry. 66, 6, p. 852-853 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic exploration of lysine acetylation signaling
Choudhary, Chuna Ram, 2019, In : Molecular & Cellular Proteomics. 18, 8, p. S25 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells
Ding, L., Paszkowski-Rogacz, M., Winzi, M., Chakraborty, D., Theis, M., Singh, S., Ciotta, G., Poser, I., Roguev, A., Chu, W. K., Choudhary, Chuna Ram, Mann, Matthias, Stewart, A. F., Krogan, N. & Buchholz, F., 26 Aug 2015, In : Cell Systems. 1, 2, p. 141-151 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling
Fiil, Berthe Katrine, Damgaard, R. B., Wagner, S. A., Keusekotten, K., Fritsch, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chuna Ram, Komander, D. & Gyrd-Hansen, Mads, 27 Jun 2013, In : Molecular Cell. 50, 6, p. 818-30 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage
Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B. T., Passmore, L. A., Patel, K. J., Olsen, Jesper Velgaard, Choudhary, Chuna Ram, Bekker-Jensen, Simon Holst & Mailand, Niels, Jan 2015, In : Molecular Cell. 57, 1, p. 150-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Predicting post-translational lysine acetylation using support vector machines
Gnad, F., Ren, S., Choudhary, Chuna Ram, Cox, J. & Mann, M., 1 Jul 2010, In : Bioinformatics. 26, 13, p. 1666-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Gupta, R., Somyajit, K., Narita, Takeo, Maskey, E., Stanlie, A., Kremer, M., Typas, Dimitris, Lammers, M., Mailand, Niels, Nussenzweig, A., Lukas, Jiri & Choudhary, Chuna Ram, 2018, In : Cell. 173, 4, p. 972-988Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation
Hansen, B. K., Gupta, R., Baldus, L., Lyon, D., Narita, Takeo, Lammers, M., Choudhary, Chuna Ram & Weinert, B. T., 2019, In : Nature Communications. 10, 11 p., 1055.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae
Henriksen, P., Wagner, S. A., Weinert, B. T., Sharma, S., Bacinskaja, G., Rehman, M., Juffer, A. H., Walther, T. C., Lisby, Michael & Choudhary, Chuna Ram, 2012, In : Molecular & Cellular Proteomics. 11, 11, p. 1510-1522 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Convergence of Ubiquitylation and Phosphorylation Signaling in Rapamycin-Treated Yeast Cells
Iesmantavicius, V., Weinert, B. T. & Choudhary, Chuna Ram, 24 Jun 2014, In : Molecular & Cellular Proteomics. 13, 8, p. 1979-92 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β
J D'Souza, R. C., Knittle, A. M., Nagaraj, N., van Dinther, M., Choudhary, Chuna Ram, Ten Dijke, P., Mann, Matthias & Sharma, K., Jul 2014, In : Science signaling. 7, 335, p. rs5 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry
Jungmichel, S., Sylvestersen, K. B., Choudhary, Chuna Ram, Nguyen, S., Mann, Matthias & Nielsen, Michael Lund, 13 Feb 2014, In : Cell Reports. 6, 3, p. 578-91 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation
Khoa, L. T. P., Tsan, Y., Mao, F., Kremer, D. M., Sajjakulnukit, P., Zhang, L., Zhou, B., Tong, X., Bhanu, N. V., Choudhary, Chuna Ram, Garcia, B. A., Yin, L., Smith, G. D., Saunders, T. L., Bielas, S. L., Lyssiotis, C. A. & Dou, Y., 2020, In : Cell Stem Cell. 27, 3, p. 441-458.e10 29 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13781159
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Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
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Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover
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Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance
Research output: Contribution to journal › Journal article › Research › peer-review
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