René Villadsen

René Villadsen

Associate Professor


Publication year:
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1 - 42 out of 42Page size: 500
  1. 2024
  2. Published

    Evidence of steady-state fibroblast subtypes in the normal human breast as cells-of-origin for perturbed-state fibroblasts in breast cancer

    Bagger, M. M., Sjölund, J., Kim, Jiyoung, Kohler, Katharina Theresa, Villadsen, René, Jafari Kermani, Abbas, Kassem, Moustapha Saad El-Deen, Pietras, K., Rønnov-Jessen, Lone & Petersen, Ole William, 2024, In: Breast Cancer Research. 26, 1, 19 p., 11.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2023
  4. Published

    SSEA-1 Correlates With the Invasive Phenotype in Breast Cancer

    Kohler, Katharina Theresa, Møller Hansen, A. A., Kim, Jiyoung & Villadsen, René, 2023, In: Journal of Histochemistry and Cytochemistry. 71, 8, 221554231189312.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2022
  6. Published

    Ductal keratin 15+ luminal progenitors in normal breast exhibit a basal-like breast cancer transcriptomic signature

    Kohler, Katharina Theresa, Goldhammer, N., Demharter, S., Pfisterer, U., Khodosevich, Konstantin, Rønnov-Jessen, Lone, Petersen, Ole William, Villadsen, René & Kim, Jiyoung, 2022, In: npj Breast Cancer. 8, 1, 12 p., 81.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Myoepithelial progenitors as founder cells of hyperplastic human breast lesions upon PIK3CA transformation

    Goldhammer, N., Kim, Jiyoung, Villadsen, René, Rønnov-Jessen, Lone & Petersen, Ole William, 2022, In: Communications Biology . 5, 1, 13 p., 219.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus

    Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Villadsen, René & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 19 p., 44.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2021
  10. Published

    Desensitization of human breast progenitors by a transient exposure to pregnancy levels of estrogen

    Rønnov-Jessen, Lone, Kim, Jiyoung, Goldhammer, N., Klitgaard, M. C., Smicius, M., Bechmann, M. B., Villadsen, René & Petersen, Ole William, 2021, In: Scientific Reports. 11, 7 p., 17232.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2020
  12. Published

    AXL Is a Driver of Stemness in Normal Mammary Gland and Breast Cancer

    Engelsen, A. S. T., Wnuk-Lipinska, K., Bougnaud, S., Pelissier Vatter, F. A., Tiron, C., Villadsen, R., Miyano, M., Lotsberg, M. L., Madeleine, N., Panahandeh, P., Dhakal, S., Tan, T. Z., Peters, S. D. M., Grøndal, S., Aziz, S. M., Nord, S., Herfindal, L., Stampfer, M. R., Sørlie, T., Brekken, R. A. & 8 others, Straume, O., Halberg, N., Gausdal, G., Thiery, J. P., Akslen, L. A., Petersen, Ole William, LaBarge, M. A. & Lorens, J. B., 2020, In: iScience. 23, 11, 40 p., 101649.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Fibroblasts direct differentiation of human breast epithelial progenitors

    Morsing, M., Kim, Jiyoung, Villadsen, René, Goldhammer, N., Jafari Kermani, Abbas, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2020, In: Breast Cancer Research. 22, 16 p., 102.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Genesers Histologi

    Brüel, A., Christensen, E. I., Eld, M., Prætorius, J., Qvortrup, Klaus, Tranum-Jensen, Jørgen, Villadsen, René & Geneser, F., 2020, 2 ed. Danmark: Munksgaard . 741 p.

    Research output: Book/Report › Book › Education

  15. Published

    Heterogeneity of CEACAM5 in breast cancer

    Bechmann, M. B., Brydholm, A. V., Codony, V. L., Kim, Jiyoung & Villadsen, René, 2020, In: OncoTarget. 11, 43, p. 3886-3899 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The Expression Pattern of Epidermal Differentiation Marker Keratin 10 in the Normal Human Breast and Breast Cancer Cells

    Kim, Jiyoung & Villadsen, René, 2020, In: Journal of Histochemistry and Cytochemistry. 68, 8, p. 561-570

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2019
  18. Published

    A CD146 FACS Protocol Enriches for Luminal Keratin 14/19 Double Positive Human Breast Progenitors

    Ísberg, Ó. G., Kim, Jiyoung, Fridriksdottir, A. J., Morsing, M., Timmermans-Wielenga, V., Rønnov-Jessen, Lone, Petersen, Ole William & Villadsen, René, 2019, In: Scientific Reports. 9, 11 p., 14843.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2018
  20. Published

    Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland

    Kim, Jiyoung & Villadsen, René, Dec 2018, In: Journal of Histochemistry and Cytochemistry. 66, 12, p. 879-888 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

    Bagger, Sofie Morsing, Hopkinson, B. M., Pandey, D. P., Bak, M., Brydholm, A. V., Villadsen, René, Helin, K., Rønnov-Jessen, Lone, Petersen, Ole William & Kim, Jiyoung, 2018, In: Molecular Cancer. 17, 1, p. 1-6 6 p., 171.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  22. Published

    Warburg Effect Metabolism Drives Neoplasia in a Drosophila Genetic Model of Epithelial Cancer

    Eichenlaub, T., Villadsen, René, Freitas, F. C. P., Andrejeva, Diana, Aldana, Blanca, Nguyen, H. T., Petersen, Ole William, Gorodkin, Jan, Herranz, Hector & Cohen, S. M., 2018, In: Current Biology. 28, 20, p. 3220-3228.e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. 2017
  24. Published

    Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype

    Hopkinson, B. M., Klitgaard, M. C., Petersen, Ole William, Villadsen, René, Rønnov-Jessen, Lone & Kim, Jiyoung, 7 Feb 2017, In: OncoTarget. 8, 6, p. 10580-10593 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Proof of region-specific multipotent progenitors in human breast epithelia

    Fridriksdottir, A. J., Villadsen, René, Morsing, M., Klitgaard, M. C., Kim, Jiyoung, Petersen, Ole William & Rønnov-Jessen, Lone, 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 47, p. E10102–E10111

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. 2016
  27. Published

    Evidence of two distinct functionally specialized fibroblast lineages in breast stroma

    Morsing, M., Klitgaard, M. C., Jafari Kermani, Abbas, Villadsen, René, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2016, In: Breast Cancer Research (Online). 18, 11 p., 108.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. 2015
  29. Published

    Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture

    Fridriksdóttir, A. J. R., Kim, Jiyoung, Villadsen, René, Klitgaard, M. C., Hopkinson, B. M., Petersen, Ole William & Rønnov-Jessen, Lone, 2015, In: Nature Communications. 6, 12 p., 8786.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2014
  31. Published

    A Marker of Endocrine Receptor-Positive Cells, CEACAM6, Is Shared by Two Major Classes of Breast Cancer: Luminal and HER2-Enriched

    Balk-Møller, E., Kim, Jiyoung, Hopkinson, B., Timmermans-Wielenga, V., Petersen, Ole William & Villadsen, René, Apr 2014, In: American Journal of Pathology. 184, 4, p. 1198-1208 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. 2012
  33. Published

    Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia

    Garbe, J. C., Pepin, F., Pelissier, F. A., Sputova, K., Fridriksdottir, A. J., Guo, D. E., Villadsen, René, Park, M., Petersen, Ole William, Borowsky, A. D., Stampfer, M. R. & Labarge, M. A., Jul 2012, In: Cancer Research. 72, 14, p. 3687-701 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Hypoxic conditions induce a cancer-like phenotype in human breast epithelial cells

    Vaapil, M., Helczynska, K., Villadsen, René, Petersen, Ole William, Johansson, E., Beckman, S., Larsson, C., Påhlman, S. & Jögi, A., 2012, In: P L o S One. 7, 9, p. e46543

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity

    Kim, Jiyoung, Villadsen, René, Sørlie, T., Fogh, L., Grønlund, S. Z., Fridriksdóttir, A. J. R., Kuhn, I., Rank, F., Wielenga, V. T., Solvang, H., Edwards, P. A. W., Børresen-Dale, A., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, Ole William, 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 16, p. 6124-6129 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. 2011
  37. Published

    Endothelial induced EMT in breast epithelial cells with stem cell properties

    Sigurdsson, V., Hilmarsdottir, B., Sigmundsdottir, H., Fridriksdottir, A. J. R., Ringnér, M., Villadsen, René, Borg, A., Agnarsson, B. A., Petersen, Ole William, Magnusson, M. K. & Gudjonsson, T., 2011, In: P L o S One. 6, 9, p. e23833

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. 2010
  39. Published

    Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment

    De Neergaard, M., Kim, Jiyoung, Villadsen, René, Fridriksdóttir, A. J. R., Rank, F., Timmermans-Wielenga, V., Langerød, A., Børresen-Dale, A., Petersen, Ole William & Rønnov-Jessen, Lone, 2010, In: American Journal of Pathology. 176, 3, p. 1229-1240 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. 2009
  41. Published

    Human mammary progenitor cell fate decisions are productsof interactions with combinatorial microenvironments

    LaBarge, M. A., Nelson, C. M., Villadsen, René, Rubner Fridriksdottir, A. J., Ruth, J. R., Stampfer, M. R., Petersen, Ole William & Bissell, M. J., 2009, In: Integrative Biology. 1, p. 70-79 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. 2008
  43. Published

    Dissection of a stem cell hierarchy in the human breast

    Rubner Fridriksdottir, A. J., Villadsen, René, Kim, Jiyoung, Rønnov-Jessen, Lone & Petersen, Ole William, 2008, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. p. 412 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  44. 2007
  45. Published

    Evidence for a stem cell hierarchy in the adult human breast

    Villadsen, René, Fridriksdottir, A. J., Rønnov-Jessen, Lone, Gudjonsson, T., Rank, F., LaBarge, M. A., Bissell, M. J. & Petersen, Ole William, 2007, In: Journal of Cell Biology. 177, 1, p. 87-101 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. 2005
  47. Published

    In search of a stem cell hierarchy in the human breast and its relevance to breast cancer evolution

    Villadsen, René, Nov 2005, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 113, 11-12, p. 903-21 19 p.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Annexin A8 Is Up-Regulated During Mouse Mammary Gland Involution and Predicts Poor Survival in Breast Cancer

    Stein, T., Price, K. N., Morris, J. S., Heath, V. J., Ferrier, R. K., Bell, A. K., Pringle, M., Villadsen, René, Petersen, Ole William, Sauter, G., Bryson, G., Mallon, E. A. & Gusterson, B. A., 2005, In: Clinical Cancer Research. 11, p. 6872-6879

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Maintenance of Cell Type Diversification in the Human Breast

    Rubner Fridriksdottir, A. J., Villadsen, René, Gudjonsson, T. & Petersen, Ole William, 2005, In: Journal of Mammary Gland Biology and Neoplasia. 10, 1, p. 61-74

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. 2004
  51. Published

    Collagen gel contraction serves to rapidly distinguish epithelial- and mesenchymal-derived cells irrespective of alpha-smooth muscle actin expression

    Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Petersen, Ole William, 2004, In: In Vitro Cellular & Developmental Biology - Animal. 39, 7, p. 297-303 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Immortalization protocols used in cell culture models of human breast morphogenesis

    Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Petersen, O. W., 2004, In: Cellular and molecular life sciences : CMLS. 61, 19-20, p. 2523-34 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. 2003
  54. Published

    Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia

    Petersen, Ole William, Gudjonsson, T., Villadsen, René, Bissell, M. J. & Rønnov-Jessen, Lone, 2003, In: Cell Proliferation. 36 Suppl 1, p. 33-44 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Epithelial to Mesenchymal Transition in Human Breast Cancer Can Provide a Nonmalignant Stroma

    Petersen, Ole William, Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rank, F. E., Niebuhr, E., Bisell, M. J. & Rønnov-Jessen, Lone, 2003, In: American Journal og Pathology. Vol. 162, p. 391-402

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    To create the correct microenvironment: Three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia

    Gudjonsson, T., Rønnov-Jessen, Lone, Villadsen, René, Bissell, M. J. & Petersen, Ole William, 2003, In: Methods. Vol. 30, p. 247-255

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. 2002
  58. Published

    Differential expression of a chloride intracellular channel gene, CLIC4, in transforming growth factor-β1-mediated conversion of fibroblasts to myofibroblasts

    Rønnov-Jessen, Lone, Villadsen, René, Edwards, J. C. & Petersen, Ole William, 2002, In: American Journal of Pathology. 161, 2, p. 471-480 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Identification of EPSTI1, a novel gene induced by epithelial-stromal interaction in human breast cancer

    Nielsen, H. L., Rønnov-Jessen, Lone, Villadsen, René & Petersen, Ole William, 2002, In: Genomics. 79, 5, p. 703-10 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties

    Gudjonsson, T., Villadsen, René, Nielsen, H. L., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, Ole William, 2002, In: Genes Dev. vol. 16(6), p. 693-706

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition

    Gudjonsson, T., Rønnov-Jessen, Lone, Villadsen, René, Rank, F. E., Bissell, M. J. & Petersen, Ole William, 2002, In: Journal of Cell Science. 115, p. 39-50

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. 2001
  63. Published

    The plasticity of human breast carcinoma cells is more than epithelial to mesenchymal conversion

    Petersen, Ole William, Nielsen, H. L., Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Bissell, M. J., 2001, In: Breast Cancer Research (Online Edition). 3, p. 213-217

    Research output: Contribution to journal › Review › Research

  64. 2000
  65. Published

    Complete loss of wild-type TP53 in a nontransformed human epithelial cell line is preceded by a phase during which a heterozygous TP53 mutant effectively outgrows the homozygous wild-type cells

    Villadsen, René, Nielsen, K. V., Bolund, L. & Briand, P., 1 Jan 2000, In: Cancer Genetics and Cytogenetics. 116, 1, p. 28-34 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

ID: 4354