Sten Madsbad

Sten Madsbad

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


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  1. Published

    Ætiologi og patogenese, type 2 diabetes

    Madsbad, Sten, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johansen, K. & Christiansen, J. S. (eds.). Munksgaard , p. 97-107

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  2. Published

    Young, low-birth-weight men are not more susceptible to the diabetogenic effects of a prolonged free fatty acid exposure than matched controls.

    Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, Flemming, Madsbad, Sten & Vaag, Allan, 2005, In: Metabolism - Clinical and Experimental. 54, 10, p. 1398-406 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    What is Diabetes Remission?

    Holst, Jens Juul & Madsbad, Sten, 2021, In: Diabetes Therapy. 12, p. 641-646 6 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  4. Published

    Weight loss maintenance with exercise and liraglutide improves glucose tolerance, glucagon response, and beta cell function

    Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Lundgren, J. R., Martinussen, C., Wiingaard, C., Knudsen, C., Frikke-Schmidt, Ruth, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Obesity. 31, 4, p. 977-989 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Weight-loss induced by carbohydrate restriction does not negatively affect health-related quality of life and cognition in people with type 2 diabetes: A randomised controlled trial

    Jensen, N. J., Wodschow, H. Z., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Haugaard, Steen Bendix, Krarup, T., Rungby, Jørgen & Thomsen, M. N., 2022, In: Clinical Nutrition. 41, 7, p. 1605-1612 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Weight loss-induced improvements of endothelial function and cardiovascular risk factors are maintained with exercise, liraglutide or the combination

    Lundgren, J. R., Bladbjerg, E. M., Janus, C., Gliemann, Lasse, Olsen, L. M., Juhl, C. R., Jensen, Simon Birk Kjær, Thirumathyam, R., Stallknecht, Bente Merete, Holst, Jens Juul, Hove, Jens Dahlgaard, Madsbad, Sten, Antoinades, C. & Torekov, Signe Sørensen, 2020, In: Diabetologia. 63, SUPPL 1, p. S457-S457 1 p., 959.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  7. Published

    Weight loss improves β-cell function independently of dietary carbohydrate restriction in people with type 2 diabetes: A 6-week randomized controlled trial

    Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Fenger, M., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2022, In: Frontiers in Nutrition. 9, 14 p., 933118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels

    pjx571, pjx571, Iepsen, E. P. W., Galijatovic, E. A. A., Mahendran, Y., Lundgren, J. R., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, Dec 2016, In: Metabolomics. 12, 12, p. 1-9 9 p., 181.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Variable reliability of surrogate measures of insulin sensitivity after Roux-en-Y gastric bypass

    Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Jørgensen, N. B., Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 5, p. R797-R805 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Validation of methods for measurement of insulin secretion in humans in vivo.

    Kjems, L. L., Christiansen, E., Vølund, A., Bergman, R. N. & Madsbad, Sten, 2000, In: Diabetes. 49, 4, p. 580-588 9 p.

    Research output: Contribution to journal › Journal article › Research

  11. Published

    Updates in weight loss surgery and gastrointestinal peptides

    Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten & Holst, Jens Juul, Feb 2015, In: Current Opinion in Endocrinology, Diabetes and Obesity. 22, 1, p. 21-8 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    Unprecedented high insulin secretion in a healthy human subject after intravenous glucagon-like peptide-1: a case report

    Knop, Filip Krag, Lund, Asger Bach, Madsbad, Sten, Holst, Jens Juul, Krarup, T. & Vilsbøll, T., 2014, In: BMC Research Notes. 7, p. 1-6 6 p., 326.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Under-reporting of adverse effects of tesofensine

    Astrup, A., Madsbad, Sten, Breum, Leif, Jensen, T. J., Kroustrup, J. P. & Larsen, T. M., 2013, In: Lancet. 382, 9887, p. 127 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  14. Published

    Udfordringer for perioperativ glykæmisk kontrol hos patienter med diabetes

    Madsbad, Sten, Wiberg, M., Issa, L. M., Schmidt, S. & Kehlet, Henrik, 17 Oct 2022, In: Ugeskrift for Laeger. 184, 42, 9 p., V05220321.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Type 2-diabetes--et sammenhængende sundhedsvæsen efterlyses

    Madsbad, Sten, 2012, In: Ugeskrift for Laeger. 174, 37, p. 2131

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Type 2 diabetes: which drug as add-on to metformin?

    Madsbad, Sten, 2012, In: Lancet. 379, 9833, p. 2222-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Twelve-Week Treatment With Liraglutide as Add-on to Insulin in Normal-Weight Patients With Poorly Controlled Type 1 Diabetes: A Randomized, Placebo-Controlled, Double-Blind Parallel Study

    Frandsen, C. S., Dejgaard, T. F., Holst, Jens Juul, Andersen, H. U., Thorsteinsson, B. & Madsbad, Sten, Dec 2015, In: Diabetes Care. 38, 12, p. 2250-7 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial

    Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748

    Research output: Contribution to journal › Conference abstract in journal › Research

  20. Published

    Tumor necrosis factor alpha is associated with insulin-mediated suppression of free fatty acids and net lipid oxidation in HIV-infected patients with lipodystrophy

    Haugaard, S. B., Andersen, Ove, Pedersen, S., Dela, Flemming, Fenger, M., Richelsen, B., Madsbad, Sten, Iversen, J. & Pedersen, E. S., 2006, In: Metabolism - Clinical and Experimental. 55, 2, p. 175-82 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB

    pjx571, pjx571, Lundgren, Jens, Albrechtsen, Nicolai Jacob Wewer, Mahendran, Y., Iepsen, E. P. W., Finocchietto, P., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Obesity Science & Practice. 3, 4, p. 425-433 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss

    Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J., Pedersen, Oluf Borbye, Hansen, Torben, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2015, In: International journal of obesity (2005). 39, 5, p. 834-41 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Treatment with GLP-1 Receptor Agonists

    Madsbad, Sten & Holst, Jens Juul, 2018, Diabetes: Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment. Bonora, E. & DeFronzo, R. (eds.). Springer, 45 p. (Endocrinology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  24. Published

    Treatment potential of the GLP-1 receptor agonists in type 2 diabetes mellitus: a review

    Østergaard, L., Frandsen, C. S. & Madsbad, Sten, 2016, In: Expert Review of Clinical Pharmacology. 9, 2, p. 241-65 25 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Treatment of type 2 diabetes with incretin-based therapies

    Madsbad, Sten, 2008, In: Lancet. 373, 9662, p. 438-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists

    Kielgast, U., Holst, Jens Juul & Madsbad, Sten, Nov 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists

    Kielgast, U., Holst, J., Madsbad, Sten, Kielgast, U., Holst, J. J. & Madsbad, Sten, 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The role of glucagon-like peptide-1 impairment in obesity and potential therapeutic implications

    Madsbad, Sten, Jan 2014, In: Diabetes, Obesity and Metabolism. 16, 1, p. 9-21 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    The role of empagliflozin-induced metabolic changes for cardiac function in patients with type 2 diabetes. A randomized cross-over magnetic resonance imaging study with insulin as comparator

    Thirumathyam, R., Richter, Erik A., van Hall, Gerrit, Holst, Jens Juul, Fenger, M., Goetze, Jens P. , Dixen, Ulrik, Vejlstrup, N., Madsbad, Sten, Madsen, Per & Jørgensen, N. B., 2024, In: Cardiovascular Diabetology. 23, 1, p. 1-13 13.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    The role of GLP-1 in postprandial glucose metabolism after bariatric surgery: a narrative review of human GLP-1 receptor antagonist studies

    Hindsø, M., Svane, M. S., Hedbäck, N., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2021, In: Surgery for Obesity and Related Diseases. 17, 7, p. 1383-1391

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    The proposed terminology 'A(1c)-derived average glucose' is inherently imprecise and should not be adopted. Reply to Bloomgarden ZT, Inzucchi SE, Karnieli E, et al. [letter]

    Haugaard, S. B., Madsbad, Sten & Mølvig, J., 2008, In: Diabetologia. 52, 3, p. 547-49

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The prevalence of metabolic syndrome in Danish patients with HIV infection: the effect of antiretroviral therapy

    Hansen, B. R., Petersen, J., Haugaard, Steen Bendix, Madsbad, Sten, Obel, Niels, Suzuki, Y., Andersen, O., Hansen, B. R., Petersen, J., Haugaard, S. B., Madsbad, Sten, Obel, N., Suzuki, Y. & Andersen, Ove, 2009, In: HIV Medicine. 10, 6, p. 378-87 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The prevalence of comorbidities in Danish patients with obesity – A Danish register-based study based on data from 2002 to 2018

    Pedersen, M. H., Bøgelund, M., Dirksen, Carsten Moro, Johansen, P., Jørgensen, Nils Bruun, Madsbad, Sten & Pantin, U. H., 2022, In: Clinical obesity. 12, 5, e12542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The pathophysiology of diabetes involves a defective amplification of the late-phase insulin response to glucose by glucose-dependent insulinotropic polypeptide-regardless of etiology and phenotype

    Vilsbøll, Tina, Knop, Filip Krag, Krarup, T., Johansen, A., Madsbad, Sten, Larsen, S., Hansen, T., Pedersen, O., Holst, J. M. & Johansen, A., 1 Oct 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 10, p. 4897-903 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose leves in patients with type 2 diabetes.

    Zander, M., Madsbad, Sten, Deacon, C. & Holst, J., 2006, In: Diabetologia. 49, p. 369-374 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

    Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    The long-term effect of tesofensine on weight loss: interim results from a one-armed, open-labelled extension study

    Sjödin, Anders Mikael, Madsbad, Sten, Breum, Leif, Kroustrup, J. P., Raben, Anne, Jensen, J. K. S., Meier, D. & Astrup, A., 2009, In: Obesity. 17, Suppl. 2, p. S107 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  38. Published

    The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.

    Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2007, In: Regulatory Peptides. 144, 1-3, p. 123-30 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The insulin-resistant phenotype of polycystic ovary syndrome

    Svendsen, P. F., Madsbad, Sten & Nilas, L., 2009, In: Fertility and Sterility. 94, 3, p. 1052-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects.

    Kjems, L. L., Holst, J. J., Vølund, A. & Madsbad, Sten, 2003, In: Diabetes. 52, 2, p. 380-386 7 p.

    Research output: Contribution to journal › Journal article › Research

  41. Published

    The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

    Kjems, L. L., Holst, Jens Juul, Vølund, A. & Madsbad, Sten, Feb 2003, In: Diabetes. 52, 2, p. 380-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

    Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The impact of gastric bypass surgery on sex hormones and menstrual cycles in premenopausal women

    Kjær, M. M., Madsbad, Sten, Hougaard, D. M., Cohen, A. S. & Nilas, L., 2017, In: Gynecological Endocrinology. 33, 2, p. 160-163 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The immune marker soluble urokinase plasminogen activator receptor is associated with new-onset diabetes in non-smoking women and men

    Haugaard, S. B., Andersen, Ove, Hansen, T. W., Eugen-Olsen, J., Linneberg, Allan René, Madsbad, Sten, Olsen, M. H., Jørgensen, T., Borch-Johnsen, K. & Jeppesen, J., 2012, In: Diabetic Medicine. 29, 4, p. 479-487

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The exaggerated glucagon-like peptide-1 response is important for the improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes

    Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Jacobsen, S. H., Worm, Dorte, Hansen, D. L., Kristiansen, V. B., Naver, L., Madsbad, Sten & Holst, Jens Juul, 6 May 2013, In: Diabetes. 62, 9, p. 3044-3052 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.

    Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The effects of postprandial exercise and meal glycemic index on plasma glucose and glucoregulatory hormone responses after Roux-en-Y gastric bypass

    Ternhamar, T., Møller, A., Martinussen, C., Svane, M. S., Hindsø, M., Jørgensen, N. B., Dirksen, C., Jensen, Jens-Erik Beck, Hartmann, Bolette, Holst, Jens Juul, Kiens, Bente, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: American journal of physiology. Endocrinology and metabolism. 325, 5, p. E540-E551 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    The effect of the deterioration of insulin sensitivity on beta-cell function in growth-hormone-deficient adults following 4-month growth hormone replacement therapy.

    Rosenfalck, A. M., Fisker, S., Hilsted, J., Dinesen, B., Vølund, A., Jørgensen, J. O., Christiansen, J. S. & Madsbad, Sten, 1999, In: Growth Hormone & IGF Research. 9, 2, p. 96-105 10 p.

    Research output: Contribution to journal › Journal article › Research

  49. Published

    The effect of tesofensine on weight loss: results from a one-armed, open-labelled extension study

    Astrup, A., Madsbad, Sten, Breum, Leif, Kroustrup, J. P., Raben, A., Jensen, J. K. S., Meier, D. & Sjödin, Anders Mikael, 2009, In: Obesity Facts. suppl. 2, p. 211-212 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  50. Published

    The effect of metformin versus placebo in combination with insulin analogues on bone mineral density and trabecular bone score in patients with type 2 diabetes mellitus: a randomized placebo-controlled trial

    Nordklint, A. K., Almdal, Thomas Peter, Vestergaard, P., Lundby-Christensen, L., Boesgaard, T. W., Breum, Leif, Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Jensen, T., Krarup, T., Madsbad, Sten, Mathiesen, Elisabeth, Perrild, Hans, Tarnow, L., Thorsteinsson, B., drb459, drb459, Lund, S. S. & Eiken, P., 2018, In: Osteoporosis International. 29, 11, p. 2517-2526

    Research output: Contribution to journal › Journal article › Research › peer-review

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