Kristoffer Lihme Egerod
Research consultant
Pers Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal, 2200 København N.
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ß-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced Hyperglycemia
Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Wierup, N., Sundler, F., Holst, Birgitte & Schwartz, Thue W., 2011, In: International Journal of Endocrinology. 2011, p. 401258Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission
Bentsen, M. A., Rausch, D. M., Mirzadeh, Z., Muta, K., Scarlett, J. M., Brown, J. M., Herranz-Pérez, V., Baquero, A. F., Thompson, J., Alonge, K. M., Faber, C. L., Kaiyala, K. J., Bennett, C., Pyke, C., Ratner, C., Egerod, K. L., Holst, B., Meek, T. H., Kutlu, B., Zhang, Y. & 9 others, , 2020, In: Nature Communications. 11, 1, 4458.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells
Egerod, Kristoffer Lihme, Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Zhao, M., Barir-Jensen, D., Nygaard, E. B., Petersen, N., Holst, Jens Juul & Schwartz, Thue W., Nov 2015, In: Endocrinology. 156, 11, p. 3909-23 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The aromatic amino acid sensor GPR142 controls metabolism through balanced regulation of pancreatic and gut hormones
Rudenko, Olga, Shang, J., Munk, A., Ekberg, J. P., Petersen, N., Engelstoft, M. S., Egerod, Kristoffer Lihme, Hjorth, Siv Annegrethe, Wu, M., Feng, Y., Zhou, Y., Mokrosinski, J., Thams, P., Reimann, F., Gribble, F., Rehfeld, Jens Frederik, Holst, Jens Juul, Treebak, Jonas Thue, Howard, A. D. & Schwartz, Thue W., 2019, In: Molecular Metabolism. 19, p. 49-64 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration
Cornelia Peeters, M., Fokkelman, M., Boogaard, B., Egerod, Kristoffer Lihme, van de Water, B., IJzerman, A. P. & Schwartz, Thue W., Dec 2015, In: Cellular Signalling. 27, 12, p. 2579-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Molecular Diversity of Vagal Afferents Revealed
Egerod, Kristoffer Lihme, Schwartz, Thue W. & Gautron, L., 2019, In: Trends in Neurosciences. 42, 10, p. 663-666Research output: Contribution to journal › Editorial › Research › peer-review
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The MicroRNA Repertoire in Enteroendocrine Cells: Identification of miR-375 as a Potential Regulator of the Enteroendocrine Lineage
Knudsen, L. A., Petersen, N., Schwartz, Thue W. & Egerod, Kristoffer Lihme, Nov 2015, In: Endocrinology. 156, 11, p. 3971-83 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus
Jørgensen, Astrid Sissel, Brandum, E. P., Mikkelsen, J. M., Orfin, K. A., Boilesen, D. R., Egerod, Kristoffer Lihme, Moussouras, N. A., Vilhardt, Frederik, Kalinski, P., Basse, P., Chen, Yen-Hsi, Yang, Zhang, Dwinell, M. B., Volkman, B. F., Veldkamp, C. T., Holst, Peter Johannes, Lahl, K., Goth, C. K., Rosenkilde, Mette & Hjortø, Gertrud Malene, 2021, In: Cellular and Molecular Life Sciences. 78, p. 6963-6978 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single-Cell Mapping of GLP-1 and GIP Receptor Expression in the Dorsal Vagal Complex
Ludwig, M. Q., Todorov, Petar Vladimirov, Egerod, Kristoffer Lihme, Olson, D. P. & Pers, Tune H, 2021, In: Diabetes. 70, 9, p. 1945-1955 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells
Engelstoft, M. S., Park, W-M., Sakata, I., Kristensen, L. V., Husted, A. S., Osborne-Lawrence, S., Piper, P. K., Walker, A. K., Pedersen, M. H., Nøhr, M. K., Pan, J., Sinz, C. J., Carrington, P. E., Akiyama, T. E., Jones, R. M., Tang, C., Ahmed, K., Offermanns, S., Egerod, K. L., Zigman, J. M. & 1 others, , Nov 2013, In: Molecular Metabolism. 2, 4, p. 376-92 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Risperidone treatment increases CB1 receptor binding in rat brain
Secher, A., Husum, H., Holst, Birgitte, Egerod, Kristoffer Lihme & Mellerup, Erling Thyge, 2010, In: Neuroendocrinology. 91, 2, p. 155-68 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones
Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.Research output: Contribution to journal › Conference article › Research › peer-review
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Research Resource: A Chromogranin A Reporter for Serotonin and Histamine Secreting Enteroendocrine Cells
Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Egerod, Kristoffer Lihme, Osborne-Lawrence, S., Poulsen, Steen Seier, Zigman, J. M. & Schwartz, Thue W., Nov 2015, In: Molecular endocrinology (Baltimore, Md.). 29, 11, p. 1658-71 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.Research output: Contribution to journal › Journal article › Research › peer-review
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Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms
Egerod, Kristoffer Lihme, Petersen, N., Timshel, P. N., Rekling, Jens Christian, Wang, Y., Liu, Q., Schwartz, Thue W. & Gautron, L., 2018, In: Molecular Metabolism. 12, p. 62-75 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmin-driven fibrinolysis facilitates skin tumor growth in a gender-dependent manner
Hald, A., Eickhardt, H., Maerkedahl, R. B., Feldborg, C. W., Egerod, Kristoffer Lihme, Engelholm, Lars Henning, Laerum, O. D., Lund, L. R. & Rønø, B., Nov 2012, In: F A S E B Journal. 26, 11, p. 4445-4457 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neurotensin Is Co-Expressed, Co-Released And Acts Together With Glp-1 And Pyy In Enteroendocrine Control Of Metabolism
Grunddal, Kaare Villum, Ratner, C. F., Svendsen, B., Sommer, F., Engelstoft, M. S., Madsen, A. N., Pedersen, Jens, Nøhr, M. K., Egerod, Kristoffer Lihme, Nawrocki, A. R., Kowalski, T., Howard, A. D., Poulsen, Steen Seier, Offermanns, S., Bäckhed, G. F., Holst, Jens Juul, Holst, Birgitte & Schwartz, Thue W., Jan 2016, In: Endocrinology. 157, 1, p. 176-94 19 p., en20151600.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular identification of the first insect proctolin receptor.
Egerod, Kristoffer Lihme, Reynisson, E., Hauser, Frank, Williamson, M., Cazzamali, G. & Grimmelikhuijzen, Cornelis (Cok), 2003, In: Biochemical and Biophysical Research Communications. 306, 2, p. 437-42 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular consequences of peripheral Influenza A infection on cell populations in the murine hypothalamus
Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, In: eLife. 12, 28 p., RP87515.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular cloning and functional expression of the first two specific insect myosuppressin receptors.
Egerod, Kristoffer Lihme, Reynisson, E., Hauser, Frank, Cazzamali, G., Williamson, M. & Grimmelikhuijzen, Cornelis (Cok), 2003, In: Proceedings of the National Academy of Science of the United States of America. 100, 17, p. 9808-13 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular Consequences of Peripheral Influenza A Infection on Cell Populations in the Murine Hypothalamus
Lemcke, René, Jensen, Christine Egebjerg, Pagh-Berendtsen, Nicolai, Egerod, Kristoffer Lihme, Thomsen, Allan Randrup, Pers, Tune H, Christensen, Jan Pravsgaard & Kornum, Birgitte Rahbek, 2023, 31 p.Research output: Working paper › Preprint › Research
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Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient
Rifes, P., Isaksson, M., Rathore, Gaurav Singh, Aldrin-Kirk, P., Moller, O. K., Barzaghi, G., Lee, J., Egerod, Kristoffer Lihme, Belmont-Rausch, Dylan Matthew, Parmar, M., Pers, Tune H, Laurell, T. & Kirkeby, Agnete, 2020, In: Nature Biotechnology. 38, p. 1265-1273 9 p.Research output: Contribution to journal › Letter › Research › peer-review
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Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions.
Frimurer, Thomas Michael, Mende, F., Graae, A., Engelstoft, M. S., Egerod, Kristoffer Lihme, Nygaard, R., Gerlach, L., Hansen, J. B., Schwartz, Thue W. & Holst, Birgitte, 2017, In: Journal of Medicinal Chemistry. 60, 3, p. 886-898 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microbial fermentation of flaxseed fibers modulates the transcriptome of GPR41-expressing enteroendocrine cells and protects mice against diet-induced obesity
Arora, Tulika, Rudenko, Olga, Egerod, Kristoffer Lihme, Husted, Anna Sofie, Kovatcheva-Datchary, P., Akrami, R., Kristensen, M., Schwartz, Thue W. & Backhed, F., Mar 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 3, p. E453-E463Research output: Contribution to journal › Journal article › Research › peer-review
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MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans
Andersson, E. A., Holst, Birgitte, Sparsø, T., Grarup, Niels, Banasik, Karina, Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Egerod, Kristoffer Lihme, Lauritzen, T., Sørensen, Thorkild I.A., Bonnefond, A., Meyre, D., Froguel, P., Schwartz, Thue W., Pedersen, Oluf Borbye & Hansen, Torben, 2010, In: Diabetes. 59, 6, p. 1539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 3417
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L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
378
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
245
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Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms
Research output: Contribution to journal › Journal article › Research › peer-review
Published