Thor Grundtvig Theander
Professor
Centre for Medical Parasitology
Blegdamsvej 3, 2200 København N, Building: 07-11-17
CMP
Blegdamsvej 3B, 2200 København N, 07 Bygning 7, Building: 07-11-TR4
Member of:
CMP-BIOENGINEERING
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T-cell response in human leishmaniasis
Kharazmi, A., Kemp, K., Ismail, A., Gasim, S., Gaafar, A., Kurtzhals, Jørgen, El Hassan, A. M., Theander, Thor Grundtvig & Kemp, M., 1999, In: Immunology Letters. 65, 1-2, p. 105-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Measurement of lumefantrine and its metabolite in plasma by high performance liquid chromatography with ultraviolet detection
Khalil, I. F., Abildrup, U., Alifrangis, L. H., Maiga, D., Alifrangis, Michael, Hoegberg, L., Vestergaard, L. S., Persson, O. P., Nyagonde, N., Lemnge, M. M., Theander, Thor Grundtvig & Bygbjerg, Ib Christian, 5 Jan 2011, In: Journal of Pharmaceutical and Biomedical Analysis. 54, 1, p. 168-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The roles of the pfcrt 76T and pfmdr1 86Y mutations, immunity and the initial level of parasitaemia, in predicting the outcome of chloroquine treatment in two areas with different transmission intensities
Khalil, I. F., Alifrangis, Michael, Tarimo, D. S., Staalsø, T., Satti, G. M. H., Theander, Thor Grundtvig, Rønn, A. M. & Bygbjerg, Ib Christian, 2005, In: Annals of Tropical Medicine and Parasitology. 99, 5, p. 441-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Limonoids from Khaya senegalensis
Khalid, S., Friedrichsen, G., Kharazmi, A., Theander, Thor Grundtvig, Olsen, C. & Christensen, Søren Brøgger, 1998, In: Phytochemistry. 49, 6, p. 1769-1772 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dichotomy of the human T cell response to Leishmania antigens. I. Th1-like response to Leishmania major promastigote antigens in individuals recovered from cutaneous leishmaniasis
Kemp, M., Hey, A. S., Kurtzhals, Jørgen, Christensen, C. B., Gaafar, A., Mustafa, M. D., Kordofani, A. A., Ismail, A., Kharazmi, A. & Theander, Thor Grundtvig, 1994, In: Clinical and Experimental Immunology. 96, 3, p. 410-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The contrasting roles of CD4+ T cells in intracellular infections in humans: leishmaniasis as an example
Kemp, M., Theander, Thor Grundtvig & Kharazmi, A., 1996, In: Trends in Immunology. 17, 1, p. 13-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dichotomy in the human CD4+ T-cell response to Leishmania parasites
Kemp, M., Kurtzhals, Jørgen, Kharazmi, A. & Theander, Thor Grundtvig, 1994, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 102, 2, p. 81-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Activation of human T lymphocytes by Leishmania lipophosphoglycan
Kemp, M., Theander, Thor Grundtvig, Handman, E., Hey, A. S., Kurtzhals, Jørgen, Hviid, Lars, Sørensen, A. L., Were, J. O., Koech, D. K. & Kharazmi, A., 1991, In: Scandinavian Journal of Immunology. 33, 2, p. 219-24 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmania donovani-reactive Th1- and Th2-like T-cell clones from individuals who have recovered from visceral leishmaniasis
Kemp, M., Kurtzhals, Jørgen, Bendtzen, K., Poulsen, L. K., Hansen, M. B., Koech, D. K., Kharazmi, A. & Theander, Thor Grundtvig, 1993, In: Infection and Immunity. 61, 3, p. 1069-73 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmaniasis
Kemp, M. & Theander, Thor Grundtvig, 2000, In: Ugeskrift for læger. 162, 46, p. 6203-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Production of interferon-¿ and interleukin-4 by human T cells recognizing Leishmania lipophosphoglycan-associated protein
Kemp, M., Kurtzhals, Jørgen, Christensen, C. B., Kharazmi, A., Jardim, A., Bendtzen, K., Gachihi, G. S., Olafson, R. W. & Theander, Thor Grundtvig, 1993, In: Immunology Letters. 38, 2, p. 137-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Th1-like human T-cell clones recognizing Leishmania gp63 inhibit Leishmania major in human macrophages
Kemp, M., Hey, A. S., Bendtzen, K., Kharazmi, A. & Theander, Thor Grundtvig, 1994, In: Scandinavian Journal of Immunology. 40, 6, p. 629-35 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human infektionsimmunologi. Basalvidenskabelige opdagelser og kliniske konsekvenser
Kemp, M., Pedersen, Bente Klarlund & Theander, Thor Grundtvig, 2000, In: Ugeskrift for læger. 162, 21, p. 3020-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interferon-¿ and interleukin-4 in human Leishmania donovani infections
Kemp, M., Kurtzhals, Jørgen, Kharazmi, A. & Theander, Thor Grundtvig, 1993, In: Immunology and Cell Biology. 71 ( Pt 6), p. 583-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Leishmania promastigote surface antigen-2 (PSA-2) is specifically recognised by Th1 cells in humans with naturally acquired immunity to L. major
Kemp, M., Handman, E., Kemp, K., Ismail, A., Mustafa, M. D., Kordofani, A. Y., Bendtzen, K., Kharazmi, A. & Theander, Thor Grundtvig, 1998, In: FEMS Immunology and Medical Microbiology. 20, 3, p. 209-18 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recognition of Leishmania antigens by T lymphocytes from nonexposed individuals
Kemp, M., Hansen, M. B. & Theander, Thor Grundtvig, 1992, In: Infection and Immunity. 60, 6, p. 2246-51 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interferon-¿- and tumour necrosis factor-a-producing cells in humans who are immune to cutaneous leishmaniasis
Kemp, K., Theander, Thor Grundtvig, Hviid, Lars, Garfar, A., Kharazmi, A. & Kemp, M., 1999, In: Scandinavian Journal of Immunology. 49, 6, p. 655-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leishmania-specific T cells expressing interferon-¿(IFN-¿) and IL-10 upon activation are expanded in individuals cured of visceral leishmaniasis
Kemp, K., Kemp, M., Kharazmi, A., Ismail, A., Kurtzhals, Jørgen, Hviid, Lars & Theander, Thor Grundtvig, 1999, In: Clinical and Experimental Immunology. 116, 3, p. 500-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Surface co-expression of two different PfEMP1 antigens on single Plasmodium falciparum-infected erythrocytes facilitates binding to ICAM1 and PECAM1
Joergensen, L., Bengtsson, D. C., Bengtsson, A., Ronander, E., Berger, S. S., Turner, Louise, Dalgaard, M. B., Cham, G. K. K., Victor, M. E., Lavstsen, Thomas, Theander, Thor Grundtvig, Arnot, D. E. & Jensen, Anja Ramstedt, 2010, In: PLoS Pathogens. 6, 9, p. e1001083Research output: Contribution to journal › Journal article › Research › peer-review
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3D7-derived Plasmodium falciparum erythrocyte membrane protein 1 is a frequent target of naturally acquired antibodies recognizing protein domains in a particular pattern independent of malaria transmission intensity
Joergensen, L., Vestergaard, L. S., Turner, Louise, Magistrado, P., Lusingu, J. P., Lemnge, M., Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2007, In: Journal of Immunology. 178, 1, p. 428-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Limited cross-reactivity among domains of the Plasmodium falciparum clone 3D7 erythrocyte membrane protein 1 family
Joergensen, L., Turner, Louise, Magistrado, P., Dahlbäck, M. A., Vestergaard, L. S., Lusingu, J. P., Lemnge, M., Salanti, Ali, Theander, Thor Grundtvig & Jensen, Anja Ramstedt, 2006, In: Infection and Immunity. 74, 12, p. 6778-84 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The kinetics of antibody binding to Plasmodium falciparum VAR2CSA PfEMP1 antigen and modelling of PfEMP1 antigen packing on the membrane knobs
Joergensen, L. M., Salanti, Ali, Dobrilovic, T., Barfod, Lea Klingenberg, Hassenkam, Tue, Theander, Thor Grundtvig, Hviid, Lars & Arnot, D. E., 2010, In: Malaria Journal. 9, 1, p. 100Research output: Contribution to journal › Journal article › Research › peer-review
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PfSETvs methylation of histone H3K36 represses virulence genes in Plasmodium falciparum
Jiang, L., Mu, J., Zhang, Q., Ni, T., Srinivasan, P., Rayavara, K., Yang, W., Turner, L., Lavstsen, T., Theander, T. G., Peng, W., Wei, G., Jing, Q., Wakabayashi, Y., Bansal, A., Luo, Y., Ribeiro, J. M. C., Scherf, A., Aravind, L., Zhu, J. & 2 others, , 11 Jul 2013, In: Nature. 499, 7457, p. 223-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum var genes expressed in children with severe malaria encode CIDRα1 domains
Jespersen, Jakob Schmidt, Wang, Christian William, Mkumbaye, S. I., Minja, D. T., Petersen, Bent, Turner, Louise, Petersen, J. E., Lusingu, J. P., Theander, Thor Grundtvig & Lavstsen, Thomas, 2016, In: EMBO Molecular Medicine. 8, 8, p. 839-850 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of gender-specific antibody recognition of products from domains of a var gene implicated in pregnancy-associated Plasmodium falciparum malaria
Jensen, Anja Ramstedt, Zornig, H. D., Buhmann, Cæcilie Christine Böck, Salanti, Ali, Koram, K. A., Riley, E. M., Theander, Thor Grundtvig, Hviid, Lars & Staalsoe, T., 2003, In: Infection and Immunity. 71, 7, p. 4193-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasmodium falciparum associated with severe childhood malaria preferentially expresses PfEMP1 encoded by group A var genes
Jensen, Anja Ramstedt, Magistrado, P., Sharp, S., Joergensen, L., Lavstsen, Thomas, Chiucchiuini, A., Salanti, Ali, Vestergaard, L. S., Lusingu, J. P., Hermsen, R., Sauerwein, R., Christensen, J., Nielsen, Morten Agertoug, Hviid, Lars, Sutherland, C., Staalsoe, T. & Theander, Thor Grundtvig, 2004, In: Journal of Experimental Medicine. 199, 9, p. 1179-90 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Humoral and cellular immune responses to glucose regulated protein 78 - a novel Leishmania donovani antigen
Jensen, Anja Ramstedt, Ismail, A., Gaafar, A., El Hassan, A. M. & Theander, Thor Grundtvig, 2002, In: Tropical Medicine & International Health. 7, 5, p. 471-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cloning, expression and antigenicity of the L. donovani reductase
Jensen, Anja Ramstedt, Kemp, K., Theander, Thor Grundtvig & Handman, E., 2001, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 109, 6, p. 461-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Serodiagnosis of Leishmania donovani infections: assessment of enzyme-linked immunosorbent assays using recombinant L. donovani gene B protein (GBP) and a peptide sequence of L. donovani GBP
Jensen, Anja Ramstedt, Gasim, S., Moller, T., Ismail, A., Gaafar, A., Kemp, M., el Hassan, A. M., Kharazmi, A., Alce, T. M., Smith, D. F. & Theander, Thor Grundtvig, 1999, In: Transactions of the Royal Society of Tropical Medicine and Hygiene. 93, 2, p. 157-60 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Serodiagnosis of cutaneous leishmaniasis: assessment of an enzyme-linked immunosorbent assay using a peptide sequence from gene B protein
Jensen, Anja Ramstedt, Gaafar, A., Ismail, A., Christensen, C. B., Kemp, M., Hassan, A. M., Kharazmi, A. & Theander, Thor Grundtvig, 1996, In: American Journal of Tropical Medicine and Hygiene. 55, 5, p. 490-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Humoral and cellular immune responses to synthetic peptides of the Leishmania donovani kinetoplastid membrane protein-11
Jensen, Anja Ramstedt, Gasim, S., Ismail, A., Gaafar, A., Kurtzhals, Jørgen, Kemp, M., El Hassan, A. M., Kharazmi, A. & Theander, Thor Grundtvig, 1998, In: Scandinavian Journal of Immunology. 48, 1, p. 103-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular and immunological characterisation of the glucose regulated protein 78 of Leishmania donovani
Jensen, Anja Ramstedt, Curtis, J., Montgomery, J., Handman, E. & Theander, Thor Grundtvig, 2001, In: BBA General Subjects. 1549, 1, p. 73-87 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A proof-of-concept study for the design of a VLP-based combinatorial HPV and placental malaria vaccine
Janitzek, C. M., Peabody, J., Thrane, Susan, H R Carlsen, P., Theander, Thor Grundtvig, Salanti, Ali, Chackerian, B., Nielsen, Morten Agertoug & Sander, Adam F. , 2019, In: Scientific Reports. 9, 1, 10 p., 5260.Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial superglue generates a full-length circumsporozoite protein virus-like particle vaccine capable of inducing high and durable antibody responses
Janitzek, C. M., Matondo, S., Thrane, Susan, Nielsen, Morten Agertoug, Kavishe, R., Mwakalinga, S. B., Theander, Thor Grundtvig, Salanti, Ali & Sander, Adam F. , 8 Nov 2016, In: Malaria Journal. 15, 9 p., 545.Research output: Contribution to journal › Journal article › Research › peer-review
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The immunogenicity of capsid-like particle vaccines in combination with different adjuvants using different routes of administration
Janitzek, C. M., Carlsen, P. H. R., Thrane, Susan, Khanna, V. M., Jakob, V., Barnier-Quer, C., Collin, N., Theander, Thor Grundtvig, Salanti, Ali, Nielsen, Morten Agertoug & Sander, Adam F. , 2021, In: Vaccines. 9, 2, 131.Research output: Contribution to journal › Journal article › Research › peer-review
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Biochemical characterization, localization and immunostimulating properties of a soluble glycoprotein, Ag1, isolated from in vitro cultures of Plasmodium falciparum
Jakobsen, P. H., Jepsen, S., Riley, E. M., Theander, Thor Grundtvig, Grellier, P., Lihme, A., Hviid, Lars, Dziegiel, Morten Hanefeld & Schrevel, J., 1990, In: Parasitology Reseach. 76, 8, p. 657-61 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased plasma levels of soluble IL-2R are associated with severe Plasmodium falciparum malaria
Jakobsen, P. H., Morris-Jones, S., Theander, Thor Grundtvig, Hviid, Lars, Hansen, M. B., Bendtzen, K., Ridley, R. G. & Greenwood, B. M., 1994, In: Clinical and Experimental Immunology. 96, 1, p. 98-103 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Soluble haemoglobin is a marker of recent Plasmodium falciparum infections
Jakobsen, P. H., Bygbjerg, Ib Christian, Theander, Thor Grundtvig, Hviid, Lars, Fujioka, H., Aikawa, M., Bayoumi, R. A. & Koch, C., 1997, In: Immunology Letters. 59, 1, p. 35-42 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibody reactivities to glutamate-rich peptides of Plasmodium falciparum parasites in humans from areas of different malaria endemicity
Jakobsen, P. H., Theander, Thor Grundtvig, Hviid, Lars, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Greenwood, B. M., Bygbjerg, Ib Christian & Heegaard, P. M., 1996, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 104, 10, p. 734-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antibody responses to Rhoptry-Associated Protein-1 (RAP-1) of Plasmodium falciparum parasites in humans from areas of different malaria endemicity
Jakobsen, P. H., Kurtzhals, Jørgen, Riley, E. M., Hviid, Lars, Theander, Thor Grundtvig, Morris-Jones, S., Jensen, J. B., Bayoumi, R. A., Ridley, R. G. & Greenwood, B. M., 1997, In: Parasite Immunology. 19, 9, p. 387-93 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Soluble Plasmodium falciparum antigens contain carbohydrate moieties important for immune reactivity
Jakobsen, P. H., Theander, Thor Grundtvig, Jensen, J. B., Mølbak, K. & Jepsen, S., 1987, In: Journal of Clinical Microbiology. 25, 11, p. 2075-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Specific T-cell recognition of the merozoite proteins rhoptry-associated protein 1 and erythrocyte-binding antigen 1 of Plasmodium falciparum
Jakobsen, P. H., Hviid, Lars, Theander, Thor Grundtvig, Afare, E. A., Ridley, R. G., Heegaard, P. M., Stuber, D., Dalsgaard, K. & Nkrumah, F. K., 1993, In: Infection and Immunity. 61, 1, p. 268-73 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Isolation and characterization of a soluble antigen complex of Plasmodium falciparum with pyrogenic properties
Jakobsen, P. H., Hviid, Lars, Theander, Thor Grundtvig, Riley, E. M., Grellier, P., Bruun, L. S., Dalsgaard, K., Schrevel, J. & Jepsen, S., 1991, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 99, 1, p. 21-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased plasma concentrations of sICAM-1, sVCAM-1 and sELAM-1 in patients with Plasmodium falciparum or P. vivax malaria and association with disease severity
Jakobsen, P. H., Morris-Jones, S., Rønn, A., Hviid, Lars, Theander, Thor Grundtvig, Elhassan, I. M., Bygbjerg, Ib Christian & Greenwood, B. M., 1994, In: Immunology. 83, 4, p. 665-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification and localization of a soluble antigen, Ag2, of 136 kDa from Plasmodium falciparum in vitro cultures
Jakobsen, P. H., Grellier, P., Theander, Thor Grundtvig, Behrendt, N., Torii, M., Aikawa, M., Schrevel, J. & Jepsen, S., 1991, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 99, 2, p. 155-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-phospholipid antibodies in patients with Plasmodium falciparum malaria
Jakobsen, P. H., Morris-Jones, S. D., Hviid, Lars, Theander, Thor Grundtvig, Høier-Madsen, M., Bayoumi, R. A. & Greenwood, B. M., 1993, In: Immunology. 79, 4, p. 653-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pathology of post-kala-azar dermal leishmaniasis: a light microscopical, immunohistochemical, and ultrastructural study of skin lesions and draining lymph nodes
Ismail, A., Gadir, A. F. A., Theander, Thor Grundtvig, Kharazmi, A. & El Hassan, A. M., 2006, In: Journal of Cutaneous Pathology. 33, 12, p. 778-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immunopathology of post kala-azar dermal leishmaniasis (PKDL): T-cell phenotypes and cytokine profile
Ismail, A., El Hassan, A. M., Kemp, K., Gasim, S., Kadaru, A. E., Moller, T., Kharazmi, A. & Theander, Thor Grundtvig, 1999, In: Journal of Pathology. 189, 4, p. 615-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The pathogenesis of post kala-azar dermal leishmaniasis from the field to the molecule: does ultraviolet light (UVB) radiation play a role?
Ismail, A., Khalil, E. A. G., Musa, A. M., El Hassan, I. M., Ibrahim, M. E., Theander, Thor Grundtvig & El Hassan, A. M., 2006, In: Medical Hypotheses. 66, 5, p. 993-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Accuracy of malaria rapid diagnostic tests in community studies and their impact on treatment of malaria in an area with declining malaria burden in north-eastern Tanzania
Ishengoma, D. S., Francis, F., Mmbando, B. P., Lusingu, J. P., Magistrado, P., Alifrangis, Michael, Theander, Thor Grundtvig, Bygbjerg, Ib Christian & Lemnge, M. M., 1 Jan 2011, In: Malaria Journal. 10, p. 176Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11256
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Real-time and label free determination of ligand binding-kinetics to primary cancer tissue specimens; a novel tool for the assessment of biomarker targeting
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Bacterial superglue enables easy development of efficient virus-like particle based vaccines
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Placental sequestration of Plasmodium falciparum malaria parasites is mediated by the interaction between VAR2CSA and chondroitin sulfate A on syndecan-1
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