Dan Stærk

Dan Stærk

Head of Department, Visiting professor

ORCID: 0000-0003-0074-298X

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  1. Published

    Comparative study of the drug delivery mechanism of L-penetratin and D-penetratin

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2018.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  2. Published

    Comprehensive analysis of commercial willow bark extracts by new technology platform: combined use of metabolomics, high-perfomance liquid chromatography-solid-phase extraction-nuclear magnetic resonance spectroscopy and high-resolution radical scavenging assay

    Agnolet, S., Wiese, S., Verpoorte, R. & Stærk, Dan, 2012, In: Journal of Chromatography A. 1262, p. 130-137 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Conformational studies of indole alkaloids corynantheine and dihydrocorynantheine by dynamic 1H NMR spectroscopy and computational methods: steric effects of ethyl vs. vinyl group

    Stærk, Dan, Norrby, P. & Jaroszewski, J. W., 2001, In: Journal of Organic Chemistry. 66, p. 2217-2221

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Coupling HPLC-SPE-NMR with a microplate-based high-resolution antioxidant assay for efficient analysis of antioxidants in food – Validation and proof-of-concept study with caper buds

    Wiese, S., Wubshet, S. G., Nielsen, J. & Stærk, Dan, 2013, In: Food Chemistry. 141, 4, p. 4010-4018

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Coupling microplate-based antibacterial assay with liquid chromatography for high-resolution growth inhibition profiling of crude extracts: Validation and proof-of-concept study with Staphylococcus aureus

    Ardalani, H., Anam, S., Kromphardt, K. J. K., Stærk, Dan & Kongstad, Kenneth Thermann, 2021, In: Molecules. 26, 6, 12 p., 1550.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Coupling of a high-resolution monoamine oxidase-A inhibitor assay and HPLC-SPE-NMR for advanced bioactivity-profiling of plant extracts

    Grosso, C., Jäger, A. & Stærk, Dan, 2013, In: Phytochemical Analysis. 24, 2, p. 141-147

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Cytotoxic activity of some phenanthroindolizidine N-Oxide alkaloids from Cynanchum vincetoxicum

    Stærk, Dan, Christensen, J., Lemmich, E., Duus, J. Ø., Olsen, C. E. & Jaroszewski, J. W., 2000, In: Journal of Natural Products. 63, 11, p. 1584-1586

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Data-dependent acquisition-mass spectrometry guided isolation of new benzoxazinoids from the roots of Acanthus mollis L.

    Bhattarai, B., Steffensen, S. K., Stærk, Dan, Laursen, B. B. & Fomsgaard, I. S., 2022, In: International Journal of Mass Spectrometry. 474, 10 p., 116815.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Detection of Seasonal Variation in Aloe Polysaccharides Using Carbohydrate Detecting Microarrays

    Isager Ahl, Louise, Al-Husseini, N., Al-Helle, S., Stærk, Dan, Grace, O. M., Willats, W. G. T., Mravec, Jozef, Jørgensen, Bodil & Rønsted, Nina, 2019, In: Frontiers in Plant Science. 10, p. 1-14 512.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Development of a bioassay-coupled HPLC-SPE-ttNMR platform for identification of α-glucosidase inhibitors in apple peel (Malus × domestica Borkh.)

    Schmidt, J. S., Lauridsen, M. B., Dragsted, Lars Ove, Nielsen, J. & Stærk, Dan, 2012, In: Food Chemistry. 135, 3, p. 1692-1699 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Discovering new natural products directly from crude extracts by HPLC-SPE-NMR: chinane diterpenes in Harpagophytum procumbens

    Clarkson, C., Stærk, Dan, Hansen, S. H., Smith, P. J. & Jaroszewski, J. W., 2006, In: Journal of Natural Products. 69, p. 527-530

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Dovyalicin-type spermidine alkaloids from Dovyalis species

    Rasmussen, B., Nkurunziza, A., Witt, M., Oketch-Rabah, H. A., Jaroszewski, J. W. & Stærk, Dan, 2006, In: Journal of Natural Products. 69, p. 1300-1304

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Dual High-Resolution α-Glucosidase and Radical Scavenging Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of Minor and Major Constituents Directly from the Crude Extract of Pueraria lobata

    Liu, B., Kongstad, Kenneth Thermann, Qinglei, S., Nyberg, N., Jäger, A. & Stærk, Dan, 13 Feb 2015, In: Journal of Natural Products. 78, 2, p. 294–300 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Dual high-resolution inhibition profiling and HPLC-HRMS-SPE-NMR analysis for identification of α-glucosidase and radical scavenging inhibitors in Solanum americanum Mill.

    Silva, E. L. E., Almeida-Lafetá, R. C., Borges, R. M. & Stærk, Dan, 2017, In: Fitoterapia. 118, p. 42-48

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Dual high-resolution α-glucosidase and PTP1B profiling combined with HPLC-PDA-HRMS-SPE-NMR analysis for the identification of potentially antidiabetic chromene meroterpenoids in Rhododendron capitatum

    Liang, Chao, Kjaerulff, Louise, Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 2021, In: Journal of Natural Products. 84, p. 2454-2467

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Edible seaweed as future functional food: Identification of α-glucosidase inhibitors by combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR

    Liu, B., Kongstad, Kenneth Thermann, Wiese, S., Jäger, A. K. & Stærk, Dan, 2016, In: Food Chemistry. 203, p. 16-22 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Effect of residual water and microwave heating on half-lifes of reagents and reactive intermediates in peptide synthesis

    Shelton, A. P. T., Pedersen, S. L., Stærk, Dan & Jensen, Knud Jørgen, 2012, In: Chemistry: A European Journal. 18, 29, p. 9024-9031 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Efficient and versatile COMU-mediated solid-phase submonomer synthesis of arylopeptoids (oligomeric N-substituted aminomethyl benzamides)

    Hjelmgaard, T., Faure, S., Stærk, Dan, Taillefumier, C. & Nielsen, J., 2011, In: Organic & Biomolecular Chemistry. 9, p. 6832-6843 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Eremane, viscidane and isozizaene diterpenoids from the leaves of Eremophila rigida and their absolute configurations

    Liang, Chao, Ndi, C., Semple, S., Buirchell, B., Coriani, S., Møller, Birger Lindberg & Stærk, Dan, 2024, In: Phytochemistry. 219, 16 p., 113972.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Erratum: "Naravelia zeylanica: Occurrence of primary benzamides in flowering plants" (Natural Product Research vol. 19 (3) (291-294))

    Jaroszewski, J. W., Stærk, Dan, Holm-Møller, S. B., Jensen, T. H., Franzyk, Henrik & Somanadhan, B., 1 Jun 2005, In: Natural Product Research. 19, 4, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  21. Published

    Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues

    Ziegler, H. L., Franzyk, Henrik, Sairafianpour, M., Tabatabai, M., Tehrani, M. D., Bagherzadeh, K., Hägerstrand, H., Stærk, Dan & Jaroszewski, J. W., 2004, In: Bioorganic & Medicinal Chemistry. 12, p. 119-127

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Evaluation of the antidiabetic potential of Psidium guajava L. (Myrtaceae) using assays for α-glucosidase, α-amylase, muscle glucose uptake, liver glucose production and triglyceride accumulation in adipocytes

    Beidokhti, M. N., Eid, H. M., Villavicencio, M. L. S., Jäger, A. K., Lobbens, E. S., Rasoanaivo, P. R., McNair, Laura M., Haddad, P. S. & Stærk, Dan, 17 Apr 2020, In: Journal of Ethnopharmacology. 257, 8 p., 112877.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Expanding the landscape of diterpene structural diversity by stereochemically controlled combinatorial biosynthesis

    Andersen-Ranberg, Johan, Kongstad, Kenneth Thermann, Nielsen, M. T., Bjerg Jensen, N., Pateraki, Irini, Bach, S. S., Hamberger, B., Zerbe, P., Stærk, Dan, Bohlmann, J., Møller, Birger Lindberg & Hamberger, B. R., 2016, In: Angewandte Chemie International Edition. 55, 6, p. 2142-2146 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks

    Ignea, C., Raadam, Morten Hessellund, Koutsaviti, A., Zhao, Yong, Duan, Yaotao, Harizani, M., Miettinen, Karel, Georgantea, P., Rosenfeldt, M., Viejo-Ledesma, S. E., Petersen, Mikael Agerlin, Bredie, Wender, Stærk, Dan, Roussis, V., Ioannou, E. & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 5188.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Expedient solution-phase synthesis and NMR studies of arylopeptoids

    Hjelmgaard, T., Faure, S., Stærk, Dan, Taillefumier, C. & Nielsen, J., 2011, In: European Journal of Organic Chemistry. 2011, 22, p. 4121-4132 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Facilitated visual interpretation of scores in principal component analysis by bioactivity-labeling of 1H NMR spectra - metabolomics investigation and identification of a new α-glucosidase inhibitor in Radix Astragali

    Liu, Y., Nyberg, N., Jäger, A. K. & Stærk, Dan, 2017, In: Molecules. 22, 3, 12 p., 411.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Fluorophore labeling of a cell-penetrating peptide induces differential effects on its cellular distribution and affects cell viability

    Birch, D., Christensen, M. V., Stærk, Dan, Franzyk, Henrik & Nielsen, Hanne Mørck, 2017, In: B B A - Biomembranes. 1859, 12, p. 2483-2494

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Food preference and performance of the larvae of a specialist herbivore: variation among and within host-plant populations

    Leimu, R., Riipi, M. & Stærk, Dan, 2005, In: Acta Oecologica. 28, p. 325-330

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Forbedret test af nye lægemidler mod malaria

    Christensen, J., Stærk, Dan, Ziegler, H. L., Sairafianpour, M. & Jaroszewski, J. W., 2001, In: Lægemiddelforskning. p. 8-9

    Research output: Contribution to journal › Journal article › Communication

  30. Published

    Fremtidens bæredygtige medicin fra naturen: Nye teknologier hjælper med at finde nålen i høstakken

    Stærk, Dan, 2022, In: Pharma. 2022, 2, p. 20-22

    Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication

  31. Published

    Fremtidens funktionelle fødevarer - et vigtigt middel i kampen mod livsstilssygdomme

    Stærk, Dan, 2012, Profil/Fødevarer & Sundhed. København: Københavns Universitet, Kommunikation, p. 18-19 2 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  32. Published

    Fungal plasma membrane H+-ATPase inhibitory activity of o-hydroxybenzylated flavanones and chalcones from Uvaria chamae P. Beauv

    Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., winther, A. L. & Stærk, Dan, 20 Jun 2015, In: Fitoterapia. 105, p. 102-106 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Furolabdane diterpenoids from Pseudodictamnus aucheri (Boiss.) Salmaki & Siadati (Lamiaceae) as chemophenetic markers

    Sadani, S., Sarrafi, Y. & Stærk, Dan, 2021, In: Biochemical Systematics and Ecology. 98, 4 p., 104304.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    HPLC-HRMS-SPE-NMR combined with high resolution in vitro screening for natural fungicides

    Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., Winther, A. & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  35. Published

    HPLC-HRMS-SPE-NMR for accelerated identification of compounds in complex plant extracts: New coumarine derivatives from Coleonema album (Thunb.) Bartl. & Wendl

    de Cássia Lemos Lima, R., Gramsbergen, S. M., Van Staden, J., Jäger, A. K., Kongstad, Kenneth Thermann & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  36. Published

    HPLC-NMR Techniques for Plant Extract Analysis

    Stærk, Dan, Lambert, M. & Jaroszewski, J. W., 20 Mar 2008, Medicinal Plant Biotechnology: From Basic Research to Industrial Applications. Wiley-VCH, p. 29-48 20 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  37. Published

    HPLC-NMR techniques for plant extract analysis

    Stærk, Dan, Lambert, M. & Jaroszewski, J. W., 2006, Medicinal Plant Biotechnology. From Basic Research to Applications. Kayser, O. & Quax, W. J. (eds.). Weinheim: Wiley-VCH, p. 29-48

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  38. Published

    HPLC-SPE-NMR for combinatorial biosynthetic investigations – expanding the landscape of diterpene structural diversity

    Kongstad, Kenneth Thermann, Andersen-Ranberg, Johan, Hamberger, B. R. & Stærk, Dan, 2016. 1 p.

    Research output: Contribution to conference › Poster › Research

  39. Published

    HPLC-SPE-NMR hyphenation in natural products research: optimization of analysis of Croton membranaceus extract

    Lambert, M., Stærk, Dan, Hansen, S. H. & Jaroszewski, J. W., 2005, In: Magnetic Resonance in Chemistry. 43, p. 771-775

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    HPLC-SPE-NMR identification of a novel metabolite containing the benzo[c]oxepin skeleton from the endophytic fungus Pestalotiopsis virgatula culture

    Kesting, J. R., Stærk, Dan, Tejesvi, M. V., Kini, K. R., Prakash, H. S. & Jaroszewski, J. W., 2009, In: Planta Medica. 75, 10, p. 1104-1106 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Hemolymph metabolites and osmolality are tightly linked to cold tolerance of Drosophila species: a comparative study

    Olsson, T., MacMillan, H. A., Nyberg, N., Stærk, Dan, Malmendal, A. & Overgaard, J., 15 Aug 2016, In: The Journal of Experimental Biology. 219, 16, p. 2504-2513 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans

    Frandsen, R. J. N., Khorsand-Jamal, P., Kongstad, Kenneth Thermann, Nafisi, M., Kannangara, R. M., Stærk, Dan, Okkels, F. T., Binderup, K., Madsen, B., Møller, Birger Lindberg, Thrane, U. & Mortensen, U. H., 2018, In: Scientific Reports. 8, p. 1-10 10 p., 12853.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    High resolution antioxidant assay guided HPLC-HRMS-SPE-NMR analysis of Penicillium namyslowskii extract

    Wubshet, S. G., Nyberg, N. & Stærk, Dan, 2012.

    Research output: Contribution to conference › Poster › Research

  44. Published

    High resolution techniques: General discussion

    Adair, E., Afonso, C., Bell, N. G. A., Davies, A. N., Delsuc, M. A., Godfrey, R., Goodacre, R., Hawkes, J. A., Hertkorn, N., Jones, D., Lameiras, P., Le Guennec, A., Lubben, A., Nilsson, M., Paša-Tolić, L., Richards, J., Rodgers, R. P., Rüger, C. P., Schmitt-Kopplin, P., Schoenmakers, P. J. & 8 others, Sidebottom, P., Stærk, Dan, Summerfield, S., Uhrín, D., Van Delft, P., Van Der Hooft, J. J. J., Van Zelst, F. H. M. & Zherebker, A., 1 Jan 2019, In: Faraday Discussions. 218, p. 247-267 21 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  45. Published

    High-dose naloxone, an experimental tool uncovering latent sensitisation: pharmacokinetics in humans.

    Papathanasiou, T., Springborg, A., Kongstad, Kenneth Thermann, Stærk, Dan, Møller, Kirsten, Taylor, B. K., Lund, Trine Meldgaard & Werner, M. U., 2019, In: British Journal of Anaesthesia. 123, 2, p. e204-e214

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    High-resolution Assays Combined with HPLC-HRMS-SPE-ttNMR for Identification of Antidiabetic Compounds in root of Scutellaria Baicalensis

    Tahtah, Y., Jønsson, L. H., Nyberg, N., Jäger, A. & Stærk, Dan, 2014.

    Research output: Contribution to conference › Poster › Research

  47. Published

    High-resolution PTP1B inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of PTP1B inhibitors from Miconia albicans

    Lima, R. D. C. L., Kongstad, Kenneth Thermann, Kato, L., José das Silva, M., Franzyk, Henrik & Stærk, Dan, 2018, In: Molecules. 23, 7, 13 p., 1755.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    High-resolution PTP1B inhibition profiling combined with high-performance liquid chromatography - high-resolution mass spectrometry - solid-phase extraction - nuclear magnetic resonance spectroscopy: Proof-of-concept and antidiabetic constituents in crude extract of Eremophila lucida

    Tahtah, Y., Wubshet, S. G., Kongstad, Kenneth Thermann, Heskes, A. M., Pateraki, Irini, Møller, Birger Lindberg, Jäger, A. & Stærk, Dan, 2016, In: Fitoterapia. 110, p. 52-58 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    High-resolution assays combined with HPLC for identification of antidiabetic constituents in Vietnamese plants

    Trinh, T. D. B., Stærk, Dan & Jäger, A. K., 26 Aug 2015.

    Research output: Contribution to conference › Poster › Research

  50. Published

    High-resolution bacterial growth inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antibacterial constituents in Chinese plants used to treat snakebites

    Liu, Y., Nielsen, M., Stærk, Dan & Jäger, A., 2014, In: Journal of Ethnopharmacology. 155, 2, p. 1276-1283 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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