Filip Krag Knop
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Member of:
Internal Medicine: Endocrinology
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'No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia': authors' response
Ebdrup, Bjørn, Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag & Glenthøj, Birte Yding, Nov 2017, In: Acta Psychiatrica Scandinavica. 136, 5, p. 526-527Research output: Contribution to journal › Comment/debate › Research
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100 years of glucagon and 100 more
Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Cherrington, A. D., Finan, B., Gluud, Lise Lotte, Dean, E. D., Campbell, J. E., Bloom, S. R., Tan, T. M., Knop, Filip Krag & Müller, T. D., 2023, In: Diabetologia. 66, p. 1378–1394Research output: Contribution to journal › Review › Research › peer-review
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2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans
Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17Research output: Contribution to journal › Journal article › Research › peer-review
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MYC mRNA expression throughout the intestine is not associated with body mass index or type 2 diabetes
Ellegaard, A. & Knop, Filip Krag, 2022, In: Endocrinology, Diabetes and Metabolism. 5, 2, 4 p., 00327.Research output: Contribution to journal › Comment/debate › Research
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N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis
Grevengoed, Trisha Jean, Trammell, Sam, McKinney, M. K., Petersen, N., Cardone, R. L., Svenningsen, J. S., Ogasawara, D., Nexøe-Larsen, C. C., Knop, Filip Krag, Schwartz, Thue W., Kibbey, R. G., Cravatt, B. F. & Gillum, M. P., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 49, p. 24770-24778Research output: Contribution to journal › Journal article › Research › peer-review
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A 25-year-old woman with type 2 diabetes and liver disease
Junker, A. E., Gluud, Lise Lotte, Pedersen, J., Langhoff, J. L., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2014, In: Case Reports in Gastroenterology. 8, 3, p. 398-403 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Pharmacological and Clinical Overview of Oral Semaglutide for the Treatment of Type 2 Diabetes
Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Drugs. 81, p. 1003-1030 28 p.Research output: Contribution to journal › Review › Research › peer-review
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A comprehensive compartmental model of blood glucose regulation for healthy and type 2 diabetic subjects
Vahidi, O., Kwok, K. E., Gopaluni, R. B. & Knop, Filip Krag, 2016, In: Medical & Biological Engineering & Computing. 54, 9, p. 1383-1398 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment
Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.Research output: Contribution to journal › Journal article › Research › peer-review
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A gut feeling about glucagon: Eje Prize 2018
Knop, Filip Krag, 2018, In: European Journal of Endocrinology. 178, 6, p. R267-R280 14 p.Research output: Contribution to journal › Review › Research › peer-review
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A liver secretome gene signature-based approach for determining circulating biomarkers of NAFLD severity
Hagemann, C. A., Legart, C., Møllerhøj, M. B., Madsen, M. R., Hansen, H. H., Kønig, M. J., Helgstrand, Frederik, Hjørne, F. P., Toxværd, A., Langhoff, J. L., Kielgast, U. L., Gluud, Lise Lotte, Ægidius, H., Rigbolt, K. T. G., Vilsbøll, Tina, Jelsing, J. & Knop, Filip Krag, 2022, In: PLoS ONE. 17, 10, 19 p., e0275901.Research output: Contribution to journal › Journal article › Research › peer-review
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A role for exogenous GLP-1 in the management of postprandial hypoglycaemia after Roux-en-Y gastric bypass?
Øhrstrøm, C. C. & Knop, Filip Krag, 2019, In: European Journal of Endocrinology. 181, 3, p. C5-C8Research output: Contribution to journal › Comment/debate › Research
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A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite
Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291Research output: Contribution to journal › Journal article › Research › peer-review
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Acarbose diminishes postprandial suppression of bone resorption in patients with type 2 diabetes
Dalsgaard, N. B., Gasbjerg, Lærke Smidt, Helsted, M. M., Hansen, L. S., Hansen, N. L., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Bone. 170, 116687.Research output: Contribution to journal › Journal article › Research › peer-review
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Accuracy of continuous glucose monitoring during exercise-related hypoglycemia in individuals with type 1 diabetes
Maytham, K., Hagelqvist, P. G., Engberg, S., Forman, Julie Lyng, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag, Vilsbøll, Tina & Andersen, A., 2024, In: Frontiers in Endocrinology. 15, 9 p., 1352829.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls
Andersen, A., Jørgensen, P. G., Bagger, J., Baldassarre, M. P. A., Christensen, Mikkel Bring, Pedersen-Bjergaard, Ulrik, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 6, p. 1123-1131Research output: Contribution to journal › Journal article › Research › peer-review
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Acute concomitant GIP receptor antagonism during GLP-1 receptor agonism does not affect appetite, resting energy expenditure or food intake in patients with type 2 diabetes and overweight/obesity
Stensen, S., Krogh, L. L., wbf943, wbf943, Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 9, p. 1882-1887Research output: Contribution to journal › Journal article › Research › peer-review
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Acute hypoglycemia and risk of cardiac arrhythmias in insulin-treated type 2 diabetes and controls
Andersen, A., Bagger, J. I., Baldassarre, M. P., Christensen, Mikkel Bring, Abelin, K. U., Faber, Jens, Pedersen-Bjerregaard, U., Holst, Jens Juul, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: European Journal of Endocrinology. 185, 2, p. 343-353 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Adaptive changes in pancreas post Roux-en-Y gastric bypass induced weight loss
Lautenbach, A., Wernecke, M., Riedel, N., Veigel, J., Yamamura, J., Keller, S., Jung, R., Busch, P., Mann, O., Knop, Filip Krag, Holst, Jens Juul, Meier, J. J. & Aberle, J., Oct 2018, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 34, 7, p. 1-8 e3025.Research output: Contribution to journal › Journal article › Research › peer-review
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Adult atopic dermatitis and the risk of type 2 diabetes
Andersen, Y. M. F., Egeberg, A., Gislason, Gunnar Hilmar, Skov, Lone, Knop, Filip Krag & Thyssen, Jacob Pontoppidan, Mar 2017, In: The Journal of allergy and clinical immunology. 139, 3, p. 1057-1059 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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Adverse drug reactions associated with the use of liraglutide in patients with type 2 diabetes-focus on pancreatitis and pancreas cancer
Chalmer, T., Almdal, Thomas Peter, Vilsbøll, Tina & Knop, Filip Krag, 2015, In: Expert Opinion on Drug Safety. 14, 1, p. 171-180Research output: Contribution to journal › Review › Research › peer-review
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Albiglutide for treating type 2 diabetes: an evaluation of pharmacokinetics/pharmacodynamics and clinical efficacy
Brønden, A., Naver, S. V., Knop, Filip Krag & Christensen, M., 2015, In: Expert Opinion on Drug Metabolism & Toxicology. 11, 9, p. 1493-1503 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alpha- and beta-cell abnormalities in haemoglobin A1c-defined prediabetes and type 2 diabetes
Calanna, S., Scicali, R., Di Pino, A., Knop, Filip Krag, Piro, S., Rabuazzo, A. M. & Purrello, F., 2014, In: Acta Diabetologica. 51, 4, p. 567-575Research output: Contribution to journal › Journal article › Research › peer-review
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Alterations in blood microbiota after colonic cancer surgery
Søby, J. H., Watt, S. K., Vogelsang, R. P., Servant, F., Lelouvier, B., Raskov, H., Knop, Filip Krag & Gögenur, Ismail, 2020, In: BJS open. 4, 6, p. 1227-1237Research output: Contribution to journal › Journal article › Research › peer-review
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Amylin and Calcitonin: Potential Therapeutic Strategies to Reduce Body Weight and Liver Fat
Mathiesen, D. S., Lund, A., Vilsbøll, Tina, Knop, Filip Krag & Bagger, J. I., 2021, In: Frontiers in Endocrinology. 11, 617400.Research output: Contribution to journal › Review › Research › peer-review
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An Extended Minimal Model of OGTT: estimation of α- and β-cell dysfunction, insulin resistance, and the incretin effect
Subramanian, V., Bagger, J. I., Harihar, V., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 326, 2, p. E182-E205Research output: Contribution to journal › Journal article › Research › peer-review
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An overview of obesity mechanisms in humans: Endocrine regulation of food intake, eating behaviour and common determinants of body weight
Theilade, Karen Simone, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetes, Obesity and Metabolism. 23, S1, p. 17-35 19 p.Research output: Contribution to journal › Review › Research › peer-review
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Antidiabetes Agents and Incident Depression: A Nationwide Population-Based Study
Kessing, Lars Vedel, Rytgaard, Helene Charlotte Wiese, Ekstrøm, Claus Thorn, Knop, Filip Krag, Berk, M. & Gerds, Thomas Alexander, 2020, In: Diabetes Care. 43, 12, p. 3050-3060Research output: Contribution to journal › Journal article › Research › peer-review
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Arginine-vasopressin mediates counter-regulatory glucagon release and is diminished in type 1 diabetes
Kim, A., Knudsen, J. G., Madara, J. C., Benrick, A., Hill, T. G., Kadir, L. A., Kellard, J. A., Mellander, L., Miranda, C., Lin, H., James, T., Suba, K., Spigelman, A. F., Wu, Y., Macdonald, P. E., Asterholm, I. W., Magnussen, T., Christensen, M., Vilsbøll, T., Salem, V. & 4 others, , 2021, In: eLife. 10, 29 p., e72919.Research output: Contribution to journal › Journal article › Research › peer-review
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Association between topical corticosteroid use and type 2 diabetes in two European population-based adult cohorts
Andersen, Y. M. F., Egeberg, A., Ban, L., Gran, S., Williams, H. C., Francis, N. A., Knop, Filip Krag, Gislason, Gunnar Hilmar, Skov, Lone & Thyssen, Jacob Pontoppidan, 2019, In: Diabetes Care. 42, 6, p. 1095-1103Research output: Contribution to journal › Journal article › Research › peer-review
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Associations of hypoglycaemia and glycaemic variability with cardiac arrhythmias using a long-term monitoring approach in insulin-treated patients with type 2 diabetes
Andersen, A., Bagger, J. I., Sorensen, S. K., Baldassarre, M. P. A., Pedersen-Bjergaard, Ulrik, Forman, Julie Lyng, Gislason, Gunnar Hilmar, Lindhardt, T. B., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-135 257.Research output: Contribution to journal › Conference abstract in journal › Research
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Associations of hypoglycemia, glycemic variability and risk of cardiac arrhythmias in insulin-treated patients with type 2 diabetes: a prospective, observational study
Andersen, A., Bagger, J. I., Sørensen, S. K., Baldassarre, M. P. A., Pedersen-Bjergaard, Ulrik, Forman, Julie Lyng, Gislason, Gunnar Hilmar, Lindhardt, T. B., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Cardiovascular Diabetology. 20, 1, 10 p., 241.Research output: Contribution to journal › Journal article › Research › peer-review
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Author Response to Letter to the Editor regarding “the Epidemiology of Bile Acid Diarrhea in Denmark” [Response to Letter]
Ellegaard, A. M., Kårhus, M. L., Knop, Filip Krag & Kårhus, L. L., 2024, In: Clinical Epidemiology. 16, p. 5-6 2 p.Research output: Contribution to journal › Letter › Research › peer-review
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Azithromycin and hydroxychloroquine in hospitalised patients with confirmed COVID-19: a randomised double-blinded placebo-controlled trial
Sivapalan, P. & ProPAC-COVID writing group on behalf of the ProPAC-COVID Study Group, P. W. G. O. B. O. T. P. S. G., 2022, In: European Respiratory Journal. 59, 1, 2100752.Research output: Contribution to journal › Journal article › Research › peer-review
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Bariatric surgery in patients with non-alcoholic fatty liver disease from pathophysiology to clinical effects
Laursen, T. L., Hagemann, C. A., Wei, C., Kazankov, K., Thomsen, K. L., Knop, Filip Krag & Gronbaek, H., 2019, In: World Journal of Hepatology. 11, 2, p. 138-149Research output: Contribution to journal › Review › Research › peer-review
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Behandling med duodenal-jejunal bypass-sleeve ved svær overvægt
Rohde, U., Gylvin, S., Vilmann, Peter, Friis, S. U., Langholz, Ebbe, Vilsbøll, T. & Knop, Filip Krag, 29 Sep 2014, In: Ugeskrift for Laeger. 176, 37, p. 1874-1877 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Benefits and Harms of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Storgaard, H., Gluud, Lise Lotte, Bennett, C., Grøndahl, M. F., Christensen, Mikkel Bring, Knop, Filip Krag & Vilsbøll, Tina, 2016, In: PLOS ONE. 11, 11, 23 p., e0166125.Research output: Contribution to journal › Review › Research › peer-review
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Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2
Holm, Stephanie Kjærulff, Husted, Anna Sofie, Skov, Louise Julie, Morville, T. H., Hagemann, C. A., Jorsal, T., Dall, M., Jakobsen, A., Klein, A. B., Treebak, Jonas Thue, Knop, Filip Krag, Schwartz, Thue W., Clemmensen, Christoffer & Holst, Birgitte, 2022, In: Endocrinology. 163, 6, 13 p., bqac038.Research output: Contribution to journal › Journal article › Research › peer-review
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Betydningen af inkretinhormonerne glucose-dependent insulinotropic peptide og glucagon-like peptide-1 for patogenesen ved type 2-diabetes mellitus
Vilsbøll, Tina & Knop, Filip Krag, 28 May 2007, In: Ugeskrift for Laeger. 169, 22, p. 2101-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bifidobacterium breve Bif195 ameliorates aspirin-induced gastric mucosal damage: A randomised, double blind, placebo-controlled crossover trial
Løn, N., Engel, S., Damholt, A., Mortensen, B., Haaber, A. B., Wellejus, A. & Knop, Filip Krag, 2024, In: Alimentary Pharmacology and Therapeutics. 59, 3, p. 341-349 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bile acid sequestrants: Glucose-lowering mechanisms and efficacy in type 2 diabetes
Hansen, M., Sonne, David Peick & Knop, Filip Krag, May 2014, In: Current Diabetes Reports. 14, 5, 482.Research output: Contribution to journal › Review › Research › peer-review
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Bile acid sequestrants for glycemic control in patients with type 2 diabetes: A systematic review with meta-analysis of randomized controlled trials
Hansen, M., Sonne, David Peick, Mikkelsen, K. H., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, May 2017, In: Journal of Diabetes and its Complications. 31, 5, p. 918-927 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bile acid-farnesoid X receptor-fibroblast growth factor 19 axis in patients with short bowel syndrome: The randomized, glepaglutide phase 2 trial
Hvistendahl, M. K., Naimi, R. M., Hansen, S. H., Rehfeld, Jens Frederik, Kissow, Hannelouise, Pedersen, Jens, Dragsted, Lars Ove, Sonne, D. P., Knop, Filip Krag & Jeppesen, Palle Bekker, 2022, In: Journal of Parenteral and Enteral Nutrition. 46, 4, p. 923-935 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bile-induced secretion of glucagon-like peptide-1: pathophysiological implications in type 2 diabetes?
Knop, Filip Krag, 1 Jul 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 1, p. E10-3Research output: Contribution to journal › Journal article › Research › peer-review
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Biomarkører for kardiovaskulær sygdom ved type 2-diabetes
Krogh, S. K., Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2019, In: Ugeskrift for Laeger. 181, 6 p., V10180711.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone Status in Obese, Non-diabetic, Antipsychotic-Treated Patients, and Effects of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide on Bone Turnover Markers and Bone Mineral Density
Eriksson, R., Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jorgensen, N. R., Knop, Filip Krag & Ebdrup, Bjørn, 2019, In: Frontiers in Psychiatry. 9, 7 p., 781.Research output: Contribution to journal › Journal article › Research › peer-review
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Bone Turnover Markers in Patients With Nonalcoholic Fatty Liver Disease and/or Type 2 Diabetes During Oral Glucose and Isoglycemic Intravenous Glucose
Maagensen, H., Junker, A. E., Jorgensen, N. R., Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 2042-2049 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Call for prospective studies of continuous glucose monitoring to define the glycaemic response to bariatric surgery
Bally, L., Khoo, B., Knop, Filip Krag, Madsbad, Sten, Patti, M. & Tan, T., 2023, In: The Lancet Diabetes and Endocrinology. 11, 10, p. 712-714 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Cardiovascular biomarkers in clinical studies of type 2 diabetes
Baldassarre, M. P. A., Andersen, A., Consoli, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1350-1360Research output: Contribution to journal › Review › Research › peer-review
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Cardiovascular effects of high-dose glucagon: a randomised clinical trial
Petersen, K. M., Bogevig, S., Riis, T., Andersson, N. A. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S231Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 40100368
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L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
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Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Research output: Contribution to journal › Journal article › Research › peer-review
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