Yoshiki Narimatsu
Associate Professor
Glycomics Program
Blegdamsvej 3
2200 København N.
- Published
A Genetic Approach to Display and Dissect the Cancer-Associated O-Glycoepitome
Clausen, Henrik, Nason, R., Mandel, Ulla & Narimatsu, Yoshiki, 2020, In: FASEB Journal. 34, S1, 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
A family of di-glutamate mucin-degrading enzymes that bridges glycan hydrolases and peptidases
Narimatsu, Yoshiki, Büll, C., Taleb, V., Liao, Q., Compañón, I., Sánchez-Navarro, D., Durbesson, F., Vincentelli, R., Hansen, Lars, Corzana, F., Rovira, C., Henrissat, B., Clausen, Henrik, Joshi, Hiren Jitendra & Hurtado-Guerrero, R., 2024, In: Nature Catalysis. 7, p. 386–400 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A strategy for generating cancer-specific monoclonal antibodies to aberrant O-glycoproteins: identification of a novel dysadherin-Tn antibody
Steentoft, C., Fuhrmann, M., Battisti, F., Van Coillie, Julie, Madsen, Thomas Daugbjerg, Campos, D., Halim, Adnan, Vakhrushev, Sergey, Joshi, Hiren Jitendra, Schreiber, H., Mandel, Ulla & Narimatsu, Yoshiki, 2019, In: Glycobiology. 29, 4, p. 307-319 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A validated collection of mouse monoclonal antibodies to human glycosyltransferases functioning in mucin-type O-glycosylation.
Steentoft, C., Yang, Zhang, Wang, S., Ju, T., Vester-Christensen, M. B., Festari, M. F., King-Smith, S. L., Moremen, K., Larsen, I. S. B., Goth, C. K., Schjoldager, Katrine Ter-Borch Gram, Hansen, Lars, Bennett, Eric Paul, Mandel, Ulla & Narimatsu, Yoshiki, 2019, In: Glycobiology. 29, 9, p. 645–656 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome
Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Zhang, Y., Gomes, C., Chen, Yen-Hsi, Lorenzetti, F., Furukawa, S., Schjoldager, Katrine Ter-Borch Gram, Hansen, Lars, Clausen, Henrik, Bennett, Eric Paul & Wandall, Hans H., 2018, In: Glycobiology. 28, 5, p. 295–305Research output: Contribution to journal › Journal article › Research › peer-review
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Advances in mass spectrometry driven O-glycoproteomics
Levery, S. B., Steentoft, C., Halim, Adnan, Narimatsu, Yoshiki, Clausen, Henrik & Vakhrushev, Sergey, Jan 2015, In: B B A - Reviews on Cancer. 1850, 1, p. 33-42 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells
Narimatsu, Y., Joshi, H. J., Nason, R., Van Coillie, J., Karlsson, R., Sun, L., Ye, Z., Chen, Y-H., Schjoldager, K. T., Steentoft, C., Furukawa, S., Bensing, B. A., Sullam, P. M., Thompson, A. J., Paulson, J. C., Büll, C., Adema, G. J., Mandel, U., Hansen, L., Bennett, E. P. & 4 others, , 2019, In: Molecular Cell. 75, 2, p. 394-407, e1-e5Research output: Contribution to journal › Journal article › Research › peer-review
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Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
Coelho, H., Rivas, M. D. L., Grosso, A. S., Diniz, A., Soares, C. O., Francisco, R. A., Dias, J. S., Compañon, I., Sun, L., Narimatsu, Yoshiki, Vakhrushev, Sergey, Clausen, Henrik, Cabrita, E. J., Jiménez-Barbero, J., Corzana, F., Hurtado-Guerrero, R. & Marcelo, F., 2022, In: JACS Au. 2, 3, p. 631-645 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell-Based Glycan Arrays — A Practical Guide to Dissect the Human Glycome
Büll, C., Joshi, Hiren Jitendra, Clausen, Henrik & Narimatsu, Yoshiki, 2020, In: STAR Protocols. 1, 1, 100017.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of Binding Epitopes of CA125 Monoclonal Antibodies
da Silva, L. P. M., Narimatsu, Yoshiki, Halim, Adnan, Vieira Campos, D. A., Yang, Zhang, Tarp, M. P. A., Pereira, P. J. B., Mandel, Ulla, Bennett, Eric Paul, Vakhrushev, Sergey, Levery, S. B., David, L. & Clausen, Henrik, 3 Jul 2014, In: Journal of Proteome Research. 13, 7, p. 3349-59 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of galactosyltransferase and sialyltransferase genes mediating the elongation of the extracellular O-GlcNAc glycans
Tsukamoto, Y., Tsukamoto, N., Saiki, W., Tashima, Y., Furukawa, J. I., Kizuka, Y., Narimatsu, Yoshiki, Clausen, Henrik, Takeuchi, H. & Okajima, T., 2024, In: Biochemical and Biophysical Research Communications. 703, 6 p., 149610.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct observation of glycans bonded to proteins and lipids at the single-molecule level
Anggara, K., Sršan, L., J, Tommy, Wu, X., Rauschenbach, S., Narimatsu, Yoshiki, Clausen, Henrik, Ziegler, T., Miller, Rebecca Louise & Kern, K., 2023, In: Science (New York, N.Y.). 382, 6667, p. 219-223 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of an O-mannosylation pathway selectively serving cadherins and protocadherins
Larsen, I. S. B., Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Siukstaite, L., Harrison, O. J., Brasch, J., Goodman, K. M., Hansen, Lars, Shapiro, L., Honig, B., Vakhrushev, Sergey, Clausen, Henrik & Halim, Adnan, 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 42, p. 11163-11168 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Display of the human mucinome with defined O-glycans by gene engineered cells
Nason, R., Büll, C., Konstantinidi, A., Sun, L., Ye, Z., Halim, A., Du, W., Sørensen, D. M., Durbesson, F., Furukawa, S., Mandel, U., Joshi, H. J., Dworkin, L. A., Hansen, L., David, L., Iverson, T. M., Bensing, B. A., Sullam, P. M., Varki, A., Vries, E. D. & 6 others, , 2021, In: Nature Communications. 12, 1, 16 p., 4070.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamics of Indel Profiles Induced by Various CRISPR/Cas9 Delivery Methods
Kosicki, M., Rajan, S. S., Lorenzetti, F. C., Wandall, Hans H., Narimatsu, Yoshiki, Metzakopian, E. & Bennett, Eric Paul, 2017, In: Progress in Molecular Biology and Translational Science. 152, p. 49-67 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enterovirus D-68 Infection of Primary Rat Cortical Neurons: Entry, Replication, and Functional Consequences
Poelaert, K. C. K., van Kleef, R. G. D. M., Liu, M., van Vliet, A., Lyoo, H., Gerber, L. S., Narimatsu, Yoshiki, Büll, C., Clausen, Henrik, de Vries, E., Westerink, R. H. S. & van Kuppeveld, F. J. M., 2023, In: mBio. 14, 2, e0024523.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exploring Regulation of Protein O-Glycosylation in Isogenic Human HEK293 Cells by Differential O-Glycoproteomics
Narimatsu, Yoshiki, Joshi, Hiren Jitendra, Schjoldager, Katrine Ter-Borch Gram, Hintze, John, Halim, Adnan, Steentoft, C., Nason, R., Mandel, Ulla, Bennett, Eric Paul, Clausen, Henrik & Vakhrushev, Sergey, 2019, In: Molecular and Cellular Proteomics. 18, 7, p. 1396-1409Research output: Contribution to journal › Journal article › Research › peer-review
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Exploring the glycosylation of mucins by use of O-glycodomain reporters recombinantly expressed in glycoengineered HEK293 cells
Konstantinidi, Andriana, Nason, R., Čaval, T., Sun, L., Sørensen, Daniel Madriz, Furukawa, S., Ye, Z., Vincentelli, R., Narimatsu, Yoshiki, Vakhrushev, Sergey & Clausen, Henrik, 2022, In: Journal of Biological Chemistry. 298, 4, 101784.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fine-tuning limited proteolysis - A novel role for regulated site-specific O-glycosylation in beta 1-Adrenergic Receptor cleavage and function
Goth, C. K., Tuhkanen, H. E., Khan, H., Wang, S., Narimatsu, Yoshiki, Hansen, L. H., Overall, C., Clausen, Henrik, Schjoldager, Katrine Ter-Borch Gram & Petaja-Repo, U., Dec 2017, In: Glycobiology. 27, 12, p. 1204-1204 84.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Genetic glycoengineering in mammalian cells
Narimatsu, Yoshiki, Büll, C., Chen, Yen-Hsi, Wandall, Hans H., Yang, Zhang & Clausen, Henrik, 2021, In: Journal of Biological Chemistry. 296, 25 p., 100448.Research output: Contribution to journal › Review › Research › peer-review
- Published
Genome editing using FACS enrichment of nuclease-expressing cells and indel detection by amplicon analysis
Lonowski, Lindsey Allison, Narimatsu, Yoshiki, Riaz, A., Delay, C. M. E., Yang, Zhang, Niola, Francesco, Duda, K., Ober, Elke, Clausen, Henrik, Wandall, Hans H., Hansen, S. H., Bennett, Eric Paul & Frödin, Morten, Mar 2017, In: Nature Protocols. 12, 3, p. 581-603 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Global view of human protein glycosylation pathways and functions
Schjoldager, Katrine Ter-Borch Gram, Narimatsu, Yoshiki, Joshi, Hiren Jitendra & Clausen, Henrik, 2020, In: Nature Reviews Molecular Cell Biology. 21, p. 729–749Research output: Contribution to journal › Review › Research › peer-review
- Published
Glycoengineering of NK Cells with Glycan Ligands of CD22 and Selectins for B-Cell Lymphoma Therapy
Hong, S., Yu, C., Wang, P., Shi, Y., Cao, W., Cheng, B., Chapla, D. G., Ma, Y., Li, J., Rodrigues, E., Narimatsu, Yoshiki, Yates, J. R., Chen, X., Clausen, Henrik, Moremen, K. W., Macauley, M. S., Paulson, J. C. & Wu, P., 2021, In: Angewandte Chemie - International Edition. 60, 7, p. 3603-3610Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycosyltransferase genes that cause monogenic congenital disorders of glycosylation are distinct from glycosyltransferase genes associated with complex diseases
Joshi, Hiren Jitendra, Hansen, Lars, Narimatsu, Yoshiki, Freeze, H. H., Henrissat, B., Bennett, Eric Paul, Wandall, Hans H., Clausen, Henrik & Schjoldager, Katrine Ter-Borch Gram, 2018, In: Glycobiology. 28, 5, p. 284-294Research output: Contribution to journal › Journal article › Research › peer-review
- Published
H3N2 influenza A virus gradually adapts to human-type receptor binding and entry specificity after the start of the 1968 pandemic
Liu, M., Bakker, A. S., Narimatsu, Yoshiki, van Kuppeveld, F. J. M., Clausen, Henrik, de Haan, C. A. M. & de Vries, E., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 31, e2304992120.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38035013
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Multiple distinct O-Mannosylation pathways in eukaryotes
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The glycosylation design space for recombinant lysosomal replacement enzymes produced in CHO cells
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Display of the human mucinome with defined O-glycans by gene engineered cells
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