Sam Trammell
Special Consultant, Guest Researcher
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
Moritz Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal
2200 København N.
- Published
Clostridium scindens secretome suppresses virulence gene expression of Clostridioides difficile in a bile acid-independent manner
Saenz, C., Fang, Q., Gnanasekaran, Thiyagarajan, Trammell, Sam, Buijink, Jesse A., Pisano, P., Wierer, M., Moens, F., Lengger, B., Brejnrod, A. & Arumugam, Mani, 2023, In: Microbiology Spectrum. 11, 5, p. 1-18 e0393322.Research output: Contribution to journal › Journal article › Research › peer-review
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N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis
Grevengoed, Trisha Jean, Trammell, Sam, McKinney, M. K., Petersen, N., Cardone, R. L., Svenningsen, J. S., Ogasawara, D., Nexøe-Larsen, C. C., Knop, Filip Krag, Schwartz, Thue W., Kibbey, R. G., Cravatt, B. F. & Gillum, M. P., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 49, p. 24770-24778Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An abundant biliary fatty acid metabolite derived from dietary omega-3 polyunsaturated fatty acids regulates triglycerides
Grevengoed, Trisha Jean, Trammell, Sam, Svenningsen, J. S., Makarov, M., Nielsen, Thomas Svava, Jacobsen, Jens Christian Brings, Calder, P. C., Migaud, M. E., Cravatt, B. & Gillum, M. P., 2021, In: Journal of Clinical Investigation. 131, 6, 12 p., e143861.Research output: Contribution to journal › Journal article › Research › peer-review
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Bile acid conjugation deficiency causes hypercholanemia, hyperphagia, islet dysfunction, and gut dysbiosis in mice
Alrehaili, B. D., Lee, M., Takahashi, S., Novak, R., Rimal, B., Boehme, S., Trammell, Sam, Grevengoed, Trisha Jean, Kumar, D., Alnouti, Y., Chiti, K., Wang, X., Patterson, A. D., Chiang, J. Y. L., Gonzalez, F. J. & Lee, Y., 2022, In: Hepatology Communications. 6, 10, p. 2765-2780 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents
Christiansen, Charlotte Bayer, Trammell, Sam, Albrechtsen, Nicolai Jacob Wewer, Schoonjans, K., Albrechtsen, Reidar, Gillum, M. P., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 5, p. G574-G584 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bilio-enteric flow and plasma concentrations of bile acids after gastric bypass and sleeve gastrectomy
Eiken, A., Fuglsang, S., Eiken, M., Svane, M. S., Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hansen, S. H., Trammell, Sam, Svenningsen, J. S., Rehfeld, Jens Frederik, Bojsen-Møller, K. N., Jørgensen, N. B., Holst, Jens Juul, Madsbad, Sten, Madsen, J. L. & Dirkse, C., 2020, In: International Journal of Obesity. 44, p. 1872-1883Research output: Contribution to journal › Journal article › Research › peer-review
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Control of NAD+ homeostasis by autophagic flux modulates mitochondrial and cardiac function
Zhang, Q., Li, Z., Li, Q., Trammell, Sam, Schmidt, M. S., Pires, K. M., Cai, J., Zhang, Y., Kenny, H., Boudina, S., Brenner, C. & Abel, E. D., 2024, In: EMBO Journal. 43, 3, p. 362-390Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity
Heer, C. D., Sanderson, D. J., Voth, L. S., Alhammad, Y. M. O., Schmidt, M. S., Trammell, Sam, Perlman, S., Cohen, M. S., Fehr, A. R. & Brenner, C., 2020, In: Journal of Biological Chemistry. 295, 52, p. 17986-17996 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Discovery and characterization of novel nonsubstrate and substrate NAMPT inhibitors
Wilsbacher, J. L., Cheng, M., Cheng, D., Trammell, S. A. J., Shi, Y., Guo, J., Koeniger, S. L., Kovar, P. J., He, Y., Selvaraju, S., Heyman, H. R., Sorensen, B. K., Clark, R. F., Hansen, T. M., Longenecker, K. L., Raich, D., Korepanova, A. V., Cepa, S., Towne, D. L., Abraham, V. C. & 13 others, , 2017, In: Molecular Cancer Therapeutics. 16, 7, p. 1236-1245 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Divergent effects of resistance and endurance exercise on plasma bile acids, FGF19, and FGF21 in humans
Morville, T., Sahl, Ronni Eg, Trammell, Sam, Svenningsen, J. S., Gillum, M. P., Helge, Jørn Wulff & Clemmensen, Christoffer, 2018, In: JCI Insight. 3, 15, p. 1-13 e122737.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Nicotinamide Riboside on Endocrine Pancreatic Function and Incretin Hormones in Nondiabetic Men With Obesity
Dollerup, O. L., Trammell, Sam, Hartmann, Bolette, Holst, Jens Juul, Christensen, B., Møller, N., Gillum, M. P., Treebak, Jonas Thue & Jessen, N., 1 Nov 2019, In: The Journal of clinical endocrinology and metabolism. 104, 11, p. 5703-5714 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FGF21 suppresses alcohol consumption through an amygdalo-striatal circuit
Flippo, K. H., Trammell, Sam, Gillum, M. P., Aklan, I., Perez, M. B., Yavuz, Y., Smith, N. K., Jensen-Cody, S. O., Zhou, B., Claflin, K. E., Beierschmitt, A., Fink-Jensen, Anders, Knop, Filip Krag, Palmour, R. M., Grueter, B. A., Atasoy, D. & Potthoff, M. J., 2022, In: Cell Metabolism. 34, 2, p. 317-328.e6Research output: Contribution to journal › Journal article › Research › peer-review
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FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest
Søberg, S., Andersen, E. S., Dalsgaard, N. B., Jarlhelt, I., Hansen, N. L., Hoffmann, N., Vilsbøll, Tina, Chenchar, A., Jensen, M., Grevengoed, Trisha Jean, Trammell, Sam, Knop, Filip Krag & Gillum, M. P., 2018, In: Molecular Metabolism. 11, p. 96-103 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus
de Guia, R. M., Hassing, Anna Skab, Skov, Louise Julie, Ratner, C., Plucinska, Kaja, Madsen, S., Diep, T. A., dela Cruz, Gelo, Trammell, Sam, Sustarsic, E. G., Emanuelli, Brice, Gillum, M. P., Gerhart-Hines, Zach, Holst, Birgitte & Treebak, Jonas Thue, 2020, In: Acta Physiologica. 228, 4Research output: Contribution to journal › Journal article › Research › peer-review
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Fibroblast growth factor 21 is the main alcohol responsive peptide hormone in humans and individuals with alcohol use disorder exihibit increased plasma concentrations after alcohol intake
Lanng, A., Gasbjerg, Lærke Smidt, Sucksdorff, A., Svenningsen, J., Trammell, Sam, Vilsbøll, Tina, Gillum, M. & Knop, Filip Krag, 2022, In: Journal of Hepatology. 77, S1, p. S121-S121 1 p., THU006.Research output: Contribution to journal › Conference abstract in journal › Research
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Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis
Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, , 2020, In: Molecular Metabolism. 42, 18 p., 101080.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5
Trammell, Sam, Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P. & Kuhre, Rune Ehrenreich, 2020, In: Molecules. 25, 14 p., 2371.Research output: Contribution to journal › Journal article › Research › peer-review
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Hepatocyte-specific perturbation of NAD+ biosynthetic pathways in mice induces reversible nonalcoholic steatohepatitis-like phenotypes
Dall, M., Hassing, Anna Skab, Niu, Lili, Nielsen, Thomas Svava, Ingerslev, L. R., Sulek, K., Trammell, Sam, Gillum, M. P., Barrès, Romain, Larsen, Steen, Poulsen, Steen Seier, Mann, Matthias, Ørskov, Cathrine & Treebak, Jonas Thue, 2021, In: Journal of Biological Chemistry. 297, 6, 26 p., 101388.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of bile acid-CoA:amino acid N-acyltransferase as the hepatic N-acyl taurine synthase for polyunsaturated fatty acids
Trammell, Sam, Gamon, Luke Francis, Gotfryd, K., Michler, Katja Thorøe, Alrehaili, B. D., Rix, I., Knop, Filip Krag, Gourdon, Pontus Emanuel, Lee, Y. K., Davies, Michael J., Gillum, M. P. & Grevengoed, Trisha Jean, 2023, In: Journal of Lipid Research. 64, 9, 9 p., 100361.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity
Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NNMT: A Bad Actor in Fat Makes Good in Liver
Trammell, Sam & Brenner, C., 4 Aug 2015, In: Cell Metabolism. 22, 2, p. 200-201 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
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NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells
Ratajczak, J., Joffraud, M., Trammell, Sam, Ras, R., Canela, N., Boutant, M., Kulkarni, S. S., Rodrigues, M., Redpath, P., Migaud, M. E., Auwerx, J., Yanes, O., Brenner, C. & Cantó, C., 11 Oct 2016, In: Nature Communications. 7, 13103.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nicotinamide riboside is a major NAD+ precursor vitamin in cow milk
Trammell, Sam, Y., L., Redpath, P., Migaud, M. E. & Brenner, C., 1 May 2016, In: Journal of Nutrition. 146, 5, p. 957-963 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
Trammell, Sam, Schmidt, M. S., Weidemann, B. J., Redpath, P., Jaksch, F., Dellinger, R. W., Li, Z., Abel, E. D., Migaud, M. E. & Brenner, C., 10 Oct 2016, In: Nature Communications. 7, 12948.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nicotinamide riboside opposes type 2 diabetes and neuropathy in mice
Trammell, Sam, Weidemann, B. J., Chadda, A., Yorek, M. S., Holmes, A., Coppey, L. J., Obrosov, A., Kardon, R. H., Yorek, M. A. & Brenner, C., 27 May 2016, In: Scientific Reports. 6, 26933.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 138358551
Most downloads
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249
downloads
Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
150
downloads
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
126
downloads
FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest
Research output: Contribution to journal › Journal article › Research › peer-review
Published