Maiken Nedergaard
Professor
- 1983
- Published
Secondary brain stem hemorrhage in stroke
Nedergaard, Maiken, Klinken, L. & Paulson, Olaf B., 1 Jul 1983, In: Stroke. 14, 4, p. 501-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Contributions of the Na⁺/K⁺-ATPase, NKCC1, and Kir4.1 to hippocampal K⁺ clearance and volume responses
Larsen, B. R., Assentoft, M., Cotrina, M. L., Hua, S. Z., Nedergaard, Maiken, Kaila, K., Voipio, J. & MacAulay, Nanna, Apr 2014, In: Glia. 62, 4, p. 608-22 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism
Lundgaard, I., Li, B., Xie, L., Kang, H., Sanggaard, S., Haswell, J. D. R., Sun, W., Goldman, S., Blekot, S., Nielsen, Michael Lund, Takano, T., Deane, R. & Nedergaard, Maiken, 2015, In: Nature Communications. 6, 12 p., 6807.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implications of the discovery of brain lymphatic pathways
Iliff, J. J., Goldman, Steven Alan & Nedergaard, Maiken, 2015, In: Lancet Neurology. 14, 10, p. 977-979 3 p.Research output: Contribution to journal › Journal article › Communication
- Published
Modeling cognition and disease using human glial chimeric mice
Goldman, Steven Alan, Nedergaard, Maiken & Windrem, M. S., Aug 2015, In: Glia. 63, 8, p. 1483-1493 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Distinct Population of Microglia Supports Adult Neurogenesis in the Subventricular Zone
Ribeiro Xavier, A. L., Kress, B. T., Goldman, Steven Alan, Lacerda de Menezes, J. R. & Nedergaard, Maiken, 26 Aug 2015, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 34, p. 11848-11861 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Glymphatic system
Benveniste, H. & Nedergaard, Maiken, 2016, Neuroscience in the 21st Century: From Basic to Clinical. 2 ed. Springer, p. 1945-1962 18 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Sulforhodamine 101, a widely used astrocyte marker, can induce cortical seizure-like activity at concentrations commonly used
Rasmussen, R., Nedergaard, Maiken & Petersen, Nicolas Caesar, 2016, In: Scientific Reports. 6, 9 p., 30433.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Purinergic receptor P2RY12-dependent microglial closure of the injured blood-brain barrier
Lou, N., Takano, T., Pei, Y., L R Xavier, Anna , Goldman, Steven Alan & Nedergaard, Maiken, 26 Jan 2016, In: National Academy of Sciences. Proceedings. 113, 4, p. 1074-1079 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in the composition of brain interstitial ions control the sleep-wake cycle
Ding, F., O'Donnell, J., Xu, Q., Kang, N., Goldman, N. & Nedergaard, Maiken, 29 Apr 2016, In: Science. 352, 6285, p. 550-555 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human glia can both induce and rescue aspects of disease phenotype in Huntington disease
Benraiss, A., Wang, S., Herrlinger, S., Li, X., Chandler-Militello, D., Mauceri, J., Burm, H. B., Toner, M., Osipovitch, M., Jim Xu, Q., Ding, F., Wang, F., Kang, N., Kang, J., Curtin, P. C., Brunner, D., Windrem, M. S., Munoz-Sanjuan, I., Nedergaard, Maiken & Goldman, Steven Alan, 7 Jun 2016, In: Nature Communications. 7, 13 p., 11758.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The homeostatic astroglia emerges from evolutionary specialization of neural cells
Verkhratsky, A. & Nedergaard, Maiken, 5 Aug 2016, In: Royal Society of London. Philosophical Transactions B. Biological Sciences. 371, 1700, p. 1-11 11 p., 20150428.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erythrocytes Are Oxygen-Sensing Regulators of the Cerebral Microcirculation
Wei, H. S., Kang, H., Rasheed, I. D., Zhou, S., Lou, N., Gershteyn, A., McConnell, E. D., Wang, Y., Richardson, K. E., Palmer, A. F., Xu, C., Wan, J. & Nedergaard, Maiken, 17 Aug 2016, In: Neuron. 91, 4, p. 851-862 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Cerebrospinal fluid clearance in Alzheimer disease measured with dynamic PET
De Leon, M. J., Li, Y., Okamura, N., Tsui, W. H., Saint-Louis, L. A., Glodzik, L., Osorio, R. S., Fortea, J., Butler, T., Pirraglia, E., Fossati, S., Kim, H. J., Carare, R. O., Nedergaard, Maiken, Benveniste, H. & Rusinek, H., 2017, In: Journal of Nuclear Medicine. 58, 9, p. 1471-1476 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SOX9 is an astrocyte-specific nuclear marker in the adult brain outside the neurogenic regions
Sun, W., Cornwell, A., Li, J., Peng, S., Joana Osorio, M., Aalling, Nadia, Wang, S., Benraiss, A., Lou, N., Goldman, Steven Alan & Nedergaard, Maiken, 2017, In: Journal of Neuroscience. 37, 17, p. 4493-4507 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Focal Solute Trapping and Global Glymphatic Pathway Impairment in a Murine Model of Multiple Microinfarcts
Wang, M., Ding, F., Deng, S., Guo, X., Wang, W., Iliff, J. J. & Nedergaard, Maiken, 15 Mar 2017, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 37, 11, p. 2870-2877 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impairment of the glymphatic system after diabetes
Jiang, Q., Zhang, L., Ding, G., Davoodi-Bojd, E., Li, Q., Li, L., Sadry, N., Nedergaard, Maiken, Chopp, M. & Zhang, Z., 1 Apr 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 4, p. 1326-1337 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does Global Astrocytic Calcium Signaling Participate in Awake Brain State Transitions and Neuronal Circuit Function?
Kjærby, Celia, Rasmussen, R., Andersen, Mie & Nedergaard, Maiken, Jun 2017, In: Neurochemical Research. 42, 6, p. 1810-1822 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glymphatic clearance controls state-dependent changes in brain lactate concentration
Lundgaard, I., Lu, M. L., Yang, E., Peng, W., Mestre, H., Hitomi, E., Deane, R. & Nedergaard, Maiken, Jun 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 6, p. 2112-2124 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human iPSC Glial Mouse Chimeras Reveal Glial Contributions to Schizophrenia
Windrem, M. S., Osipovitch, M., Liu, Z., Bates, J., Chandler-Militello, D., Zou, L., Munir, J., Schanz, S., McCoy, K., Miller, R. H., Wang, S., Nedergaard, Maiken, Findling, R. L., Tesar, P. J. & Goldman, Steven Alan, 3 Aug 2017, In: Cell Stem Cell. 21, 2, p. 195-208.e6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain?
Oberheim Bush, N. A. & Nedergaard, Maiken, Sep 2017, In: Neurochemical Research. 42, 9, p. 2577-2587 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perivascular spaces, glymphatic dysfunction, and small vessel disease
Mestre, H., Kostrikov, S., Mehta, R. I. & Nedergaard, Maiken, 1 Sep 2017, In: Clinical Science. 131, 17, p. 2257-2274 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Understanding the functions and relationships of the glymphatic system and meningeal lymphatics
Louveau, A., Plog, B. A., Antila, S., Alitalo, K., Nedergaard, Maiken & Kipnis, J., 1 Sep 2017, In: The Journal of Clinical Investigation. 127, 9, p. 3210-3219 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Brain energetics during the sleep-wake cycle
DiNuzzo, M. & Nedergaard, Maiken, Dec 2017, In: Current Opinion in Neurobiology. 47, p. 65-72 8 p.Research output: Contribution to journal › Review › Research › peer-review
- 2018
- Published
AMELIORATION OF GLYMPHATIC PATHWAY IS CRITICAL FOR LONG TERM RECOVERY FROM TRAUMATIC BRAIN INJURY
Hussain, R., Wang, W., Cheetham-West, A. O., Sun, Q. & Nedergaard, Maiken, 2018, p. A204. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Altered physiological brain variation in drug-resistant epilepsy
Kananen, J., Tuovinen, T., Ansakorpi, H., Rytky, S., Helakari, H., Huotari, N., Raitamaa, L., Raatikainen, V., Rasila, A., Borchardt, V., Korhonen, V., LeVan, P., Nedergaard, Maiken & Kiviniemi, V., 2018, In: Brain and Behavior. 8, 9, p. 1-17 17 p., e01090.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aquaporin-4-dependent glymphatic solute transport in the rodent brain
Mestre, H., Hablitz, L. M., Xavier, A. L. R., Feng, W., Zou, W., Pu, T., Monai, H., Murlidharan, G., Rivera, R. M. C., Simon, M. J., Pike, M. M., Pla, V., Du, T., Kress, B. T., Wang, X., Plog, B. A., Thrane, A. S., Lundgaard, I., Abe, Y., Yasui, M. & 6 others, , 2018, In: eLife. 7, 31 p., :e40070.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function
Lundgaard, I., Wang, W., Eberhardt, A., Vinitsky, H. S., Reeves, B. C., Peng, S., Lou, N., Hussain, R. & Nedergaard, Maiken, 2018, In: Scientific Reports. 8, 1, 16 p., 2246.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brain Segmentation in Rodent MR-Images Using Convolutional Neural Networks
Sigurdsson, B., Darkner, Sune, Sommer, Stefan Horst, Mortensen, K. N., Sanggaard, S., Kostrikov, S. & Nedergaard, Maiken, 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Cannula Implantation into the Cisterna Magna of Rodents
L R Xavier, Anna , Hauglund, Natalie Linea, Holstein-Rønsbo, Stephanie, Li, Q., Sanggaard, S., Lou, N., Lundgaard, I. & Nedergaard, Maiken, 2018, In: Journal of Visualized Experiments. 135, 6 p., e57378.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension
Mestre, H., Tithof, J., Du, T., Song, W., Peng, W., Sweeney, A. M., Olveda, G., Thomas, J. H., Nedergaard, Maiken & Kelley, D. H., 2018, In: Nature Communications. 9, 1, 9 p., 4878.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiology of astroglia
Verkhratsky, A. & Nedergaard, Maiken, 2018, In: Physiological Reviews. 98, 1, p. 239-389 151 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Quantitative Gd-DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA-SPGR at 9.4T
Lee, H., Mortensen, K., Sanggaard, S., Koch, P., Brunner, H., Quistorff, B., Nedergaard, Maiken & Benveniste, H., 2018, In: Magnetic Resonance in Medicine. 79, 3, p. 1568-1578 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glymphatic pathway in neurological disorders
Rasmussen, Martin Kaag, Mestre, H. & Nedergaard, Maiken, 2018, In: The Lancet Neurology. 17, 11, p. 1016-1024 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Understanding the role of the perivascular space in cerebral small vessel disease
Brown, R., Benveniste, H., Black, S. E., Charpak, S., Dichgans, M., Joutel, A., Nedergaard, Maiken, Smith, K. J., Zlokovic, B. V. & Wardlaw, J. M., 2018, In: Cardiovascular Research. 114, 11, p. 1462-1473 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Voluntary running enhances glymphatic influx in awake behaving, young mice
Holstein-Rønsbo, Stephanie, Petersen, Nicolas Caesar & Nedergaard, Maiken, 2018, In: Neuroscience Letters. 662, p. 253-258 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebral Metabolic Changes During Sleep
Aalling, Nadia, Nedergaard, Maiken & DiNuzzo, M., 1 Sep 2018, In: Current Neurology and Neuroscience Reports. 18, 9, 17 p., 57.Research output: Contribution to journal › Review › Research › peer-review
- 2019
- Published
Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke
Monai, H., Wang, X., Yahagi, K., Lou, N., Mestre, H., Xu, Q., Abe, Y., Yasui, M., Iwai, Y., Nedergaard, Maiken & Hirase, Hajime, 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 22, p. 11010-11019 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Astrocytes in chronic pain and itch
Ji, R., Donnelly, C. R. & Nedergaard, Maiken, 2019, In: Nature Reviews Neuroscience. 20, 11, p. 667-685Research output: Contribution to journal › Review › Research › peer-review
- Published
Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease
Wang, M., Qin, C., Luo, X., Wang, J., Wang, X., Xie, M., Hu, J., Cao, J., Hu, T., Goldman, Steven Alan, Nedergaard, Maiken & Wang, W., 2019, In: Theranostics. 9, 15, p. 4474-4493 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brain Morphometry and Longitudinal Relaxation Time of Spontaneously Hypertensive Rats (SHRs) in Early and Intermediate Stages of Hypertension Investigated by 3D VFA-SPGR MRI
Koundal, S., Liu, X., Sanggaard, S., Mortensen, K., Wardlaw, J., Nedergaard, Maiken, Benveniste, H. & Lee, H., 2019, In: Neuroscience. 404, p. 14-26Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas
Grutzendler, J. & Nedergaard, Maiken, 2019, In: Trends in Neurosciences. 42, 8, p. 528-536 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Cisterna magna injection in rats to study glymphatic function
Ramos, M., Burdon Bechet, N., Battistella, R., Pavan, C., L R Xavier, Anna , Nedergaard, Maiken & Lundgaard, I., 2019, Astrocytes: Methods and Protocols. Di Benedetto, B. (ed.). Humana Press, p. 97-104 8 p. (Methods in Molecular Biology, Vol. 1938).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Cortex-wide Changes in Extracellular Potassium Ions Parallel Brain State Transitions in Awake Behaving Mice
Rasmussen, R., Nicholas, E., Petersen, Nicolas Caesar, Dietz, Andrea Grostøl, Xu, Q., Sun, Q. & Nedergaard, Maiken, 2019, In: Cell Reports. 28, 5, p. 1182-1194 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs
Lilius, T. O., Blomqvist, K., Hauglund, Natalie Linea, Liu, G., Stæger, Frederik Filip Vinggaard, Baerentzen, S., Du, T., Ahlstrom, F., Backman, J. T., Kalso, E. A., Rauhala, P. V. & Nedergaard, Maiken, 2019, In: Journal of Controlled Release. 304, p. 29-38 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling
Liu, Z., Osipovitch, M., Benraiss, A., Huynh, N. P. T., Foti, R., Bates, J., Chandler-Militello, D., Findling, R. L., Tesar, P. J., Nedergaard, Maiken, Windrem, M. S. & Goldman, Steven Alan, 2019, In: Cell Reports. 27, 13, p. 3832-3843, e1-e6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EARLY ADDRESS OF POST-TRAUMATIC GLYMPHATIC INSUFFICIENCY REDUCES NEURONAL/GLIAL CELL DEATH AND TISSUE DAMAGES
Hussain, R., Wang, W. & Nedergaard, Maiken, 2019, In: Journal of Neurotrauma. 36, 13, p. A-101 1 p., B04-05.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Genetic haplotype of the glymphatic-associated water channel aquaporin 4 modulates slow waves in human non-rapid eye movement sleep
Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., 2019, In: European Neuropsychopharmacology. 29, Supplement 6, p. S563-S564 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Impaired Glymphatic Transport in Spontaneously Hypertensive Rats
Nygaard Mortensen, K., Sanggaard, S., Mestre, H., Lee, H., Kostrikov, S., L R Xavier, Anna , Gjedde, Albert, Benveniste, H. & Nedergaard, Maiken, 2019, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 32, p. 6365-6377 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy
Sweeney, A. M., Pla, V., Du, T., Liu, G., Sun, Q., Peng, S., Plog, B. A., Kress, B. T., Wang, X., Mestre, H. & Nedergaard, Maiken, 2019, In: Journal of Visualized Experiments. 149, 7 p., e59774.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia
Hablitz, L. M., Vinitsky, H. S., Sun, Q., Stæger, Frederik Filip Vinggaard, Sigurdsson, B., Mortensen, K. N., Lilius, T. O. & Nedergaard, Maiken, 2019, In: Science Advances. 5, 2, 9 p., eaav5447.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PDGF-B Is Required for Development of the Glymphatic System
Munk, A. S., Wang, W., Bèchet, N. B., Eltanahy, A. M., Cheng, A. X., Sigurdsson, B., Benraiss, A., Mäe, M. A., Kress, B. T., Kelley, D. H., Betsholtz, C., Møllgård, Kjeld, Meissner, A., Nedergaard, Maiken & Lundgaard, I., 2019, In: Cell Reports. 26, 11, p. 2955-2969.e3 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections
Cai, R., Pan, C., Ghasemigharagoz, A., Todorov, M. I., Foerstera, B., Zhao, S., Bhatia, H. S., Parra-Damas, A., Mrowka, L., Theodorou, D., Rempfler, M., Xavier, A. L. R., Kress, B. T., Benakis, C., Steinke, H., Liebscher, S., Bechmann, I., Liesz, A., Menze, B., Kerschensteiner, M. & 2 others, , 2019, In: Nature Neuroscience. 22, 2, p. 317-327Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SPECT imaging of the glymphatic pathway with In-111-labeled ovalbumin in the rat brain
Shalgunov, Vladimir, Lilius, T., Sigurosson, B., Baerentzen, S. L., Hauglund, Natalie Linea, Herth, Matthias Manfred, Palner, M. & Nedergaard, Maiken, 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supplement 1, p. S404-S405 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
State-Dependent Changes in Brain Glycogen Metabolism
DiNuzzo, M., Walls, Anne Byriel, Öz, G., Seaquist, E. R., Waagepetersen, Helle S., Bak, Lasse Kristoffer, Nedergaard, Maiken & Schousboe, Arne, 2019, Brain Glycogen Metabolism. DiNuzzo, M. & Schousboe, A. (eds.). Springer, p. 269-309 41 p. (Advances in Neurobiology, Vol. 23).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The glymphatic system: reactive gliosis as a negative regulator
Nedergaard, Maiken, 2019, In: Glia. 67, S1, p. E91 1 p., S26-02.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Vascular dysfunction-The disregarded partner of Alzheimer's disease
Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., Jacobs, R. E., Doubal, F. N., Ramirez, J., Black, S. E., Nedergaard, M., Benveniste, H., Dichgans, M., Iadecola, C., Love, S., Bath, P. M. & 49 others, , 2019, In: Alzheimers & Dementia. 15, 1, p. 158-167Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ocular Glymphatic Clearance System
Wang, X., Lou, N., Eberhardt, A., Jørgensen, P. K., Xu, Q., Foerstera, B., Peng, S., Yang, Y., Shi, M., L R Xavier, Anna , Ertürk, A., Libby, R. T., Lu, C., Thrane, A. & Nedergaard, Maiken, 30 Dec 2019, bioRxiv, 23 p.Research output: Working paper › Preprint › Research
- 2020
- Published
A three-dimensional, population-based average of the C57BL/6 mouse brain from DAPI-stained coronal slices
Stæger, Frederik Filip Vinggaard, Mortensen, K. N., Nielsen, M. S. N., Sigurdsson, B., Kaufmann, L. K., Hirase, Hajime & Nedergaard, Maiken, 2020, In: Scientific Data. 7, 1, 7 p., 235.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An ocular glymphatic clearance system removes beta-amyloid from the rodent eye
Wang, X., Lou, N., Eberhardt, A., Yang, Y., Kusk, P., Xu, Q., Forstera, B., Peng, S., Shi, M., Ladron-de-Guevara, A., Delle, Christine, Sigurdsson, B., L R Xavier, Anna , Erturk, A., Libby, R. T., Chen, L., Thrane, A. S. & Nedergaard, Maiken, 2020, In: Science Translational Medicine. 12, 536, eaaw3210.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aquaporin 1 and the Na+/K+/2Cl- cotransporter 1 are present in the leptomeningeal vasculature of the adult rodent central nervous system
Li, Q., Aalling, Nadia, Förstera, B., Ertürk, A., Nedergaard, Maiken, Møllgård, Kjeld & L R Xavier, Anna , 2020, In: Fluids and Barriers of the CNS. 17, 15 p., 15.Research output: Contribution to journal › Journal article › Research › peer-review
Astrocytic Endocannabinoids Mediate Hippocampal Transient Heterosynaptic Depression
Smith, N. A., Bekar, L. K. & Nedergaard, Maiken, 2020, In: Neurochemical Research. 45, 1, p. 100-108 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biological sex does not predict glymphatic influx in healthy young, middle aged or old mice
Giannetto, M., Xia, M., Stæger, Frederik Filip Vinggaard, Metcalfe, T., Vinitsky, H. S., Dang, J. A. M. L., L R Xavier, Anna , Kress, B. T., Nedergaard, Maiken & Hablitz, L. M., 2020, In: Scientific Reports. 10, 1, 8 p., 16073.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebrospinal fluid influx drives acute ischemic tissue swelling
Mestre, H., Du, T., Sweeney, A. M., Liu, G., Samson, A. J., Peng, W., Mortensen, K. N., Stæger, F. F., Bork, P. A. R., Bashford, L., Toro, E. R., Tithof, J., Kelley, D. H., Thomas, J. H., Hjorth, P. G., Martens, E. A., Mehta, R. I., Solis, O., Blinder, P., Kleinfeld, D. & 3 others, , 2020, In: Science. 367, 6483, 8 p., eaaw7462.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circadian control of brain glymphatic and lymphatic fluid flow
Hablitz, L. M., Plá, V., Giannetto, M., Vinitsky, H. S., Stæger, Frederik Filip Vinggaard, Metcalfe, T., Nguyen, R., Benrais, A. & Nedergaard, Maiken, 2020, In: Nature Communications. 11, 1, 4411.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Defining novel functions for cerebrospinal fluid in ALS pathophysiology
Ng Kee Kwong, K. C., Mehta, A. R., Nedergaard, Maiken & Chandran, S., 2020, In: Acta Neuropathologica Communications. 8, 1, 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Direct Measurement of Cerebrospinal Fluid Production in Mice
Liu, G., Mestre, H., Sweeney, A. M., Sun, Q., Weikop, Pia, Du, T. & Nedergaard, Maiken, 2020, In: Cell Reports. 33, 12, 13 p., 108524.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Editorial: Sleep and Mood Disorders
Verkhratsky, A., Nedergaard, Maiken, Steardo, L. & Li, B., 2020, In: Frontiers in Psychiatry. 10, 3 p., 981.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Glial cells in schizophrenia: a unified hypothesis
Dietz, Andrea Grostøl, Goldman, Steven Alan & Nedergaard, Maiken, 2020, In: Lancet Psychiatry. 7, 3, p. 272-281 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus
Reeves, B. C., Karimy, J. K., Kundishora, A. J., Mestre, H., Cerci, H. M., Matouk, C., Alper, S. L., Lundgaard, I., Nedergaard, Maiken & Kahle, K. T., 2020, In: Trends in Molecular Medicine. 26, 3, p. 285-295 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glymphatic failure as a final common pathway to dementia
Nedergaard, Maiken & Goldman, Steven Alan, 2020, In: Science (New York, N.Y.). 370, 6512, p. 50-56 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Human Glial Progenitor Cells Effectively Remyelinate the Demyelinated Adult Brain
Windrem, M. S., Schanz, S. J., Zou, L., Chandler-Militello, D., Kuypers, N. J., Nedergaard, Maiken, Lu, Y., Mariani, J. N. & Goldman, Steven Alan, 2020, In: Cell Reports. 31, 7, 23 p., 107658.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets
Karimy, J. K., Reeves, B. C., Damisah, E., Duy, P. Q., Antwi, P., David, W., Wang, K., Schiff, S. J., Limbrick, D. D. ,. J., Alper, S. L., Warf, B. C., Nedergaard, Maiken, Simard, J. M. & Kahle, K. T., 2020, In: Nature Reviews Neurology. 16, p. 285–296 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Interstitial ions: A key regulator of state-dependent neural activity?
Rasmussen, R., O'Donnell, J., Ding, F. & Nedergaard, Maiken, 2020, In: Progress in Neurobiology. 98, 101802.Research output: Contribution to journal › Review › Research › peer-review
- Published
Meningeal Lymphangiogenesis and Enhanced Glymphatic Activity in Mice with Chronically Implanted EEG Electrodes
Hauglund, Natalie Linea, Kusk, P., Kornum, Birgitte Rahbek & Nedergaard, Maiken, 2020, In: Journal of Neuroscience. 40, 11, p. 2371-2380 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System
Kounda, S., Elkin, R., Nadeem, S., Xue, Y., Constantinou, S., Sanggaard, S., Liu, X., Monte, B., Xu, F., Van Nostrand, W., Nedergaard, Maiken, Lee, H., Wardlaw, J., Benveniste, H. & Tannenbaum, A., 2020, In: Scientific Reports. 10, 1, 18 p., 1990.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perivascular spaces in the brain: anatomy, physiology and pathology
Wardlaw, J. M., Benveniste, H., Nedergaard, Maiken, Zlokovic, B. V., Mestre, H., Lee, H., Doubal, F. N., Brown, R., Ramirez, J., MacIntosh, B. J., Tannenbaum, A., Ballerini, L., Rungta, R. L., Boido, D., Sweeney, M., Montagne, A., Charpak, S., Joutel, A., Smith, K. J. & Black, S. E., 2020, In: Nature Reviews. Neurology. 16, p. 137-153 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Respiratory-related brain pulsations are increased in epilepsy-a two-centre functional MRI study
Kananen, J., Helakari, H., Korhonen, V., Huotari, N., Jarvela, M., Raitamaa, L., Raatikainen, V., Rajna, Z., Tuovinen, T., Nedergaard, Maiken, Jacobs, J., LeVan, P., Ansakorpi, H. & Kiviniemi, V., 2020, In: Brain Communications. 2, 2, 14 p., 076.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surface periarterial spaces of the mouse brain are open, not porous
Min Rivas, F., Liu, J., Martell, B. C., Du, T., Mestre, H., Nedergaard, Maiken, Tithof, J., Thomas, J. H. & Kelley, D. H., 2020, In: Journal of the Royal Society, Interface. 17, 172, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Brain's Glymphatic System: Current Controversies
Mestre, H., Mori, Yuki & Nedergaard, Maiken, 2020, In: Trends in Neurosciences. 43, 7, p. 458-466 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Glymphatic System and Pain
Goldman, N., Hablitz, L. M., Mori, Yuki & Nedergaard, Maiken, 2020, In: Medical Acupuncture. 32, 6, p. 373-376 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
When the air hits your brain: Decreased arterial pulsatility after craniectomy leading to impaired glymphatic flow
Plog, B. A., Lou, N., Pierre, C. A., Cove, A., Kenney, H. M., Hitomi, E., Kang, H., Iliff, J. J., Zeppenfeld, D. M., Nedergaard, Maiken & Vates, G. E., 2020, In: Journal of Neurosurgery. 133, 1, p. 210-223 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Haplotype of the astrocytic water channel AQP4 is associated with slow wave energy regulation in human NREM sleep
Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., May 2020, In: PLOS Biology. 18, 5, 14 p., e3000623.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cleaning the sleeping brain – the potential restorative function of the glymphatic system
Hauglund, Natalie Linea, Pavan, C. & Nedergaard, Maiken, 1 Jun 2020, In: Current Opinion in Physiology. 15, 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic fluctuations of the locus coeruleus-norepinephrine system underlie sleep state transitions
Kjærby, Celia, Andersen, Mie, Hauglund, Natalie Linea, Ding, F., Wang, W., Xu, Q., Deng, S., Kang, N., Peng, S., Sun, Q., Dall, C., Jørgensen, P. K., Feng, J., Li, Y., Weikop, Pia, Hirase, Hajime & Nedergaard, Maiken, 2 Sep 2020, 1 p.Research output: Other contribution › Research
- 2021
- Published
Adrenergic inhibition facilitates normalization of extracellular potassium after cortical spreading depolarization
Monai, H., Koketsu, S., Shinohara, Y., Ueki, T., Kusk, P., Hauglund, Natalie Linea, Samson, A. J., Nedergaard, Maiken & Hirase, Hajime, 2021, In: Scientific Reports. 11, 1, 8150.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection
Raghunandan, A., Ladron-De-guevara, A., Tithof, J., Mestre, H., Du, T., Nedergaard, Maiken, Thomas, J. H. & Kelley, D. H., 2021, In: eLife. 10, 15 p., e65958.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CSF space volumetry using 3D-CISS in Aqp4-deficient mice – quantitative analysis and technical advances
Gomolka, Ryszard Stefan, Nedergaard, Maiken & Mori, Yuki, 2021, Book of Abstracts ESMRMB 2021 Online 38th Annual Scientific Meeting 7-9 October 2021. Springer, Vol. 34. p. S95-6 2 p. (Magnetic Resonance Materials in Physics, Biology, and Medicine; No. 34).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Cardiovascular brain impulses in Alzheimer's disease
Rajna, Z., Mattila, H., Huotari, N., Tuovinen, T., Krüger, J., Holst, S. C., Korhonen, V., Remes, A. M., Seppänen, T., Hennig, J., Nedergaard, Maiken & Kiviniemi, V., 2021, In: Brain. 144, 7, p. 2214-2226 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebral small vessel disease: A glymphopathy?
Benveniste, H. & Nedergaard, Maiken, 2021, In: Current Opinion in Neurobiology. 72, p. 15-21 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Changes in visual processing during progression of Tau accumulation and neurodegeneration in a mouse model of human tauopathy
Parka, A., Nedergaard, Maiken, Sotty, F. & Laursen, B., 2021, In: Investigative Ophthalmology & Visual Science. 62, 8, 3 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
DNase treatment prevents CSF block in early experimental pneumococcal meningitis
Pavan, C., L R Xavier, Anna , Ramos, M., Fisher, J., Kritsilis, M., Linder, A., Bentzer, P., Nedergaard, Maiken & Lundgaard, I., 2021, In: Annals of Neurology. 90, 4, p. 653-669 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inverse correlation of fluctuations of cerebral blood and water concentrations in humans
Borchardt, V., Korhonen, V., Helakari, H., Nedergaard, Maiken, Myllylä, T. & Kiviniemi, V., 2021, In: European Physical Journal Plus. 136, 5, 497.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping of CSF transport using high spatiotemporal resolution dynamic contrast-enhanced MRI in mice: Effect of anesthesia
Stanton, E. H., Persson, N. D. Å., Gomolka, Ryszard Stefan, Lilius, T., Sigurðsson, B., Lee, H., L R Xavier, Anna , Benveniste, H., Nedergaard, Maiken & Mori, Yuki, 2021, In: Magnetic Resonance in Medicine. 85, 6, p. 3326-3342 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NREM sleep upregulates human brain pulsation detected by Ultrafast Magnetic Resonance Encephalography
Larsen, S. M. U., Holst, S. C., Olsen, A. S., Zilstorff, D. B., Pleinert, S., Kiviniemi, V., Jennum, Poul, Nedergaard, Maiken & Knudsen, Gitte Moos, 2021, In: European Neuropsychopharmacology. 53, p. S361-S362 3 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Not All Lectins Are Equally Suitable for Labeling Rodent Vasculature
Battistella, R., Kritsilis, M., Matuskova, H., Haswell, D., Cheng, A. X., Meissner, A., Nedergaard, Maiken & Lundgaard, I., 2021, In: International Journal of Molecular Sciences (Online). 22, 21, 11554.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to: Rethink the classical view of cerebrospinal fluid production
Wardlaw, J. M., Benveniste, H., Nedergaard, Maiken, Zlokovic, B. V., Charpak, S., Smith, K. J. & Black, S. E., 2021, In: Nature Reviews Neurology. 17, 9, p. 590-591Research output: Contribution to journal › Letter › Research › peer-review
- Published
The Glymphatic System (En)during Inflammation
Mogensen, F. L., Delle, Christine & Nedergaard, Maiken, 2021, In: International Journal of Molecular Sciences. 22, 14, 20 p., 7491.Research output: Contribution to journal › Review › Research › peer-review
- Published
The glymphatic system: A novel component of fundamental neurobiology
Hablitz, L. M. & Nedergaard, Maiken, 2021, In: Journal of Neuroscience. 41, 37, p. 7698-7711 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Twists and turns of ocular glymphatic clearance – new study reveals surprising findings in glaucoma
Rangroo Thrane, V., Hynnekleiv, L., Wang, X., Thrane, A. S., Krohn, J. & Nedergaard, Maiken, 2021, In: Acta Ophthalmologica. 99, 2, p. e283-e284 2 p.Research output: Contribution to journal › Letter › Research › peer-review
ID: 101366876
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SPECT imaging of the glymphatic pathway with In-111-labeled ovalbumin in the rat brain
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473
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In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy
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Understanding the functions and relationships of the glymphatic system and meningeal lymphatics
Research output: Contribution to journal › Review › Research › peer-review
Published