Kristian Strømgaard

Kristian Strømgaard

Professor

ORCID: 0000-0003-2206-4737

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  1. Published

    Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity

    Rem, P. D., Sereikaité, Vita, Fernandez-Fernandez, D., Reinartz, S., Ulrich, D., Fritzius, T., Trovò, L., Roux, S., Chen, Ziyang, Rondard, P., Pin, J. P., Schwenk, J., Fakler, B., Gassmann, M., Barkat, T. R., Strømgaard, Kristian & Bettler, B., 2023, In: eLife. 12, 26 p., e82082.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Targeting receptor complexes: a new dimension in drug discovery

    Rosenbaum, M. I., Clemmensen, L. S., Bredt, D. S., Bettler, B. & Strømgaard, Kristian, 2020, In: Nature Reviews. Drug Discovery. 19, p. 884-901 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Knockin mouse with mutant Gα11 mimics human inherited hypocalcemia and is rescued by pharmacologic inhibitors

    Roszko, K. L., Bi, R., Gorvin, C. M., Bräuner, Hans, Xiong, X., Inoue, A., Thakker, R. V., Strømgaard, Kristian, Gardella, T. & Mannstadt, M., 9 Feb 2017, In: JCI insight. 2, 3, 15 p., e91079.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Targeting the gamma-Aminobutyric Acid Type B (GABA(B)) Receptor Complex: Development of Inhibitors Targeting the K+ Channel Tetramerization Domain (KCTD) Containing Proteins/GABA(B) Receptor Protein-Protein Interaction

    Sereikaité, Vita, Fritzius, T., Kasaragod, V. B., Bader, N., Maric, H. M., Schindelin, H., Bettler, B. & Strømgaard, Kristian, 2019, In: Journal of Medicinal Chemistry. 62, 19, p. 8819-8830

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Probing Backbone Hydrogen Bonds in Proteins by Amide-to-Ester Mutations

    Sereikaité, Vita, Jensen, T. M. T., Bartling, Christian Reinhard Otto, Jemth, P., Pless, Stephan & Strømgaard, Kristian, 18 Oct 2018, In: ChemBioChem. 19, 20, p. 2136-2145

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats

    Sommer, J. B., Bach, Anders, Rytter, Hana Malá, Strømgaard, Kristian, Mogensen, J. & Pickering, Darryl S, Oct 2017, In: Pharmacology, Biochemistry and Behavior. 161, p. 62-67 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    In vitro and in vivo effects of a novel dimeric inhibitor of PSD‐95 on excitotoxicity and functional recovery after experimental traumatic brain injury

    Sommer, J. B., Bach, Anders, Rytter, Hana Malá, Strømgaard, Kristian, Mogensen, J. & Pickering, Darryl S, 20 Jan 2017, In: European Journal of Neuroscience. 45, 2, p. 238-248 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Effects of dimeric PSD-95 inhibition on excitotoxic cell death and outcome after controlled cortical impact in rats: PSD-95 inhibition in experimental TBI

    Sommer, J. B., Bach, Anders, Rytter, Hana Malá, Gynther, M., Bjerre, A., Gram, M. G., Marschner, L., Strømgaard, Kristian, Mogensen, J. & Pickering, Darryl S, 2017, In: Neurochemical Research. 42, 12, p. 3401-3413 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Analogues of neuroactive polyamine wasp toxins that lack inner basic sites exhibit enhanced antagonism toward a muscle-type mammalian nicotinic acetylcholine receptor

    Strømgaard, Kristian, Brierley, M. J., Andersen, K., Sløk, F. A., Mellor, I. R., Usherwood, P. N., Krogsgaard-Larsen, Povl & Jaroszewski, J. W., 16 Dec 1999, In: Journal of Medicinal Chemistry. 42, 25, p. 5224-5234 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Site-specific incorporation of unnatural amino acids into proteins

    Strømgaard, A., Jensen, Anders A. & Strømgaard, Kristian, 2004, In: ChemBioChem. 5, 7, p. 909-16 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Recent advances in the medicinal chemistry of polyamine toxins

    Strømgaard, Kristian, Andersen, K., Krogsgaard-Larsen, Povl & Jaroszewski, J. W., Nov 2001, In: Mini - Reviews in Medicinal Chemistry. 1, 4, p. 317-338 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Solid-phase synthesis and biological evaluation of a combinatorial library of philanthotoxin analogues

    Strømgaard, Kristian, Brier, T. J., Andersen, K., Mellor, I. R., Saghyan, A., Tikhonov, D., Usherwood, P. N., Krogsgaard-Larsen, Povl & Jaroszewski, J. W., 16 Nov 2000, In: Journal of Medicinal Chemistry. 43, 23, p. 4526-4533 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Solid phase synthesis and biological evaluation of enantiomerically pure wasp toxin analogues PhTX-343 and PhTX-12

    Strømgaard, Kristian, Bjørnsdottir, I., Andersen, K., Brierley, M. J., Rizoli, S., Eldursi, N., Mellor, I. R., Usherwood, P. N., Hansen, S. H., Krogsgaard-Larsen, Povl & Jaroszewski, J. W., Feb 2000, In: Chirality. 12, 2, p. 93-102 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Giftstoffer fra hvepse og edderkopper i forskning og lægemiddeludvikling

    Strømgaard, Kristian, 2008, In: Carlsbergfondet. Aarsskrift. p. 42-47

    Research output: Contribution to journal › Journal article › Communication

  15. Published

    Polyamine toxins: development of selective ligands for ionotropic receptors

    Strømgaard, Kristian, Jensen, L. S. & Vogensen, S. B., 1 Mar 2005, In: Toxicon. 45, 3, p. 249-254 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Chemistry and biology of terpene trilactones from Ginkgo biloba

    Strømgaard, Kristian & Nakanishi, K., 19 Mar 2004, In: Angewandte Chemie International Edition. 43, 13, p. 1640-1658 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Preparation of a tritiated ginkgolide

    Strømgaard, Kristian, Suehiro, M. & Nakanishi, K., 15 Nov 2004, In: Bioorganic & Medicinal Chemistry Letters. 14, 22, p. 5673-5675 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A heteromeric snake toxin and the molecular details of pain perception

    Strømgaard, Kristian & Kristensen, Anders Skov, 23 Apr 2012, In: Angewandte Chemie International Edition. 51, 17, p. 4009-4011

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Synthesis of polyamines and polyamine toxins. An improved alkylation procedure

    Strømgaard, Kristian & Andersen, T., 2004, In: Tetrahedron Letters. 45, p. 7929-7933

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Chemical biology

    Strømgaard, Kristian, 2010, Textbook of drug design and discovery. Krogsgaard-Larsen, P., Strømgaard, K. & Madsen, U. (eds.). 4 ed. Boca Raton: CRC Press, p. 59-74

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  21. Published

    Fatty acid derivatives of dimeric inhibitors of PSD-95

    Strømgaard, Kristian, Bach, Anders & Nissen, K. B., 4 Jun 2015, IPC No. A61K38/17 , Patent No. WO2015/078477A1, Priority date 1 Dec 2013, Priority No. DK/2013/70735

    Research output: Patent

  22. Published

    Natural products as tools for studies of ligand-gated ion channels

    Strømgaard, Kristian, 2005, In: Chemical Record. 5, 4, p. 229-239 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Protolytic properties of polyamine wasp toxin analogues studied by 13C NMR spectroscopy

    Strømgaard, Kristian, Piazzi, L., Olsen, Christian Adam, Franzyk, Henrik & Jaroszewski, J. W., 2006, In: Magnetic Resonance in Chemistry. 44, 11, p. 1013-22 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A versatile method for solid phase synthesis of polyamines: neuroactive polyamine toxins as example

    Strømgaard, Kristian, Andersen, K., Ruhland, T., Krogsgaard-Larsen, Povl & Jaroszewski, J. W., 2001, In: Synthesis. 6, p. 877-884 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Skræddersyede proteiner: uden naturens begrænsninger

    Strømgaard, Kristian, Jensen, M. S. & Kristensen, Anders Skov, 2009, In: Lægemiddelforskning. p. 10-12

    Research output: Contribution to journal › Journal article › Communication

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