Kristian Strømgaard
Professor
Biopharmaceuticals
Jagtvej 162
2100 København Ø
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Design, synthesis, and pharmacological characterization of polyamine toxin derivatives: potent ligands for the pore-forming region of AMPA receptors
Jensen, L. S., Bølcho, U., Egebjerg, J. & Strømgaard, Kristian, Apr 2006, In: ChemMedChem. 1, 4, p. 419-428 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expressed protein ligation of ionotropic glutamate receptors
Jensen, M. S., Kristensen, Anders Skov & Strømgaard, Kristian, 2007, In: Biopolymers. 88, 4, p. 602Research output: Contribution to journal › Conference abstract in journal › Research
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Probing the Mint2 Protein-Protein Interaction Network Relevant to the Pathophysiology of Alzheimer's Disease
Jensen, T. M. T., Albertsen, L., Bartling, Christian Reinhard Otto, Haugaard-kedström, L. M. & Strømgaard, Kristian, 2018, In: ChemBioChem. 19, 11, p. 1119-1122 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular Details of a Coupled Binding and Folding Reaction between the Amyloid Precursor Protein and a Folded Domain
Jensen, T. M. T., Bartling, Christian Reinhard Otto, Karlsson, O. A., Åberg, E., Haugaard-Kedström, L. M., Strømgaard, Kristian & Jemth, P., 2021, In: ACS chemical biology. 16, 7, p. 1191-1200Research output: Contribution to journal › Journal article › Research › peer-review
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Subunit-Dependent Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Philanthotoxins
Kachel, H. S., Franzyk, Henrik, Strømgaard, Kristian, Tikhonov, D. B. & Mellor, I. R., 28 Jan 2014, In: Biophysical Society. Annual Meeting. Abstracts. 106, 2, p. 338A-338A 1 p.Research output: Contribution to journal › Journal article › Research
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Chemical Synthesis of PDZ Domains
Kossmann, C., Ma, S., Clemmensen, L. S. & Strømgaard, Kristian, 2021, Methods in Molecular Biology. J-P. B. (ed.). Humana Press, p. 193-216 24 p. (Methods in Molecular Biology, Vol. 2256).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation
Kristensen, Anders Skov, Andersen, J., Jørgensen, T. N., Sørensen, L., Eriksen, J., Loland, Claus Juul, Strømgaard, Kristian & Gether, Ulrik, 1 Sep 2011, In: Pharmacological Reviews. 63, 3, p. 585-640 56 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Conjugation of Therapeutic PSD-95 Inhibitors to the Cell-Penetrating Peptide Tat Affects Blood-Brain Barrier Adherence, Uptake, and Permeation
Kristensen, Mie, Kucharz, Krzysztof, Alves Fernandes, Eduardo Felipe, Strømgaard, Kristian, Schallburg Nielsen, M., Cederberg Helms, H. C., Bach, Anders, Ulrikkaholm Tofte-Hansen, M., Aldana, Blanca, Lauritzen, Martin & Larsen, Birger Brodin, 2020, In: Pharmaceutics. 12, 7, 24 p., 661.Research output: Contribution to journal › Journal article › Research › peer-review
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Textbook of drug design and discovery
Krogsgaard-Larsen, Povl, Strømgaard, Kristian & Madsen, Ulf, 2010, 4 ed. Boca Raton: CRC Press. 460 p.Research output: Book/Report › Book › Education
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Solid-phase synthesis of polyamine toxin analogues: potent and selective antagonists of Ca2+-permeable AMPA receptors
Kromann, H., Krikstolaityte, S., Andersen, A. J., Andersen, K., Krogsgaard-Larsen, Povl, Jaroszewski, J. W., Egebjerg, J. & Strømgaard, Kristian, 19 Dec 2002, In: Journal of Medicinal Chemistry. 45, 26, p. 5745-5754 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PSD-95 uncoupling from NMDA receptors by Tat-N-dimer ameliorates neuronal depolarization in cortical spreading depression
Kucharz, Krzysztof, Søndergaard Rasmussen, I., Bach, Anders, Strømgaard, Kristian & Lauritzen, Martin, 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1820-1828Research output: Contribution to journal › Journal article › Research › peer-review
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Facilitating the structural characterisation of non-canonical amino acids in biomolecular NMR
Kuschert, S., Stroet, M., Chin, Y. K. Y., Conibear, A. C., Jia, X., Lee, T., Bartling, Christian Reinhard Otto, Strømgaard, Kristian, Güntert, P., Rosengren, K. J., Mark, A. E. & Mobli, M., 2023, In: Magnetic Resonance. 4, 1, p. 57-72Research output: Contribution to journal › Journal article › Research › peer-review
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A Novel Glycine Receptor Variant with Startle Disease Affects Syndapin I and Glycinergic Inhibition
Langlhofer, G., Schaefer, N., Maric, H. M., Keramidas, A., Zhang, Y., Baumann, P., Blum, R., Breitinger, U., Strømgaard, Kristian, Schlosser, A., Kessels, M. M., Koch, D., Qualmann, B., Breitinger, H. G., Lynch, J. W. & Villmann, C., 2020, In: Journal of Neuroscience. 40, 25, p. 4954-4969 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-activity relationship studies of citalopram derivatives: examining substituents conferring selectivity for the allosteric site in the serotonin transporter
Larsen, M. A. B., Plenge, P., Andersen, J., Eildal, J. N. N., Kristensen, Anders Skov, Bøgesø, K. P., Gether, Ulrik, Strømgaard, Kristian, Bang-Andersen, B. & Loland, Claus Juul, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 925-936 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterotrimeric G Proteins as Therapeutic Targets in Drug Discovery
Li, J., Ge, Y., Huang, J., Strømgaard, Kristian, Zhang, X. & Xiong, X., 2020, In: Journal of Medicinal Chemistry. 63, 10, p. 5013-5030 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Syntenin Inhibitor Blocks Endosomal Entry of SARS-CoV-2 and a Panel of RNA Viruses
Lindqvist, R., Benz, C., Sereikaité, Vita, Maassen, L., Laursen, L., Jemth, P., Strømgaard, Kristian, Ivarsson, Y. & Overby, A. K., 2022, In: Viruses. 14, 10, 12 p., 2202.Research output: Contribution to journal › Journal article › Research › peer-review
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General synthesis of β-alanine-containing spider polyamine toxins and discovery of nephila polyamine toxins 1 and 8 as highly potent inhibitors of ionotropic glutamate receptors
Lucas, S., Poulsen, Mette Homann, Nørager, N. G., Barslund, A. F., Bach, T. B., Kristensen, Anders Skov & Strømgaard, Kristian, 26 Nov 2012, In: Journal of Medicinal Chemistry. 55, 22, p. 10297-10301 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Site-Specific Phosphorylation of PDZ Domains
Ma, S., Strømgaard, Kristian & Clemmensen, L. S., 2020, Expressed Protein Ligation: Methods and Protocols. M. V-P. (ed.). Humana Press, p. 235-261 27 p. (Methods in molecular biology (Clifton, N.J.), Vol. 2133).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Rational design of a heterotrimeric G protein α subunit with artificial inhibitor sensitivity
Malfacini, D., Patt, J., Annala, S., Harpsøe, Kasper, Eryilmaz, F., Reher, R., Crüsemann, M., Hanke, W., Zhang, H., Tietze, D., Gloriam, David E., Bräuner, Hans, Strømgaard, Kristian, König, G. M., Inoue, A., Gomeza, J. & Kostenis, E., 12 Apr 2019, In: The Journal of Biological Chemistry. 294, 15, p. 5747-5758Research output: Contribution to journal › Journal article › Research › peer-review
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Gephyrin-binding peptides visualize postsynaptic sites and modulate neurotransmission
Maric, H. M., Hausrat, T. J., Neubert, F., Dalby, N. O., Doose, S., Sauer, M., Kneussel, M. & Strømgaard, Kristian, 2017, In: Nature Chemical Biology. 13, p. 153-160 11 p., 2246.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular basis of the alternative recruitment of GABA(A) versus glycine receptors through gephyrin
Maric, H., Kasaragod, V. B., Hausrat, T. J., Kneussel, M., Tretter, V., Strømgaard, Kristian & Schindelin, H., 22 Dec 2014, In: Nature Communications. 5, p. 1-11 11 p., 5767.Research output: Contribution to journal › Journal article › Research › peer-review
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Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors
Maric, H., Kasaragod, V. B., Kedström, L. M. H., Hausrat, T. J., Kneussel, M., Schindelin, H. & Strømgaard, Kristian, 7 Jan 2015, In: Angewandte Chemie (International ed. in English). 54, 2, p. 490-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modification of the philanthotoxin-343 polyamine moiety results in different structure-activity profiles at muscle nicotinic ACh, NMDA and AMPA receptors
Mellor, I. R., Brier, T. J., Pluteanu, F., Strømgaard, Kristian, Saghyan, A., Eldursi, N., Brierley, M. J., Andersen, K., Jaroszewski, J. W., Krogsgaard-Larsen, Povl & Usherwood, P. N. R., Jan 2003, In: Neuropharmacology. 44, 1, p. 70-80 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Møller, T. C., Wirth, V. F., Roberts, N. I., Bender, J., Bach, Anders, Jacky, B. P. S., Strømgaard, Kristian, Deussing, J. M., Schwartz, Thue W. & Martinez, Karen Laurence, 2013, In: PLOS ONE. 8, 5, e63352.Research output: Contribution to journal › Journal article › Research › peer-review
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Human Fibrinogen Inhibits Amyloid Assembly of Most Phenol-Soluble Modulins from Staphylococcus aureus
Najarzadeh, Z., Nielsen, J., Farzadfard, A., Sereikaité, Vita, Strømgaard, Kristian, Meyer, R. L. & Otzen, D. E., 2021, In: ACS Omega. 6, 34, p. 21960-21970Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302559
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
Published