René Villadsen

René Villadsen

Associate Professor


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  1. Published

    Transcriptional profiling of transport mechanisms and regulatory pathways in rat choroid plexus

    Andreassen, Søren Norge, Toft-Bertelsen, Trine Lisberg, Wardman, Jonathan Henry, Villadsen, René & MacAulay, Nanna, 2022, In: Fluids and Barriers of the CNS. 19, 1, 19 p., 44.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Evidence of steady-state fibroblast subtypes in the normal human breast as cells-of-origin for perturbed-state fibroblasts in breast cancer

    Bagger, M. M., Sjölund, J., Kim, Jiyoung, Kohler, Katharina Theresa, Villadsen, René, Jafari Kermani, Abbas, Kassem, Moustapha Saad El-Deen, Pietras, K., Rønnov-Jessen, Lone & Petersen, Ole William, 2024, In: Breast Cancer Research. 26, 1, 19 p., 11.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Aggressiveness of non-EMT breast cancer cells relies on FBXO11 activity

    Bagger, Sofie Morsing, Hopkinson, B. M., Pandey, D. P., Bak, M., Brydholm, A. V., Villadsen, René, Helin, K., Rønnov-Jessen, Lone, Petersen, Ole William & Kim, Jiyoung, 2018, In: Molecular Cancer. 17, 1, p. 1-6 6 p., 171.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  4. Published

    A Marker of Endocrine Receptor-Positive Cells, CEACAM6, Is Shared by Two Major Classes of Breast Cancer: Luminal and HER2-Enriched

    Balk-Møller, E., Kim, Jiyoung, Hopkinson, B., Timmermans-Wielenga, V., Petersen, Ole William & Villadsen, René, Apr 2014, In: American Journal of Pathology. 184, 4, p. 1198-1208 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Heterogeneity of CEACAM5 in breast cancer

    Bechmann, M. B., Brydholm, A. V., Codony, V. L., Kim, Jiyoung & Villadsen, René, 2020, In: OncoTarget. 11, 43, p. 3886-3899 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Genesers Histologi

    Brüel, A., Christensen, E. I., Eld, M., Prætorius, J., Qvortrup, Klaus, Tranum-Jensen, Jørgen, Villadsen, René & Geneser, F., 2020, 2 ed. Danmark: Munksgaard . 741 p.

    Research output: Book/Report › Book › Education

  7. Published

    Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment

    De Neergaard, M., Kim, Jiyoung, Villadsen, René, Fridriksdóttir, A. J. R., Rank, F., Timmermans-Wielenga, V., Langerød, A., Børresen-Dale, A., Petersen, Ole William & Rønnov-Jessen, Lone, 2010, In: American Journal of Pathology. 176, 3, p. 1229-1240 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Warburg Effect Metabolism Drives Neoplasia in a Drosophila Genetic Model of Epithelial Cancer

    Eichenlaub, T., Villadsen, René, Freitas, F. C. P., Andrejeva, Diana, Aldana, Blanca, Nguyen, H. T., Petersen, Ole William, Gorodkin, Jan, Herranz, Hector & Cohen, S. M., 2018, In: Current Biology. 28, 20, p. 3220-3228.e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    AXL Is a Driver of Stemness in Normal Mammary Gland and Breast Cancer

    Engelsen, A. S. T., Wnuk-Lipinska, K., Bougnaud, S., Pelissier Vatter, F. A., Tiron, C., Villadsen, R., Miyano, M., Lotsberg, M. L., Madeleine, N., Panahandeh, P., Dhakal, S., Tan, T. Z., Peters, S. D. M., Grøndal, S., Aziz, S. M., Nord, S., Herfindal, L., Stampfer, M. R., Sørlie, T., Brekken, R. A. & 8 others, Straume, O., Halberg, N., Gausdal, G., Thiery, J. P., Akslen, L. A., Petersen, Ole William, LaBarge, M. A. & Lorens, J. B., 2020, In: iScience. 23, 11, 40 p., 101649.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Proof of region-specific multipotent progenitors in human breast epithelia

    Fridriksdottir, A. J., Villadsen, René, Morsing, M., Klitgaard, M. C., Kim, Jiyoung, Petersen, Ole William & Rønnov-Jessen, Lone, 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 47, p. E10102–E10111

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture

    Fridriksdóttir, A. J. R., Kim, Jiyoung, Villadsen, René, Klitgaard, M. C., Hopkinson, B. M., Petersen, Ole William & Rønnov-Jessen, Lone, 2015, In: Nature Communications. 6, 12 p., 8786.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Accumulation of multipotent progenitors with a basal differentiation bias during aging of human mammary epithelia

    Garbe, J. C., Pepin, F., Pelissier, F. A., Sputova, K., Fridriksdottir, A. J., Guo, D. E., Villadsen, René, Park, M., Petersen, Ole William, Borowsky, A. D., Stampfer, M. R. & Labarge, M. A., Jul 2012, In: Cancer Research. 72, 14, p. 3687-701 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Myoepithelial progenitors as founder cells of hyperplastic human breast lesions upon PIK3CA transformation

    Goldhammer, N., Kim, Jiyoung, Villadsen, René, Rønnov-Jessen, Lone & Petersen, Ole William, 2022, In: Communications Biology . 5, 1, 13 p., 219.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Immortalization protocols used in cell culture models of human breast morphogenesis

    Gudjonsson, T., Villadsen, René, Rønnov-Jessen, Lone & Petersen, O. W., 2004, In: Cellular and molecular life sciences : CMLS. 61, 19-20, p. 2523-34 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties

    Gudjonsson, T., Villadsen, René, Nielsen, H. L., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, Ole William, 2002, In: Genes Dev. vol. 16(6), p. 693-706

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition

    Gudjonsson, T., Rønnov-Jessen, Lone, Villadsen, René, Rank, F. E., Bissell, M. J. & Petersen, Ole William, 2002, In: Journal of Cell Science. 115, p. 39-50

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    To create the correct microenvironment: Three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia

    Gudjonsson, T., Rønnov-Jessen, Lone, Villadsen, René, Bissell, M. J. & Petersen, Ole William, 2003, In: Methods. Vol. 30, p. 247-255

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype

    Hopkinson, B. M., Klitgaard, M. C., Petersen, Ole William, Villadsen, René, Rønnov-Jessen, Lone & Kim, Jiyoung, 7 Feb 2017, In: OncoTarget. 8, 6, p. 10580-10593 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland

    Kim, Jiyoung & Villadsen, René, Dec 2018, In: Journal of Histochemistry and Cytochemistry. 66, 12, p. 879-888 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity

    Kim, Jiyoung, Villadsen, René, Sørlie, T., Fogh, L., Grønlund, S. Z., Fridriksdóttir, A. J. R., Kuhn, I., Rank, F., Wielenga, V. T., Solvang, H., Edwards, P. A. W., Børresen-Dale, A., Rønnov-Jessen, Lone, Bissell, M. J. & Petersen, Ole William, 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 16, p. 6124-6129 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The Expression Pattern of Epidermal Differentiation Marker Keratin 10 in the Normal Human Breast and Breast Cancer Cells

    Kim, Jiyoung & Villadsen, René, 2020, In: Journal of Histochemistry and Cytochemistry. 68, 8, p. 561-570

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    SSEA-1 Correlates With the Invasive Phenotype in Breast Cancer

    Kohler, Katharina Theresa, Møller Hansen, A. A., Kim, Jiyoung & Villadsen, René, 2023, In: Journal of Histochemistry and Cytochemistry. 71, 8, 221554231189312.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Ductal keratin 15+ luminal progenitors in normal breast exhibit a basal-like breast cancer transcriptomic signature

    Kohler, Katharina Theresa, Goldhammer, N., Demharter, S., Pfisterer, U., Khodosevich, Konstantin, Rønnov-Jessen, Lone, Petersen, Ole William, Villadsen, René & Kim, Jiyoung, 2022, In: npj Breast Cancer. 8, 1, 12 p., 81.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Human mammary progenitor cell fate decisions are productsof interactions with combinatorial microenvironments

    LaBarge, M. A., Nelson, C. M., Villadsen, René, Rubner Fridriksdottir, A. J., Ruth, J. R., Stampfer, M. R., Petersen, Ole William & Bissell, M. J., 2009, In: Integrative Biology. 1, p. 70-79 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Evidence of two distinct functionally specialized fibroblast lineages in breast stroma

    Morsing, M., Klitgaard, M. C., Jafari Kermani, Abbas, Villadsen, René, Kassem, Moustapha Saad El-Deen, Petersen, Ole William & Rønnov-Jessen, Lone, 2016, In: Breast Cancer Research (Online). 18, 11 p., 108.

    Research output: Contribution to journal › Journal article › Research › peer-review

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