Helle Krogh Johansen

Helle Krogh Johansen

Clinical Professor

Member of:

  • Clinical Microbiology


  1. Published

    Extensive endoscopic image-guided sinus surgery decreases BPI-ANCA in patients with cystic fibrosis

    Aanæs, Kasper, Rasmussen, N., Pressler, T., Segelmark, M., Johansen, Helle Krogh, Lindberg, U., Høiby, Niels, Carlsson, M., Wieslander, J. & Buchwald, C., 2012, In: Scandinavian Journal of Immunology. 76, 6, p. 573-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Clinical effects of sinus surgery and adjuvant therapy in cystic fibrosis patients - can chronic lung infections be postponed?

    Aanæs, Kasper, Johansen, Helle Krogh, Skov, M., Buchvald, F. F., Hjuler, Thomas, Pressler, T., Høiby, Niels, Nielsen, Kim G. & von Buchwald, Christian, 2013, In: Rhinology. 51, 3, p. 222-230 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Secretory IgA as a diagnostic tool for Pseudomonas aeruginosa respiratory colonization

    Aanæs, Kasper, Johansen, Helle Krogh, Poulsen, Steen Seier, Pressler, T., Buchwald, C. & Høiby, Niels, 2012, In: Journal of Cystic Fibrosis. 12, 1, p. 81-87 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Sinus biofilms in patients with cystic fibrosis: is adjusted eradication therapy needed?

    Aanæs, Kasper, Eickhardt, S., Johansen, Helle Krogh, von Buchwald, Christian, Skov, M., Høiby, Niels & Bjarnsholt, Thomas, 2014, In: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The accessibility of topical treatment in the paranasal sinuses on operated cystic fibrosis patients assessed by scintigraphy

    Aanæs, Kasper, Alanin, M. C., Nielsen, Kim G., Jørgensen, M. M., von Buchwald, Christian, Høiby, N., Johansen, Helle Krogh, Johannesen, H. H. & Mortensen, Jann, 2018, In: Rhinology. 56, 3, p. 268-273

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis

    Aanaes, K., von Buchwald, Christian, Hjuler, Thomas, Skov, M., Alanin, M. & Johansen, Helle Krogh, 2013, In: American Journal of Rhinology & Allergy. 27, 1, p. e1-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis

    Aanæs, Kasper, Rickelt, L. F., Johansen, Helle Krogh, von Buchwald, Christian, Pressler, T., Høiby, Niels & Jensen, Peter Østrup, 2011, In: Journal of Cystic Fibrosis. 10, 2, p. 114-120 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A Dedicated Mycosis Flask Increases the Likelihood of Identifying Candidemia Sepsis

    Ahlström, M. G., Antsupova, V. S., Pedersen, M., Johansen, Helle Krogh, Hansen, D. S. & Knudsen, I. J. D., 2023, In: Journal of Fungi. 9, 4, 15 p., 441.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Sinus surgery postpones chronic gram-negative lung infection: Cohort study of 106 patients with cystic fibrosis

    Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G., Taylor-Robinson, D., Waldmann, E., Johansen, Helle Krogh & von Buchwald, Christian, 2016, In: Rhinology. 54, 3, p. 206-213 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia

    Alanin, M. C., Nielsen, K. G., von Buchwald, Christian, Skov, M., Aanæs, Kasper, Høiby, Niels & Johansen, Helle Krogh, Dec 2015, In: Clinical Microbiology and Infection. 21, 12, p. 1093.e1–1093.e7 7 p., 1093.e.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Sinus surgery can improve quality of life, lung infections, and lung function in patients with primary ciliary dyskinesia

    Alanin, M. C., Aanæs, Kasper, Høiby, Niels, Pressler, T., Skov, M., Nielsen, Kim G., Johansen, Helle Krogh & von Buchwald, Christian, Mar 2017, In: International Forum of Allergy Rhinology. 7, 3, p. 240-247

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Simultaneous sinus and lung infections in patients with primary ciliary dyskinesia

    Alanin, M. C., Johansen, Helle Krogh, Aanaes, K., Høiby, Niels, Pressler, T., Skov, M., Nielsen, K. G. & von Buchwald, Christian, Jan 2015, In: Acta Oto-Laryngologica. 135, 1, p. 58-63 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Can secretory immunoglobulin A in saliva predict a change in lung infection status in patients with cystic fibrosis? A prospective pilot study

    Alanin, M. C., Pressler, T., Aanæs, Kasper, Ekstrøm, Claus Thorn, Skov, M., Johansen, Helle Krogh, Nielsen, Kim G., von Buchwald, Christian & Høiby, Niels, 2018, In: Health Services Research. 1, 8, 5 p., e52.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Nanograss sensor for selective detection of Pseudomonas aeruginosa by pyocyanin identification in airway samples

    Alatraktchi, F. A. Z. A., Dimaki, M., Støvring, N., Johansen, Helle Krogh, Molin, S. & Svendsen, W. E., Mar 2020, In: Analytical Biochemistry. 593, 6 p., 113586.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Paper-based sensors for rapid detection of virulence factor produced by Pseudomonas aeruginosa

    Alatraktchi, F. A. Z. A., Noori, J. S., Tanev, G. P., Mortensen, J., Dimaki, M., Johansen, Helle Krogh, Madsen, J., Molin, S. & Svendsen, W. E., 2018, In: PLoS ONE. 13, 3, 9 p., e0194157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Fast Selective Detection of Pyocyanin Using Cyclic Voltammetry

    Alatraktchi, F. A., Andersen, S. B., Johansen, Helle Krogh, Molin, S. & Svendsen, W. E., 19 Mar 2016, In: Sensors. 16, 3, 10 p., 408.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Diversity, prevalence, and longitudinal occurrence of type II toxin-antitoxin systems of Pseudomonas aeruginosa infecting cystic fibrosis lungs

    Andersen, Sandra Breum, Ghoul, M., Griffin, A. S., Petersen, Bent, Johansen, Helle Krogh & Molin, S., 2017, In: Frontiers in Microbiology. 8, 12 p., 1180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Privatisation rescues function following loss of cooperation

    Andersen, Sandra Breum, Ghoul, M., Marvig, R. L., Lee, Z., Molin, S., Johansen, Helle Krogh & Griffin, A. S., 2018, In: eLife. 7, p. 1-27 27 p., e38594.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Long-term social dynamics drive loss of function in pathogenic bacteria

    Andersen, Sandra Breum, Marvig, R. L., Molin, S., Johansen, Helle Krogh & Griffin, A. S., 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 34, p. 10756-10761 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Semi-national surveillance of fungaemia in Denmark 2004-2006: increasing incidence of fungaemia and numbers of isolates with reduced azole susceptibility

    Arendrup, M. C., Fuursted, K., Gahrn-Hansen, B., Schonheyder, H. C., Knudsen, J. D., Jensen, I. M., Bruun, B., Christensen, J. J., Johansen, H. K., Johansen, Helle Krogh & Knudsen, J. D., 2008, In: Clinical Microbiology and Infection. 14, 5, p. 487-494 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    National Surveillance of Fungaemia in Denmark 2004-2009

    Arendrup, M., Christensen, J., Fuursted, K., Johansen, Helle Krogh, Kjeldgaard, P., Knudsen, I. J. D., L, K., Møller, J., Nielsen, L., Olesen, L., Rosenvinge, F., Røder, B., Schønheyder, H., Thomsen, M. & Truberg, K., 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  22. Published

    National surveillance of fungemia in Denmark (2004 to 2009)

    Arendrup, M. C., Bruun, B., Christensen, J. J., Fuursted, K., Johansen, Helle Krogh, Kjaeldgaard, P., Knudsen, J. D., Kristensen, L., Møller, J., Nielsen, L., Rosenvinge, F. S., Røder, B., Schønheyder, H. C., Thomsen, M. & Truberg, K., 1 Jan 2011, In: Journal of Clinical Microbiology. 49, 1, p. 325-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Diagnostic Issues, Clinical Characteristics, and Outcomes for Patients with Fungemia

    Arendrup, M. C., Sulim, S., Holm, A., Nielsen, L., Nielsen, S. D., Knudsen, J. D., Drenck, N. E., Christensen, J. J. & Johansen, Helle Krogh, 1 Sep 2011, In: Journal of Clinical Microbiology. 49, 9, p. 3300-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Primary ciliary dyskinesia patients have the same P. aeruginosa clone in sinuses and lungs

    Arndal, E., Johansen, Helle Krogh, Haagensen, J. A. J., Bartell, J. A., Marvig, R. L., Alanin, M., Aanæs, Kasper, Høiby, Niels, Nielsen, Kim G., Backer, Vibeke & von Buchwald, Christian, 2020, In: The European Respiratory Journal. 55, 1, 4 p., 1901472.

    Research output: Contribution to journalLetterResearchpeer-review

  25. Published

    Update from a 12-year nationwide fungemia surveillance: Increasing intrinsic and acquired resistance causes concern

    Astvad, K. M. T., Johansen, Helle Krogh, Røder, B. L., Rosenvinge, F. S., Knudsen, J. D., Lemming, L., Schønheyder, H. C., Hare, R. K., Kristensen, L., Nielsen, L., Gertsen, J. B., Dzajic, E., Pedersen, M., Østergård, C., Olesen, B., Søndergaard, T. S. & Arendrup, Maiken Cavling, 1 Apr 2018, In: Journal of Clinical Microbiology. 56, 4, 15 p., e01564.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19

    Backer, Vibeke, Sjöbring, U., Sonne, J., Weiss, A., Hostrup, Morten, Johansen, Helle Krogh, Becker, V., Sonne, D. P., Balchen, T., Jellingsø, M. & Sommer, M. O. A., 2021, In: The Lancet Regional Health - Europe. 4, 8 p., 100084.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Evolutionary highways to persistent bacterial infection

    Bartell, J. A., Sommer, L. M., Haagensen, J. A. J., Loch, A., Espinosa, R., Molin, S. & Johansen, Helle Krogh, 2019, In: Nature Communications. 10, 1, 13 p., 629.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Bacterial persisters in long-term infection: Emergence and fitness in a complex host environment

    Bartell, J. A., Cameron, D. R., Mojsoska, B., Haagensen, J. A. J., Pressler, T., Sommer, L. M., Lewis, K., Molin, S. & Johansen, Helle Krogh, 2020, In: PLOS Pathogens. 16, 12 December, e1009112.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Omics-based tracking of Pseudomonas aeruginosa persistence in "eradicated" cystic fibrosis patients

    Bartell, J. A., Sommer, L. M., Marvig, R. L., Skov, M., Pressler, T., Molin, S. & Johansen, Helle Krogh, 2021, In: The European Respiratory Journal. 57, 4, 2000512.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Monitoring meticillin resistant Staphylococcus aureus and its spread in Copenhagen, Denmark, 2013, through routine whole genome sequencing

    Bartels, Mette Damkjær, Larner-Svensson, H., Meiniche, H., Kristoffersen, K., Schønning, Kristian, Nielsen, J. B., Rohde, S. M., Christensen, L. B., Skibsted, A. W., Jarlov, J. O., Johansen, Helle Krogh, Andersen, L. P., Petersen, I. S., Crook, D. W., Bowden, R., Boye, K., Worning, P. & Westh, Henrik T., 30 Apr 2015, In: Eurosurveillance. 20, 17, 9 p., 21112.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Comparing whole-genome sequencing with sanger sequencing for spa typing of methicillin-resistant staphylococcus aureus

    Bartels, Mette Damkjær, Petersen, A., Worning, P., Nielsen, J. B., Larner-Svensson, H., Johansen, Helle Krogh, Andersen, Leif Percival, Jarløv, J. O., Boye, K., Larsen, A. R. & Westh, Henrik T., 1 Dec 2014, In: Journal of clinical microbiology. 52, 12, p. 4305-4308 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Microcontainer Delivery of Antibiotic Improves Treatment of Pseudomonas aeruginosa Biofilms

    Birk, S. E., Haagensen, J. A. J., Johansen, Helle Krogh, Molin, S., Nielsen, L. H. & Boisen, A., May 2020, In: Advanced Healthcare Materials. 9, 10, 10 p., 1901779.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Co-delivery of ciprofloxacin and colistin using microcontainers for bacterial biofilm treatment

    Birk, S. E., Mazzoni, C., Mobasharah Javed, M., Borre Hansen, M., Johansen, Helle Krogh, Anders Juul Haagensen, J., Molin, S., Hagner Nielsen, L. & Boisen, A., 2021, In: International Journal of Pharmaceutics. 599, 120420.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Antibiofilm Properties of Acetic Acid

    Bjarnsholt, Thomas, Alhede, M., Jensen, Peter Østrup, Nielsen, Anne Kirstine, Johansen, Helle Krogh, Homøe, Preben, Høiby, Niels, Givskov, Michael & Kirketerp-Moller, K., Jun 2015, In: Advances in Wound Care. 4, 7, p. 363-372 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Inter-species interactions alter antibiotic efficacy in bacterial communities

    Bottery, M. J., Matthews, J. L., Wood, A. J., Johansen, Helle Krogh, Pitchford, J. W. & Friman, V. P., 2022, In: ISME Journal. 16, p. 812–821

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis

    Burgener, E. B., Sweere, J. M., Bach, M. S., Secor, P. R., Haddock, N., Jennings, L. K., Marvig, R. L., Johansen, Helle Krogh, Rossi, E., Cao, X., Tian, L., Nedelec, L., Molin, S., Bollyky, P. L. & Milla, C. E., 2019, In: Science Translational Medicine. 11, 488, 12 p., eaau9748.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Biofilms in chronic infections - a matter of opportunity - monospecies biofilms in multispecies infections

    Burmølle, Mette, Thomsen, T. R., Fazli, M., Dige, I., Christensen, L., Homøe, Preben, Tvede, M., Nyvad, B., Tolker-Nielsen, Tim, Givskov, Michael, Moser, Claus Ernst, Kirketerp-Møller, K., Johansen, Helle Krogh, Høiby, Niels, Jensen, Peter Østrup, Sørensen, Søren Johannes & Bjarnsholt, Thomas, 2010, In: FEMS Immunology and Medical Microbiology. 59, 3, p. 324-336 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Manzinellaforgiftning kompliceret med streptokokpharyngitis og impetigo

    Bygbjerg, Ib Christian & Johansen, Helle Krogh, 30 Dec 1991, In: Ugeskrift for Laeger. 154, 1, p. 27-8 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    P. aeruginosa in the paranasal sinuses and transplanted lungs have similar adaptive mutations as isolates from chronically infected CF lungs

    Ciofu, Oana, Johansen, Helle Krogh, Aanæs, Kasper, Wassermann, T., Alhede, M., von Buchwald, Christian & Høiby, Niels, 8 Mar 2013, In: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 12, 6, p. 729-736 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Gene transcription profiles of paired mucoid and non-mucoid P. aeruginosa isolates from sinuses and lungs of patients with cystic fibrosis

    Ciofu, O., Johansen, Helle Krogh, Wassermann, T., Aanæs, Kasper, Alhede, M. & Høiby, Niels, 23 May 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  41. Published

    Meropenem in cystic fibrosis patients infected with resistant Pseudomonas aeruginosa or Burkholderia cepacia and with hypersensitivity to beta-lactam antibiotics.

    Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh, Bender Koch, Christian & Høiby, Niels, 1996, In: Clinical Microbiology and Infection. 2, 2, p. 91-98 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Hypermutator Pseudomonas Aeruginosa Exploits Multiple Genetic Pathways To Develop Multidrug Resistance during Long-Term Infections in the Airways of Cystic Fibrosis Patients

    Colque, C. A., Albarracín Orio, A. G., Feliziani, S., Marvig, R. L., Tobares, A. R., Johansen, Helle Krogh, Molin, S. & Smania, A. M., Apr 2020, In: Antimicrobial Agents and Chemotherapy. 64, 5, p. e02142-19

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Longitudinal Evolution of the Pseudomonas-Derived Cephalosporinase (PDC) Structure and Activity in a Cystic Fibrosis Patient Treated with β-Lactams

    Colque, C. A., albarracín Orio, A. G., Tomatis, P. E., Dotta, G., Moreno, D. M., Hedemann, L. G., Hickman, R. A., Sommer, L. M., Feliziani, S., Moyano, A. J., Bonomo, R. A., Johansen, Helle Krogh, Molin, S., Vila, A. J. & Smania, A. M., 2022, In: mBio. 13, 5

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Achromobacter spp. in a Cohort of Non-Selected Pre-and Post-Lung Transplant Recipients

    Crone, C. G., Rezahosseini, O., Schultz, H. H. L., Qvist, T., Johansen, Helle Krogh, Nielsen, Susanne Dam & Perch, Michael, 2022, In: Pathogens. 11, 2, 181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Chronic pulmonary infection with Stenotrophomonas maltophilia and lung function in patients with cystic fibrosis

    Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 1 Sep 2011, In: Journal of Cystic Fibrosis. 10, 5, p. 318-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    A cohort study of the Copenhagen CF Centre eradication strategy against Staphylococcus aureus in patients with CF

    Dalbøge, C. S., Pressler, T., Høiby, Niels, Nielsen, Kim G. & Johansen, Helle Krogh, Jan 2013, In: Journal of Cystic Fibrosis. 12, 1, p. 42-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Chronic infection with Stenotrophomonas maltophilia in patients with cystic fibrosis at the Copenhagen CF centre

    Dalbøge, C. S., Hansen, C. R., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 17 Jun 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  48. Published

    Effects of antibiotic treatment of Staphylococcus aureus infection in patients with cystic fibrosis at the Copenhagen CF centre

    Dalbøge, C. S., Pressler, T., Høiby, Niels & Johansen, Helle Krogh, 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  49. Published

    New concepts in antimicrobial resistance in cystic fibrosis respiratory infections

    Drevinek, P., Canton, R., Johansen, Helle Krogh, Hoffman, L., Coenye, T., Burgel, P. & Davies, J. C., 2022, In: Journal of Cystic Fibrosis. 21, 6, p. 937-945 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    Fungal infection-related mortality versus total mortality as an outcome in trials of antifungal agents

    Due, A. K., Johansen, Helle Krogh & Gøtzsche, P. C., 2006, In: BMC Medical Research Methodology. 6, p. Art no. 40-

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Persistence and genetic adaptation of Pseudomonas aeruginosa in patients with chronic obstructive pulmonary disease

    Eklöf, J., Misiakou, M. A., Sivapalan, P., Armbruster, K., Browatzki, A., Nielsen, T. L., Lapperre, T. S., Andreassen, H. F., Janner, J., Ulrik, C. S., Gabrielaite, M., Johansen, H. K., Jensen, A., Nielsen, T. V., Hertz, F. B., Ghathian, K., Calum, H., Wilcke, T., Seersholm, N., Jensen, J. U. S. & 1 others, Marvig, R. L., 2022, In: Clinical Microbiology and Infection. 28, 7, p. 990-995 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Adaptive Evolution of Pseudomonas aeruginosa in Human Airways Shows Phenotypic Convergence Despite Diverse Patterns of Genomic Changes

    Espaillat, A., Colque, C. A., Rago, D., La Rosa, R., Molin, S. & Johansen, Helle Krogh, 2024, In: MOLECULAR BIOLOGY AND EVOLUTION . 41, 2, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    The small RNA ErsA of Pseudomonas aeruginosa contributes to biofilm development and motility through post-transcriptional modulation of AmrZ

    Falcone, M., Ferrara, S., Rossi, E., Johansen, Helle Krogh, Molin, S. & Bertoni, G., 2018, In: Frontiers in Microbiology. 9, FEB, 238.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Biofilm ved kronisk rhinosinuitis og cystisk fibrose

    Fisker, J., Buchwald, C. V. & Johansen, Helle Krogh, 7 Feb 2011, In: Ugeskrift for Laeger. 173, 6, p. 417-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective

    Folkesson, A., Jelsbak, L., Yang, L., Johansen, Helle Krogh, Ciofu, Oana, Høiby, Niels & Molin, S., Dec 2012, In: Nature Reviews. Microbiology. 10, 12, p. 841-851 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Mutations causing low level antibiotic resistance ensure bacterial survival in antibiotic-treated hosts

    Frimodt-Møller, Jakob, Rossi, E., Haagensen, J. A. J., Falcone, M., Molin, S. & Johansen, Helle Krogh, 2018, In: Scientific Reports. 8, 1, p. 1-13 12512.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Achromobacter spp. genetic adaptation in cystic fibrosis

    Gabrielaite, M., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marvig, R. L., 2021, In: Microbial genomics. 7, 7, 13 p., 000582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Gene loss and acquisition in lineages of pseudomonas aeruginosa evolving in cystic fibrosis patient airways

    Gabrielaite, M., Johansen, Helle Krogh, Molin, S., Nielsen, Finn Cilius & Marvig, R. L., 2020, In: mBio. 11, 5, p. 1-16 16 p., e02359-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Transmission and Antibiotic Resistance of Achromobacter in Cystic Fibrosis

    Gabrielaite, M., Bartell, J. A., Nørskov-Lauritsen, N., Pressler, T., Nielsen, Finn Cilius, Johansen, Helle Krogh & Marviga, R. L., 2021, In: Journal of Clinical Microbiology. 59, 4, e02911-20.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Long-term evolution of antibiotic tolerance in Pseudomonas aeruginosa lung  infections

    Ghoul, M., Andersen, Sandra Breum, Marvig, R. L., Johansen, Helle Krogh, Jelsbak, L., Molin, S., Perron, G. & Griffin, A. S., 2023, In: Evolution Letters. 7, 6, p. 389–400 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance: author's response

    Goltermann, L., Johansen, Helle Krogh, Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, 12, p. 1667-1668 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  62. Published

    Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance

    Goltermann, L., Andersen, Kasper Langebjerg, Johansen, Helle Krogh, Molin, S. & La Rosa, R., 2022, In: Clinical Microbiology and Infection. 28, 12, p. 1594-1601

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Ghost authorship in industry-initiated randomised trials

    Gotzsche, P. C., Hrobjartsson, A., Johansen, Helle Krogh, Haahr, Mette Ewers, Altman, D. G. & Chan, A. W., 2007, In: PLoS Medicine. 4, 1, p. 47-52 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Begrænsninger i publikationsrettighederne i industriinitierede kliniske forsøg: sekundærpublikation

    Gotzsche, P. C., Hrobjartsson, A., Johansen, Helle Krogh, Haahr, M. T., Altman, D. G. & Chan, A. W., 2006, In: Ugeskrift for læger. 168, 25, p. 2467-2469 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Routine versus selective antifungal administration for control of fungal infections in patients with cancer

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-48 48 p., CD000026.

    Research output: Contribution to journalReviewResearchpeer-review

  66. Published

    Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease: Review

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2016, In: Cochrane Database of Systematic Reviews. 9, p. 1-27 27 p., CD007851.

    Research output: Contribution to journalReviewResearchpeer-review

  67. Published

    Intravenous alpha-1 antitrypsin augmentation therapy: systematic review

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1 Sep 2010, In: Danish Medical Bulletin (Online). 57, 9, p. A4175

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Nystatin prophylaxis and treatment in severely immunodepressed patients

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2014, In: Cochrane Database of Systematic Reviews. 9, p. 1-23 23 p., CD002033.

    Research output: Contribution to journalReviewResearchpeer-review

  69. Published

    Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1 Jan 2010, In: Cochrane Database of Systematic Reviews. 7, p. CD007851

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Antifungal prophylactic or empiric therapy vs. placebo or no treatment in cancer patients with neutropenia

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1997, Infectious Diseases Module of the Cochrane Database of Systematic Reviews. Oxford: The Cochrane Collaboration, Issue 2

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  71. Published

    Constraints on publication rights in industry-initiated clinical trials

    Gøtzsche, P. C., Hrobjartsson, A., Johansen, Helle Krogh, Haahr, M. T., Altman, D. G. & Chan, A. W., 2006, In: JAMA - Journal of the American Medical Association. 295, 14, p. 1645-1646 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia

    Gøtzsche, P. C. & Johansen, Helle Krogh, 1997, In: BMJ. British Medical Journal (International Ed.). 314, p. 1238-1244

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    House dust mite control measures for asthma

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2008, In: Cochrane Database of Systematic Reviews. 2, p. CD001187-

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    House dust mite control measures for asthma: systematic review

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2008, In: Allergy. European Journal of Allergy and Clinical Immunology. 63, 6, p. 646-659 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Routine versus selective antifungal administration for control of fungal infections in patients with cancer (Cochrane Review)

    Gøtzsche, P. C. & Johansen, Helle Krogh, 2000, The Cochrane Library, Issue 2. Oxford: Update software, p. -

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  76. Published

    Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate

    Halfon, Y., Jimenez-Fernandez, A., La Rosa, R., Espinosa Portero, R., Johansen, Helle Krogh, Matzov, D., Eyal, Z., Bashan, A., Zimmerman, E., Belousoff, M., Molin, S. & Yonath, A., 29 Oct 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 44, p. 22275-22281 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

    Hansen, S. K., Rau, M. H., Johansen, Helle Krogh, Ciofu, Oana, Jelsbak, L., Yang, L., Folkesson, A., Jarmer, H. Ø., Aanæs, Kasper, von Buchwald, Christian, Høiby, Niels & Molin, S., 2012, In: I S M E Journal. 6, 1, p. 31-45

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Cellular responses of A549 alveolar epithelial cells to serially collected Pseudomonas aeruginosa from cystic fibrosis patients at different stages of pulmonary infection

    Hawdon, N. A., Aval, P. S., Barnes, R. J., Gravelle, S. K., Rosengren, J., Khan, S., Ciofu, Oana, Johansen, Helle Krogh, Høiby, Niels & Ulanova, M., 1 Jul 2010, In: FEMS Immunology and Medical Microbiology. 59, 2, p. 207-20 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Inhalation devices and inhaled corticosteroids particle size influence on severe pneumonia in patients with chronic obstructive pulmonary disease: a nationwide cohort study

    Heerfordt, C. K., Rønn, C., Harboe, Zitta F B Barrella, Ingebrigtsen, T. S., Svorre Jordan, A., Wilcke, Jon Torgny Rostrup, Bonnesen, B., Biering-Sørensen, Tor, Sørensen, Rikke, Holler, J. G., Itenov, Theis Skovsgaard, Johansen, Helle Krogh, Sivapalan, P., Eklöf, J. & Jensen , Jens-Ulrik Stæhr , 2023, In: BMJ Open Respiratory Research. 10, 1, 10 p., e001814. .

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P-aeruginosa lung infection in Cftr(-/-) mice

    Hoffmann, N., Lee, B., Hentzer, M., Rasmussen, T. B., Song, Z. J., Johansen, Helle Krogh, Givskov, M. C. & Høiby, Niels, 2007, In: Antimicrobial Agents and Chemotherapy. 51, 10, p. 3677-3687 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Erratum: Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis (Infection and Immunity (2005) 73, 4 (2504-2514))

    Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, Aug 2005, In: Infection and Immunity. 73, 8, p. 5290 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  82. Published

    Novel mouse model of chronic Pseudomonas aeruginosa lung infection mimicking cystic fibrosis

    Hoffmann, N., Rasmussen, T. B., Jensen, Peter Østrup, Stub, C., Hentzer, M., Molin, S., Ciofu, Oana, Givskov, Michael, Johansen, Helle Krogh & Høiby, Niels, 2005, In: Infection and Immunity. 73, 4, p. 2504-14 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Den 2. kittelrevolution?

    Høiby, Niels, Johansen, Helle Krogh, Tvede, M. & Andersen, Leif Percival, 2008, In: Ugeskrift for læger. 170, 14, p. 1169

    Research output: Contribution to journalComment/debateResearch

  84. Published

    A retrospective review of Achromobacter species and antibiotic treatments in patients with primary ciliary dyskinesia

    Holgersen, M. G., Marthin, J. K., Johansen, Helle Krogh & Nielsen, Kim G., 2021, In: Chronic Respiratory Disease. 18

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Bacterial re-colonization occurs early after lung transplantation in cystic fibrosis patients

    Holm, A. E., Schultz, H. H. L., Johansen, Helle Krogh, Pressler, T., Lund, T. K., Iversen, M. & Perch, Michael, 2021, In: Journal of Clinical Medicine. 10, 6, 11 p., 1275.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Morphological evidence of biofilm formation in Greenlanders with chronic suppurative otitis media

    Homøe, Preben, Bjarnsholt, Thomas, Wessman, M., Sørensen, H. C. F. & Johansen, Helle Krogh, 1 Oct 2009, In: European Archives of Oto-Rhino-Laryngology. 266, 10, p. 1533-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    The relation of biofilms to chronic otitis media and other ear related chronic infections

    Homøe, Preben & Johansen, Helle Krogh, 2010, Biofilm Infections. Springer Publishing Company

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  88. Published

    Use of carbapenems and other antibiotics for pulmonary infections in patients with cystic fibrosis.

    Høiby, Niels, Ciofu, Oana, Jensen, T., Pressler, T., Johansen, Helle Krogh & Koch, C., 1996, In: Pediatric Infectious Disease Journal. 15, 8, p. 738-43 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Pseudomonas aeruginosa and the in vitro and in vivo biofilm mode of growth.

    Høiby, Niels, Johansen, Helle Krogh, Moser, C., Song, Z., Ciofu, Oana & Kharazmi, A., 2001, In: Microbes and Infection. 3, 1, p. 23-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Isolation measures for prevention of infection with respiratory pathogens in cystic fibrosis: a systematic review?

    Høiby, Niels & Johansen, Helle Krogh, 2007, In: Journal of Hospital Infection. 65, 4, p. 374-375 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    The Copenhagen Study Group on antibiotics in sweat: Excretion of beta-lactam antibiotics in sweat - a neglected mechanism for development of antibiotic resistance?

    Høiby, Niels, Pers, C., Johansen, Helle Krogh & Hansen, H., 2000, In: Antimicrobial Agents and Chemotherapy. 44, p. 2855-57

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Pseudomonas aeruginosa Biofilms in the Lungs of Cystic Fibrosis Patients

    Høiby, Niels, Johansen, Helle Krogh, Moser, Claus Ernst, Ciofu, Oana, Jensen, Peter Østrup, Kolpen, Mette, Mandsberg, L., Givskov, Michael, Molin, S. & Bjarnsholt, Thomas, 2011, Biofilm Infections. Springer, p. 167-184 18 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  93. Published

    The clinical impact of bacterial biofilms

    Høiby, Niels, Ciofu, Oana, Johansen, Helle Krogh, Song, Z., Moser, Claus Ernst, Jensen, Peter Østrup, Molin, S., Givskov, Michael, Tolker-Nielsen, Tim & Bjarnsholt, Thomas, 2011, In: International Journal of Oral Science. 3, 2, p. 55-65

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Fremmedlegemeinfektioner--nyt om biofilm og quorum sensing.

    Høiby, Niels, Johansen, Helle Krogh, Ciofu, Oana, Jensen, Peter Østrup, Bjarnsholt, Thomas & Givskov, Michael, 2007, In: Ugeskrift for læger. 169, 48, p. 4163-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Diagnosis of bacterial biofilms in chronic sinusitis and pneumonia

    Høiby, Niels, Buchwald, C. V., Aaanæs, K., Pressler, T. & Johansen, Helle Krogh, 10 Apr 2010. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  96. Published

    Kompendium i mikrobiologi og infektionsmedicin

    Høiby, N., Skinhøj, P., Andersen, Å. B., Andersen, Leif Percival, Arendrup, M. C., Christiansen, C. B., Ciofu, Oana, Gerstoft, Jan, Johansen, Helle Krogh, Kemp, M., Kurtzhals, Jørgen, Nielsen, L. P., Lyngsøe Svejgaard, E., Theander, Thor Grundtvig & Thomsen, Allan Randrup, 2015, 1. ed. FADL's Forlag.

    Research output: Book/ReportBookEducation

  97. Published

    Er indløsning af en ny antibiotikarecept efter behandling med sulfonamid eller pivmecillinam en validere metode til vurdering af behandlingssvigt?

    Høiby, Niels, Tvede, M. & Johansen, Helle Krogh, 2002, In: Ugeskrift for læger. 164, p. 920-921

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Predicting the primary infection source of Escherichia coli bacteremia using virulence-associated genes

    Ilsby, C. S., Hertz, Frederik Boëtius, Westh, Henrik T., Monk, J., Worning, P., Johansen, Helle Krogh, Hansen, Katrine Hartung & Pinholt, M., 2024, In: European Journal of Clinical Microbiology and Infectious Diseases. 43, 4, p. 641-648 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Drug-Driven Phenotypic Convergence Supports Rational Treatment Strategies of Chronic Infections

    Imamovic, L., Ellabaan, M. M. H., Dantas Machado, A. M., Citterio, L., Wulff, T., Molin, S., Johansen, Helle Krogh & Sommer, M. O. A., 11 Jan 2018, In: Cell. 172, 1-2, p. 121-134.e14

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients.

    Jelsbak, L., Johansen, Helle Krogh, Frost, A., Thøgersen, R., Thomsen, Line Elnif, Ciofu, Oana, Yang, L., Haagensen, J. A. J., Høiby, Niels & Molin, S., 2007, In: Infection and Immunity. 75, 5, p. 2214-24 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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