Vilhelm Bohr

Vilhelm Bohr

Affiliate professor

Member of:

  • Web: Center for Healthy Aging

  • Web Track 3: Individualized health


  1. 2015
  2. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function. / Hey-Mogensen, Martin; Gram, Martin; Jensen, Martin Borch; Lund, Michael Taulo; Hansen, Christina Neigaard; Scheibye-Knudsen, Morten; Bohr, Vilhelm A.; Dela, Flemming.

    In: The Journal of Physiology, Vol. 593, No. 17, 01.09.2015, p. 3991-4010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Human exonuclease 1 (EXO1) activity characterization and its function on FLAP structures. / Keijzers, Guido; Bohr, Vilhelm A; Juel Rasmussen, Lene.

    In: Bioscience Reports, Vol. 35, No. 3, e00206, 25.04.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline. / Madsen, Claus Desler; Frederiksen, Jane H; Olsen, Maria Nathalie Angleys; Maynard, Scott; Keijzers, Guido; Fagerlund, Birgitte; Mortensen, Erik Lykke; Osler, Merete; Lauritzen, Martin; Bohr, Vilhelm A; Rasmussen, Lene Juel.

    In: Mitochondrion, Vol. 25, 11.2015, p. 34-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance. / Maynard, S; Keijzers, G; Hansen, Åse Marie; Osler, M; Molbo, D; Bendix, L; Møller, P; Loft, S; Moreno-Villanueva, M; Bürkle, A; Hvitby, Christina Poulsen; Schurman, S H; Stevnsner, Tinna V.; Rasmussen, L J; Avlund, K; Bohr, V A.

    In: Acta Physiologica (Print), Vol. 213, No. 1, 01.2015, p. 156-170.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    DNA Damage, DNA Repair, Aging, and Neurodegeneration. / Maynard, Scott; Fang, Evandro Fei; Scheibye-Knudsen, Morten; Croteau, Deborah L.; Bohr, Vilhelm A.

    In: Cold Spring Harbor Perspectives in Medicine, Vol. 5, No. 10, a025130, 10.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients. / Maynard, Scott; Hejl, Anne-Mette; Dinh, Tran Thuan Son; Keijzers, Guido; Hansen, Åse M; Madsen, Claus Desler; Moreno-Villanueva, Maria; Bürkle, Alexander; Rasmussen, Lene J; Waldemar, Gunhild; Bohr, Vilhelm A.

    In: Aging, Vol. 7, No. 10, 10.2015, p. 793-815.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Protecting the mitochondrial powerhouse. / Scheibye-Knudsen, Morten; Fang, Evandro F.; Croteau, Deborah L.; Wilson, David M.; Bohr, Vilhelm A.

    In: Trends in Cell Biology, Vol. 25, No. 3, 01.03.2015, p. 158-170.

    Research output: Contribution to journalReviewResearchpeer-review

  9. 2014
  10. Published

    Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity. / Aamann, Maria Diget; Hvitby, Christina Poulsen; Popuri, Venkateswarlu; Muftuoglu, Meltem; Lemminger, Lasse Pagh Brøgger; Skeby, Cecilie K; Keijzers, Guido; Ahn, Byungchan; Bjørås, Magnar; Bohr, Vilhelm A; Stevnsner, Tinna V.

    In: Mechanisms of Ageing and Development, Vol. 135, 01.2014, p. 1-14.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair. / Akbari, Mansour; Keijzers, Guido; Maynard, Scott; Scheibye-Knudsen, Morten; Madsen, Claus Desler; Hickson, Ian D; Bohr, Vilhelm A.

    In: DNA Repair, Vol. 16, 04.2014, p. 44-53.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli. / Bendtsen, Kristian Moss; Jensen, Martin Borch; May, Alfred; Rasmussen, Lene Juel; Trusina, Ala; Bohr, Vilhelm; Jensen, Mogens Høgh.

    In: European Biophysics Journal, Vol. 43, No. 10-11, 14.11.2014, p. 509-516.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction. / Fang, Evandro Fei; Scheibye-Knudsen, Morten; Brace, Lear E; Kassahun, Henok; SenGupta, Tanima; Nilsen, Hilde; Mitchell, James R; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Cell, Vol. 157, No. 4, 08.05.2014, p. 882-96.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The role of RecQ helicases in non-homologous end-joining. / Keijzers, Guido; Maynard, Scott; Shamanna, Raghavendra A; Rasmussen, Lene Juel; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Critical Reviews in Biochemistry and Molecular Biology, Vol. 49, No. 6, 11.2014, p. 463-472.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis. / Li, Xiaolin; Fang, Evandro Fei; Scheibye-Knudsen, Morten; Cui, Honghua; Qiu, Lu; Li, Jian; He, Yuping; Huang, Jing; Bohr, Vilhelm A.; Ng, Tzi Bun; Guo, Hongwei.

    In: Scientific Reports, Vol. 4, 6434, 2014.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome. / Scheibye-Knudsen, Morten; Mitchell, Sarah J.; Fang, Evandro F.; Iyama, Teruaki; Ward, Theresa; Wang, James; Dunn, Christopher A.; Singh, Nagendra; Veith, Sebastian; Hasan-Olive, Md Mahdi; Mangerich, Aswin; Wilson, Mark A.; Mattson, Mark P.; Bergersen, Linda H.; Cogger, Victoria C.; Warren, Alessandra; Le Couteur, David G.; Moaddel, Ruin; Wilson, David M.; Croteau, Deborah L.; De Cabo, Rafael; Bohr, Vilhelm A.

    In: Cell Metabolism, Vol. 20, No. 5, 04.11.2014, p. 840-855.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders. / Scheibye-Knudsen, Morten; Fang, Evandro Fei; Croteau, Deborah L.; Bohr, Vilhelm A.

    In: Autophagy, Vol. 10, No. 8, 2014, p. 1468-1469.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    RECQ HELICASE RECQL4 PARTICIPATES IN NON-HOMOLOGOUS END JOINING AND INTERACTS WITH THE KU COMPLEX. / Shamanna, Raghavendra A; Singh, Dharmendra Kumar; Lu, Huiming; Mirey, Gladys; Keijzers, Guido; Salles, Bernard; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Carcinogenesis, Vol. 35, No. 11, 11.2014, p. 2415-2424.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2013
  20. Published

    Bohr på ny. / Bohr, Vilhelm; Bohr, Tomas; Topsøe, Haldor; Bruun, Lone ; Knudsen, Henrik; Nielsen, Henry ; Aaserud, Finn; Grandin, Karl; von Bülow, Hans; Kragh, Helge; Andersen, Anja C.; Mølmer, Klaus; Favrholdt, David; Faye, Jan; Zinkernagel, Henrik.

    København : Forlaget Epsilon.Dk, 2013.

    Research output: Book/ReportBookCommunication

  21. Published

    Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells. / Maynard, Scott; Keijzers, Guido; Gram, Martin; Madsen, Claus Desler; Bendix, Laila; Budtz-Jørgensen, Esben; Molbo, Drude; Croteau, Deborah L; Osler, Merete; Stevnsner, Tinna V.; Rasmussen, Lene Juel; Dela, Flemming; Avlund, Kirsten; Bohr, Vilhelm A.

    In: Aging, 30.11.2013, p. 850-864.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells. / Nguyen, Giang Huong; Dexheimer, Thomas S; Rosenthal, Andrew S; Chu, Wai Kit; Singh, Dharmendra Kumar; Mosedale, Georgina; Bachrati, Csanád Z; Schultz, Lena; Sakurai, Masaaki; Savitsky, Pavel; Abu, Mika; McHugh, Peter J; Bohr, Vilhelm A; Harris, Curtis C; Jadhav, Ajit; Gileadi, Opher; Maloney, David J; Simeonov, Anton; Hickson, Ian D.

    In: Chemistry & Biology, Vol. 20, No. 1, 24.01.2013, p. 55-62.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    DNA damage response, bioenergetics, and neurological disease : the challenge of maintaining brain health in an aging human population. / Rasmussen, Lene Juel; Shiloh, Yosef; Bergersen, Linda H; Sander, Miriam; Bohr, Vilhelm A; Tønjum, Tone.

    In: Mechanisms of Ageing and Development, Vol. 134, No. 10, 10.2013, p. 427-33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Modulation of DNA base excision repair during neuronal differentiation. / Sykora, Peter; Yang, Jenq-Lin; Ferrarelli, Leslie K; Tian, Jingyan; Tadokoro, Takashi; Kulkarni, Avanti; Weissman, Lior; Keijzers, Guido; Wilson, David M; Mattson, Mark P; Bohr, Vilhelm A.

    In: Neurobiology of Aging, Vol. 34, No. 7, 07.2013, p. 1717-27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2012
  26. Published

    14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif. / Andersen, Sofie Dabros; Keijzers, Guido; Rampakakis, Emmanouil; Engels, Kim; Luhn, Patricia; El-Shemerly, Mahmoud; Nielsen, Finn Cilius; Du, Yuhong; May, Alfred; Bohr, Vilhelm A; Ferrari, Stefano; Zannis-Hadjopoulos, Maria; Fu, Haian; Rasmussen, Lene Juel.

    In: D N A Repair, Vol. 11, No. 3, 03.2012, p. 267-77.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity. / Croteau, Deborah L; Rossi, Marie L; Canugovi, Chandrika; Tian, Jane; Sykora, Peter; Ramamoorthy, Mahesh; Wang, Zheng Ming; Singh, Dharmendra Kumar; Akbari, Mansour; Kasiviswanathan, Rajesh; Copeland, William C; Bohr, Vilhelm A.

    In: Aging Cell, Vol. 11, No. 3, 2012, p. 456-66.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients. / Jensen, Martin Borch; Dunn, Christopher A; Keijzers, Guido; Kulikowicz, Tomasz; Rasmussen, Lene Juel; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Aging, Vol. 4, No. 11, 11.2012, p. 790-802.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy. / Scheibye-Knudsen, Morten; Ramamoorthy, Mahesh; Sykora, Peter; Maynard, Scott; Lin, Ping-Chang; Minor, Robin K; Wilson, David M; Cooper, Marcus; Spencer, Richard; de Cabo, Rafael; Croteau, Deborah L; Bohr, Vilhelm A.

    In: The Journal of Experimental Medicine, Vol. 209, No. 4, 04.2012, p. 855-69.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4975983