Vilhelm Bohr

Vilhelm Bohr

Affiliate professor

Member of:

  • Web: Center for Healthy Aging

  • Web Track 3: Individualized health


  1. 2019
  2. E-pub ahead of print

    Lamin A/C promotes DNA base excision repair. / Maynard, Scott; Keijzers, Guido; Akbari, Mansour; Ezra, Michael Ben; Hall, Arnaldur; Morevati, Marya; Scheibye-Knudsen, Morten; Gonzalo, Susana; Bartek, Jiri; Bohr, Vilhelm A.

    In: Nucleic Acids Research, 24.10.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print

    Mitochondria in the signaling pathways that control longevity and health span. / Akbari, Mansour; Kirkwood, Thomas B L; Bohr, Vilhelm A.

    In: Ageing Research Reviews, 12.08.2019, p. 100940.

    Research output: Contribution to journalReviewResearchpeer-review

  4. E-pub ahead of print

    Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease. / Fang, Evandro F; Hou, Yujun; Palikaras, Konstantinos; Adriaanse, Bryan A; Kerr, Jesse S; Yang, Beimeng; Lautrup, Sofie; Hasan-Olive, Md Mahdi; Caponio, Domenica; Dan, Xiuli; Rocktäschel, Paula; Croteau, Deborah L; Akbari, Mansour; Greig, Nigel H; Fladby, Tormod; Nilsen, Hilde; Cader, M Zameel; Mattson, Mark P; Tavernarakis, Nektarios; Bohr, Vilhelm A.

    In: Nature Neuroscience, 11.02.2019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells. / Zheng, Jin; Croteau, Deborah L; Bohr, Vilhelm; Akbari, Mansour.

    In: Nucleic Acids Research, Vol. 47, No. 8, 2019, p. 4086–4110.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Emerging Antitumor Activities of the Bitter Melon (Momordica charantia). / Fang, Evandro Fei; Froetscher, Lynn; Scheibye-Knudsen, Morten; Bohr, Vilhelm A; Wong, Jack Ho; Ng, Tzi Bun.

    In: Current Protein and Peptide Science, Vol. 20, No. 3, 2019, p. 296-301.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2018
  8. Published

    NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency. / Hou, Yujun; Lautrup, Sofie; Cordonnier, Stephanie; Wang, Yue; Croteau, Deborah L.; Zavala, Eduardo; Zhang, Yongqing; Moritoh, Kanako; O’Connell, Jennifer F.; Baptiste, Beverly A.; Stevnsner, Tinna V.; Mattson, Mark P.; Bohr, Vilhelm A.

    In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 8, 2018, p. E1876-E1885.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Sarcopenia, Aging and Prospective Interventional Strategies. / Waltz, Tyler B; Fivenson, Elayne M; Morevati, Marya; Li, Chuanhao; Becker, Kevin G; Bohr, Vilhelm A; Fang, Evandro F.

    In: Current Medicinal Chemistry, Vol. 25, No. 40, 2018, p. 5588-5596.

    Research output: Contribution to journalReviewResearchpeer-review

  10. 2017
  11. Published

    DNA polymerase beta participates in mitochondrial DNA repair. / Sykora, P; Kanno, S; Akbari, M; Kulikowicz, T; Baptiste, B A; Leandro, G S; Lu, H; Tian, J; May, A; Becker, K A; Croteau, D L; Wilson, D M; Sobol, R W; Yasui, A; Bohr, V A.

    In: Molecular and Cellular Biology, Vol. 37, No. 16, e00237-17, 08.2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Cockayne syndrome : Clinical features, model systems and pathways. / Karikkineth, Ajoy C; Scheibye-Knudsen, Morten; Fivenson, Elayne; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Ageing Research Reviews, Vol. 33, 01.2017, p. 3-17.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    Genome instability in Alzheimer disease. / Hou, Yujun; Song, Hyundong; Croteau, Deborah L; Akbari, Mansour; Bohr, Vilhelm A.

    In: Mechanisms of Ageing and Development, Vol. 161, No. part A, 01.2017, p. 83-94.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice. / Fang, Evandro F.; Palikaras, Konstantinos; Sun, Nuo; Fivenson, Elayne M.; Spangler, Ryan D.; Kerr, Jesse S.; Cordonnier, Stephanie A.; Hou, Yujun; Dombi, Eszter; Kassahun, Henok; Tavernarakis, Nektarios; Poulton, Joanna; Nilsen, Hilde; Bohr, Vilhelm A.

    In: Journal of Visualized Experiments, No. 129, e56301, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Mitophagy and Alzheimer's Disease : Cellular and Molecular Mechanisms. / Kerr, Jesse S.; Adriaanse, Bryan A.; Greig, Nigel H.; Mattson, Mark P.; Cader, M. Zameel; Bohr, Vilhelm A.; Fang, Evandro F.

    In: Trends in Neurosciences, Vol. 40, No. 3, 2017, p. 151-166.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Mitophagy in neurodegeneration and aging. / Fivenson, Elayne M; Lautrup, Sofie; Sun, Nuo; Scheibye-Knudsen, Morten; Stevnsner, Tinna; Nilsen, Hilde; Bohr, Vilhelm A; Fang, Evandro Fei.

    In: Neurochemistry International, Vol. 109, 2017, p. 202-209.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    NAD+ in Aging : Molecular Mechanisms and Translational Implications. / Fang, Evandro F.; Lautrup, Sofie; Hou, Yujun; Demarest, Tyler G.; Croteau, Deborah L.; Mattson, Mark P.; Bohr, Vilhelm A.

    In: Trends in Molecular Medicine, Vol. 23, No. 10, 2017, p. 899-916.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis. / Fakouri, Nima Borhan; Durhuus, Jon Ambaek; Regnell, Christine Elisabeth; Angleys, Maria; Desler, Claus; Hasan-Olive, Mahdi; Martin-Pardillos, Ana; Tsaalbi-Shtylik, Anastasia; Thomsen, Kirsten; Lauritzen, Martin; Bohr, Vilhelm A.; de Wind, Niels; Bergersen, Linda Hildegard; Rasmussen, Lene Juel.

    In: Scientific Reports, Vol. 7, 12480, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway. / Fang, Evandro Fei; Waltz, Tyler B; Kassahun, Henok; Lu, Qiping; Kerr, Jesse S; Morevati, Marya; Fivenson, Elayne M; Wollman, Bradley N; Marosi, Krisztina; Wilson, Mark A; Iser, Wendy B; Eckley, David Mark; Zhang, Yongqing; Lehrmann, Elin; Goldberg, Ilya G.; Scheibye-Knudsen, Morten; Mattson, Mark P.; Nilsen, Hilde; Bohr, Vilhelm A; Becker, Kevin G.

    In: Scientific Reports, Vol. 7, 46208, 2017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2016
  21. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain. / Lauritzen, Knut H.; Hasan-Olive, Md Mahdi; Regnell, Christine E.; Kleppa, Liv; Scheibye-Knudsen, Morten; Gjedde, Albert; Klungland, Arne; Bohr, Vilhelm A.; Storm-Mathisen, Jon; Bergersen, Linda H.

    In: Neurobiology of Aging, Vol. 48, 12.2016, p. 34-47.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA. / Scheibye-Knudsen, Morten; Tseng, Anne; Jensen, Martin Borch; Scheibye-Alsing, Karsten; Fang, Evandro Fei; Iyama, Teruaki; Bharti, Sanjay Kumar; Marosi, Krisztina; Froetscher, Lynn; Kassahun, Henok; Eckley, David Mark; Maul, Robert W.; Bastian, Paul; De, Supriyo; Ghosh, Soumita; Nilsen, Hilde; Goldberg, Ilya G.; Mattson, Mark P.; Wilson, David M., III; Brosh, Robert M., Jr.; Gorospe, Myriam; Bohr, Vilhelm A.

    In: National Academy of Sciences. Proceedings, Vol. 113, No. 44, 01.11.2016, p. 12502-12507.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    NAD(+) Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. / Fang, Evandro Fei; Kassahun, Henok; Croteau, Deborah L; Scheibye-Knudsen, Morten; Marosi, Krisztina; Lu, Huiming; Shamanna, Raghavendra A; Kalyanasundaram, Sumana; Bollineni, Ravi Chand; Wilson, Mark A; Iser, Wendy B; Wollman, Bradley N; Morevati, Marya; Li, Jun; Kerr, Jesse S; Lu, Qiping; Waltz, Tyler B; Tian, Jane; Sinclair, David A; Mattson, Mark P; Nilsen, Hilde; Bohr, Vilhelm A.

    In: Cell Metabolism, Vol. 24, No. 4, 11.10.2016, p. 566-581.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks. / Lu, Huiming; Shamanna, Raghavendra A; Keijzers, Guido; Anand, Roopesh; Rasmussen, Lene Juel; Cejka, Petr; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Cell Reports, Vol. 16, No. 1, 28.06.2016, p. 161-173.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Acquired Localized Cutis Laxa due to Increased Elastin Turnover. / Nygaard, Rie Harboe; Maynard, Scott; Schjerling, Peter; Kjær, Michael; Qvortrup, Klaus; Bohr, Vilhelm A; Rasmussen, Lene J; Jemec, Gregor B E; Heidenheim, Michael.

    In: Case Reports in Dermatology, Vol. 8, No. 1, 14.06.2016, p. 42-51.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Nuclear DNA damage signalling to mitochondria in ageing. / Fang, Evandro Fei; Scheibye-Knudsen, Morten; Chua, Katrin F; Mattson, Mark P; Croteau, Deborah L; Bohr, Vilhelm A.

    In: Nature Reviews. Molecular Cell Biology, Vol. 17, No. 5, 05.2016, p. 308-321.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2015
  28. A research agenda for aging in China in the 21st century. / Fang, Evandro Fei; Scheibye-Knudsen, Morten; Jahn, Heiko J; Li, Juan; Ling, Li; Guo, Hongwei; Zhu, Xinqiang; Preedy, Victor; Lu, Huiming; Bohr, Vilhelm A; Chan, Wai Yee; Liu, Yuanli; Ng, Tzi Bun.

    In: Ageing Research Reviews, Vol. 24, No. Pt B, 11.2015, p. 197-205.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline. / Madsen, Claus Desler; Frederiksen, Jane H; Olsen, Maria Nathalie Angleys; Maynard, Scott; Keijzers, Guido; Fagerlund, Birgitte; Mortensen, Erik Lykke; Osler, Merete; Lauritzen, Martin; Bohr, Vilhelm A; Rasmussen, Lene Juel.

    In: Mitochondrion, Vol. 25, 11.2015, p. 34-7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    DNA Damage, DNA Repair, Aging, and Neurodegeneration. / Maynard, Scott; Fang, Evandro Fei; Scheibye-Knudsen, Morten; Croteau, Deborah L.; Bohr, Vilhelm A.

    In: Cold Spring Harbor Perspectives in Medicine, Vol. 5, No. 10, a025130, 10.2015.

    Research output: Contribution to journalJournal articleResearchpeer-review

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