Synthesis of azaphenanthridines via anionic ring closure
Research output: Contribution to journal › Journal article › Research › peer-review
A new and convergent synthesis of azaphenanthridines via an anionic ring closure is reported. Ortho-lithiation/in situ borylation of cyanopyridines produces the corresponding cyanopyridylboronic esters, which undergo a Suzuki-Miyaura cross-coupling to give the key intermediates. Addition of lithium morpholide produces the azaphenanthridines.
Original language | English |
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Journal | Tetrahedron |
Volume | 61 |
Issue number | 42 |
Pages (from-to) | 9955-9960 |
Number of pages | 6 |
ISSN | 0040-4020 |
DOIs | |
Publication status | Published - 17 Oct 2005 |
ID: 45437443