Regulation of T cell migration during viral infection: role of adhesion molecules and chemokines
Research output: Contribution to journal › Journal article › Research › peer-review
T cell mediated immunity and in particular CD8+ T cells are pivotal for the control of most viral infections. T cells exclusively exert their antiviral effect through close cellular interaction with relevant virus-infected target cells in vivo. It is therefore imperative that efficient mechanisms exist, which will rapidly direct newly generated effector T cells to sites of viral replication. In the present report we have reviewed our present knowledge concerning the molecular interactions, which are important in targeting of effector CD8+ T cells to sites of viral infection.
Original language | English |
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Journal | Immunology Letters |
Volume | 85 |
Issue number | 2 |
Pages (from-to) | 119-27 |
Number of pages | 8 |
ISSN | 0165-2478 |
Publication status | Published - 2003 |
Bibliographical note
Keywords: Animals; CD8-Positive T-Lymphocytes; Cell Adhesion Molecules; Cell Movement; Chemokines; Humans; Integrins; Receptors, Chemokine; Selectins; T-Lymphocyte Subsets; Virus Diseases; Viruses
ID: 9639344