Klonal hæmatopoiese som mulig risikofaktor for hjerte-kar-sygdom
Research output: Contribution to journal › Journal article › Research › peer-review
The ageing process is associated with somatic mutations in haematopoietic stem cells, which can lead to clonal haematopoiesis. Recently, clonal haematopoiesis has emerged as a risk factor for cardiovascular disease, and the underlying mechanisms likely involve heightened inflammatory responses in leukocytes derived from mutated clones. This review outlines the concept of clonal haematopoiesis of indeterminate potential and summarises epidemiological and experimental evidence, which support the notion that clonal haematopoiesis-mediated inflammation contributes to cardiovascular disease.
Translated title of the contribution | Clonal haematopoiesis is possibly a risk factor for cardiovascular disease |
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Original language | Danish |
Article number | V04200299 |
Journal | Ugeskrift for Laeger |
Volume | 182 |
Issue number | 34 |
Number of pages | 7 |
ISSN | 0041-5782 |
Publication status | Published - 2020 |
Links
- https://ugeskriftet.dk/files/scientific_article_files/2021-02/v04200299_webx.pdf
Final published version
ID: 269690839