Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs
Research output: Contribution to journal › Journal article › Research › peer-review
Identification of patients at risk for drug-induced torsades de pointes arrhythmia (TdP) is difficult. Increased temporal lability of repolarization has been suggested as being valuable to predict proarrhythmia. The predictive value of different repolarization parameters, including beat-to-beat variability of repolarization (BVR), was compared in this serial investigation in dogs with chronic AV block.
|Number of pages||7|
|Publication status||Published - 19 Oct 2004|
- Action Potentials, Adrenergic beta-Antagonists, Animals, Cardiac Complexes, Premature, Chronic Disease, Disease Susceptibility, Dogs, Dose-Response Relationship, Drug, Electrocardiography, Female, Heart Block, Heart Conduction System, Heart Ventricles, Male, Predictive Value of Tests, Sotalol, Torsades de Pointes