Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs

Research output: Contribution to journalJournal articleResearchpeer-review

Identification of patients at risk for drug-induced torsades de pointes arrhythmia (TdP) is difficult. Increased temporal lability of repolarization has been suggested as being valuable to predict proarrhythmia. The predictive value of different repolarization parameters, including beat-to-beat variability of repolarization (BVR), was compared in this serial investigation in dogs with chronic AV block.
Original languageEnglish
Issue number16
Pages (from-to)2453-9
Number of pages7
Publication statusPublished - 19 Oct 2004

    Research areas

  • Action Potentials, Adrenergic beta-Antagonists, Animals, Cardiac Complexes, Premature, Chronic Disease, Disease Susceptibility, Dogs, Dose-Response Relationship, Drug, Electrocardiography, Female, Heart Block, Heart Conduction System, Heart Ventricles, Male, Predictive Value of Tests, Sotalol, Torsades de Pointes

ID: 45965630