Gene delivery by electroporation
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
By applying brief electric pulses, it is possible to transfer molecules into cells and tissues. The use of electroporation for delivery of chemotherapy is now quite widely used and in further development. Electrochemotherapy is in routine use for cutaneous tumors [1] in more than 100 cancer centers, and several thousand patients have been treated. Response rates are high and side effects limited [2-8]. An important perspective about the success of electrochemotherapy is that electroporation equipment approved for clinical use is now available in many hospitals, allowing its use for gene therapy.
Original language | English |
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Title of host publication | Drug Delivery : An Integrated Clinical and Engineering Approach |
Number of pages | 8 |
Publisher | CRC Press |
Publication date | 1 Jan 2017 |
Pages | 341-348 |
ISBN (Print) | 9781466565944 |
ISBN (Electronic) | 9781466565951 |
DOIs | |
Publication status | Published - 1 Jan 2017 |
Bibliographical note
Publisher Copyright:
© 2017 by Taylor & Francis Group, LLC.
ID: 318949036