Gene delivery by electroporation

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

By applying brief electric pulses, it is possible to transfer molecules into cells and tissues. The use of electroporation for delivery of chemotherapy is now quite widely used and in further development. Electrochemotherapy is in routine use for cutaneous tumors [1] in more than 100 cancer centers, and several thousand patients have been treated. Response rates are high and side effects limited [2-8]. An important perspective about the success of electrochemotherapy is that electroporation equipment approved for clinical use is now available in many hospitals, allowing its use for gene therapy.

Original languageEnglish
Title of host publicationDrug Delivery : An Integrated Clinical and Engineering Approach
Number of pages8
PublisherCRC Press
Publication date1 Jan 2017
Pages341-348
ISBN (Print)9781466565944
ISBN (Electronic)9781466565951
DOIs
Publication statusPublished - 1 Jan 2017

Bibliographical note

Publisher Copyright:
© 2017 by Taylor & Francis Group, LLC.

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