Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine. / Clementson, Sebastian; Jessing, Mikkel; Pedersen, Henrik; Vital, Paulo; Kristensen, Jesper L.

In: Journal of the American Chemical Society, Vol. 141, No. 22, 05.2019, p. 8783-8786.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Clementson, S, Jessing, M, Pedersen, H, Vital, P & Kristensen, JL 2019, 'Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine', Journal of the American Chemical Society, vol. 141, no. 22, pp. 8783-8786. https://doi.org/10.1021/jacs.9b04626

APA

Clementson, S., Jessing, M., Pedersen, H., Vital, P., & Kristensen, J. L. (2019). Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine. Journal of the American Chemical Society, 141(22), 8783-8786. https://doi.org/10.1021/jacs.9b04626

Vancouver

Clementson S, Jessing M, Pedersen H, Vital P, Kristensen JL. Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine. Journal of the American Chemical Society. 2019 May;141(22):8783-8786. https://doi.org/10.1021/jacs.9b04626

Author

Clementson, Sebastian ; Jessing, Mikkel ; Pedersen, Henrik ; Vital, Paulo ; Kristensen, Jesper L. / Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine. In: Journal of the American Chemical Society. 2019 ; Vol. 141, No. 22. pp. 8783-8786.

Bibtex

@article{4b83fef242fe453bbfedafd3db489287,
title = "Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine",
abstract = "Erythrina alkaloids represent a rich source of complex polycyclic, bioactive natural products. In addition to their sedative and hypotensive effect, their curare-like activity and structural framework have made them attractive targets for synthetic and medicinal chemists. (+)-Dihydro-β-erythroidine (DHβE), the most potent nicotine acetylcholine receptor antagonist (nAChR) of the Erythrina family, is synthesized for the first time in 13 steps from commercially available material.",
author = "Sebastian Clementson and Mikkel Jessing and Henrik Pedersen and Paulo Vital and Kristensen, {Jesper L}",
year = "2019",
month = may,
doi = "10.1021/jacs.9b04626",
language = "English",
volume = "141",
pages = "8783--8786",
journal = "Journal of the American Chemical Society",
issn = "0002-7863",
publisher = "ACS Publications",
number = "22",

}

RIS

TY - JOUR

T1 - Enantioselective Total Synthesis of (+)-Dihydro-β-erythroidine

AU - Clementson, Sebastian

AU - Jessing, Mikkel

AU - Pedersen, Henrik

AU - Vital, Paulo

AU - Kristensen, Jesper L

PY - 2019/5

Y1 - 2019/5

N2 - Erythrina alkaloids represent a rich source of complex polycyclic, bioactive natural products. In addition to their sedative and hypotensive effect, their curare-like activity and structural framework have made them attractive targets for synthetic and medicinal chemists. (+)-Dihydro-β-erythroidine (DHβE), the most potent nicotine acetylcholine receptor antagonist (nAChR) of the Erythrina family, is synthesized for the first time in 13 steps from commercially available material.

AB - Erythrina alkaloids represent a rich source of complex polycyclic, bioactive natural products. In addition to their sedative and hypotensive effect, their curare-like activity and structural framework have made them attractive targets for synthetic and medicinal chemists. (+)-Dihydro-β-erythroidine (DHβE), the most potent nicotine acetylcholine receptor antagonist (nAChR) of the Erythrina family, is synthesized for the first time in 13 steps from commercially available material.

U2 - 10.1021/jacs.9b04626

DO - 10.1021/jacs.9b04626

M3 - Journal article

C2 - 31122014

VL - 141

SP - 8783

EP - 8786

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

SN - 0002-7863

IS - 22

ER -

ID: 218709893